Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 11 102935066 102935066 + Missense_Mutation SNP T T C TCGA-XF-A9T0-01A-11D-A391-08 TCGA-XF-A9T0-10A-01D-A394-08 g.chr11:102935066T>C c.596A>G c.(595-597)aAt>aGt p.N199S BLCA 11 102937215 102937215 + Silent SNP G G A TCGA-XF-A9T8-01A-11D-A391-08 TCGA-XF-A9T8-10A-01D-A394-08 g.chr11:102937215G>A c.423C>T c.(421-423)atC>atT p.I141I BLCA 11 102962543 102962543 + Missense_Mutation SNP C C G TCGA-SY-A9G5-01A-11D-A38G-08 TCGA-SY-A9G5-10A-01D-A38J-08 g.chr11:102962543C>G c.59G>C c.(58-60)gGa>gCa p.G20A BRCA 11 102935019 102935019 + Missense_Mutation SNP C C T TCGA-E2-A1IN-01A-11D-A13L-09 TCGA-E2-A1IN-10A-01D-A188-09 g.chr11:102935019C>T c.643G>A c.(643-645)Gat>Aat p.D215N CESC 11 102954050 102954050 + Missense_Mutation SNP C C T TCGA-EK-A3GK-01A-11D-A20U-09 TCGA-EK-A3GK-10A-01D-A20U-09 g.chr11:102954050C>T c.184G>A c.(184-186)Gat>Aat p.D62N COAD 11 102937290 102937290 + Silent SNP G G A TCGA-CK-5914-01A-11D-1650-10 TCGA-CK-5914-10A-01D-1650-10 g.chr11:102937290G>A c.348C>T c.(346-348)gaC>gaT p.D116D COADREAD 11 102937290 102937290 + Silent SNP G G A TCGA-CK-5914-01A-11D-1650-10 TCGA-CK-5914-10A-01D-1650-10 g.chr11:102937290G>A c.348C>T c.(346-348)gaC>gaT p.D116D ESCA 11 102935036 102935036 + Missense_Mutation SNP G G A TCGA-L5-A4OI-01A-11D-A27G-09 TCGA-L5-A4OI-11A-11D-A27G-09 g.chr11:102935036G>A c.626C>T c.(625-627)gCt>gTt p.A209V ESCA 11 102937291 102937291 + Missense_Mutation SNP T T G TCGA-JY-A938-01A-11D-A37C-09 TCGA-JY-A938-10A-01D-A37F-09 g.chr11:102937291T>G c.347A>C c.(346-348)gAc>gCc p.D116A GBMLGG 11 102937048 102937048 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr11:102937048G>T c.505C>A c.(505-507)Ctg>Atg p.L169M GBMLGG 11 102937266 102937266 + Silent SNP T T C TCGA-KT-A7W1-01A-11D-A34A-08 TCGA-KT-A7W1-10A-01D-A34A-08 g.chr11:102937266T>C c.372A>G c.(370-372)aaA>aaG p.K124K HNSC 11 102954040 102954040 + Missense_Mutation SNP A A C TCGA-P3-A5QA-01A-11D-A28R-08 TCGA-P3-A5QA-10A-01D-A28U-08 g.chr11:102954040A>C c.194T>G c.(193-195)gTa>gGa p.V65G LGG 11 102937048 102937048 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr11:102937048G>T c.505C>A c.(505-507)Ctg>Atg p.L169M LGG 11 102937266 102937266 + Silent SNP T T C TCGA-KT-A7W1-01A-11D-A34A-08 TCGA-KT-A7W1-10A-01D-A34A-08 g.chr11:102937266T>C c.372A>G c.(370-372)aaA>aaG p.K124K LIHC 11 102935046 102935046 + Missense_Mutation SNP T T A TCGA-DD-AAC9-01A-11D-A40R-10 TCGA-DD-AAC9-10A-01D-A40U-10 g.chr11:102935046T>A c.616A>T c.(616-618)Aca>Tca p.T206S LIHC 11 102937078 102937078 + Missense_Mutation SNP T T C TCGA-DD-AADE-01A-11D-A40R-10 TCGA-DD-AADE-10A-01D-A40U-10 g.chr11:102937078T>C c.475A>G c.(475-477)Att>Gtt p.I159V LUAD 11 102933091 102933091 + Silent SNP T T C TCGA-55-8511-01A-11D-2393-08 TCGA-55-8511-10A-01D-2393-08 g.chr11:102933091T>C c.711A>G c.(709-711)tcA>tcG p.S237S LUAD 11 102937253 102937253 + Missense_Mutation SNP G G A TCGA-17-Z060-01A-01W-0747-08 TCGA-17-Z060-11A-01W-0747-08 g.chr11:102937253G>A c.385C>T c.(385-387)Cgc>Tgc p.R129C PAAD 11 102933112 102933112 + Nonsense_Mutation SNP C C T TCGA-FZ-5920-01A-11D-1609-08 TCGA-FZ-5920-11A-01D-1609-08 g.chr11:102933112C>T c.690G>A c.(688-690)tgG>tgA p.W230* SKCM 11 102937231 102937231 + Missense_Mutation SNP G G A TCGA-D3-A3C7-06A-11D-A196-08 TCGA-D3-A3C7-10A-01D-A198-08 g.chr11:102937231G>A c.407C>T c.(406-408)tCg>tTg p.S136L SKCM 11 102937231 102937231 + Missense_Mutation SNP G G A TCGA-EE-A2GO-06A-11D-A196-08 TCGA-EE-A2GO-10A-01D-A198-08 g.chr11:102937231G>A c.407C>T c.(406-408)tCg>tTg p.S136L

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BRCA-EU 11 102928086 102928086 single base substitution G A downstream_gene_variant BRCA-EU 11 102928974 102928974 single base substitution C A downstream_gene_variant BRCA-EU 11 102930447 102930447 single base substitution T C downstream_gene_variant BRCA-EU 11 102931595 102931595 single base substitution T C downstream_gene_variant BRCA-EU 11 102932387 102932387 single base substitution A G downstream_gene_variant BRCA-EU 11 102933025 102933025 single base substitution C A 3_prime_UTR_variant BRCA-EU 11 102933025 102933025 single base substitution C A downstream_gene_variant BRCA-EU 11 102936471 102936471 deletion of <=200bp T - downstream_gene_variant BRCA-EU 11 102936471 102936471 deletion of <=200bp T - intron_variant BRCA-EU 11 102936503 102936503 single base substitution A C downstream_gene_variant BRCA-EU 11 102936503 102936503 single base substitution A C intron_variant BRCA-EU 11 102936613 102936613 single base substitution A G downstream_gene_variant BRCA-EU 11 102936613 102936613 single base substitution A G intron_variant BRCA-EU 11 102937558 102937558 single base substitution A G intron_variant BRCA-EU 11 102937729 102937729 single base substitution T C intron_variant BRCA-EU 11 102938128 102938128 single base substitution T C intron_variant BRCA-EU 11 102939238 102939238 deletion of <=200bp A - intron_variant BRCA-EU 11 102941218 102941218 single base substitution T C intron_variant BRCA-EU 11 102942161 102942162 deletion of <=200bp CT - intron_variant BRCA-EU 11 102942791 102942791 single base substitution G T intron_variant BRCA-EU 11 102942836 102942836 single base substitution A G intron_variant BRCA-EU 11 102943312 102943312 single base substitution A G intron_variant BRCA-EU 11 102943530 102943530 single base substitution C G intron_variant BRCA-EU 11 102944821 102944821 deletion of <=200bp A - intron_variant BRCA-EU 11 102946208 102946208 single base substitution T A intron_variant BRCA-EU 11 102946649 102946649 single base substitution C A intron_variant BRCA-EU 11 102946687 102946687 single base substitution C T intron_variant