iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Procavia capensis E3 adaptor/Cullin RING/DCX/DWD

※ E3 adaptor/Cullin RING/DCX/DWD family introduction

DWD represents "DDB1-binding WD40 protein", a 16-residue motif as the subdomain of WD40 repeats (1). Members of DWD family can directly bind to the DDB1 and serve as the substrate recognition subunits of the DCX (DDB1-CUL4-X-box) E3 ligase complex, which display important functions in eukaryotic biology and in human diseases (2).

1. Jackson, S. and Xiong, Y. (2009). CRL4s: the CUL4-RING E3 ubiquitin ligases. Trends Biochem. Sci., 34, 562-570. PMID: 19818632

2. Angers, S., Li, T., Yi, X., MacCoss, M.J., Moon, R.T. and Zheng, N. (2006). Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature, 443, 590-593. PMID: 16964240

There are 216 genes. Reviewed (0)

or Unreviewed (216)

Download the gene list

iUUCD ID	Ensemble Gene ID	Gene Name
IUUC-Pca-100882	ENSPCAG00000018898.1	PPP2R2A
IUUC-Pca-100902	ENSPCAG00000017061.1	FBXW8
IUUC-Pca-100827	ENSPCAG00000017027.1	DYNC1I1
IUUC-Pca-101062	ENSPCAG00000016988.1	CDC20
IUUC-Pca-100173	ENSPCAG00000016945.1	WDR6
IUUC-Pca-101070	ENSPCAG00000016696.1	EML2
IUUC-Pca-100383	ENSPCAG00000016713.1	WDR74
IUUC-Pca-100980	ENSPCAG00000016719.1	WDR54
IUUC-Pca-100865	ENSPCAG00000016523.1	WDR24
IUUC-Pca-100416	ENSPCAG00000016484.1	NSMAF
IUUC-Pca-100757	ENSPCAG00000016431.1	GNB3
IUUC-Pca-100325	ENSPCAG00000016300.1	MIOS
IUUC-Pca-100950	ENSPCAG00000016187.1	WDR7
IUUC-Pca-100172	ENSPCAG00000015964.1	WDR90
IUUC-Pca-100769	ENSPCAG00000016136.1	THOC3
IUUC-Pca-100350	ENSPCAG00000016061.1	DNAI1
IUUC-Pca-100296	ENSPCAG00000016018.2	WDR92
IUUC-Pca-100803	ENSPCAG00000016073.1	DDB2
IUUC-Pca-100305	ENSPCAG00000015939.1
IUUC-Pca-100454	ENSPCAG00000016077.1	WSB2
IUUC-Pca-101097	ENSPCAG00000015799.1	WDR36
IUUC-Pca-100731	ENSPCAG00000015905.1
IUUC-Pca-100139	ENSPCAG00000015794.1	FBXW11
IUUC-Pca-100942	ENSPCAG00000015662.1
IUUC-Pca-101008	ENSPCAG00000015549.1	DMXL1
IUUC-Pca-100797	ENSPCAG00000015686.1	TSSC1
IUUC-Pca-100635	ENSPCAG00000015660.1	WDR82
IUUC-Pca-101061	ENSPCAG00000015399.1	KIF21A
IUUC-Pca-100221	ENSPCAG00000015362.1	EML3
IUUC-Pca-100527	ENSPCAG00000015432.1	WDR25
IUUC-Pca-101119	ENSPCAG00000015404.1	THOC6
IUUC-Pca-101111	ENSPCAG00000015243.1	STXBP5L
IUUC-Pca-100401	ENSPCAG00000015263.1	DCAF12
IUUC-Pca-100969	ENSPCAG00000015272.1
IUUC-Pca-100862	ENSPCAG00000015147.1	SCAP
IUUC-Pca-100153	ENSPCAG00000015111.1
IUUC-Pca-100456	ENSPCAG00000014987.1	PPWD1
IUUC-Pca-100983	ENSPCAG00000014855.1	ELP2
