PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus YWHAQ RPTOR 18439900 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP G P GP P GP G RPS6 RPTOR 21045808 biogrid,intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G FKBP8 RPTOR 17991864 innatedb,biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR AMBRA1 23524951 biogrid,dip exp GP GP G P GP G P P G P GP P G G P GP P G GP GP GP GP P G P GP G RPTOR PIH1D1 24036451 intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR TELO2 23263282 dip exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G CUL4B RPTOR 23297343 biogrid exp GP GP G P GP G P P G P GP GP G P GP P G GP GP GP GP P GP P GP G HIF1A RPTOR 17502379 innatedb,biogrid exp GP GP G P GP G P G P G P GP G P GP P G GP G GP G P GP P GP G CHUK RPTOR 18519641 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G MAPK8 RPTOR 22493283 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G PLD2 RPTOR 16837165 innatedb,hprd,biogrid exp GP GP G P GP G P P G P GP P G G P GP P P G GP GP GP G P G P GP G LAMTOR5 RPTOR 25561175,22980980 intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR TXNDC15 26186194 biogrid exp GP GP G GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR GTF3C2 20543138 dip exp G GP G P GP G P P G P G P GP G P GP P G G G G GP P GP P G G TIRAP RPTOR 21903422 innatedb,biogrid,intact exp G GP G GP G P P G P G G G P GP P P G GP G GP GP P G P GP G ULK1 RPTOR 21460630 biogrid exp G G G G G G G G G G G G G G G G G G RPTOR IKBKG 18519641 biogrid exp G G G G G G G G G G G G G G G G G G NTRK1 RPTOR 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P RPTOR MARK4 23184942 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P G G GP GP GP P GP P GP G IRS1 RPTOR 19561084,16354680 hprd,biogrid exp GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP GP P GP P P G RPTOR PREX1 17565979,21339740 innatedb,biogrid,i2d,intact exp GP GP G P GP G P P G P G P GP G P GP P G GP GP GP GP P GP P GP G CUL4A RPTOR 23297343 biogrid exp G G G G G G G G G G G G G G G G G G NT5E RPTOR 26186194 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP P P P GP P GP G RPTOR LARS 22424946 biogrid,intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR USP9X 22544753 biogrid exp GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G SQSTM1 RPTOR 21981924 biogrid exp GP GP G P G G P G P GP P GP G P G P P G GP GP GP GP P GP P GP G RPTOR ETV7 24036451 intact exp G G G P GP G P G P G G P GP G G G G G P G P GP G DDB1 RPTOR 23297343 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR FBXO9 23263282 dip exp G G G G G G G G G G G G G G G G G G LAMP2 RPTOR 23953116 intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR SIRT1 21471201 biogrid,intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G CCNB1 RPTOR 20169205 biogrid exp P G P G G P G P GP P G G GP G P P P P GP PRKAA1 RPTOR 18439900 biogrid exp GP GP P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP TTI1 RPTOR 23263282 dip exp GP GP G P GP G P P G P GP P G G P GP P G GP GP G GP P G P GP G GNB1 RPTOR 24462769 biogrid exp G GP G GP G P P G P GP P G G P GP P P G G G GP G P G P GP G RAB1A RPTOR 25446900 intact exp GP GP G GP G P P G P GP P GP G P GP P P G GP GP GP G P GP P GP G RAP1B RPTOR 24337580 biogrid exp G G G G G G G G G G G G G G G G G G PRKAA2 RPTOR 18439900 biogrid exp G GP G GP G P P G P P G G P GP P P G G GP GP P G P GP G IKBKB RPTOR 18519641,23872070 biogrid exp GP GP G P GP G P G P G P GP G P GP P P G GP GP GP G P GP P GP G RPTOR IRS2 19561084 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G BAG3 RPTOR 26186194 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR SPAG5 23953116 intact exp P GP G P GP G P P G P GP P GP P GP P P G GP P P GP P GP P GP G RPTOR MOV10 22658674 biogrid exp G G G G G G G G G G G G G G YWHAG RPTOR 18439900 innatedb exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G HTR6 RPTOR 23027611 biogrid exp G G G G G G G G G G G G G G G G G G SCAP RPTOR 26344197 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G UCHL1 RPTOR 23297343 biogrid exp G G G GP G P G P G G G GP P G G G G G G GP G EIF3A RPTOR 23953116 intact exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR ICK 22356909 biogrid exp G G G G G G G G G G G RPS6KA1 RPTOR 18722121 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P G GP GP GP GP P GP P GP G RPTOR FAF2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G SGK1 RPTOR 18570873 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G MAPK3 RPTOR 21071439 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G HSPA4 RPTOR 16962653 biogrid exp GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G PDIA3 RPTOR 21321085 biogrid exp GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP G P GP P GP G GNG2 RPTOR 24462769 biogrid exp G G G GP G P G P G GP G GP P P G GP G GP G GP P GP G LAMTOR4 RPTOR 25561175,22980980 intact exp GP GP G P GP G P P G P GP P GP G P GP P G GP GP GP GP P GP P GP G PDK1 RPTOR 24516643,12150926 biogrid exp GP GP G P GP P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP GTF3C1 RPTOR 20543138 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G G3BP1 RPTOR 23953116 intact exp GP GP G P GP G P G P G P GP G P GP P P G GP GP GP GP P GP P GP G IQGAP1 RPTOR 22328503 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP G P GP P GP G RPTOR NXF1 22658674 biogrid exp GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G EIF4EBP2 RPTOR 20347422 biogrid exp, ortho G G G G G G G G G G G G G G G G G G RPTOR TRAF6 23911927 biogrid exp, ortho GP GP G P G G P P G P GP P G G P G P G GP GP GP G P GP P GP G RPTOR RPTOR 24403073,22424946 biogrid exp, ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G XPO1 RPTOR 26673895 biogrid exp, ortho GP GP G P GP G P P G P G P GP G P GP P P G GP GP GP GP P GP P GP G YWHAZ RPTOR 18439900, 25402006 innatedb exp, ortho, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR MLST8 24403073,18030348,16919458,20562859,17565979,21321085,12408816,16798736,20169205,12718876, 25402006, 23023127, 21836163 innatedb,hprd,biogrid,intact exp, ortho, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPS6KB1 RPTOR 22493283,16837165,12604610,23184942,15809305,19402821,16183647,12150926,21071439, 25402006 hprd,biogrid exp, ortho, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G MTOR RPTOR 18676370,23911927,12747827,21177249,25446900,17599906,23297343,21321085,19145465,16183647,12150926,18955708,17461779,18505677,20169205,23872070,15459249,17043309,21614075,12665511,17386266,19114562,20427287,18519641,19875983,16798736,17277771,16603397,16837165,16919458,22258093,16631613,20381137,22544753,24375676,21071439,15268862,16847060,18722121,24516643,25332233,19446321,17565979,15809305,17604271,16962653,12408816,18614546,22493283,18030348,12719976,1683716516603397,12150925,22356909,12718876,16354680,24403073,22424946,19619545,23953116,21045808,15066126,24036451,18570873,24337580,15467718, 25402006 innatedb,hprd,biogrid,i2d,mint,intact,dip exp, ortho, pred G GP G GP G G G P G G GP G G GP G G G P G G EIF3B RPTOR 21045808,16286006, 25402006, 21836163 innatedb,biogrid exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G LAMTOR1 RPTOR 25561175,22980980, 25402006 intact exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RRAGB RPTOR 21981924,24337580,18497260, 25402006 innatedb,biogrid exp, pred GP P G P GP P P G P P P P GP P G P GP P P P P P P EIF4EBP1 RPTOR 18722121,24403073,12604610,12747827,12665511,16824195,17502379,15767663,16798736,12150926,18955708,18337751,22493283,16837165,12912989,21071439, 25402006 hprd,biogrid,mint,intact exp, pred G G G G G G G G G G G MAPK1 RPTOR 21325048,21071439, 25402006 biogrid exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RRAGA RPTOR 23184942,21816923,26186194,24337580,18497260,25561175, 25402006 innatedb,biogrid,intact exp, pred GP GP G P GP G P P G P G P GP G P GP P G GP GP GP GP P GP P GP G RPTOR RRAGC 21981924,21816923,25446900,24337580,18497260,25561175, 25402006 innatedb,biogrid,intact exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR DEPTOR 20169205,19446321, 25402006 biogrid,intact exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RICTOR RPTOR 19145465,19446321, 25402006 biogrid,intact exp, pred GP GP G P GP G P P G P GP P GP G P GP P G GP GP GP GP P GP P GP G PRR5L RPTOR 18030348, 