Pongo abelii         E3 adaptor/Cullin RING/SCF/SKP1


※ E3 adaptor/Cullin RING/SCF/SKP1 family introduction

    SKP1 is a structurally multi-helical domain found at the C-terminal of SKP1 proteins, as well as in subunit D of the centromere DNA-binding protein complex Cbf3. This domain consists of an interlocked herterodimer in F-box proteins. SKP1 (together with SKP2) was identified as an essential component of the cyclin A-CDK2 S phase kinase complex. Now it is thought as a adaptor that connects cullin1 and F-box containing protein and involves in the ubiquitin pathway (1).

1. http://pfam.xfam.org/family/Skp1




There are 2 genes.  Reviewed (0 or Unreviewed (2Download the gene list
StatusiUUCD IDEnsemble Gene IDUniProt AccessionGene Name
IUUC-Pab-098008
ENSPPYG00000019927.1
H2PUD3
IUUC-Pab-098533
ENSPPYG00000015783.1
Q5R512
SKP1; SKP1A