PTM - CPLM Gene Name UniProt ID Type Position Code NEDD8 Q15843 Acetylation 48 K NEDD8 Q15843 Ubiquitination 11 K NEDD8 Q15843 Ubiquitination 48 K NEDD8 Q15843 Ubiquitination 54 K NEDD8 Q15843 Ubiquitination 60 K NEDD8 Q15843 Ubiquitination 27 K NEDD8 Q15843 Ubiquitination 33 K NEDD8 Q15843 Ubiquitination 6 K NEDD8 Q15843 Ubiquitination 22 K NEDD8 Q15843 Ubiquitination 4 K

PTM - dbPAF Gene Name UniProt ID Position Type Species NEDD8 Q15843 20 T Homo sapiens(Human) NEDD8 Q15843 45 Y Homo sapiens(Human) NEDD8 Q15843 46 S Homo sapiens(Human) NEDD8 Q15843 59 Y Homo sapiens(Human) NEDD8 Q15843 65 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q15843 K11-ac Acetylation kVktLtGkEIEIDIE Q15843 K48-ac Acetylation QRLIysGkQMNDEkT Q15843 K54-ac Acetylation GkQMNDEkTAADykI Q15843 T7-p Phosphorylation _MLIkVktLtGkEIE Q15843 T9-p Phosphorylation LIkVktLtGkEIEID Q15843 T20-p Phosphorylation IEIDIEPtDkVERIk Q15843 Y45-p Phosphorylation PQQQRLIysGkQMND Q15843 S46-p Phosphorylation QQQRLIysGkQMNDE Q15843 Y59-p Phosphorylation DEkTAADykILGGsV Q15843 S65-p Phosphorylation DykILGGsVLHLVLA Q15843 K48-sm Sumoylation QRLIysGkQMNDEkT Q15843 K4-ub Ubiquitination ____MLIkVktLtGk Q15843 K6-ub Ubiquitination __MLIkVktLtGkEI Q15843 K11-ub Ubiquitination kVktLtGkEIEIDIE Q15843 K22-ub Ubiquitination IDIEPtDkVERIkER Q15843 K27-ub Ubiquitination tDkVERIkERVEEkE Q15843 K33-ub Ubiquitination IkERVEEkEGIPPQQ Q15843 K48-ub Ubiquitination QRLIysGkQMNDEkT Q15843 K54-ub Ubiquitination GkQMNDEkTAADykI Q15843 K60-ub Ubiquitination EkTAADykILGGsVL

PTM - dbPTM UniProt ID Position Code Type Resources References Q15843 48 K Acetylation Swiss-Prot 1010711 19608861 Q15843 76 G Isopeptide bond Swiss-Prot 1010711 - Q15843 11 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q15843 22 K Ubiquitylation Phosphositeplus.1010730 21906983 Q15843 27 K Ubiquitylation Phosphositeplus.1010730 21906983 Q15843 33 K Ubiquitylation Phosphositeplus.1010730 21906983 Q15843 48 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q15843 54 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q15843 6 K Ubiquitylation Phosphositeplus.1010730 21906983 Q15843 60 K Ubiquitylation Phosphositeplus.1010730 19782077;21906983 Q15843 48 K Acetylation Phosphositeplus.1010730 19608861 Q15843 11 K Neddylation Phosphositeplus.1010730 18247557 Q15843 22 K Neddylation Phosphositeplus.1010730 18247557 Q15843 48 K Neddylation Phosphositeplus.1010730 18247557 Q15843 60 K Neddylation Phosphositeplus.1010730 18247557 Q15843 20 T Phosphorylation Phosphositeplus.1010730 21406692 Q15843 59 Y Phosphorylation Phosphositeplus.1010730 18083107 Q15843 48 K Acetylation HPRD 9.0 19608861

PTM - HPRD Symbol Position Code Type References NEDD8 48 K Acetylation 19608861

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type NEDD8 IPI00020008 K 48 RLIYSGaKQMNDEK acetylation NEDD8 IPI00020008 S 65 YKILGGpSVLHLVL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 4738 110815 - K Neddylation 18274552 4738 110815 - K Ubiquitination 21987572 4738 110815 - K Sumoylation 21693764 4738 110815 - K Ubiquitination 21963094 4738 110815 - K Ubiquitination 21139048 4738 110815 - K Ubiquitination 21890473 4738 110815 - K Ubiquitination 21906983 4738 110815 - K Sumoylation 19471022 4738 110815 - K Sumoylation 21252943 4738 110815 - K Ubiquitination 22584050 4738 110815 - K Ubiquitination 22370482 4738 110815 - K Ubiquitination 22505724 4738 110815 - K Ubiquitination 23000965 4738 110815 - K Ubiquitination 24654937 4738 110815 - K Neddylation 24654937 4738 110815 - K Sumoylation 24654937 4738 110815 - K Ubiquitination 24816145 4738 110815 - K Ubiquitination 25015289 4738 110815 - K Ubiquitination 25147182 4738 110815 - K Neddylation 20029837 4738 110815 - K Neddylation 22370482 4738 110815 - K Neddylation 18247557

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID NEDD8 Homo sapiens (Human) 53; 47 "53,KQMNDEKTAADYK; 47,RLIYSGKQMNDEK" 53:21890473; 47:21890473 NEDD8 Homo sapiens (Human) 33; 48; 54; 6; 22; 27; 11; 60 "33,KERVEEKEGIPPQ; 48,RLIYSGKQMNDEK; 54,KQMNDEKTAADYK; 6,MLIKVKTLTGKE; 22,DIEPTDKVERIKE; 27,DKVERIKERVEEK; 11,VKTLTGKEIEIDI; 60,KTAADYKILGGSV" "33:21906983; 48:21890473,21906983; 54:21890473,21906983; 6:21906983; 22:21906983; 27:21906983; 11:21890473,21906983; 60:21906983"