IUUC-Pca-101049	ENSPCAG00000014854.1	FBXW9
IUUC-Pca-100538	ENSPCAG00000014813.1	WDR83
IUUC-Pca-100809	ENSPCAG00000014631.1	NWD1
IUUC-Pca-100247	ENSPCAG00000014568.1
IUUC-Pca-100419	ENSPCAG00000014208.1	DMXL2
IUUC-Pca-100146	ENSPCAG00000014065.1	WDFY3
IUUC-Pca-100366	ENSPCAG00000014318.1	GNB1L
IUUC-Pca-100605	ENSPCAG00000013978.1	STXBP5
IUUC-Pca-100981	ENSPCAG00000013811.1	WDR38
IUUC-Pca-100753	ENSPCAG00000013665.1	WDR4
IUUC-Pca-100955	ENSPCAG00000013633.1
IUUC-Pca-100281	ENSPCAG00000013476.1	WDR5B
IUUC-Pca-100959	ENSPCAG00000013275.1	MAPKBP1
IUUC-Pca-100727	ENSPCAG00000013401.1	TAF5L
IUUC-Pca-100580	ENSPCAG00000013347.1	ARPC1B
IUUC-Pca-100626	ENSPCAG00000013205.1	CORO2A
IUUC-Pca-100896	ENSPCAG00000013084.1	MED16
IUUC-Pca-100465	ENSPCAG00000012735.1	HERC1
IUUC-Pca-100233	ENSPCAG00000012964.1	IFT122
IUUC-Pca-100593	ENSPCAG00000012899.1	DTL
IUUC-Pca-100444	ENSPCAG00000012880.1	UTP15
IUUC-Pca-101130	ENSPCAG00000012799.1	WRAP53
IUUC-Pca-100269	ENSPCAG00000012557.1
IUUC-Pca-100565	ENSPCAG00000012385.1	FZR1
IUUC-Pca-100583	ENSPCAG00000012324.1	SMU1
IUUC-Pca-100754	ENSPCAG00000012239.1	PEX7
IUUC-Pca-100761	ENSPCAG00000011961.1	STRAP
IUUC-Pca-100357	ENSPCAG00000011816.1	KATNB1
IUUC-Pca-100941	ENSPCAG00000011610.1	WDR43
IUUC-Pca-100909	ENSPCAG00000011633.1	PLRG1
IUUC-Pca-100616	ENSPCAG00000011406.1	DCAF1
IUUC-Pca-100804	ENSPCAG00000011556.1	TAF5
IUUC-Pca-100159	ENSPCAG00000011360.1	WDR44
IUUC-Pca-100120	ENSPCAG00000011289.1	PAFAH1B1
IUUC-Pca-100256	ENSPCAG00000011163.1	TBL1XR1
IUUC-Pca-100177	ENSPCAG00000010999.1
IUUC-Pca-100642	ENSPCAG00000011030.1	RBBP4
IUUC-Pca-100513	ENSPCAG00000011038.1	WDR77
IUUC-Pca-100965	ENSPCAG00000010887.1	COPB2
IUUC-Pca-100866	ENSPCAG00000010508.1	WDR75
IUUC-Pca-100826	ENSPCAG00000010258.1	SEC31A
IUUC-Pca-101002	ENSPCAG00000009855.1	TEP1
IUUC-Pca-100451	ENSPCAG00000010109.1	WDR53
IUUC-Pca-100650	ENSPCAG00000010027.1	WDFY2
IUUC-Pca-100638	ENSPCAG00000009954.1	RAE1
IUUC-Pca-100653	ENSPCAG00000009892.1	PWP1
IUUC-Pca-100680	ENSPCAG00000009753.1	ATG16L1
IUUC-Pca-100824	ENSPCAG00000009782.1	SEC13
IUUC-Pca-100904	ENSPCAG00000009728.1	WDR91
IUUC-Pca-100107	ENSPCAG00000009494.1	EML5
IUUC-Pca-100317	ENSPCAG00000009316.1	RRP9
IUUC-Pca-100560	ENSPCAG00000009272.1	AHI1
IUUC-Pca-100248	ENSPCAG00000009327.1	WDR13
IUUC-Pca-100404	ENSPCAG00000009271.1	DCAF7
IUUC-Pca-100155	ENSPCAG00000009114.1	DCAF6
IUUC-Pca-100846	ENSPCAG00000009080.1	RFWD2
IUUC-Pca-100217	ENSPCAG00000009039.1	NEDD1
IUUC-Pca-100567	ENSPCAG00000008889.1	WDR41
IUUC-Pca-100577	ENSPCAG00000008906.1	WDR34
