PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BAG3 SPAG16 23824909 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAPK13 SPAG16 20936779 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MEIG1 SPAG16 15328412, 21836163 hprd exp, ortho, pred P P GP P P P P G P P P P P GP SPAG6 SPAG16 12391165, 21836163 hprd exp, ortho, pred P P G G P G GP P G P GP GP GP G GP GP P P GP G SPAG16 STK36 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARL3 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPAG16 SPAG5 21836163 pred P GP G G GP GP G GP GP G GP GP GP GP GP GP GP GP G GP P P GP GP GP GP GP G CLPP SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G NME5 SPAG16 21836163 pred G G G G G G G G P G GP G GP G G G G G G G G G G G G GP G IFT88 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G G GP GP G G GP G PAFAH1B2 SPAG16 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G C21orf33 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CETN3 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G CRYAB SPAG16 21836163 pred GP G G G G GP G GP GP G GP G G G G G GP G G G GP G G GP G G G G G PAFAH1B1 SPAG16 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CLPX SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP G GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CRYAA SPAG16 21836163 pred G G G G G ODF1 SPAG16 21836163 pred P GP G G G G G GP GP G GP G G P G G GP G P GP GP P P GP G SPAG16 KATNB1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G EFHC1 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPAG16 NME8 21836163 pred P P P P P P P P P P P P P P SPAG16 DNAI1 21836163 pred G GP SPAG16 DNAH9 21836163 pred P G G G GP G P P G G GP G G G G G ODF2 SPAG16 21836163 pred P P P P P P P GP NME9 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP P G GP GP GP G GP P GP GP GP GP GP GP G SPAG16 TEKT2 21836163 pred P P P P P P P P P P P P G P P P P P P GP SPAG16 ODF3 21836163 pred P G GP P GP G GP P P P P P G P G P P GP G PLEKHG5 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPAG16 PACRG 21836163 pred G G G G G G G G G G G G G FDFT1 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G NPHP4 SPAG16 21836163 pred GP G G G G GP G P G G GP G GP G G G GP G G G G GP G G G G G SPAG16 DNAAF1 21836163 pred P GP G P GP P P G P GP GP P P GP P P G GP P P P P P P GP NFYA SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPAG16 RSPH6A 21836163 pred G P G G GP G P GP P GP G P GP GP GP G GP P GP GP GP GP GP G SPAG16 KIF3A 21836163 pred G GP G G GP GP G G GP G G G G G G G GP G GP G G G GP G G G GP GP G SPAG16 LGALS13 21836163 pred G G G G G IQCB1 SPAG16 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G AKAP14 SPAG16 21836163 pred P P P P P P P P GP UAP1 SPAG16 21836163 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G G GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8N0X2 Q5NFV6 two hybrid pooling approach 20711500 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality ADCY6 SPAG16 27173435 0676 HT SPAG16 TCHP 27173435 0676 HT SPAG16 SETD5 27173435 0676 HT ADCY6 SPAG16 27173435 0676 HT SPAG16 TCHP 27173435 0676 HT SPAG16 SETD5 27173435 0676 HT SPAG6 SPAG16 12391165 0018 LC MEIG1 SPAG16 15328412 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8N0X2 Q5NFV6 SPAG16 RPOH 0.126 20711500 Q8N0X2 O43306 SPAG16 ADCY6 0.236 27173435,unassigned1312 Q8N0X2 O95817 SPAG16 BAG3 0.126 23824909 Q9BT92 Q8N0X2 TCHP SPAG16 0.236 27173435,unassigned1312 Q9C0A6 Q8N0X2 SETD5 SPAG16 0.236 27173435,unassigned1312

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 ADCY6 SPAG16 MI:0045 experimental interaction detection MI:0461 interaction database SPAG6 SPAG16 MI:0362 inference MI:0461 interaction database BAG3 SPAG16 MI:0045 experimental interaction detection MI:0461 interaction database MEIG1 SPAG16 MI:0362 inference MI:0461 interaction database SPAG16 TCHP MI:0045 experimental interaction detection MI:0461 interaction database SPAG16 SETD5 MI:0045 experimental interaction detection MI:0461 interaction database SPAG16 STK36 MI:0362 inference MI:0461 interaction database