25402006 innatedb exp, pred G G G G G G G G G G G G G G G G G AKT1 RPTOR 21339740, 25402006 biogrid exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G FKBP1A RPTOR 15268862,15467718, 25402006 biogrid exp, pred G GP G GP G P G P GP G G P GP P P G GP GP GP G P G P GP G EIF4E RPTOR 16798736, 25402006 biogrid exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR EIF3C 16286006, 21836163 biogrid exp, pred P GP P P P P P GP P GP P P P P P GP GP P P GP P GP G RPTOR AKT1S1 18570873,18030348,19446321,17386266,17604271,17517883,23953116,17277771,20169205,18215133, 25402006, 21836163 innatedb,biogrid,intact exp, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P P P GP G RPTOR LAMTOR2 20381137,22980980, 25402006 biogrid,intact exp, pred GP G G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR LAMTOR3 25561175, 25402006 intact exp, pred GP GP G P GP G P P G P G P GP G P GP P P G GP GP GP G P GP P GP G RHEB RPTOR 15854902,17470430,15878852,25446900,16631613,24337580, 25402006 innatedb,hprd,biogrid,i2d,intact exp, pred GP G G P GP G P P G P GP P GP G P GP P G GP GP GP GP P GP P GP G RPTOR RRAGD 22424946,24337580,18497260, 25402006 innatedb,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G SEPT7 RPTOR ortho GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP G P GP P GP G HSPD1 RPTOR ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP G P GP P GP G RPTOR IPO4 ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G MOCS3 RPTOR ortho P GP G P GP G P G P GP P P G P GP P G GP G G GP P P GP G GPC5 RPTOR ortho P G GP G P G P P P GP P G P P P P P GP NCAM1 RPTOR ortho G GP G GP G P P G G G G GP P G G G G G P GP G NAP1L1 RPTOR ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G FKBP2 RPTOR ortho G GP G P GP G P G P GP P GP G P GP P G GP GP GP G P GP P GP G FBP1 RPTOR ortho G GP G G G G P GP P G G P G G G GP GP G P G P G G CLTC RPTOR ortho GP GP G P GP G P P G P GP P GP G P GP P G GP GP GP G P GP P GP G PPIF RPTOR ortho G G G G G G G G G G G G G G G G G G RPTOR ASF1A ortho G G G G G G G G G G G G G G G G G G RHOA RPTOR ortho GP GP G P GP G P P G P G P GP G P GP P P G GP GP GP GP P GP P GP G CCT8 RPTOR ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G YY1 RPTOR ortho GP GP G P GP G P P G P G P GP G P GP P P G GP GP GP GP P GP P GP G PABPC1L RPTOR ortho G G G G G G G G G DNAJA2 RPTOR ortho GP GP G P GP G P P G P GP GP G P GP P P G GP GP GP GP P GP P GP G EIF3I RPTOR ortho GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR INO80 ortho G G G G G G G G G G G G G G G G G G PPP1R7 RPTOR 16082366 ortho, pred GP GP G P GP G P P G P GP P GP G P GP P G GP GP GP GP P GP P GP G RPTOR MAPKAP1 25402006 ortho, pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RBBP7 RPTOR 23023127 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G HSPA1A, HSPA1B RPTOR 25402006 pred P P P P P P P P P P P P P P P P P P P P P P SFN RPTOR 25402006 pred GP G G G G G G P G G G P G G GP G G G G G PPP3CA RPTOR 25402006 pred GP GP G GP G P G P G GP G P GP P G G GP G G P GP P GP G NCBP1 RPTOR 25402006 pred GP GP G P GP G P P P P P GP G P GP P P G GP GP GP GP P GP P GP RPL37 RPTOR 21836163 pred G G G G G G G G G G G G G G G G G G PRR5 RPTOR 25402006 pred GP G G GP G P P G P GP P G G P GP P P G GP GP GP GP P G P GP G DCP2 RPTOR 16082366 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G PPP2CA RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G YWHAH RPTOR 25402006 pred GP GP G P GP G P P G P GP P G G P GP P P G GP GP GP GP P GP P GP G RPTOR TSC1 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G STAT3 RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G AKT2 RPTOR 25402006 pred GP GP G P GP G P G P GP P GP G P GP P P G GP GP GP G P GP P GP G YWHAE RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR NAT9 21836163 pred G G G P G G G G G G G G GP G GP G GP G G EIF3E RPTOR 21836163 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP G P GP P GP G CSNK2A1 RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G ATM RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G TSC2 RPTOR 25402006 pred G GP G GP G P P G P GP P G G P GP P P G GP G G G P G P GP G SMAD7 RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P P G RPTOR MAP3K2 25402006 pred G GP G GP G P P G P GP G G P GP G GP GP GP GP P G P GP G CRTC1 RPTOR 21836163 pred GP G P GP G P P G P P P P P GP P G P P P P P P P GP BRAF RPTOR 25402006 pred GP GP G P GP G P P G P GP P GP P GP P P G GP GP GP GP P GP P GP G RPS9 RPTOR 25402006 pred GP GP G P GP G P G P GP P GP G P GP P G GP GP GP G P G P GP G RPTOR TRAF4 25402006 pred G GP G GP G P P G P GP P G G P GP P G GP G GP P P G P GP G CSNK2A2 RPTOR 25402006 pred G G G G G G G G G G G G G G G G G G EIF3H RPTOR 21836163 pred GP GP G P GP G P P G P GP P GP G P GP P P G GP GP GP GP P GP P GP G RPTOR RHEBL1 23023127 pred GP P G P GP G P P G P P P GP G P GP P P G GP P P GP P GP P GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8N122 - 15467718 - C 3 Q8N122 P42345 - 15718470 - X 2 Q8N122 P42345 - 15718470 - X 2 Q8N122 A0A090N900 - 15854902 - X 2 Q8N122 coimmunoprecipitation 12718876 association C 3 Q8N122 coimmunoprecipitation 15467718 association C 3 Q8N122 anti bait coimmunoprecipitation 15268862 association C 3 Q8N122 coimmunoprecipitation 15718470 association C 3 Q8N122 P42345 coimmunoprecipitation 12150926 association X 2 Q8N122 P42345 coimmunoprecipitation 12150925 association X 2 Q8N122 anti bait coimmunoprecipitation 23263282 - C 4 Q8N122 anti tag coimmunoprecipitation 23263282 - C 3 Q8N122 anti bait coimmunoprecipitation 23263282 - C 3 Q8N122 anti bait coimmunoprecipitation 20543138 - C 3 Q8N122 anti tag coimmunoprecipitation 23263282 - C 4 Q9Y4R8 Q8N122 anti tag coimmunoprecipitation 23263282 physical association X 2 Q9Y4R8 Q8N122 anti bait coimmunoprecipitation 23263282 physical association X 2 Q9Y4R8 Q8N122 anti bait coimmunoprecipitation 23263282 physical association X 2 Q9Y4R8 Q8N122 anti tag coimmunoprecipitation 23263282 physical association X 2 Q8N122 Q9C0C7 anti tag coimmunoprecipitation 23524951 physical association X 2 Q8N122 Q9UK97 anti tag coimmunoprecipitation 23263282 physical association X 2 Q8N122 Q9UK97 anti tag coimmunoprecipitation 23263282 physical association X 2 Q8N122 anti tag coimmunoprecipitation 23263282 - C 4 O43156 Q8N122 anti bait coimmunoprecipitation 23263282 physical association X 2 O43156 Q8N122 anti bait coimmunoprecipitation 23263282 physical association X 2 O43156 Q8N122 anti tag coimmunoprecipitation 23263282 physical association X 2 O43156 Q8N122 anti tag coimmunoprecipitation 23263282 physical association X 2 Q8N122 P42345 solid phase assay 21614075 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 18955708 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 23263282 physical association X 2 Q8N122 Q8WUA4 anti bait coimmunoprecipitation 20543138 physical association X 2 Q8N122 Q8WUA4 anti bait coimmunoprecipitation 20543138 physical association X 2 Q8N122 Q8WUA4 anti bait coimmunoprecipitation 20543138 physical association X 2 Q8N122 in vivo 16837165 - C 3 Q8N122 in vivo 16837165 - C 3 Q8N122 in vivo 16837165 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 in vivo 12604610 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 in vivo 12604610 - C 3 Q8N122 in vivo 12604610 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 in vivo 12150926,12604610 - C 3 Q8N122 A0A024R499 in vitro 16354680 - X 2 Q8N122 Q13541 in vivo 12150926,12604610,12747827,12912989,16824195 - X 2 Q8N122 Q13541 in vitro 12150926,12604610,12747827,12912989,16824195 - X 2 Q8N122 O14939 in vitro 16837165 - X 2 Q8N122 Q9BVC4 in vivo 12718876 - X 2 Q8N122 A0A024R499 in vitro 16354680 - X 2 Q8N122 Q13541 in vivo 12150926,12604610,12747827,12912989,16824195 - X 2 Q8N122 Q13541 in vitro 12150926,12604610,12747827,12912989,16824195 - X 2 Q8N122 O14939 in vitro 16837165 - X 2 Q8N122 Q9BVC4 in vivo 12718876 - X 2 Q8N122 in vivo 16286006 - C 3 Q8N122 in vivo 16286006 - C 3 Q8N122 in vivo 16286006 - C 3 Q8N122 P42345 in vitro 12150925,12150926,15066126,16354680,1683716516603397 - X 2 Q8N122 P42345 in vivo 12150925,12150926,15066126,16354680,1683716516603397 - X 2 Q8N122 A0A090N900 in vitro 16631613 - X 2 Q8N122 A0A090N900 in vivo 16631613 - X 2 Q8N122 A0A090N900 in vitro 16631613 - X 2 Q8N122 A0A090N900 