Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 10 105128134 105128134 + Missense_Mutation SNP T T G TCGA-OR-A5J2-01A-11D-A29I-10 TCGA-OR-A5J2-10A-01D-A29L-10 g.chr10:105128134T>G c.388T>G c.(388-390)Tcc>Gcc p.S130A ACC 10 105128134 105128134 + Missense_Mutation SNP T T G TCGA-OR-A5JY-01A-31D-A29I-10 TCGA-OR-A5JY-10A-01D-A29L-10 g.chr10:105128134T>G c.388T>G c.(388-390)Tcc>Gcc p.S130A ACC 10 105128134 105128134 + Missense_Mutation SNP T T G TCGA-OR-A5K8-01A-11D-A29I-10 TCGA-OR-A5K8-10A-01D-A29L-10 g.chr10:105128134T>G c.388T>G c.(388-390)Tcc>Gcc p.S130A ACC 10 105128134 105128134 + Missense_Mutation SNP T T G TCGA-OR-A5LR-01A-11D-A29I-10 TCGA-OR-A5LR-10A-01D-A29L-10 g.chr10:105128134T>G c.388T>G c.(388-390)Tcc>Gcc p.S130A BLCA 10 105128017 105128017 + Missense_Mutation SNP C C T TCGA-FD-A43X-01A-11D-A23U-08 TCGA-FD-A43X-10A-01D-A23U-08 g.chr10:105128017C>T c.271C>T c.(271-273)Ccg>Tcg p.P91S BLCA 10 105128037 105128037 + Silent SNP A A G TCGA-DK-A1AA-01A-11D-A13W-08 TCGA-DK-A1AA-10A-01D-A13W-08 g.chr10:105128037A>G c.291A>G c.(289-291)ctA>ctG p.L97L BLCA 10 105128238 105128238 + Silent SNP G G T TCGA-DK-A3IK-01A-32D-A21A-08 TCGA-DK-A3IK-10A-01D-A21A-08 g.chr10:105128238G>T c.492G>T c.(490-492)ccG>ccT p.P164P BLCA 10 105128280 105128280 + Silent SNP C C A TCGA-FD-A5BR-01A-11D-A26M-08 TCGA-FD-A5BR-10A-01D-A26K-08 g.chr10:105128280C>A c.534C>A c.(532-534)gcC>gcA p.A178A BLCA 10 105133276 105133277 + Frame_Shift_Ins INS - - A TCGA-C4-A0F7-01A-11D-A10S-08 TCGA-C4-A0F7-10A-01D-A10S-08 g.chr10:105133276_105133277insA c.721_722insA c.(721-723)tatfs p.Y241fs BLCA 10 105139367 105139368 + Frame_Shift_Ins INS - - T TCGA-ZF-AA4W-01A-12D-A38G-08 TCGA-ZF-AA4W-10A-01D-A38J-08 g.chr10:105139367_105139368insT c.1116_1117insT c.(1117-1119)tttfs p.F373fs BLCA 10 105141541 105141541 + Missense_Mutation SNP A A G TCGA-E7-A5KE-01A-11D-A289-08 TCGA-E7-A5KE-10A-01D-A289-08 g.chr10:105141541A>G c.1477A>G c.(1477-1479)Act>Gct p.T493A BRCA 10 105139467 105139467 + Frame_Shift_Del DEL A A - TCGA-A8-A09Z-01A-11W-A019-09 TCGA-A8-A09Z-10A-01W-A021-09 g.chr10:105139467delA c.1216delA c.(1216-1218)aaafs p.K407fs BRCA 10 105141539 105141539 + Missense_Mutation SNP C C T TCGA-GM-A2D9-01A-11D-A18P-09 TCGA-GM-A2D9-11A-42D-A18P-09 g.chr10:105141539C>T c.1475C>T c.(1474-1476)tCa>tTa p.S492L BRCA 10 105145226 105145226 + Missense_Mutation SNP G G A TCGA-C8-A1HK-01A-21D-A13L-09 TCGA-C8-A1HK-10A-01D-A13O-09 g.chr10:105145226G>A c.1808G>A c.(1807-1809)gGg>gAg p.G603E BRCA 10 105147961 105147961 + Missense_Mutation SNP G G C TCGA-AC-A5XS-01A-11D-A29N-09 TCGA-AC-A5XS-11A-13D-A29N-09 g.chr10:105147961G>C c.2384G>C c.(2383-2385)gGa>gCa p.G795A CESC 10 105139503 105139503 + Missense_Mutation SNP G G T TCGA-JX-A3Q0-01A-11D-A21Q-09 TCGA-JX-A3Q0-10A-01D-A21Q-09 g.chr10:105139503G>T c.1252G>T c.