PTM - CPLM Gene Name UniProt ID Type Position Code MKRN1; RNF61 Q9UHC7 Ubiquitination 113 K MKRN1; RNF61 Q9UHC7 Ubiquitination 321 K MKRN1; RNF61 Q9UHC7 Ubiquitination 211 K MKRN1; RNF61 Q9UHC7 Ubiquitination 70 K MKRN1; RNF61 Q9UHC7 Ubiquitination 389 K MKRN1; RNF61 Q9UHC7 Ubiquitination 354 K MKRN1; RNF61 Q9UHC7 Ubiquitination 326 K MKRN1; RNF61 Q9UHC7 Ubiquitination 265 K MKRN1; RNF61 Q9UHC7 Ubiquitination 277 K MKRN1; RNF61 Q9UHC7 Ubiquitination 110 K MKRN1; RNF61 Q9UHC7 Ubiquitination 368 K MKRN1; RNF61 Q9UHC7 Ubiquitination 202 K MKRN1; RNF61 Q9UHC7 Ubiquitination 351 K MKRN1; RNF61 Q9UHC7 Ubiquitination 210 K MKRN1; RNF61 Q9UHC7 Ubiquitination 257 K

PTM - dbPAF Gene Name UniProt ID Position Type Species MKRN1; RNF61 Q9UHC7 309 Y Homo sapiens(Human) MKRN1; RNF61 Q9UHC7 379 S Homo sapiens(Human) MKRN1; RNF61 Q9UHC7 392 Y Homo sapiens(Human) MKRN1; RNF61 Q9UHC7 409 S Homo sapiens(Human) MKRN1; RNF61 Q9UHC7 411 Y Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type MKRN1; RNF61 rs1062769 TAC->TTC Y->F 309 Y LSNCNHTYCLKCIRK 309 Phosphorylation TypeI-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9UHC7 K360-ac Acetylation EkQKLILkYKEAMSN Q9UHC7 R95-m1 Methylation VVCKYFQrGYCIYGD Q9UHC7 T123-p Phosphorylation EATATELtTKSSLAA Q9UHC7 S132-p Phosphorylation KSSLAASsSLSSIVG Q9UHC7 S194-p Phosphorylation TEAPLQGsVTKEESE Q9UHC7 Y309-p Phosphorylation LSNCNHTyCLKCIRK Q9UHC7 S379-p Phosphorylation YFDEGRGsCPFGGNC Q9UHC7 S409-p Phosphorylation RQKVGTSsRyRAQRR Q9UHC7 Y411-p Phosphorylation KVGTSsRyRAQRRNH Q9UHC7 K113-ub Ubiquitination YEHSKPLkQEEATAT Q9UHC7 K202-ub Ubiquitination VTKEESEkEQTAVET Q9UHC7 K210-ub Ubiquitination EQTAVETkkQLCPYA Q9UHC7 K211-ub Ubiquitination QTAVETkkQLCPYAA Q9UHC7 K265-ub Ubiquitination SCIEAHEkDMELSFA Q9UHC7 K277-ub Ubiquitination SFAVQRSkDMVCGIC Q9UHC7 K321-ub Ubiquitination IRKWRSAkQFESkII Q9UHC7 K326-ub Ubiquitination SAkQFESkIIKSCPE Q9UHC7 K351-ub Ubiquitination SEYWVEEkEEkQKLI Q9UHC7 K354-ub Ubiquitination WVEEkEEkQKLILkY Q9UHC7 K389-ub Ubiquitination FGGNCFYkHAYPDGR

PTM - dbPTM UniProt ID Position Code Type Resources References Q9UHC7 113 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9UHC7 202 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9UHC7 321 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9UHC7 351 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9UHC7 392 Y Phosphorylation Phosphositeplus.1010730 18083107

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 23608 117141 - K Ubiquitination 21139048 23608 117141 - K Ubiquitination 21890473 23608 117141 - K Ubiquitination 21906983 23608 117141 - K Ubiquitination 22505724 23608 117141 - K Ubiquitination 22864571 23608 117141 - K Ubiquitination 21963094

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID MKRN1 Homo sapiens (Human) 49; 257 "49,EHSKPLKQEEATA; 257,RKWRSAKQFESKI" 49:21890473; 257:21890473 MKRN1 Homo sapiens (Human) 113; 321 "113,EHSKPLKQEEATA; 321,RKWRSAKQFESKI" 113:21890473; 321:21890473 MKRN1 Homo sapiens (Human) 113; 321 "113,EHSKPLKQEEATA; 321,RKWRSAKQFESKI" 113:21890473; 321:21890473 MKRN1 Homo sapiens (Human) 49 "49,EHSKPLKQEEATA" 49:21890473 MKRN1 Homo sapiens (Human) 113; 321 "113,EHSKPLKQEEATA; 321,RKWRSAKQFESKI" 113:21890473; 321:21890473 MKRN1 Homo sapiens (Human) 113; 321 "113,EHSKPLKQEEATA; 321,RKWRSAKQFESKI" 113:21890473; 321:21890473 MKRN1 Homo sapiens (Human) 110; 318 "110,EHSKPLKQEEATA; 318,RKWRSAKQFESKI" 110:21890473; 318:21890473 MKRN1 Homo sapiens (Human) 49 "49,EHSKPLKQEEATA" 49:21890473 MKRN1 Homo sapiens (Human) 64 "64,EHSKPLKQEEATA" 64:21890473 MKRN1 Homo sapiens (Human) 113; 321 "113,EHSKPLKQEEATA; 321,RKWRSAKQFESKI" 113:21890473; 321:21890473 MKRN1 Homo sapiens (Human) 113; 202; 321; 351 "113,EHSKPLKQEEATA; 202,TKEESEKEQTAVE; 321,RKWRSAKQFESKI; 351,EYWVEEKEEKQKL" "113:21890473; 202:21906983; 321:21890473,21906983; 351:21906983" MKRN1 Homo sapiens (Human) 49 "49,EHSKPLKQEEATA" 49:21890473