in vivo 16631613 - X 2 Q8N122 P42345 in vivo 12150925,12150926,15066126,16354680,1683716516603397 - X 2 Q8N122 P42345 in vitro 12150925,12150926,15066126,16354680,1683716516603397 - X 2 Q8N122 P23443 in vitro 12150926,12604610,16183647 - X 2 Q8N122 P23443 in vitro 12150926,12604610,16183647 - X 2 Q8N122 anti bait coimmunoprecipitation 24036451 association C 3 Q8N122 anti tag coimmunoprecipitation 22424946 association C 4 Q8N122 anti tag coimmunoprecipitation 22424946 association C 4 Q8N122 anti bait coimmunoprecipitation 24036451 association C 4 Q8N122 anti tag coimmunoprecipitation 25561175 association C 5 Q8N122 cross-linking study 22980980 association C 3 Q8N122 anti bait coimmunoprecipitation 23953116 association C 3 Q8N122 anti bait coimmunoprecipitation 22424946 association C 3 Q8N122 anti tag coimmunoprecipitation 22424946 association C 3 Q8N122 anti bait coimmunoprecipitation 17461779 association C 6 Q8N122 pull down 12150926 association C 3 Q8N122 anti tag coimmunoprecipitation 12150926 association C 3 Q8N122 anti bait coimmunoprecipitation 23953116 association C 3 Q8N122 anti bait coimmunoprecipitation 23953116 association C 3 Q8N122 anti bait coimmunoprecipitation 21045808 association C 3 Q8N122 anti tag coimmunoprecipitation 25561175 association C 10 Q8N122 cosedimentation through density gradient 21045808 colocalization C 4 Q8N122 cross-linking study 22980980 association C 3 Q8N122 anti tag coimmunoprecipitation 25561175 association C 8 Q8N122 anti bait coimmunoprecipitation 23953116 association C 4 Q8N122 anti bait coimmunoprecipitation 23953116 association C 4 Q8N122 anti bait coimmunoprecipitation 23953116 association C 4 Q8N122 anti tag coimmunoprecipitation 25561175 association C 11 Q8N122 anti tag coimmunoprecipitation 25561175 association C 11 Q8N122 anti tag coimmunoprecipitation 25561175 association C 11 Q8N122 anti tag coimmunoprecipitation 25561175 association C 11 Q8N122 anti bait coimmunoprecipitation 23953116 association C 4 Q8N122 Q13541 anti tag coimmunoprecipitation 12150926 physical association X 2 Q8N122 Q13541 pull down 12150926 physical association X 2 Q8N122 Q9BVC4 anti tag coimmunoprecipitation 12408816 physical association X 2 Q8N122 Q9BVC4 anti tag coimmunoprecipitation 12408816 physical association X 2 Q8N122 Q13541 far western blotting 18337751 physical association X 2 Q8N122 P63101 coimmunoprecipitation 18439900 association X 2 Q8N122 P63101 coimmunoprecipitation 18439900 association X 2 Q8N122 Q9P2J5 fluorescence microscopy 22424946 association X 2 Q8N122 Q96R06 anti bait coimmunoprecipitation 23953116 physical association X 2 Q8N122 Q96R06 proximity ligation assay 23953116 physical association X 2 Q8N122 Q96R06 anti bait coimmunoprecipitation 23953116 physical association X 2 Q8N122 P62820 proximity ligation assay 25446900 physical association X 2 Q8N122 P62820 anti tag coimmunoprecipitation 25446900 physical association X 2 Q8N122 P62820 anti tag coimmunoprecipitation 25446900 physical association X 2 Q8N122 anti bait coimmunoprecipitation 25446900 association C 3 Q8N122 anti bait coimmunoprecipitation 25446900 association C 3 Q8N122 anti bait coimmunoprecipitation 19446321 physical association C 4 Q8N122 anti bait coimmunoprecipitation 19446321 physical association C 4 Q8N122 anti tag coimmunoprecipitation 19446321 physical association C 4 Q8N122 anti bait coimmunoprecipitation 19446321 physical association C 4 Q8N122 anti tag coimmunoprecipitation 20562859 physical association C 6 Q8N122 anti bait coimmunoprecipitation 22424946 association C 3 Q8N122 anti tag coimmunoprecipitation 25561175 association C 14 Q8N122 anti tag coimmunoprecipitation 24036451 association C 3 Q8N122 anti tag coimmunoprecipitation 17565979 association C 4 Q8N122 anti bait coimmunoprecipitation 19875983 association C 5 Q8N122 anti bait coimmunoprecipitation 19446321 association C 3 Q8N122 anti bait coimmunoprecipitation 19446321 physical association C 3 Q8N122 anti bait coimmunoprecipitation 21471201 association C 3 Q8N122 anti tag coimmunoprecipitation 12150926 association C 3 Q8N122 anti tag coimmunoprecipitation 21903422 association C 18 Q8N122 cross-linking study 22980980 association C 3 Q8N122 anti tag coimmunoprecipitation 19446321 physical association C 3 Q8N122 anti bait coimmunoprecipitation 23953116 association C 4 Q8N122 anti tag coimmunoprecipitation 25561175 association C 6 Q8N122 cross-linking study 22980980 association C 3 Q8N122 anti tag coimmunoprecipitation 25561175 association C 7 P13473 Q8N122 proximity ligation assay 23953116 physical association X 2 Q13283 Q8N122 anti bait coimmunoprecipitation 23953116 physical association X 2 Q13283 Q8N122 proximity ligation assay 23953116 physical association X 2 Q9HB90 Q8N122 proximity ligation assay 25446900 physical association X 2 Q8N122 Q9JLN9 anti tag coimmunoprecipitation 12150926 physical association X 2 Q8N122 Q9JLN9 anti tag coimmunoprecipitation 12150926 physical association X 2 Q8N122 P67999 pull down 12150926 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 12150926 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 12150926 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 12150926 physical association X 2 Q8N122 P42345 anti tag coimmunoprecipitation 12408816 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 19619545 association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 19875983 physical association X 2 Q8N122 Q8TCU6 anti tag coimmunoprecipitation 21339740 physical association X 2 Q8N122 A0A024QZQ1 anti bait coimmunoprecipitation 21471201 physical association X 2 Q8N122 A0A024QZQ1 anti bait coimmunoprecipitation 21471201 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 22424946 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 23953116 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 23953116 physical association X 2 Q8N122 P42345 proximity ligation assay 23953116 physical association X 2 Q8N122 Q14152 proximity ligation assay 23953116 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 24375676 physical association X 2 Q8N122 P42345 anti bait coimmunoprecipitation 25446900 physical association X 2 Q8N122 A0A090N900 proximity ligation assay 25446900 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B PLD2 RPTOR MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 16837165 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_32718|BIOGRID_102620|HPRD_39972 -|prey|- -|bait|- YWHAQ RPTOR MI:0415(enzymatic study) 18439900 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_210994 bait prey RPTOR EIF3C MI:0004(affinity chromatography technology) 16286006 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_102835 prey bait RPTOR ICK MI:0415(enzymatic study)|MI:0415(enzymatic study) 22356909 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_211615|BIOGRID_211614 prey|prey bait|bait EIF3A RPTOR MI:0006(anti bait coimmunoprecipitation) 23953116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_130627 neutral component neutral component CCNB1 RPTOR MI:0004(affinity chromatography technology) 20169205 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_211763 prey bait UBD RPTOR MI:0004(affinity chromatography technology) 22797925 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_226411 bait prey RAP2A RPTOR MI:0004(affinity chromatography technology) 18497260 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_217577 bait prey MAPK3 RPTOR MI:0415(enzymatic study)|MI:0415(enzymatic study) 21071439 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_212856|BIOGRID_212858 bait|bait prey|prey RPTOR MLST8 MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 12408816,12718876,16798736,17565979,20169205,20562859,21321085 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid) HPRD_14122|UniProt_70210|BIOGRID_260013|BIOGRID_211765|BIOGRID_212703|BIOGRID_125321|UniProt_70209|BIOGRID_255938 -|prey|bait|bait|bait|prey|bait|bait -|bait|prey|prey|prey|bait|prey|prey RPTOR USP9X MI:0415(enzymatic study) 22544753 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201621 prey bait PDIA3 RPTOR MI:0018(two hybrid)|MI:0018(two hybrid) 21321085 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_260015|BIOGRID_260011 bait|prey prey|bait RRAGA RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 