Homo sapiens         E3 activity/A20

※ E3 activity/A20 family introduction

    The A20 family represents the zinc finger domain found in A20 (1). A20 is an inhibitor of cell death that inhibits NF-kappaB activation via the tumour necrosis factor receptor associated factor pathway (2). The zinc finger domains appear to mediate self-association in A20. These fingers also mediate IL-1-induced NF-kappa B activation.

1. http://pfam.xfam.org/family/PF01754

2. Ananda S. Prasad (2007). Zinc: mechanisms of host defense. The Journal of Nutrition., 137(5):1345-1349. PMID:17449604



There are 2 genes.  Reviewed (2)  or Unreviewed (0) Download the gene list
StatusiUUCD IDEnsemble Gene IDUniProt AccessionGene Name
IUUC-Hsa-046997
ENSG00000243335.8
Q9UJ41
KCTD7; RABGEF1; RABEX5
IUUC-Hsa-046071
ENSG00000118503.14
P21580
TNFAIP3; OTUD7C; A20