BRCA-EU 11 102947243 102947243 single base substitution C G intron_variant BRCA-EU 11 102948450 102948450 single base substitution C G intron_variant BRCA-EU 11 102949341 102949341 single base substitution C G intron_variant BRCA-EU 11 102950758 102950758 single base substitution A G intron_variant BRCA-EU 11 102950934 102950934 single base substitution C T intron_variant BRCA-EU 11 102951786 102951786 single base substitution G A intron_variant BRCA-EU 11 102951823 102951823 single base substitution T C intron_variant BRCA-EU 11 102953780 102953780 single base substitution C T intron_variant BRCA-EU 11 102953780 102953780 single base substitution C T upstream_gene_variant BRCA-EU 11 102954017 102954017 single base substitution A C 3_prime_UTR_variant BRCA-EU 11 102954017 102954017 single base substitution A C exon_variant BRCA-EU 11 102954017 102954017 single base substitution A C intron_variant BRCA-EU 11 102954017 102954017 single base substitution A C missense_variant F44V 130T>G BRCA-EU 11 102954017 102954017 single base substitution A C missense_variant F73V 217T>G BRCA-EU 11 102954017 102954017 single base substitution A C upstream_gene_variant BRCA-EU 11 102954828 102954828 single base substitution T C intron_variant BRCA-EU 11 102954828 102954828 single base substitution T C upstream_gene_variant BRCA-EU 11 102954918 102954918 single base substitution T A intron_variant BRCA-EU 11 102954918 102954918 single base substitution T A upstream_gene_variant BRCA-EU 11 102956428 102956428 single base substitution C T downstream_gene_variant BRCA-EU 11 102956428 102956428 single base substitution C T intron_variant BRCA-EU 11 102956428 102956428 single base substitution C T upstream_gene_variant BRCA-EU 11 102956646 102956646 single base substitution C G downstream_gene_variant BRCA-EU 11 102956646 102956646 single base substitution C G intron_variant BRCA-EU 11 102956646 102956646 single base substitution C G upstream_gene_variant BRCA-EU 11 102958784 102958784 single base substitution A C downstream_gene_variant BRCA-EU 11 102958784 102958784 single base substitution A C intron_variant BRCA-EU 11 102963976 102963976 single base substitution T C upstream_gene_variant BRCA-EU 11 102966807 102966807 single base substitution C T upstream_gene_variant BRCA-EU 11 102966935 102966935 single base substitution G C upstream_gene_variant BRCA-EU 11 102967753 102967753 single base substitution G A upstream_gene_variant BRCA-FR 11 102928974 102928974 single base substitution C A downstream_gene_variant BRCA-FR 11 102930536 102930536 single base substitution T C downstream_gene_variant BRCA-FR 11 102942299 102942299 single base substitution T A intron_variant BRCA-FR 11 102946649 102946649 single base substitution C A intron_variant BRCA-UK 11 102932354 102932354 single base substitution C A downstream_gene_variant BRCA-UK 11 102943530 102943530 single base substitution C G intron_variant BRCA-UK 11 102955773 102955773 single base substitution G A downstream_gene_variant BRCA-UK 11 102955773 102955773 single base substitution G A intron_variant BRCA-UK 11 102955773 102955773 single base substitution G A upstream_gene_variant BRCA-UK 11 102956737 102956737 single base substitution G A downstream_gene_variant BRCA-UK 11 102956737 102956737 single base substitution G A intron_variant BRCA-UK 11 102956737 102956737 single base substitution G A upstream_gene_variant BRCA-US 11 102935019 102935019 single base substitution C T 3_prime_UTR_variant BRCA-US 11 102935019 102935019 single base substitution C T downstream_gene_variant BRCA-US 11 102935019 102935019 single base substitution C T intron_variant BRCA-US 11 102935019 102935019 single base substitution C T missense_variant D130N 388G>A BRCA-US 11 102935019 102935019 single base substitution C T missense_variant D215N 643G>A BTCA-JP 11 102934966 102934966 single base substitution A T downstream_gene_variant BTCA-JP 11 102934966 102934966 single base substitution A T intron_variant BTCA-JP 11 102936880 102936880 single base substitution A G downstream_gene_variant BTCA-JP 11 102936880 102936880 single base substitution A G intron_variant BTCA-JP 11 102936937 102936937 single base substitution A C downstream_gene_variant BTCA-JP 11 102936937 102936937 single base substitution A C intron_variant BTCA-JP 11 102960132 102960132 single base substitution C T intron_variant BTCA-JP 11 102960132 102960132 single base substitution C T upstream_gene_variant CESC-US 11 102954050 102954050 single base substitution C T 3_prime_UTR_variant CESC-US 11 102954050 102954050 single base substitution C T exon_variant CESC-US 11 102954050 102954050 single base substitution C T intron_variant CESC-US 11 102954050 102954050 single base substitution C T missense_variant D33N 97G>A CESC-US 11 102954050 102954050 single base substitution C T missense_variant D62N 184G>A CESC-US 11 102954050 102954050 single base substitution C T upstream_gene_variant CLLE-ES 11 102967007 102967007 single base substitution G C upstream_gene_variant COAD-US 11 102937290 102937290 single base substitution G A 3_prime_UTR_variant COAD-US 11 102937290 102937290 single base substitution G A synonymous_variant D116D 348C>T COAD-US 11 102937290 102937290 single base substitution G A synonymous_variant D31D 93C>T COAD-US 11 102937290 102937290 single base substitution G A synonymous_variant D87D 261C>T COCA-CN 11 102933155 102933155 single base substitution G T downstream_gene_variant COCA-CN 11 102933155 102933155 single base substitution G T intron_variant ESAD-UK 11 102930986 102930986 single base substitution G A downstream_gene_variant ESAD-UK 11 102931302 102931302 single