18497260,21816923,23184942 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_217578|BIOGRID_141615|BIOGRID_261524|BIOGRID_141618 bait|prey|bait|bait prey|bait|prey|prey UBC RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,21963094,23297343 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_171301|BIOGRID_264236|BIOGRID_180475|BIOGRID_176132|BIOGRID_248633 bait|bait|bait|bait|prey prey|prey|prey|prey|bait RPTOR AMBRA1 MI:0004(affinity chromatography technology) 23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_281068 bait prey ULK1 RPTOR MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 21460630 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_213858|BIOGRID_213862|BIOGRID_213861 bait|prey|bait prey|bait|prey MTOR RPTOR MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0415(enzymatic study)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0007(anti tag coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo)|MI:0492(in vitro)|MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation) 12150925,12150926,12408816,12604610,12665511,12718876,12719976,12747827,15066126,15268862,15459249,15467718,16183647,16286006,16354680,16603397,16631613,16798736,16837165,16847060,16919458,16962653,17043309,17386266,17461779,17565979,18505677,18722121,18955708,19145465,19446321,19619545,19875983,20169205,20427287,21045808,21071439,21177249,21321085,22258093,22356909,22424946,22493283,22544753,23297343,23911927,23953116,24036451 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|-|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|-|-|-|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|-|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(biogrid)|MI:0468(hprd)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0465(dip)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0468(hprd)|MI:0468(hprd)|MI:0468(hprd)|(intact)|(intact)|(intact)|(intact)|MI:0468(hprd)|(intact)|(intact)|(intact) UniProt_130616|UniProt_130614|MINT_45558|MINT_76026|UniProt_103767|UniProt_166210|UniProt_90577|UniProt_130618|UniProt_130621|MINT_42009|BIOGRID_123207|UniProt_130628|UniProt_130622|BIOGRID_155139|UniProt_130620|BIOGRID_211972|HPRD_32596|UniProt_101740|BIOGRID_244413|BIOGRID_227345|UniProt_103770|BIOGRID_260017|BIOGRID_216099|BIOGRID_260012|BIOGRID_211224|BIOGRID_201614|BIOGRID_102815|BIOGRID_102816|BIOGRID_102813|BIOGRID_102814|BIOGRID_102819|BIOGRID_102817|BIOGRID_102818|BIOGRID_255936|BIOGRID_284790|BIOGRID_215071|BIOGRID_211764|BIOGRID_81669|BIOGRID_81668|BIOGRID_259595|BIOGRID_215073|BIOGRID_102812|BIOGRID_248618|BIOGRID_211619|BIOGRID_211618|BIOGRID_150511|BIOGRID_211617|BIOGRID_211616|BIOGRID_155051|MINT_45561|MINT_71999|BIOGRID_270516|BIOGRID_248617|BIOGRID_102828|BIOGRID_85948|BIOGRID_85947|UniProt_70251|UniProt_70250|BIOGRID_102824|BIOGRID_102825|BIOGRID_102826|BIOGRID_102827|BIOGRID_102590|BIOGRID_102820|BIOGRID_102821|BIOGRID_213422|BIOGRID_102822|BIOGRID_102823|BIOGRID_102586|BIOGRID_102585|BIOGRID_102588|BIOGRID_244409|DIP_54218|BIOGRID_102587|BIOGRID_102589|BIOGRID_253613|BIOGRID_212860|UniProt_122852|MINT_76029|UniProt_70244|UniProt_70207|BIOGRID_270508|BIOGRID_252211|BIOGRID_211800|BIOGRID_214372|BIOGRID_85951|BIOGRID_102583|BIOGRID_252215|BIOGRID_102584|BIOGRID_211804|UniProt_111677|UniProt_111681|UniProt_173750|UniProt_89570|UniProt_130617|UniProt_130615|HPRD_39859|HPRD_39940|HPRD_39956|UniProt_130619|UniProt_100525|UniProt_100527|UniProt_130613|HPRD_39972|UniProt_122853|UniProt_122855|UniProt_131874 prey|prey|bait|bait|bait|prey|prey|prey|bait|bait|bait|neutral component|prey|bait|bait|bait|-|bait|prey|prey|prey|bait|prey|prey|prey|bait|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|prey|prey|bait|bait|bait|bait|prey|prey|bait|bait|bait|prey|prey|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|prey|prey|prey|bait|-|prey|prey|bait|prey|bait|bait|bait|prey|prey|bait|prey|prey|prey|prey|prey|prey|bait|prey|neutral component|neutral component|bait|prey|prey|-|-|-|prey|prey|prey|prey|-|bait|prey|prey bait|bait|prey|prey|prey|bait|bait|bait|prey|prey|prey|neutral component|bait|prey|prey|prey|-|prey|bait|bait|bait|prey|bait|bait|bait|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|bait|bait|prey|prey|prey|prey|bait|bait|prey|prey|prey|bait|bait|bait|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|bait|bait|bait|prey|-|bait|bait|prey|bait|prey|bait|prey|bait|bait|prey|bait|bait|bait|bait|bait|bait|prey|bait|neutral component|neutral component|prey|bait|bait|-|-|-|bait|bait|bait|bait|-|prey|prey|bait DDB1 RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23297343 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_248623|BIOGRID_248628 prey|bait bait|prey MAPK8 RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22493283 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_211223|BIOGRID_211222 prey|bait bait|prey EIF4E RPTOR MI:0004(affinity chromatography technology) 16798736 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_212707 prey bait EIF4EBP1 RPTOR MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0492(in vitro)|MI:0493(in vivo)|MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0401(biochemical)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)|MI:0415(enzymatic study)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 12150926,12604610,12665511,12747827,12912989,15767663,16798736,16824195,16837165,17386266,17502379,18337751,18722121,21071439,22493283 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|-|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0468(hprd)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid) UniProt_162213|UniProt_181045|UniProt_70247|UniProt_162222|UniProt_70258|UniProt_181036|HPRD_39940|HPRD_39956|MINT_36084|BIOGRID_216307|UniProt_70256|MINT_65200|BIOGRID_251990|BIOGRID_102806|BIOGRID_251992|UniProt_181043|HPRD_32586|BIOGRID_102808|BIOGRID_102536|BIOGRID_102538|UniProt_162220|BIOGRID_102810|BIOGRID_218380|BIOGRID_212706|UniProt_96343|BIOGRID_212862|UniProt_181038|UniProt_70249|BIOGRID_211226|BIOGRID_216098|BIOGRID_245139|BIOGRID_102805|BIOGRID_218379|BIOGRID_211798|BIOGRID_102807|BIOGRID_102809|BIOGRID_102537|UniProt_162215|BIOGRID_102811 prey|bait|prey|bait|bait|prey|-|-|bait|prey|bait|bait|prey|bait|bait|bait|-|bait|prey|prey|bait|bait|bait|prey|bait|prey|prey|prey|prey|prey|bait|bait|bait|prey|bait|bait|prey|prey|bait bait|prey|bait|prey|prey|bait|-|-|prey|bait|prey|prey|bait|prey|prey|prey|-|prey|bait|bait|prey|prey|prey|bait|prey|bait|bait|bait|bait|bait|prey|prey|prey|bait|prey|prey|bait|bait|prey FKBP1A RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15268862,15467718 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_81672|BIOGRID_85953 bait|bait prey|prey RPS6KA1 RPTOR MI:0415(enzymatic study) 18722121 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_216097 bait prey AMPKa2 RPTOR MI:0415(enzymatic study) 18439900 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_210993 bait prey AKT1 RPTOR MI:0004(affinity chromatography technology) 21339740 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_257463 bait prey LAMP2 RPTOR MI:0006(anti bait coimmunoprecipitation) 23953116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_130632 neutral component neutral component RPS6 RPTOR MI:0006(anti bait coimmunoprecipitation)|MI:0415(enzymatic study) 21045808 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_111677|BIOGRID_155232 prey|prey bait|bait IQGAP1 RPTOR MI:0004(affinity chromatography technology) 22328503 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_182609 bait prey RPTOR IRS2 MI:0004(affinity chromatography technology) 19561084 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_216430 prey bait RPTOR TRAF6 MI:0004(affinity chromatography technology) 23911927 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284783 prey bait RICTOR RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19145465,21045808 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_214373|BIOGRID_214375|UniProt_111681|UniProt_173750 prey|bait|neutral component|neutral component bait|prey|neutral component|neutral component HSPA4 RPTOR MI:0004(affinity chromatography technology) 16962653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_213415 prey bait G3BP1 