IUUC-Pca-101035	ENSPCAG00000008783.1	AMBRA1
IUUC-Pca-101137	ENSPCAG00000008745.1	TLE4
IUUC-Pca-100988	ENSPCAG00000008681.1	GNB5
IUUC-Pca-100411	ENSPCAG00000008674.1	CORO1B
IUUC-Pca-100957	ENSPCAG00000008587.1	GEMIN5
IUUC-Pca-100464	ENSPCAG00000008598.1	WDR49
IUUC-Pca-101048	ENSPCAG00000008482.1	CIAO1
IUUC-Pca-101047	ENSPCAG00000008359.1	STRN3
IUUC-Pca-100523	ENSPCAG00000008259.1	WDSUB1
IUUC-Pca-100871	ENSPCAG00000008247.1	SNRNP40
IUUC-Pca-101034	ENSPCAG00000008214.1	WSB1
IUUC-Pca-100968	ENSPCAG00000008243.1	WDR89
IUUC-Pca-100351	ENSPCAG00000008027.1	WDR70
IUUC-Pca-100394	ENSPCAG00000007979.1	WDR12
IUUC-Pca-100520	ENSPCAG00000007835.1
IUUC-Pca-100741	ENSPCAG00000007836.1	WDFY1
IUUC-Pca-100558	ENSPCAG00000007722.1	HIRA
IUUC-Pca-100989	ENSPCAG00000007704.1	WDHD1
IUUC-Pca-100326	ENSPCAG00000007736.1	BUB3
IUUC-Pca-100187	ENSPCAG00000007685.1	ERCC8
IUUC-Pca-100365	ENSPCAG00000007620.1	DCAF13
IUUC-Pca-100384	ENSPCAG00000007648.1	DAW1
IUUC-Pca-100867	ENSPCAG00000007632.1
IUUC-Pca-101095	ENSPCAG00000007569.1	WDTC1
IUUC-Pca-100313	ENSPCAG00000007531.1	GNB1
IUUC-Pca-100571	ENSPCAG00000007416.1	FBXW7
IUUC-Pca-100820	ENSPCAG00000007329.1	ZNF106
IUUC-Pca-100203	ENSPCAG00000007357.1	PPP2R2D
IUUC-Pca-100682	ENSPCAG00000007210.1	NLE1
IUUC-Pca-100321	ENSPCAG00000007116.1	TLE3
IUUC-Pca-100413	ENSPCAG00000007046.1	COPA
IUUC-Pca-101053	ENSPCAG00000007041.1	PAK1IP1
IUUC-Pca-100729	ENSPCAG00000006950.1
IUUC-Pca-100405	ENSPCAG00000006840.1	WDR33
IUUC-Pca-100333	ENSPCAG00000006873.1	BOP1
IUUC-Pca-100926	ENSPCAG00000006739.1	CORO6
IUUC-Pca-101057	ENSPCAG00000006673.1	NUP37
IUUC-Pca-100940	ENSPCAG00000006526.1	GNB2
IUUC-Pca-100746	ENSPCAG00000006381.1	STRN4
IUUC-Pca-100999	ENSPCAG00000006391.1	DCAF5
IUUC-Pca-100322	ENSPCAG00000006338.1	SEH1L
IUUC-Pca-100562	ENSPCAG00000006251.1	UTP4
IUUC-Pca-100288	ENSPCAG00000006258.1	PREB
IUUC-Pca-100386	ENSPCAG00000005865.1	NBEAL2
IUUC-Pca-100759	ENSPCAG00000005846.1	BRWD1
IUUC-Pca-101089	ENSPCAG00000006107.1	FBXW2
IUUC-Pca-100752	ENSPCAG00000006069.1	WDR88
IUUC-Pca-100845	ENSPCAG00000006051.1
IUUC-Pca-100852	ENSPCAG00000006046.1	WDR37
IUUC-Pca-100778	ENSPCAG00000005560.1	APAF1
IUUC-Pca-100429	ENSPCAG00000005329.1	LYST
IUUC-Pca-100937	ENSPCAG00000005519.1	WDR11
IUUC-Pca-100623	ENSPCAG00000005452.1	RBBP5
IUUC-Pca-101019	ENSPCAG00000005356.1	TBL2
IUUC-Pca-100763	ENSPCAG00000005178.1	WDR59
IUUC-Pca-100171	ENSPCAG00000005172.1	SPAG16
IUUC-Pca-100972	ENSPCAG00000005012.1	WDR18
IUUC-Pca-100259	ENSPCAG00000005070.1	DMWD
IUUC-Pca-100664	ENSPCAG00000005049.1	WDR61
IUUC-Pca-100713	ENSPCAG00000004946.1	RFWD3