base substitution G A downstream_gene_variant ESAD-UK 11 102932275 102932275 single base substitution T A downstream_gene_variant ESAD-UK 11 102932347 102932347 single base substitution C T downstream_gene_variant ESAD-UK 11 102934110 102934110 single base substitution C T downstream_gene_variant ESAD-UK 11 102934110 102934110 single base substitution C T intron_variant ESAD-UK 11 102936443 102936443 single base substitution A T downstream_gene_variant ESAD-UK 11 102936443 102936443 single base substitution A T intron_variant ESAD-UK 11 102936471 102936471 deletion of <=200bp T - downstream_gene_variant ESAD-UK 11 102936471 102936471 deletion of <=200bp T - intron_variant ESAD-UK 11 102936507 102936507 single base substitution T C downstream_gene_variant ESAD-UK 11 102936507 102936507 single base substitution T C intron_variant ESAD-UK 11 102937367 102937367 single base substitution A C intron_variant ESAD-UK 11 102937565 102937565 single base substitution C G intron_variant ESAD-UK 11 102938524 102938524 single base substitution G A intron_variant ESAD-UK 11 102938638 102938638 single base substitution T C intron_variant ESAD-UK 11 102945001 102945001 insertion of <=200bp - C intron_variant ESAD-UK 11 102946202 102946202 single base substitution C T intron_variant ESAD-UK 11 102949823 102949823 single base substitution G A intron_variant ESAD-UK 11 102952961 102952961 single base substitution A G intron_variant ESAD-UK 11 102955036 102955036 single base substitution A G downstream_gene_variant ESAD-UK 11 102955036 102955036 single base substitution A G intron_variant ESAD-UK 11 102955036 102955036 single base substitution A G upstream_gene_variant ESAD-UK 11 102955257 102955257 single base substitution G C downstream_gene_variant ESAD-UK 11 102955257 102955257 single base substitution G C intron_variant ESAD-UK 11 102955257 102955257 single base substitution G C upstream_gene_variant ESAD-UK 11 102956654 102956654 single base substitution C G downstream_gene_variant ESAD-UK 11 102956654 102956654 single base substitution C G intron_variant ESAD-UK 11 102956654 102956654 single base substitution C G upstream_gene_variant ESAD-UK 11 102956781 102956781 single base substitution G C downstream_gene_variant ESAD-UK 11 102956781 102956781 single base substitution G C intron_variant ESAD-UK 11 102956781 102956781 single base substitution G C upstream_gene_variant ESAD-UK 11 102957007 102957007 single base substitution T A downstream_gene_variant ESAD-UK 11 102957007 102957007 single base substitution T A intron_variant ESAD-UK 11 102957007 102957007 single base substitution T A upstream_gene_variant ESAD-UK 11 102959696 102959696 single base substitution A G downstream_gene_variant ESAD-UK 11 102959696 102959696 single base substitution A G intron_variant ESAD-UK 11 102960570 102960570 single base substitution C T intron_variant ESAD-UK 11 102960570 102960570 single base substitution C T upstream_gene_variant ESAD-UK 11 102960705 102960705 single base substitution A C intron_variant ESAD-UK 11 102960705 102960705 single base substitution A C upstream_gene_variant ESAD-UK 11 102961222 102961222 single base substitution G A intron_variant ESAD-UK 11 102961222 102961222 single base substitution G A upstream_gene_variant ESAD-UK 11 102965619 102965619 single base substitution A C upstream_gene_variant ESAD-UK 11 102966017 102966017 single base substitution G A upstream_gene_variant ESAD-UK 11 102967357 102967357 single base substitution G C upstream_gene_variant LICA-CN 11 102933101 102933101 single base substitution C G 3_prime_UTR_variant LICA-CN 11 102933101 102933101 single base substitution C G downstream_gene_variant LICA-CN 11 102933101 102933101 single base substitution C G missense_variant R149P 446G>C LICA-CN 11 102933101 102933101 single base substitution C G missense_variant R234P 701G>C LICA-CN 11 102933101 102933101 single base substitution C G missense_variant V171L 511G>C LICA-FR 11 102938027 102938027 single base substitution G A intron_variant LICA-FR 11 102941324 102941324 single base substitution T C intron_variant LICA-FR 11 102948989 102948989 single base substitution C T intron_variant LICA-FR 11 102963619 102963619 single base substitution G C upstream_gene_variant LICA-FR 11 102965104 102965104 single base substitution A T upstream_gene_variant LINC-JP 11 102930023 102930023 single base substitution A G downstream_gene_variant LINC-JP 11 102934550 102934550 single base substitution T C downstream_gene_variant LINC-JP 11 102934550 102934550 single base substitution T C intron_variant LINC-JP 11 102957343 102957343 single base substitution C A downstream_gene_variant LINC-JP 11 102957343 102957343 single base substitution C A intron_variant LINC-JP 11 102957343 102957343 single base substitution C A upstream_gene_variant LINC-JP 11 102963021 102963021 single base substitution G A upstream_gene_variant LIRI-JP 11 102929754 102929754 single base substitution A C downstream_gene_variant LIRI-JP 11 102933663 102933663 single base substitution G A downstream_gene_variant LIRI-JP 11 102933663 102933663 single base substitution G A intron_variant LIRI-JP 11 102934955 102934955 single base substitution A C downstream_gene_variant LIRI-JP 11 102934955 102934955 single base substitution A C intron_variant LIRI-JP 11 102935246 102935246 single base substitution A G downstream_gene_variant LIRI-JP 11 102935246 102935246 single base substitution A G intron_variant LIRI-JP 11 102936074 102936074 single base substitution C T downstream_gene_variant LIRI-JP 11 102936074 102936074 single base substitution C T intron_variant LIRI-JP 11 102936939 102936939 single base