RPTOR MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 23953116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_130616|UniProt_130613|UniProt_130629|UniProt_130624 prey|prey|neutral component|prey bait|bait|neutral component|bait RPTOR LARS MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down) 22424946 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_255956|BIOGRID_255948|UniProt_122854|UniProt_122851 bait|prey|neutral component|bait prey|bait|neutral component|prey SQSTM1 RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21981924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_211184|BIOGRID_211198 bait|prey prey|bait TIRAP RPTOR MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_155616|UniProt_115749|UniProt_172491 bait|bait|bait prey|prey|prey RPTOR MARK4 MI:0415(enzymatic study) 23184942 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_261522 prey bait CUL4B RPTOR MI:0004(affinity chromatography technology) 23297343 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248620 prey bait RRAGB RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18497260,21981924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_217588|BIOGRID_211195|BIOGRID_217579 bait|prey|bait prey|bait|prey RPTOR AKT1S1 MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 17386266,19446321,20169205,23953116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_211799|BIOGRID_211766|BIOGRID_211805|BIOGRID_252207|UniProt_130618|UniProt_130617|UniProt_130615|UniProt_100520 bait|bait|bait|prey|bait|bait|bait|prey prey|prey|prey|bait|prey|prey|prey|bait RHEB RPTOR MI:0096(pull down)|MI:0493(in vivo)|MI:0096(pull down) 15854902,16631613 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_102831|HPRD_32737|BIOGRID_102830 bait|-|bait prey|-|prey RPTOR SIRT1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 21471201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid)|(intact) UniProt_111923|UniProt_111925|BIOGRID_253675|BIOGRID_253677|UniProt_111922 prey|bait|prey|bait|prey bait|prey|bait|prey|bait IRS1 RPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 16354680,19561084 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_212025|BIOGRID_216428|BIOGRID_216427|BIOGRID_216425|HPRD_32731 prey|bait|bait|prey|- bait|prey|prey|bait|- CUL4A RPTOR MI:0004(affinity chromatography technology) 23297343 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248619 prey bait MAPK1 RPTOR MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 21071439,21325048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_213810|BIOGRID_212857|BIOGRID_212859 bait|bait|bait prey|prey|prey RPTOR SPAG5 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 23953116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_130614|UniProt_130618|UniProt_130617|UniProt_130615|UniProt_130630|UniProt_130623|UniProt_130633|UniProt_130619|UniProt_130613 bait|bait|bait|bait|neutral component|bait|bait|bait|bait prey|prey|prey|prey|neutral component|prey|prey|prey|prey HIF1A RPTOR MI:0004(affinity chromatography technology) 17502379 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_245138 bait prey RPTOR RRAGD MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18497260,22424946 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid) UniProt_122835|UniProt_122856|UniProt_122851|BIOGRID_255957|BIOGRID_217586|BIOGRID_255951|BIOGRID_217581 prey|prey|bait|bait|prey|prey|prey bait|bait|prey|prey|bait|bait|bait EIF3B RPTOR MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0493(in vivo) 16286006,21045808 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_155052|BIOGRID_102834|BIOGRID_155050|HPRD_39859 prey|bait|bait|- bait|prey|prey|- RPS6KB1 RPTOR MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0492(in vitro)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 12150926,12604610,15809305,16837165,17386266,21071439,22493283,23184942 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_102680|BIOGRID_211789|HPRD_32597|BIOGRID_212861|BIOGRID_261544|BIOGRID_102833|BIOGRID_211227|BIOGRID_102679|BIOGRID_102832|BIOGRID_217989 prey|prey|-|prey|prey|bait|prey|prey|bait|bait bait|bait|-|bait|bait|prey|bait|bait|prey|prey RPTOR RRAGC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18497260,21816923,21981924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_141616|BIOGRID_211197|BIOGRID_217580 bait|prey|prey prey|bait|bait PDK1 RPTOR MI:0096(pull down) 12150926 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_102829 bait prey RPTOR DEPTOR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19446321,20169205 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_211767|BIOGRID_252209|BIOGRID_252216|UniProt_100523|UniProt_100522|UniProt_100521|UniProt_100519|UniProt_100525|UniProt_100527 bait|prey|bait|prey|bait|prey|prey|bait|bait prey|bait|prey|prey|prey|prey|bait|prey|prey RPTOR PREX1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17565979,21339740 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_166210|UniProt_90577|UniProt_112726|BIOGRID_257465|BIOGRID_255937 bait|bait|prey|prey|bait prey|prey|bait|bait|prey AMPKa1 RPTOR MI:0415(enzymatic study) 18439900 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_210992 bait prey UCHL1 RPTOR MI:0004(affinity chromatography technology) 23297343 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248631 prey bait

PPI - HINT Gene A Gene B PMID Method Quality IKBKB RPTOR 18519641,23872070 0004,0004 LC ULK1 RPTOR 21460630,25686248,21460630 0004,0004,0415 LC BAG3 RPTOR 26186194 0004 HT NT5E RPTOR 26186194 0004 HT RPS6KB1 RPTOR 12150926,15809305,16837165,21071439,12604610 0004,0096,0004,0004,0004 LC IRS1 RPTOR 19561084,16354680,19561084 0096,0004,0004 LC MTOR RPTOR 15467718,21177249,18676370,12718876,24036451,12665511,15809305,22544753,18505677,17461779,12747827,22493283,19619545,16919458,16631613,12150926,17043309,25007995,18519641,23872070,22356909,15268862,18614546,18030348,23263282,17386266,18955708,16603397,22424946,24375676,21045808,19446321,12150925,21045808,12718876,16603397,16847060,12150925,17565979,25332233,16962653,16798736,12719976,19875983,25446900,23911927,24337580,17565979,20169205,18722121,18570873,12150925,17277771,12150926,17461779,17043309,24516643,18519641,15066126,12408816,15268862,18030348,18570873,15467718,24403073,12408816,22356909,16183647,19145465,23953116,18955708,20381137,16847060,21045808,20427287,22356909,15459249,25446900,19619545,16837165,19145465,17277771,20381137,17461779,19875983,15066126,23953116,17599906,16962653,16919458,21321085,19114562,12150926,17043309,12150926,17604271,23297343,19446321,21071439,19114562,22258093 0004,0004,0007,0007,0006,0004,0007,0004,0004,0004,0004,0004,0006,0007,0004,0007,0007,0004,0004,0004,0415,0007,0007,0004,0006,0004,0004,0004,0006,0006,0006,0004,0019,0029,0004,0007,0007,0004,0007,0004,0007,0004,0004,0006,0006,0004,0004,0004,0004,0004,0004,0007,0004,0004,0006,0401,0004,0401,0004,0007,0004,0007,0007,0007,0004,0004,0401,0004,0004,0006,0006,0428,0004,0004,0004,0004,0004,0004,0004,0004,0007,0007,0004,0007,0004,0007,0813,0007,0004,0004,0004,0004,0006,0004,0019,0007,0004,0006,0004,0007,0004 LC EIF3B RPTOR 16286006,21045808,16286006 0004,0004,0007 LC FKBP1A RPTOR 15268862,15467718 0004,0004 LC SCAP RPTOR 26344197 0401 HT SQSTM1 RPTOR 26279575,21981924 0004,0004 LC EIF4EBP1 RPTOR 12747827,24403073,12912989,12665511,12912989,12747827,16824195,12912989,12150926,15767663,12604610,17502379,16798736,12150926,21071439,16824195,17502379,24403073,12604610,18722121,12150926,17502379,16837165 0007,0096,0096,0004,0047,0004,0004,0004,0096,0004,0007,0096,0004,0007,0004,0007,0007,0004,0004,0004,0004,0004,0004 LC PDK1 RPTOR 24516643,12150926 0004,0004 LC RHEB RPTOR 15854902,25446900,25446900,17470430,24337580,15878852,15854902 0004,0813,0428,0096,0004,0007,0096 LC RRAGB RPTOR 18497260,24337580,24337580,18497260,21981924,18497260 0096,0004,0096,0007,0004,0004 LC RICTOR RPTOR 19446321,19145465 0006,0004 LC RRAGA RPTOR 24337580,21816923,26186194,18497260,21816923,18497260,25561175,23184942 0096,0096,0004,0007,0004,0004,0007,0004 LC,HT RPTOR RPTOR 22424946,24403073 0004,0004 LC RPTOR DEPTOR 19446321,20169205,19446321,19446321 0006,0004,0007,0004 LC RPTOR PREX1 17565979,21339740,21339740,17565979 0004,0004,0007,0007 LC RPTOR AKT1S1 