Homo sapiens         E3 adaptor/Cullin RING/ECS/Elon-B_C


※ E3 adaptor/Cullin RING/ECS/Elon-B_C family introduction

    Elon-B/C is a complex that comprises two subunits, named Elongin B and Elongin C. In the BCR ubiquitin ligase complex, a member of Elon-B/C family acts as an adaptor binding a substrate recognition subunit to heterodimer composed of either Cul2-Rbx1 or Cul5-Rbx2.

1. Piessevaux, J., De Ceuninck, L., Catteeuw, D., Peelman, F. & Tavernier, J. (2004). Elongin B/C recruitment regulates substrate binding by CIS. J. Biol. Chem.., 283(31): 21334-46. PMID: 15601820




There are 2 genes.  Reviewed (2 or Unreviewed (0Download the gene list
StatusiUUCD IDEnsemble Gene IDUniProt AccessionGene Name
IUUC-Hsa-046045
ENSG00000154582.16
Q15369
TCEB1; ELOC
IUUC-Hsa-046790
ENSG00000103363.14
Q15370
TCEB2; ELOB