substitution T C downstream_gene_variant LIRI-JP 11 102936939 102936939 single base substitution T C intron_variant LIRI-JP 11 102943135 102943135 single base substitution A C intron_variant LIRI-JP 11 102946520 102946520 single base substitution C A intron_variant LIRI-JP 11 102948264 102948264 single base substitution T A intron_variant LIRI-JP 11 102948810 102948810 single base substitution A C intron_variant LIRI-JP 11 102951041 102951041 single base substitution T C intron_variant LIRI-JP 11 102951865 102951865 single base substitution T C intron_variant LIRI-JP 11 102954605 102954605 single base substitution C T intron_variant LIRI-JP 11 102954605 102954605 single base substitution C T upstream_gene_variant LIRI-JP 11 102955443 102955443 single base substitution G A downstream_gene_variant LIRI-JP 11 102955443 102955443 single base substitution G A intron_variant LIRI-JP 11 102955443 102955443 single base substitution G A upstream_gene_variant LIRI-JP 11 102955727 102955727 single base substitution A T downstream_gene_variant LIRI-JP 11 102955727 102955727 single base substitution A T intron_variant LIRI-JP 11 102955727 102955727 single base substitution A T upstream_gene_variant LIRI-JP 11 102960052 102960052 single base substitution G T intron_variant LIRI-JP 11 102960052 102960052 single base substitution G T splice_region_variant LIRI-JP 11 102960052 102960052 single base substitution G T upstream_gene_variant LIRI-JP 11 102960353 102960356 deletion of <=200bp ATAA - intron_variant LIRI-JP 11 102960353 102960356 deletion of <=200bp ATAA - upstream_gene_variant LIRI-JP 11 102963430 102963430 single base substitution A G upstream_gene_variant LIRI-JP 11 102963854 102963854 single base substitution A G upstream_gene_variant LIRI-JP 11 102965307 102965307 single base substitution C T upstream_gene_variant LIRI-JP 11 102965643 102965643 single base substitution T C upstream_gene_variant LIRI-JP 11 102965694 102965694 single base substitution G A upstream_gene_variant LUSC-KR 11 102928816 102928816 single base substitution G A downstream_gene_variant LUSC-KR 11 102937178 102937178 single base substitution T C downstream_gene_variant LUSC-KR 11 102937178 102937178 single base substitution T C intron_variant LUSC-KR 11 102937854 102937854 single base substitution C A intron_variant LUSC-KR 11 102941330 102941330 single base substitution T G intron_variant LUSC-KR 11 102945834 102945834 single base substitution T G intron_variant LUSC-KR 11 102951289 102951289 single base substitution C G intron_variant LUSC-KR 11 102951573 102951573 single base substitution C G intron_variant LUSC-KR 11 102954398 102954398 single base substitution A G intron_variant LUSC-KR 11 102954398 102954398 single base substitution A G upstream_gene_variant LUSC-KR 11 102957464 102957464 single base substitution A T downstream_gene_variant LUSC-KR 11 102957464 102957464 single base substitution A T intron_variant LUSC-KR 11 102957464 102957464 single base substitution A T upstream_gene_variant LUSC-KR 11 102959153 102959153 single base substitution G A downstream_gene_variant LUSC-KR 11 102959153 102959153 single base substitution G A intron_variant LUSC-KR 11 102962141 102962141 single base substitution G A intron_variant LUSC-KR 11 102962141 102962141 single base substitution G A upstream_gene_variant MALY-DE 11 102946285 102946285 single base substitution A G intron_variant MALY-DE 11 102950355 102950355 insertion of <=200bp - A intron_variant MALY-DE 11 102950428 102950428 single base substitution A T intron_variant MALY-DE 11 102955757 102955757 single base substitution T G downstream_gene_variant MALY-DE 11 102955757 102955757 single base substitution T G intron_variant MALY-DE 11 102955757 102955757 single base substitution T G upstream_gene_variant MALY-DE 11 102964414 102964414 single base substitution A G upstream_gene_variant MELA-AU 11 102928210 102928210 single base substitution G A downstream_gene_variant MELA-AU 11 102928463 102928463 single base substitution G A downstream_gene_variant MELA-AU 11 102928986 102928986 single base substitution G A downstream_gene_variant MELA-AU 11 102930181 102930181 single base substitution A G downstream_gene_variant MELA-AU 11 102930919 102930919 single base substitution G A downstream_gene_variant MELA-AU 11 102931004 102931004 single base substitution G A downstream_gene_variant MELA-AU 11 102931682 102931682 single base substitution C T downstream_gene_variant MELA-AU 11 102932057 102932057 single base substitution G A downstream_gene_variant MELA-AU 11 102932060 102932060 single base substitution A G downstream_gene_variant MELA-AU 11 102932549 102932549 single base substitution G A downstream_gene_variant MELA-AU 11 102934129 102934129 single base substitution G A downstream_gene_variant MELA-AU 11 102934129 102934129 single base substitution G A intron_variant MELA-AU 11 102934223 102934223 single base substitution G A downstream_gene_variant MELA-AU 11 102934223 102934223 single base substitution G A intron_variant MELA-AU 11 102934475 102934475 single base substitution G A downstream_gene_variant MELA-AU 11 102934475 102934475 single base substitution G A intron_variant MELA-AU 11 102935401 102935401 single base substitution T G downstream_gene_variant MELA-AU 11 102935401 102935401 single base substitution T G intron_variant MELA-AU 11 102936106 102936106 single base substitution G A downstream_gene_variant MELA-AU 11 102936106 102936106 single base substitution G A intron_variant MELA-AU 11 102936952 102936952 single base substitution T A downstream_gene_variant MELA-AU 11 102936952 102936952 single base substitution T A intron_variant