17604271,18215133,18570873,23953116,17277771,17604271,18030348,19446321,18030348,17517883,17386266,19446321,17517883,20169205 0007,0007,0004,0006,0004,0047,0007,0007,0004,0007,0004,0004,0096,0004 LC RPTOR FAF2 26186194,26389662 0004,0004 HT,LC RPTOR TXNDC15 26186194 0004 HT RPTOR MLST8 12408816,21321085,16798736,18030348,20562859,20562859,17565979,12408816,20169205,24403073 0004,0004,0004,0004,0007,0004,0004,0007,0004,0004 LC,HT RPTOR RRAGC 21816923,25446900,25446900,21981924,18497260,24337580,18497260,25561175 0096,0813,0428,0004,0007,0004,0004,0007 LC RPTOR RRAGD 18497260,24337580,22424946,22424946,18497260,22424946,18497260 0096,0004,0004,0006,0007,0007,0004 LC BAG3 RPTOR 26186194 0004 HT NT5E RPTOR 26186194 0004 HT SCAP RPTOR 26344197 0401 HT RRAGA RPTOR 26186194 0004 HT RPTOR FAF2 26186194 0004 HT RPTOR TXNDC15 26186194 0004 HT RPTOR MLST8 20562859,20562859 0007,0004 HT IKBKB RPTOR 18519641,23872070 0004,0004 LC ULK1 RPTOR 21460630,25686248,21460630 0004,0004,0415 LC RPS6KB1 RPTOR 12150926,15809305,16837165,21071439,12604610 0004,0096,0004,0004,0004 LC IRS1 RPTOR 19561084,16354680,19561084 0096,0004,0004 LC MTOR RPTOR 15467718,21177249,18676370,12718876,24036451,12665511,15809305,22544753,18505677,17461779,12747827,22493283,19619545,16919458,16631613,12150926,17043309,25007995,18519641,23872070,22356909,15268862,18614546,18030348,23263282,17386266,18955708,16603397,22424946,24375676,21045808,19446321,12150925,21045808,12718876,16603397,16847060,12150925,17565979,25332233,16962653,16798736,12719976,19875983,25446900,23911927,24337580,17565979,20169205,18722121,18570873,12150925,17277771,12150926,17461779,17043309,24516643,18519641,15066126,12408816,15268862,18030348,18570873,15467718,24403073,12408816,22356909,16183647,19145465,23953116,18955708,20381137,16847060,21045808,20427287,22356909,15459249,25446900,19619545,16837165,19145465,17277771,20381137,17461779,19875983,15066126,23953116,17599906,16962653,16919458,21321085,19114562,12150926,17043309,12150926,17604271,23297343,19446321,21071439,19114562,22258093 0004,0004,0007,0007,0006,0004,0007,0004,0004,0004,0004,0004,0006,0007,0004,0007,0007,0004,0004,0004,0415,0007,0007,0004,0006,0004,0004,0004,0006,0006,0006,0004,0019,0029,0004,0007,0007,0004,0007,0004,0007,0004,0004,0006,0006,0004,0004,0004,0004,0004,0004,0007,0004,0004,0006,0401,0004,0401,0004,0007,0004,0007,0007,0007,0004,0004,0401,0004,0004,0006,0006,0428,0004,0004,0004,0004,0004,0004,0004,0004,0007,0007,0004,0007,0004,0007,0813,0007,0004,0004,0004,0004,0006,0004,0019,0007,0004,0006,0004,0007,0004 LC EIF3B RPTOR 16286006,21045808,16286006 0004,0004,0007 LC FKBP1A RPTOR 15268862,15467718 0004,0004 LC SQSTM1 RPTOR 26279575,21981924 0004,0004 LC EIF4EBP1 RPTOR 12747827,24403073,12912989,12665511,12912989,12747827,16824195,12912989,12150926,15767663,12604610,17502379,16798736,12150926,21071439,16824195,17502379,24403073,12604610,18722121,12150926,17502379,16837165 0007,0096,0096,0004,0047,0004,0004,0004,0096,0004,0007,0096,0004,0007,0004,0007,0007,0004,0004,0004,0004,0004,0004 LC PDK1 RPTOR 24516643,12150926 0004,0004 LC RHEB RPTOR 15854902,25446900,25446900,17470430,24337580,15878852,15854902 0004,0813,0428,0096,0004,0007,0096 LC RRAGB RPTOR 18497260,24337580,24337580,18497260,21981924,18497260 0096,0004,0096,0007,0004,0004 LC RICTOR RPTOR 19446321,19145465 0006,0004 LC RRAGA RPTOR 24337580,21816923,18497260,21816923,18497260,25561175,23184942 0096,0096,0007,0004,0004,0007,0004 LC RPTOR RPTOR 22424946,24403073 0004,0004 LC RPTOR DEPTOR 19446321,20169205,19446321,19446321 0006,0004,0007,0004 LC RPTOR PREX1 17565979,21339740,21339740,17565979 0004,0004,0007,0007 LC RPTOR AKT1S1 17604271,18215133,18570873,23953116,17277771,17604271,18030348,19446321,18030348,17517883,17386266,19446321,17517883,20169205 0007,0007,0004,0006,0004,0047,0007,0007,0004,0007,0004,0004,0096,0004 LC RPTOR FAF2 26389662 0004 LC RPTOR MLST8 12408816,21321085,16798736,18030348,17565979,12408816,20169205,24403073 0004,0004,0004,0004,0004,0007,0004,0004 LC RPTOR RRAGC 21816923,25446900,25446900,21981924,18497260,24337580,18497260,25561175 0096,0813,0428,0004,0007,0004,0004,0007 LC RPTOR RRAGD 18497260,24337580,22424946,22424946,18497260,22424946,18497260 0096,0004,0004,0006,0007,0007,0004 LC LAMTOR5 RPTOR 22980980 0030 LC ULK1 RPTOR 21460630,21460630 0004,0415 LC RPS6KB1 RPTOR 22493283,23184942,19402821 0415,0415,0415 LC MAPK3 RPTOR 21071439,21071439 0096,0415 LC MAPK1 RPTOR 21071439,21325048,21071439 0096,0415,0415 LC MTOR RPTOR 15718470,12150926,17043309,18519641,22356909,21045808,12150925,21045808,12150925,12150925,12150926,17043309,18519641,16354680,22356909,21045808,21614075,22356909,12150926,17043309,12150926 0019,0007,0007,0004,0415,0006,0019,0029,0004,0007,0004,0401,0401,0415,0401,0004,0892,0004,0006,0004,0019 LC PRKAA2 RPTOR 18439900 0415 LC LAMTOR4 RPTOR 22980980 0030 LC SCAP RPTOR 26344197 0401 LC PRKAA1 RPTOR 18439900 0415 LC EIF4EBP1 RPTOR 12912989,12912989,12912989,22493283,18337751,18955708,19272448,18337751 0096,0047,0004,0415,0047,0415,0047,0415 LC RPS6KA1 RPTOR 18722121 0415 LC LAMTOR1 RPTOR 22980980 0030 LC RPTOR AKT1S1 17604271,17604271 0007,0047 LC RPTOR MARK4 23184942 0415 LC RPTOR LARS 22424946,22424946,22424946,22424946 0006,0004,0007,0416 LC RPTOR ICK 22356909,22356909 0415,0401 LC RPTOR LAMTOR2 22980980 0030 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8N122 P59768 RPTOR GNG2 0.21 24462769 Q8N122 O14920 RPTOR IKBKB 0.376 23872070,18519641 Q8N122 O14939 RPTOR PLD2 0.21 16837165 Q8N122 O15075 RPTOR DCLK1 0.126 unassigned1312 Q8N122 O15111 RPTOR CHUK 0.21 18519641 Q8N122 O60307 RPTOR MAST3 0.126 unassigned1312 Q8N122 O60573 RPTOR EIF4E2 0.126 unassigned1312 Q8N122 O75044 RPTOR SRGAP2 0.126 unassigned1312 Q8N122 O75420 RPTOR GIGYF1 0.126 unassigned1312 Q8N122 O95817 RPTOR BAG3 0.126 26186194 Q8N122 P06730 RPTOR EIF4E 0.21 16798736 Q8N122 P09936 RPTOR UCHL1 0.21 23297343 Q8N122 P14635 RPTOR CCNB1 0.21 20169205 Q8N122 P34932 RPTOR HSPA4 0.21 16962653 Q8N122 P55884 RPTOR EIF3B 0.396 16286006,21045808 Q8N122 P63101 RPTOR YWHAZ 0.21 18439900 Q8N122 Q13283 RPTOR G3BP1 0.507 23953116 Q8N122 Q13501 RPTOR SQSTM1 0.507 21981924,26279575 Q8N122 Q13542 RPTOR EIF4EBP2 0.21 20347422 Q8N122 Q13615 RPTOR MTMR3 0.507 26787466 Q8N122 Q13619 RPTOR CUL4A 0.21 23297343 Q8N122 Q13620 RPTOR CUL4B 0.21 23297343 Q8N122 Q14966 RPTOR ZNF638 0.126 unassigned1312 Q8N122 Q15118 RPTOR PDK1 0.507 12150926,24516643 Q8N122 Q15382 RPTOR RHEB 0.702 25446900,15854902,24337580 Q8N122 Q5TCZ1 RPTOR SH3PXD2A 0.126 unassigned1312 Q8N122 Q5VZ89 RPTOR DENND4C 0.126 unassigned1312 Q8N122 Q7L523 RPTOR RRAGA 0.74 26186194,25561175,21816923,18497260,23184942 Q8N122 Q8IVT5 RPTOR KSR1 0.126 unassigned1312 Q8TEH3 Q8N122 DENND1A RPTOR 0.126 unassigned1312 Q9BQK8 Q8N122 LPIN3 RPTOR 0.126 unassigned1312 Q9BST9 Q8N122 RTKN RPTOR 0.126 unassigned1312 Q9C0C7 Q8N122 AMBRA1 RPTOR 0.21 23524951 Q9DCJ1 Q8N122 MLST8 RPTOR 0.21 17565979 Q9NRR6 Q8N122 INPP5E RPTOR 0.126 unassigned1312 Q9NWS0 Q8N122 PIH1D1 RPTOR 0.376 24036451 Q9P244 Q8N122 LRFN1 RPTOR 0.126 unassigned1312 Q9UHB6 Q8N122 LIMA1 RPTOR 0.126 unassigned1312 Q9ULJ3 Q8N122 ZBTB21 RPTOR 0.126 unassigned1312 Q9ULR3 Q8N122 PPM1H RPTOR 0.126 unassigned1312 Q9Y3M2 Q8N122 CBY1 RPTOR 0.126 unassigned1312 Q9Y597 Q8N122 KCTD3 RPTOR 0.126 unassigned1312 Q9Y603 Q8N122 ETV7 RPTOR 0.21 24036451 Q9Y6K9 Q8N122 IKBKG RPTOR 0.21 18519641 Q9HCE1 Q8N122 MOV10 RPTOR 0.126 22658674 Q8N122 O60260 RPTOR PARK2 0.21 25007995 Q9NQT8 Q8N122 KIF13B RPTOR 0.126 unassigned1312 Q8TCU6 Q8N122 PREX1 RPTOR 0.507 17565979,21339740 Q9WVC6 Q8N122 SGK1 RPTOR 0.309 18570873 Q9Y4K3 Q8N122 TRAF6 RPTOR 0.21 23911927 Q9Y4H2 Q8N122 IRS2 RPTOR 0.309 19561084 Q8N122 Q6PJG6 RPTOR BRAT1 0.21 25657994 Q8N122 O43166 RPTOR SIPA1L1 0.126 unassigned1312 Q8N122 Q6P5F9 RPTOR XPO1 0.126 26673895 Q8N122 P13473 RPTOR LAMP2 0.21 23953116 Q8N122 O95644 RPTOR NFATC1 0.126 27637333 Q8N122 P04629 RPTOR NTRK1 0.126 25921289 Q8N122 P35568 RPTOR IRS1 0.659 19561084,16354680 Q8N122 O75385 RPTOR ULK1 0.731 25686248,21460630 Q8N122 Q8N122 RPTOR RPTOR 0.416 22424946,24403073 Q8N122 P67999 RPTOR RPS6KB1 0.376 12150926 Q8N122 P62753 RPTOR RPS6 0.236 21045808 Q8N122 Q6R327 RPTOR RICTOR 0.61 19446321,19145465 Q8N122 Q5VZM2 RPTOR RRAGB 0.731 21981924,18497260,24337580 Q921J2 Q8N122 RHEB RPTOR 