IUUC-Pca-100888	ENSPCAG00000004870.1	FBXW4
IUUC-Pca-101014	ENSPCAG00000004805.1	EIF3I
IUUC-Pca-100268	ENSPCAG00000004849.1	CSTF1
IUUC-Pca-100250	ENSPCAG00000004780.1	RBBP7
IUUC-Pca-100947	ENSPCAG00000004676.1
IUUC-Pca-100843	ENSPCAG00000004714.1	BTRC
IUUC-Pca-101025	ENSPCAG00000004653.1	WDR76
IUUC-Pca-100266	ENSPCAG00000004492.1	STRN
IUUC-Pca-100847	ENSPCAG00000004215.1	SHKBP1
IUUC-Pca-100971	ENSPCAG00000004232.1	MLST8
IUUC-Pca-100375	ENSPCAG00000003977.1	TRAF7
IUUC-Pca-100876	ENSPCAG00000003968.1	CDC40
IUUC-Pca-100381	ENSPCAG00000003985.1	PAAF1
IUUC-Pca-101072	ENSPCAG00000003858.1	AAMP
IUUC-Pca-100831	ENSPCAG00000003721.1	WDR63
IUUC-Pca-100733	ENSPCAG00000003589.1
IUUC-Pca-100964	ENSPCAG00000003537.1	DNAI2
IUUC-Pca-101128	ENSPCAG00000003391.1	PHIP
IUUC-Pca-100630	ENSPCAG00000003469.1	CORO1C
IUUC-Pca-100236	ENSPCAG00000003390.1	TLE2
IUUC-Pca-100323	ENSPCAG00000003218.1	WDR62
IUUC-Pca-100343	ENSPCAG00000003335.1	GNB4
IUUC-Pca-100572	ENSPCAG00000003310.1	CORO1A
IUUC-Pca-100455	ENSPCAG00000003303.1	NUP43
IUUC-Pca-100403	ENSPCAG00000003327.1
IUUC-Pca-100225	ENSPCAG00000003164.1	EML4
IUUC-Pca-101023	ENSPCAG00000003193.1	LRWD1
IUUC-Pca-100599	ENSPCAG00000003072.1	PLAA
IUUC-Pca-100287	ENSPCAG00000003094.1
IUUC-Pca-100574	ENSPCAG00000002979.1	WDR26
IUUC-Pca-100220	ENSPCAG00000002794.1	ATG16L2
IUUC-Pca-100863	ENSPCAG00000002706.1	WDR64
IUUC-Pca-100819	ENSPCAG00000002608.1	TBL1X
IUUC-Pca-100192	ENSPCAG00000002621.1	WDR31
IUUC-Pca-100152	ENSPCAG00000002561.1	PRPF4
IUUC-Pca-101100	ENSPCAG00000002445.1	WDR47
IUUC-Pca-100176	ENSPCAG00000002394.1	WDR45
IUUC-Pca-100232	ENSPCAG00000002157.1	TBL3
IUUC-Pca-101012	ENSPCAG00000002158.1	POC1B
IUUC-Pca-101122	ENSPCAG00000002118.1	POC1A
IUUC-Pca-101037	ENSPCAG00000002037.1	CFAP52
IUUC-Pca-100553	ENSPCAG00000001930.1	PRPF19
IUUC-Pca-100440	ENSPCAG00000001800.1	WDR17
IUUC-Pca-100720	ENSPCAG00000001782.1	WDR27
IUUC-Pca-100377	ENSPCAG00000001637.1	PIK3R4
IUUC-Pca-100606	ENSPCAG00000001421.1	SEC31B
IUUC-Pca-100133	ENSPCAG00000001445.1	CORO2B
IUUC-Pca-100408	ENSPCAG00000001427.1	WDR55
IUUC-Pca-100796	ENSPCAG00000001265.1	WDR3
IUUC-Pca-100163	ENSPCAG00000001331.1	FBXW5
IUUC-Pca-100240	ENSPCAG00000001086.1	LRBA
IUUC-Pca-101136	ENSPCAG00000001018.1
IUUC-Pca-100675	ENSPCAG00000000967.1	TLE1
IUUC-Pca-100777	ENSPCAG00000000965.1	DCAF10
IUUC-Pca-100257	ENSPCAG00000000754.1	WDR1
IUUC-Pca-100594	ENSPCAG00000000697.1	RACK1
IUUC-Pca-100255	ENSPCAG00000000647.1	GTF3C2
IUUC-Pca-100458	ENSPCAG00000000589.1	WDR48
IUUC-Pca-100781	ENSPCAG00000000061.1	KIF21B