MELA-AU 11 102936954 102936954 single base substitution A C downstream_gene_variant MELA-AU 11 102936954 102936954 single base substitution A C intron_variant MELA-AU 11 102937231 102937231 single base substitution G A 3_prime_UTR_variant MELA-AU 11 102937231 102937231 single base substitution G A missense_variant S107L 320C>T MELA-AU 11 102937231 102937231 single base substitution G A missense_variant S136L 407C>T MELA-AU 11 102937231 102937231 single base substitution G A missense_variant S51L 152C>T MELA-AU 11 102937795 102937795 single base substitution A T intron_variant MELA-AU 11 102938330 102938330 single base substitution C A intron_variant MELA-AU 11 102938715 102938715 single base substitution G A intron_variant MELA-AU 11 102938867 102938867 single base substitution T A intron_variant MELA-AU 11 102939205 102939205 single base substitution G A intron_variant MELA-AU 11 102939220 102939220 single base substitution G A intron_variant MELA-AU 11 102939251 102939251 single base substitution G A intron_variant MELA-AU 11 102939314 102939314 single base substitution G A intron_variant MELA-AU 11 102939386 102939386 single base substitution G A intron_variant MELA-AU 11 102939663 102939663 single base substitution G A intron_variant MELA-AU 11 102940002 102940002 single base substitution G A intron_variant MELA-AU 11 102941250 102941250 single base substitution C A intron_variant MELA-AU 11 102942543 102942543 single base substitution T G intron_variant MELA-AU 11 102942856 102942856 single base substitution G C intron_variant MELA-AU 11 102943067 102943067 single base substitution C T intron_variant MELA-AU 11 102943090 102943090 single base substitution T A intron_variant MELA-AU 11 102943302 102943302 single base substitution A G intron_variant MELA-AU 11 102944153 102944153 single base substitution G A intron_variant MELA-AU 11 102944312 102944312 single base substitution G A intron_variant MELA-AU 11 102946300 102946300 single base substitution G A intron_variant MELA-AU 11 102948183 102948184 multiple base substitution (>=2bp and <=200bp) CA TG intron_variant MELA-AU 11 102949172 102949172 single base substitution T C intron_variant MELA-AU 11 102949253 102949253 single base substitution G A intron_variant MELA-AU 11 102949806 102949806 single base substitution G A intron_variant MELA-AU 11 102949823 102949823 single base substitution G A intron_variant MELA-AU 11 102951237 102951237 single base substitution G A intron_variant MELA-AU 11 102951238 102951238 single base substitution G A intron_variant MELA-AU 11 102951251 102951251 single base substitution G A intron_variant MELA-AU 11 102951428 102951428 single base substitution G A intron_variant MELA-AU 11 102952860 102952860 single base substitution A G intron_variant MELA-AU 11 102953917 102953917 single base substitution G A intron_variant MELA-AU 11 102953917 102953917 single base substitution G A upstream_gene_variant MELA-AU 11 102954594 102954594 single base substitution G A intron_variant MELA-AU 11 102954594 102954594 single base substitution G A upstream_gene_variant MELA-AU 11 102954776 102954776 single base substitution C T intron_variant MELA-AU 11 102954776 102954776 single base substitution C T upstream_gene_variant MELA-AU 11 102958034 102958034 single base substitution G A downstream_gene_variant MELA-AU 11 102958034 102958034 single base substitution G A intron_variant MELA-AU 11 102958034 102958034 single base substitution G A upstream_gene_variant MELA-AU 11 102959065 102959065 single base substitution G A downstream_gene_variant MELA-AU 11 102959065 102959065 single base substitution G A intron_variant MELA-AU 11 102960621 102960621 single base substitution T C intron_variant MELA-AU 11 102960621 102960621 single base substitution T C upstream_gene_variant MELA-AU 11 102960645 102960645 single base substitution C T intron_variant MELA-AU 11 102960645 102960645 single base substitution C T upstream_gene_variant MELA-AU 11 102961221 102961221 single base substitution G A intron_variant MELA-AU 11 102961221 102961221 single base substitution G A upstream_gene_variant MELA-AU 11 102961878 102961878 single base substitution A G intron_variant MELA-AU 11 102961878 102961878 single base substitution A G upstream_gene_variant MELA-AU 11 102962405 102962405 single base substitution G A exon_variant MELA-AU 11 102962405 102962405 single base substitution G A intron_variant MELA-AU 11 102962405 102962405 single base substitution G A upstream_gene_variant MELA-AU 11 102962953 102962953 single base substitution G A upstream_gene_variant MELA-AU 11 102962960 102962960 single base substitution G A upstream_gene_variant MELA-AU 11 102963800 102963800 single base substitution C T upstream_gene_variant MELA-AU 11 102964589 102964589 single base substitution C T upstream_gene_variant MELA-AU 11 102964952 102964952 single base substitution C T upstream_gene_variant MELA-AU 11 102965078 102965078 single base substitution T A upstream_gene_variant MELA-AU 11 102965285 102965285 single base substitution G A upstream_gene_variant MELA-AU 11 102965443 102965443 single base substitution T G upstream_gene_variant MELA-AU 11 102965596 102965596 single base substitution C T upstream_gene_variant MELA-AU 11 102965619 102965619 single base substitution A G upstream_gene_variant MELA-AU 11 102965715 102965715 single base substitution G A upstream_gene_variant MELA-AU 11 102965810 102965810 single base substitution C T upstream_gene_variant MELA-AU 11 102966315 102966315 single base substitution G A upstream_gene_variant MELA-AU 11 102966416 102966416 single base substitution C T upstream_gene_variant MELA-AU 11 102967142 