Homo sapiens E3 adaptor/Cullin RING/SCF/SKP1
※ E3 adaptor/Cullin RING/SCF/SKP1 family introduction
SKP1 is a structurally multi-helical domain found at the C-terminal of SKP1 proteins, as well as in subunit D of the centromere DNA-binding protein complex Cbf3. This domain consists of an interlocked herterodimer in F-box proteins. SKP1 (together with SKP2) was identified as an essential component of the cyclin A-CDK2 S phase kinase complex. Now it is thought as a adaptor that connects cullin1 and F-box containing protein and involves in the ubiquitin pathway (1).
There are 1 genes. Reviewed (0)  or Unreviewed (1)  | Download the gene list |
| Status | iUUCD ID | Ensemble Gene ID | UniProt Accession | Gene Name |
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