0.454 16631613 Q9P2J5 Q8N122 LARS RPTOR 0.692 22424946 Q9JLN9 Q8N122 MTOR RPTOR 0.692 12150926,18235224,24036451 Q9NQL2 Q8N122 RRAGD RPTOR 0.787 22424946,18497260 Q9UPZ9 Q8N122 ICK RPTOR 0.396 22356909 Q9Y2Q5 Q8N122 LAMTOR2 RPTOR 0.236 22980980,20381137 Q96B36 Q8N122 AKT1S1 RPTOR 0.848 18030348,18570873,19446321,20169205,23953116,17277771,17386266 Q8N122 P80314 RPTOR CCT2 0.236 26496610 Q8N122 P80315 RPTOR CCT4 0.236 26496610 Q8N122 P27361 RPTOR MAPK3 0.523 21071439 Q8N122 Q0VGL1 RPTOR LAMTOR4 0.236 22980980,25561175 Q8N122 Q6IAA8 RPTOR LAMTOR1 0.236 22980980,25561175 Q8N122 O43504 RPTOR LAMTOR5 0.236 22980980,25561175 Q8N122 P62942 RPTOR FKBP1A 0.376 15467718,15268862 Q8N122 P58753 RPTOR TIRAP 0.236 21903422 Q8N122 P62820 RPTOR RAB1A 0.787 25446900 Q9HB90 Q8N122 RRAGC RPTOR 0.837 21981924,25446900,24337580,25561175,21816923,18497260 Q8TB45 Q8N122 DEPTOR RPTOR 0.808 19446321,20169205 Q8N122 P23443 RPTOR RPS6KB1 0.93 19402821,23184942,12150926,15809305,16837165,12604610,22493283,21071439 Q8N122 P28482 RPTOR MAPK1 0.671 21071439,21325048 Q9BVC4 Q8N122 MLST8 RPTOR 0.908 20562859,17565979,18030348,16798736,12408816,21321085,20169205,24403073 Q8N122 Q13541 RPTOR EIF4EBP1 1 16824195,12912989,18955708,12150926,16837165,12604610,12665511,21071439,18337751,16798736,17502379,18722121,12747827,15767663,24403073,22493283 Q8N122 P42345 RPTOR MTOR 1 17565979,23297343,21321085,16837165,12719976,17277771,18570873,23872070,16847060,15467718,19145465,22356909,12150926,12665511,25332233,21177249,15268862,24375676,19619545,16798736,16603397,20381137,22258093,20169205,24403073,18519641,23953116,15066126,17043309,22493283,17386266,16962653,15459249,16354680,25007995,18030348,20427287,19446321,23911927,19114562,16183647,22544753,24516643,12150925,18722121,12747827,16919458,25446900,21045808,24337580,18955708,17461779,18505677,12718876,21071439,22424946,19875983,24036451,16631613,12408816 Q93008 Q8N122 USP9X RPTOR 0.21 22544753 Q8N122 P30101 RPTOR PDIA3 0.376 21321085 Q96CS3 Q8N122 FAF2 RPTOR 0.236 26389662,26186194 Q96EB6 Q8N122 SIRT1 RPTOR 0.376 21471201 Q8N122 P31749 RPTOR AKT1 0.21 21339740 Q96J42 Q8N122 TXNDC15 RPTOR 0.126 26186194 Q96L34 Q8N122 MARK4 RPTOR 0.309 23184942 Q96QZ7 Q8N122 MAGI1 RPTOR 0.126 unassigned1312 Q96R06 Q8N122 SPAG5 RPTOR 0.507 23953116 Q96S53 Q8N122 TESK2 RPTOR 0.126 unassigned1312 Q8N122 P27348 RPTOR YWHAQ 0.21 18439900 Q99613 Q8N122 EIF3C RPTOR 0.21 16286006 Q9UBU9 Q8N122 NXF1 RPTOR 0.126 22658674 Q9P2M7 Q8N122 CGN RPTOR 0.126 unassigned1312 Q9UHA4 Q8N122 LAMTOR3 RPTOR 0.126 25561175 Q8N122 P45983 RPTOR MAPK8 0.376 22493283 Q8N122 P46940 RPTOR IQGAP1 0.21 22328503 Q8N122 B4URF7 RPTOR PB2 {ECO:0000256|RULEBASE:RU361246, ECO:0000313|EMBL:ACF54608.1} 0.126 unassigned1333 Q8N122 P62873 RPTOR GNB1 0.376 24462769 Q8N122 Q12789 RPTOR GTF3C1 0.376 20543138 Q8N122 Q14152 RPTOR EIF3A 0.21 23953116 Q8N122 Q14318 RPTOR FKBP8 0.21 17991864 Q8N122 P50406 RPTOR HTR6 0.21 23027611 Q8N122 Q15418 RPTOR RPS6KA1 0.309 18722121 Q8N122 Q13131 RPTOR PRKAA1 0.309 18439900 Q8N122 O00141 RPTOR SGK1 0.21 18570873 Q8N122 Q13469 RPTOR NFATC2 0.126 27637333 Q8N122 Q16531 RPTOR DDB1 0.376 23297343 Q8N122 P21589 RPTOR NT5E 0.126 26186194 Q8N122 Q16665 RPTOR HIF1A 0.21 17502379 Q8N122 Q3TLR7 RPTOR DTL 0.21 18235224 Q8N122 P54646 RPTOR PRKAA2 0.309 18439900

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SGK1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database WASL RPTOR MI:0362 inference MI:0461 interaction database FBP2 RPTOR MI:0362 inference MI:0461 interaction database IKBKB RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PLD2 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database XPO1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database SETD1A RPTOR MI:0362 inference MI:0461 interaction database CHUK RPTOR MI:0045 experimental interaction detection MI:0461 interaction database UBD RPTOR MI:0045 experimental interaction detection MI:0461 interaction database YY2 RPTOR MI:0362 inference MI:0461 interaction database TTI1 RPTOR MI:0362 inference MI:0461 interaction database LAMTOR5 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PRKAB2 RPTOR MI:0362 inference MI:1106 pathways database PARK2 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database EIF4EBP3 RPTOR MI:0362 inference MI:0461 interaction database DNAJA2 RPTOR MI:0362 inference MI:0461 interaction database ATG13 RPTOR MI:0362 inference MI:1106 pathways database RNF40 RPTOR MI:0362 inference MI:0461 interaction database CNOT3 RPTOR MI:0362 inference MI:0461 interaction database ULK1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MOCS3 RPTOR MI:0362 inference MI:0461 interaction database BAG3 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database ATP5B RPTOR MI:0362 inference MI:0461 interaction database EIF4E RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RHOC RPTOR MI:0362 inference MI:0461 interaction database HSP90AB1 RPTOR MI:0362 inference MI:0461 interaction database FBP1 RPTOR MI:0362 inference MI:0461 interaction database UCHL1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database UBC RPTOR MI:0045 experimental interaction detection MI:0461 interaction database HSPA1A RPTOR MI:0362 inference MI:0461 interaction database HSPA1B RPTOR MI:0362 inference MI:0461 interaction database RAP2A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database HSPD1 RPTOR MI:0362 inference MI:0461 interaction database HSPA8 RPTOR MI:0362 inference MI:0461 interaction database PABPC1 RPTOR MI:0362 inference MI:0461 interaction database LAMP2 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database CCNB1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database ATP6V1B1 RPTOR MI:0362 inference MI:0461 interaction database PPP3CB RPTOR MI:0362 inference MI:0461 interaction database HSPA6 RPTOR MI:0362 inference MI:0461 interaction database ATP6V1B2 RPTOR MI:0362 inference MI:0461 interaction database NT5E RPTOR MI:0045 experimental interaction detection MI:0461 interaction database TAF1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database RPS6KB1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database YY1 RPTOR MI:0362 inference MI:0461 interaction database ATP5A1 RPTOR MI:0362 inference MI:0461 interaction database FKBP2 RPTOR MI:0362 inference MI:0461 interaction database YWHAQ RPTOR MI:0045 experimental interaction detection MI:0461 interaction database MAPK3 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database MAPK1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PDIA3 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PPP2R1A RPTOR MI:0362 inference MI:0461 interaction database PPP2R1B RPTOR MI:0362 inference MI:0461 interaction database PPIF RPTOR MI:0362 inference MI:0461 interaction database DNAJA1 RPTOR MI:0362 inference MI:0461 interaction database AKT1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database YWHAB RPTOR MI:0362 inference MI:0461,MI:1106 interaction database,pathways database HSPA1L RPTOR MI:0362 inference MI:0461 interaction database HSPA4 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database IRS1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PPP1CC RPTOR MI:0362 inference MI:0461 interaction database MTOR RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MAPK8 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database IQGAP1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PPP3CC RPTOR MI:0362 inference MI:0461 interaction database PRIM2 RPTOR MI:0362 inference MI:0461 interaction database HTR6 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database CCT8 RPTOR MI:0362 inference MI:0461 interaction database CCT4 RPTOR MI:0362 inference MI:0461 interaction database GPC3 RPTOR MI:0362 inference MI:0461 interaction database CLTCL1 RPTOR MI:0362 inference MI:0461 interaction database PRKAG1 RPTOR MI:0362 inference MI:1106 pathways database PRKAA2 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA2 RPTOR MI:0362 inference MI:0461 interaction database NAP1L1 RPTOR MI:0362 inference MI:0461 interaction database EIF3B RPTOR MI:0045 experimental interaction detection MI:0461 interaction database TIRAP RPTOR MI:0045 experimental interaction detection MI:0461 interaction database GNG2 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database