102967142 single base substitution G A upstream_gene_variant MELA-AU 11 102967257 102967257 single base substitution C T upstream_gene_variant MELA-AU 11 102967477 102967477 single base substitution G A upstream_gene_variant MELA-AU 11 102967536 102967536 single base substitution G A upstream_gene_variant ORCA-IN 11 102939593 102939593 single base substitution C T intron_variant ORCA-IN 11 102967212 102967212 single base substitution C T upstream_gene_variant OV-AU 11 102933737 102933737 single base substitution T C downstream_gene_variant OV-AU 11 102933737 102933737 single base substitution T C intron_variant OV-AU 11 102937788 102937788 single base substitution G C intron_variant OV-AU 11 102941538 102941538 single base substitution A C intron_variant OV-AU 11 102942948 102942948 single base substitution C A intron_variant OV-AU 11 102949142 102949142 single base substitution A C intron_variant OV-AU 11 102951786 102951786 single base substitution G A intron_variant OV-AU 11 102952726 102952726 single base substitution T C intron_variant OV-AU 11 102952885 102952885 single base substitution G A intron_variant OV-AU 11 102958754 102958754 single base substitution C T downstream_gene_variant OV-AU 11 102958754 102958754 single base substitution C T intron_variant OV-AU 11 102966532 102966532 single base substitution G A upstream_gene_variant OV-AU 11 102966860 102966860 single base substitution C T upstream_gene_variant PACA-AU 11 102931144 102931144 single base substitution A C downstream_gene_variant PACA-AU 11 102931782 102931782 deletion of <=200bp T - downstream_gene_variant PACA-AU 11 102933216 102933216 single base substitution G A downstream_gene_variant PACA-AU 11 102933216 102933216 single base substitution G A intron_variant PACA-AU 11 102934918 102934918 single base substitution T C downstream_gene_variant PACA-AU 11 102934918 102934918 single base substitution T C intron_variant PACA-AU 11 102935275 102935275 insertion of <=200bp - A downstream_gene_variant PACA-AU 11 102935275 102935275 insertion of <=200bp - A intron_variant PACA-AU 11 102939567 102939567 single base substitution T A intron_variant PACA-AU 11 102949320 102949320 single base substitution T C intron_variant PACA-AU 11 102954665 102954665 single base substitution C T intron_variant PACA-AU 11 102954665 102954665 single base substitution C T upstream_gene_variant PACA-AU 11 102958344 102958344 single base substitution G A downstream_gene_variant PACA-AU 11 102958344 102958344 single base substitution G A intron_variant PACA-AU 11 102958344 102958344 single base substitution G A upstream_gene_variant PACA-AU 11 102962453 102962453 single base substitution T G exon_variant PACA-AU 11 102962453 102962453 single base substitution T G intron_variant PACA-AU 11 102962453 102962453 single base substitution T G upstream_gene_variant PACA-AU 11 102967083 102967083 single base substitution A C upstream_gene_variant PACA-CA 11 102927876 102927876 single base substitution A G downstream_gene_variant PACA-CA 11 102929625 102929625 insertion of <=200bp - G downstream_gene_variant PACA-CA 11 102929626 102929626 deletion of <=200bp G - downstream_gene_variant PACA-CA 11 102930083 102930083 single base substitution C G downstream_gene_variant PACA-CA 11 102933019 102933019 single base substitution C T 3_prime_UTR_variant PACA-CA 11 102933019 102933019 single base substitution C T downstream_gene_variant PACA-CA 11 102935201 102935201 single base substitution G T downstream_gene_variant PACA-CA 11 102935201 102935201 single base substitution G T intron_variant PACA-CA 11 102937081 102937081 single base substitution C T 3_prime_UTR_variant PACA-CA 11 102937081 102937081 single base substitution C T downstream_gene_variant PACA-CA 11 102937081 102937081 single base substitution C T missense_variant D129N 385G>A PACA-CA 11 102937081 102937081 single base substitution C T missense_variant D158N 472G>A PACA-CA 11 102937081 102937081 single base substitution C T missense_variant D73N 217G>A PACA-CA 11 102937410 102937410 single base substitution T C intron_variant PACA-CA 11 102938682 102938682 single base substitution A G intron_variant PACA-CA 11 102941009 102941009 single base substitution G C intron_variant PACA-CA 11 102942087 102942087 single base substitution A G intron_variant PACA-CA 11 102942093 102942093 single base substitution C G intron_variant PACA-CA 11 102944227 102944227 single base substitution A G intron_variant PACA-CA 11 102945603 102945603 single base substitution C T intron_variant PACA-CA 11 102947345 102947345 single base substitution C T intron_variant PACA-CA 11 102947798 102947798 single base substitution G A intron_variant PACA-CA 11 102950885 102950885 single base substitution C A intron_variant PACA-CA 11 102951417 102951417 single base substitution C G intron_variant PACA-CA 11 102953711 102953711 single base substitution T A intron_variant PACA-CA 11 102953711 102953711 single base substitution T A upstream_gene_variant PACA-CA 11 102955502 102955502 single base substitution T C downstream_gene_variant PACA-CA 11 102955502 102955502 single base substitution T C intron_variant PACA-CA 11 102955502 102955502 single base substitution T C upstream_gene_variant PACA-CA 11 102958749 102958749 single base substitution G A downstream_gene_variant PACA-CA 11 102958749 102958749 single base substitution G A intron_variant PACA-CA 11 102962324 102962324 single base substitution C T 3_prime_UTR_variant PACA-CA 11 102962324 102962324 single base substitution C T intron_variant PACA-CA 11 102962324 102962324 single base substitution C T upstream_gene_variant PACA-CA 11 102962549 102962549 