Homo sapiens         E3 activity/RING/PHD

※ E3 activity/RING/PHD family introduction

    The plant homeodomain (PHD) zinc finger domain has a C4HC3-type motif, and is widely distributed in eukaryotes, being found in many chromatin regulatory factors (1).PHD is thought to be involved in chromatin-mediated transcriptional regulation (2). The PHD finger motif is reminiscent of, but distinct from the C3HC4 type RING finger.

1. http://pfam.xfam.org/family/PF00628

2. Rein Aasland, Toby J. Gibson, A.Francis Stewart (1995). The PHD finger: Implications for chromatin-mediated transcriptional regulation. Trends in Biochemical Sciences., 20(2):56-59. PMID:77015622



There are 52 genes.  Reviewed (14)  or Unreviewed (38) Download the gene list
StatusiUUCD IDEnsemble Gene IDUniProt AccessionGene Name
IUUC-Hsa-046765
ENSG00000130726.11
Q13263
TRIM28; KAP1; RNF96; TIF1B
IUUC-Hsa-046988
ENSG00000272333.5
Q9UMN6
KMT2B; HRX2; KIAA0304; MLL2; MLL4; TRX2; WBP7
IUUC-Hsa-045671
ENSG00000095015.5
Q13233
MAP3K1; MAPKKK1; MEKK; MEKK1
IUUC-Hsa-046852
ENSG00000111653.19
Q9UNL4
ING4; My036
IUUC-Hsa-046143
ENSG00000118058.20
Q03164
KMT2A; ALL1; CXXC7; HRX; HTRX; MLL; MLL1; TRX1
IUUC-Hsa-046325
ENSG00000099364.16
Q6PCT2
FBXL19; FBL19
IUUC-Hsa-045877
ENSG00000089094.17
Q8NHM5
KDM2B; CXXC2; FBL10; FBXL10; JHDM1B; PCCX2
IUUC-Hsa-046170
ENSG00000153487.12
Q9UK53
ING1
IUUC-Hsa-046302
ENSG00000198060.9
Q9NX47
MARCH5; RNF153
IUUC-Hsa-046169
ENSG00000197323.11
Q9UPN9
TRIM33; KIAA1113; RFG7; TIF1G
IUUC-Hsa-046785
ENSG00000122779.17
O15164
TRIM24; RNF82; TIF1; TIF1A
IUUC-Hsa-046603
ENSG00000160224.16
O43918
AIRE; APECED
IUUC-Hsa-046422
ENSG00000147854.16
Q96PU4
UHRF2; NIRF; RNF107
IUUC-Hsa-047032
ENSG00000070047.11
Q9P1Y6
PHRF1; KIAA1542
IUUC-Hsa-046740
ENSG00000106443.15
A0A0U1RRH6
PHF14
IUUC-Hsa-046789
ENSG00000274780.2
B7ZM65
PHRF1
IUUC-Hsa-046855
ENSG00000205683.11
Q92784
DPF3; BAF45C; CERD4
IUUC-Hsa-045908
ENSG00000111642.14
A0A0C4DGG9
CHD4
IUUC-Hsa-046399
ENSG00000012817.15
Q9BY66-3
KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
IUUC-Hsa-046180
ENSG00000173120.14
Q9Y2K7
KDM2A; CXXC8; FBL7; FBXL11; JHDM1A; KIAA1004
IUUC-Hsa-045954
ENSG00000077684.15
Q6IE81
JADE1; KIAA1807; PHF17
IUUC-Hsa-046380
ENSG00000109685.17
O96028
WHSC1; NSD2; KIAA1090; MMSET; TRX5
IUUC-Hsa-046436
ENSG00000165671.18
Q96L73
NSD1; ARA267; KMT3B
IUUC-Hsa-046188
ENSG00000225553.7
O43189
PHF1; PCL1
IUUC-Hsa-046675
ENSG00000135365.15
Q96BD5
PHF21A; BHC80; KIAA1696; BM-006
IUUC-Hsa-045933
ENSG00000166436.15
B5MCJ9
TRIM66
IUUC-Hsa-045821
ENSG00000073614.12
P29375
KDM5A; JARID1A; RBBP2; RBP2
IUUC-Hsa-046706
ENSG00000006459.10
Q6ZMT4
KDM7A; JHDM1D; KDM7; KIAA1718
IUUC-Hsa-046225
ENSG00000101191.16
Q9BTC0
DIDO1; C20orf158; DATF1; KIAA0333
IUUC-Hsa-046655
ENSG00000138785.14
Q96CB8
INTS12; PHF22; SBBI22
IUUC-Hsa-046560
ENSG00000198604.10
Q9NRL2
BAZ1A; ACF1; WCRF180; HSPC317
IUUC-Hsa-045916
ENSG00000170004.16
Q12873-3
CHD3
IUUC-Hsa-046737
ENSG00000126012.11
P41229
KDM5C; DXS1272E; JARID1C; SMCX; XE169
IUUC-Hsa-045967
ENSG00000112511.17
E9PQZ5
PHF1
IUUC-Hsa-045895
ENSG00000143033.17
Q9Y483
MTF2; PCL2
IUUC-Hsa-045888
ENSG00000117139.16
Q9UGL1-2
KDM5B; JARID1B; PLU1; RBBP2H1
IUUC-Hsa-046760
ENSG00000197724.10
O75151
PHF2; CENP-35; KIAA0662
IUUC-Hsa-045724
ENSG00000172943.19
Q9UPP1
PHF8; KIAA1111; ZNF422
IUUC-Hsa-046404
ENSG00000011332.19
Q92782-2
DPF1; BAF45B; NEUD4
IUUC-Hsa-047012
ENSG00000165632.7
Q5VWG9
TAF3
IUUC-Hsa-046773
ENSG00000009954.10
Q9UIG0
BAZ1B; WBSC10; WBSCR10; WBSCR9; WSTF
IUUC-Hsa-047029
ENSG00000130024.14
Q8WUB8
PHF10; BAF45A
IUUC-Hsa-046878
ENSG00000171634.16
Q12830
BPTF; FAC1; FALZ
IUUC-Hsa-046080
ENSG00000147548.16
Q9BZ95
WHSC1L1; NSD3; DC28
IUUC-Hsa-046035
ENSG00000071243.15
Q9NXR8
ING3; HSPC301
IUUC-Hsa-045965
ENSG00000168395.15
Q8WYH8
ING5
IUUC-Hsa-045837
ENSG00000168556.6
Q9H160
ING2; ING1L
IUUC-Hsa-046567
ENSG00000167548.14
O14686
KMT2D; ALR; MLL2; MLL4
IUUC-Hsa-046832
ENSG00000083168.9
Q92794
KAT6A; MOZ; MYST3; RUNXBP2; ZNF220
IUUC-Hsa-046181
ENSG00000116254.17
Q8TDI0
CHD5; KIAA0444
IUUC-Hsa-046595
ENSG00000055609.17
Q8NEZ4
KMT2C; HALR; KIAA1506; MLL3
IUUC-Hsa-046318
ENSG00000133884.9
J3KMZ8
DPF2