ACTB RPTOR MI:0362 inference MI:0461 interaction database EIF4A1 RPTOR MI:0362 inference MI:0461 interaction database RAP1B RPTOR MI:0045 experimental interaction detection MI:0461 interaction database RPL26 RPTOR MI:0362 inference MI:0461 interaction database RHOA RPTOR MI:0362 inference MI:0461 interaction database WDR5 RPTOR MI:0362 inference MI:0461 interaction database PPP1CA RPTOR MI:0362 inference MI:0461 interaction database PPP1CB RPTOR MI:0362 inference MI:0461 interaction database YWHAE RPTOR MI:0362 inference MI:0461 interaction database ACTA2 RPTOR MI:0362 inference MI:0461 interaction database RHOB RPTOR MI:0362 inference MI:0461 interaction database RPL23A RPTOR MI:0362 inference MI:0461 interaction database RPS6 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database RAB1A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database GNB1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PPIA RPTOR MI:0362 inference MI:0461 interaction database FKBP1A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ RPTOR MI:0362 inference MI:0461 interaction database ACTG1 RPTOR MI:0362 inference MI:0461 interaction database ACTG2 RPTOR MI:0362 inference MI:0461 interaction database ACTC1 RPTOR MI:0362 inference MI:0461 interaction database EEF1A1 RPTOR MI:0362 inference MI:0461 interaction database FKBP1B RPTOR MI:0362 inference MI:0461 interaction database ACTA1 RPTOR MI:0362 inference MI:0461 interaction database GPC5 RPTOR MI:0362 inference MI:0461 interaction database CCT2 RPTOR MI:0362 inference MI:0461 interaction database CLTC RPTOR MI:0362 inference MI:0461 interaction database HSF1 RPTOR MI:0362 inference MI:0461,MI:1106 interaction database,pathways database GALK2 RPTOR MI:0362 inference MI:0461 interaction database EEF1A2 RPTOR MI:0362 inference MI:0461 interaction database PPP3CA RPTOR MI:0362 inference MI:0461 interaction database LAMTOR4 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database GTF3C1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PRKAA1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database G3BP1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PABPC4 RPTOR MI:0362 inference MI:0461 interaction database TCIRG1 RPTOR MI:0362 inference MI:0461 interaction database SQSTM1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database EIF4EBP1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database EIF4EBP2 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database IQGAP2 RPTOR MI:0362 inference MI:0461 interaction database MTMR3 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database CUL4A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database CUL4B RPTOR MI:0045 experimental interaction detection MI:0461 interaction database EIF3A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database EIF4A2 RPTOR MI:0362 inference MI:0461 interaction database FKBP8 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database SEPT2 RPTOR MI:0362 inference MI:0461 interaction database PDK1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database STK38 RPTOR MI:0362 inference MI:0461 interaction database RHEB RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SF3B3 RPTOR MI:0362 inference MI:0461 interaction database RPS6KA1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PPP1R7 RPTOR MI:0362 inference MI:0461 interaction database NEDD8 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database SEPT7 RPTOR MI:0362 inference MI:0461 interaction database DDB1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database HIF1A RPTOR MI:0045 experimental interaction detection MI:0461 interaction database PABPC1L RPTOR MI:0362 inference MI:0461 interaction database PABPC1L2A RPTOR MI:0362 inference MI:0461 interaction database PPP4R3B RPTOR MI:0362 inference MI:0461 interaction database RNF20 RPTOR MI:0362 inference MI:0461 interaction database RRAGB RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database LAMTOR1 RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PPP4R3A RPTOR MI:0362 inference MI:0461 interaction database PRR5L RPTOR MI:0045 experimental interaction detection MI:0461 interaction database BRAT1 RPTOR MI:0045 experimental interaction detection MI:0461 interaction database RICTOR RPTOR MI:0045 experimental interaction detection MI:0461 interaction database RRAGA RPTOR MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database IQGAP3 RPTOR MI:0362 inference MI:0461 interaction database WDR5B RPTOR MI:0362 inference MI:0461 interaction database RPTOR SLC38A9 MI:0362 inference MI:0461 interaction database RPTOR LSM14A MI:0362 inference MI:0461 interaction database RPTOR DEPTOR MI:0045 experimental interaction detection MI:0461 interaction database RPTOR PREX1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR RB1CC1 MI:0362 inference MI:1106 pathways database RPTOR IPO4 MI:0362 inference MI:0461 interaction database RPTOR GTF3C2 MI:0362 inference MI:0461 interaction database RPTOR DNAJA4 MI:0362 inference MI:0461 interaction database RPTOR USP9X MI:0045 experimental interaction detection MI:0461 interaction database RPTOR ATP6V0A1 MI:0362 inference MI:0461 interaction database RPTOR AKT1S1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR FAF2 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR PABPC5 MI:0362 inference MI:0461 interaction database RPTOR SIRT1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR DNAJA3 MI:0362 inference MI:0461 interaction database RPTOR TXNDC15 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR MARK4 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR SPAG5 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR EIF3C MI:0045 experimental interaction detection MI:0461 interaction database RPTOR SEPT5 MI:0362 inference MI:0461 interaction database RPTOR NAP1L4 MI:0362 inference MI:0461 interaction database RPTOR MAPKAP1 MI:0362 inference MI:0461 interaction database RPTOR ATG101 MI:0362 inference MI:1106 pathways database RPTOR MLST8 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR LSM14B MI:0362 inference MI:0461 interaction database RPTOR AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR PABPC3 MI:0362 inference MI:0461 interaction database RPTOR DDX31 MI:0362 inference MI:0461 interaction database RPTOR RRAGC MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR ATP6V0A4 MI:0362 inference MI:0461 interaction database RPTOR MOV10 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR RRAGD MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR PFDN4 MI:0362 inference MI:0461 interaction database RPTOR ASF1B MI:0362 inference MI:0461 interaction database RPTOR PIH1D1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR DTL MI:0362 inference MI:0461 interaction database RPTOR LARS MI:0045 experimental interaction detection MI:0461 interaction database RPTOR RPS6KB2 MI:0362 inference MI:0461 interaction database RPTOR NXF1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR CNOT8 MI:0362 inference MI:0461 interaction database RPTOR PRKAG3 MI:0362 inference MI:1106 pathways database RPTOR PRKAG2 MI:0362 inference MI:1106 pathways database RPTOR LAMTOR3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR CNOT7 MI:0362 inference MI:0461 interaction database RPTOR FBXO9 MI:0362 inference MI:0461 interaction database RPTOR INO80 MI:0362 inference MI:0461 interaction database RPTOR NAP1L2 MI:0362 inference MI:0461 interaction database RPTOR PPIE MI:0362 inference MI:0461 interaction database RPTOR SETD1B MI:0362 inference MI:0461 interaction database RPTOR ICK MI:0045 experimental interaction detection MI:0461 interaction database RPTOR RUVBL2 MI:0362 inference MI:0461 interaction database RPTOR RUVBL1 MI:0362 inference MI:0461 interaction database RPTOR ASF1A MI:0362 inference MI:0461 interaction database RPTOR LAMTOR2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPTOR PRKAB1 MI:0362 inference MI:1106 pathways database RPTOR ATP6V0A2 MI:0362 inference MI:0461 interaction database RPTOR IRS2 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR TELO2 MI:0362 inference MI:0461 interaction database RPTOR ETV7 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR IKBKG MI:0045 experimental interaction detection MI:0461 interaction database