single base substitution T C exon_variant PACA-CA 11 102962549 102962549 single base substitution T C missense_variant E18G 53A>G PACA-CA 11 102962549 102962549 single base substitution T C upstream_gene_variant PACA-CA 11 102966027 102966027 insertion of <=200bp - T upstream_gene_variant PACA-CA 11 102967725 102967725 single base substitution C T upstream_gene_variant PACA-CA 11 102967757 102967757 single base substitution C T upstream_gene_variant PACA-CA 11 102967899 102967899 single base substitution G A upstream_gene_variant PAEN-IT 11 102946844 102946844 single base substitution G T intron_variant PAEN-IT 11 102946919 102946919 single base substitution C T intron_variant PBCA-DE 11 102933740 102933740 single base substitution G A downstream_gene_variant PBCA-DE 11 102933740 102933740 single base substitution G A intron_variant PBCA-DE 11 102936589 102936589 single base substitution T C downstream_gene_variant PBCA-DE 11 102936589 102936589 single base substitution T C intron_variant PBCA-DE 11 102941426 102941426 single base substitution G T intron_variant PBCA-DE 11 102950355 102950355 insertion of <=200bp - A intron_variant PBCA-DE 11 102954007 102954007 single base substitution T C 3_prime_UTR_variant PBCA-DE 11 102954007 102954007 single base substitution T C exon_variant PBCA-DE 11 102954007 102954007 single base substitution T C intron_variant PBCA-DE 11 102954007 102954007 single base substitution T C missense_variant D47G 140A>G PBCA-DE 11 102954007 102954007 single base substitution T C missense_variant D76G 227A>G PBCA-DE 11 102954007 102954007 single base substitution T C upstream_gene_variant PBCA-DE 11 102967277 102967277 insertion of <=200bp - A upstream_gene_variant PRAD-CA 11 102933657 102933657 single base substitution C T downstream_gene_variant PRAD-CA 11 102933657 102933657 single base substitution C T intron_variant PRAD-CA 11 102933815 102933815 single base substitution C T downstream_gene_variant PRAD-CA 11 102933815 102933815 single base substitution C T intron_variant PRAD-UK 11 102938707 102938707 single base substitution G T intron_variant PRAD-UK 11 102942664 102942664 single base substitution A T intron_variant PRAD-UK 11 102943496 102943496 single base substitution G T intron_variant PRAD-UK 11 102944566 102944566 single base substitution C T intron_variant PRAD-UK 11 102966105 102966105 single base substitution C A upstream_gene_variant RECA-EU 11 102930684 102930684 single base substitution A C downstream_gene_variant RECA-EU 11 102930767 102930767 single base substitution T C downstream_gene_variant RECA-EU 11 102935649 102935649 single base substitution A G downstream_gene_variant RECA-EU 11 102935649 102935649 single base substitution A G intron_variant RECA-EU 11 102938642 102938642 single base substitution C T intron_variant RECA-EU 11 102939260 102939260 single base substitution T A intron_variant RECA-EU 11 102952748 102952748 single base substitution T C intron_variant RECA-EU 11 102959020 102959020 single base substitution T C downstream_gene_variant RECA-EU 11 102959020 102959020 single base substitution T C intron_variant RECA-EU 11 102964706 102964706 single base substitution C A upstream_gene_variant SKCA-BR 11 102929094 102929094 single base substitution G A downstream_gene_variant SKCA-BR 11 102930486 102930486 single base substitution T G downstream_gene_variant SKCA-BR 11 102934418 102934418 single base substitution A G downstream_gene_variant SKCA-BR 11 102934418 102934418 single base substitution A G intron_variant SKCA-BR 11 102935741 102935741 single base substitution T C downstream_gene_variant SKCA-BR 11 102935741 102935741 single base substitution T C intron_variant SKCA-BR 11 102943495 102943495 insertion of <=200bp - GT intron_variant SKCA-BR 11 102945430 102945430 single base substitution G A intron_variant SKCA-BR 11 102945993 102945993 single base substitution G A intron_variant SKCA-BR 11 102955491 102955491 single base substitution G A downstream_gene_variant SKCA-BR 11 102955491 102955491 single base substitution G A intron_variant SKCA-BR 11 102955491 102955491 single base substitution G A upstream_gene_variant SKCA-BR 11 102957498 102957498 single base substitution G A downstream_gene_variant SKCA-BR 11 102957498 102957498 single base substitution G A intron_variant SKCA-BR 11 102957498 102957498 single base substitution G A upstream_gene_variant SKCA-BR 11 102957500 102957500 single base substitution A T downstream_gene_variant SKCA-BR 11 102957500 102957500 single base substitution A T intron_variant SKCA-BR 11 102957500 102957500 single base substitution A T upstream_gene_variant SKCA-BR 11 102965889 102965889 single base substitution G A upstream_gene_variant SKCA-BR 11 102966336 102966336 single base substitution G A upstream_gene_variant SKCM-US 11 102937231 102937231 single base substitution G A 3_prime_UTR_variant SKCM-US 11 102937231 102937231 single base substitution G A missense_variant S107L 320C>T SKCM-US 11 102937231 102937231 single base substitution G A missense_variant S136L 407C>T SKCM-US 11 102937231 102937231 single base substitution G A missense_variant S51L 152C>T STAD-US 11 102937031 102937031 single base substitution C T 3_prime_UTR_variant STAD-US 11 102937031 102937031 single base substitution C T downstream_gene_variant STAD-US 11 102937031 102937031 single base substitution C T stop_gained W145* 435G>A STAD-US 11 102937031 102937031 single base substitution C T stop_gained W174* 522G>A STAD-US 11 102937031 102937031 single base substitution C T stop_gained W89* 267G>A STAD-US 11 102953515 102953515 deletion of <=200bp A - 3_prime_UTR_variant STAD-US 11 102953515 102953515 deletion of <=200bp A - exon_variant STAD-US 11 102953515 102953515 deletion of <=200bp A - frameshift_variant F101 STAD-US 11 102953515 102953515 deletion of <=200bp A - frameshift_variant F72 STAD-US 11 102953515 102953515 deletion of <=200bp A - intron_variant STAD-US 11 102953515 102953515 insertion of <=200bp - A 3_prime_UTR_variant STAD-US 11 102953515 102953515 insertion of <=200bp - A exon_variant STAD-US 11 102953515 102953515 insertion of <=200bp - A frameshift_variant F101F? STAD-US 11 102953515 102953515 insertion of <=200bp - A frameshift_variant F72F? STAD-US 11 102953515 102953515 insertion of <=200bp - A intron_variant THCA-SA 11 102928855 102928855 single base substitution T C downstream_gene_variant THCA-SA 11 102929625 102929625 single base substitution T G downstream_gene_variant THCA-SA 11 102929924 102929924 single base substitution C G downstream_gene_variant THCA-SA 11 102930285 102930285 single base substitution A G downstream_gene_variant THCA-SA 11 102930407 102930407 single base substitution C A downstream_gene_variant THCA-SA 11 102932440 102932440 single base substitution T C downstream_gene_variant UCEC-US 11 102937031 102937031 single base substitution C T 3_prime_UTR_variant UCEC-US 11 102937031 102937031 single base substitution C T downstream_gene_variant UCEC-US 11 102937031 102937031 single base substitution C T stop_gained W145* 435G>A UCEC-US 11 102937031 102937031 single base substitution C T stop_gained W174* 522G>A UCEC-US 11 102937031 102937031 single base substitution C T stop_gained W89* 267G>A UCEC-US 11 102937066 102937066 single base substitution T C 3_prime_UTR_variant UCEC-US 11 102937066 102937066 single base substitution T C downstream_gene_variant UCEC-US 11 102937066 102937066 single base substitution T C missense_variant K134E 400A>G UCEC-US 11 102937066 102937066 single base substitution T C missense_variant K163E 487A>G UCEC-US 11 102937066 102937066 single base substitution T C missense_variant K78E 232A>G UCEC-US 11 102953482 102953482 single base substitution T C 3_prime_UTR_variant UCEC-US 11 102953482 102953482 single base substitution T C exon_variant UCEC-US 11 102953482 102953482 single base substitution T C intron_variant UCEC-US 11 102953482 102953482 single base substitution T C synonymous_variant S112S 336A>G UCEC-US 11 102953482 102953482 single base substitution T C synonymous_variant S83S 249A>G

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-E2-A1IN-01 COSM1474944 c.643G>A p.D215N Substitution - Missense 11:103064290-103064290 - 145 COSM3735105 c.140C>T p.S47L Substitution - Missense 11:103089265-103089265 - ESO-0001 COSM1249839 c.342-6_342-3delTTTA p.? Unknown 11:103066570-103066573 - TCGA-AX-A0J1-01 COSM922323 c.522G>A p.W174* Substitution - Nonsense 11:103066302-103066302 - T1154 COSM4676638 c.382T>C p.L128L Substitution - coding silent 11:103066527-103066527 - RK117_C01 COSM3699964 c.87-5C>A p.? Unknown 11:103089323-103089323 - PCSI_0048_Pa_P COSM216464 c.53A>G p.E18G Substitution - Missense 11:103091820-103091820 - 35M COSM3442767 c.407C>T p.S136L Substitution - Missense 11:103066502-103066502 - TCGA-D1-A17R-01 COSM922324 c.487A>G p.K163E Substitution - Missense 11:103066337-103066337 - 2521243 COSM5886708 c.591G>A p.W197* Substitution - Nonsense 11:103064342-103064342 - TCGA-D3-A3C7-06 COSM3442767 c.407C>T p.S136L Substitution - Missense 11:103066502-103066502 - TCGA-CK-5914-01 COSM1350434 c.348C>T p.D116D Substitution - coding silent 11:103066561-103066561 - TCGA-EK-A3GK-01 COSM4853163 c.184G>A p.D62N Substitution - Missense 11:103083321-103083321 - 2521243 COSM5613290 c.286G>A p.E96K Substitution - Missense 11:103082803-103082803 - PD11741a COSM5783117 c.217T>G p.F73V Substitution - Missense 11:103083288-103083288 - HCC137T COSM5811304 c.701G>C p.R234P Substitution - Missense 11:103062372-103062372 - LUAD-S00484 COSM342765 c.614G>C p.R205T Substitution - Missense 11:103064319-103064319 - 587376 COSM1203178 c.419A>G p.N140S Substitution - Missense 11:103066490-103066490 - SNUH_G10_S1 COSM3998185 c.450+10A>G p.? Unknown 11:103066449-103066449 - PCSI0048 COSM216464 c.53A>G p.E18G Substitution - Missense 11:103091820-103091820 - TCGA-D7-5578-01 COSM922323 c.522G>A p.W174* Substitution - Nonsense 11:103066302-103066302 - 12820 COSM5613290 c.286G>A p.E96K Substitution - Missense 11:103082803-103082803 - pfg181T COSM4759600 c.205G>T p.G69* Substitution - Nonsense 11:103083300-103083300 - PCSI_0048_Pa_P_526 COSM216464 c.53A>G p.E18G Substitution - Missense 11:103091820-103091820 - ICGC_MB5 COSM215447 c.227A>G p.D76G Substitution - Missense 11:103083278-103083278 - TCGA-DI-A0WH-01 COSM922325 c.336A>G p.S112S Substitution - coding silent 11:103082753-103082753 - TCGA-EE-A2GO-06 COSM3442767 c.407C>T p.S136L Substitution - Missense 11:103066502-103066502 - PT37 COSM3442767 c.407C>T p.S136L Substitution - Missense 11:103066502-103066502 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.503716 11q22.3 1522839|dbSNP|BC004169|A/G|non-coding||1049|Confirmed

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A - Frameshift p.F101Lfs*7 c.303delT 11 102953515 STAD C T Missense p.D215N c.643G>A 11 102935019 BRCA C T Missense p.E96K c.286G>A 11 102953532 NSCLC C T Nonsense p.W174* c.522G>A 11 102937031 STAD G A Missense p.S136L c.407C>T 11 102937231 CM G C Missense p.Q196E c.586C>G 11 102935076 MM G T Missense p.S164Y c.491C>A 11 102937062 CM TAAA - IntronicDeletion . c.342-6_342-3delTTTA 11 102937299 ESCA T C Missense p.D76G c.227A>G 11 102954007 MB T C Missense p.E18G c.53A>G 11 102962549 PAAD T C Missense p.K163E c.487A>G 11 102937066 UCEC T C Synonymous p.S112S c.336A>G 11 102953482 UCEC