(1252-1254)Gat>Tat p.D418Y CESC 10 105141483 105141483 + Silent SNP C C T TCGA-EK-A2PG-01A-11D-A18J-09 TCGA-EK-A2PG-10A-01D-A18J-09 g.chr10:105141483C>T c.1419C>T c.(1417-1419)ctC>ctT p.L473L CESC 10 105141587 105141587 + Missense_Mutation SNP A A T TCGA-FU-A3HZ-01A-11D-A20U-09 TCGA-FU-A3HZ-10A-01D-A20U-09 g.chr10:105141587A>T c.1523A>T c.(1522-1524)aAa>aTa p.K508I COAD 10 105133189 105133189 + Missense_Mutation SNP A A G TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr10:105133189A>G c.634A>G c.(634-636)Aca>Gca p.T212A COAD 10 105138128 105138128 + Missense_Mutation SNP G G C TCGA-CM-5341-01A-01D-1408-10 TCGA-CM-5341-10A-01D-1408-10 g.chr10:105138128G>C c.934G>C c.(934-936)Gac>Cac p.D312H COAD 10 105138145 105138145 + Silent SNP G G A TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr10:105138145G>A c.951G>A c.(949-951)ttG>ttA p.L317L COAD 10 105139368 105139368 + Frame_Shift_Del DEL T T - TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr10:105139368delT c.1117delT c.(1117-1119)tttfs p.F374fs COAD 10 105139437 105139437 + Nonsense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:105139437G>T c.1186G>T c.(1186-1188)Gaa>Taa p.E396* COAD 10 105139509 105139509 + Missense_Mutation SNP A A G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:105139509A>G c.1258A>G c.(1258-1260)Aat>Gat p.N420D COAD 10 105139519 105139519 + Missense_Mutation SNP C C A TCGA-CK-5913-01A-11D-1650-10 TCGA-CK-5913-10A-01D-1650-10 g.chr10:105139519C>A c.1268C>A c.(1267-1269)cCt>cAt p.P423H COAD 10 105139718 105139718 + Missense_Mutation SNP G G A TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr10:105139718G>A c.1355G>A c.(1354-1356)cGc>cAc p.R452H COAD 10 105141557 105141557 + Missense_Mutation SNP C C T TCGA-A6-6141-01A-11D-1771-10 TCGA-A6-6141-10A-01D-1771-10 g.chr10:105141557C>T c.1493C>T c.(1492-1494)tCg>tTg p.S498L COAD 10 105147060 105147060 + Missense_Mutation SNP T T G TCGA-AA-A00E-01A-01W-A005-10 TCGA-AA-A00E-10A-01W-A005-10 g.chr10:105147060T>G c.1958T>G c.(1957-1959)cTc>cGc p.L653R COAD 10 105147825 105147825 + Missense_Mutation SNP G G A TCGA-CM-4752-01A-01D-1408-10 TCGA-CM-4752-10A-01D-1408-10 g.chr10:105147825G>A c.2248G>A c.(2248-2250)Gat>Aat p.D750N COAD 10 105147866 105147866 + Missense_Mutation SNP G G T TCGA-D5-6898-01A-11D-1924-10 TCGA-D5-6898-10A-01D-1924-10 g.chr10:105147866G>T c.2289G>T c.(2287-2289)gaG>gaT p.E763D COADREAD 10 105133189 105133189 + Missense_Mutation SNP A A G TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr10:105133189A>G c.634A>G c.(634-636)Aca>Gca p.T212A COADREAD 10 105138095 105138095 + Nonsense_Mutation SNP C C T TCGA-AF-2693-01A-02D-1733-10 TCGA-AF-2693-10A-01D-1733-10 g.chr10:105138095C>T c.901C>T c.(901-903)Cga>Tga p.R301* COADREAD 10 105138128 105138128 + Missense_Mutation SNP G G C TCGA-CM-5341-01A-01D-1408-10 TCGA-CM-5341-10A-01D-1408-10 g.chr10:105138128G>C c.934G>C c.(934-936)Gac>Cac p.D312H COADREAD 10 105138145 105138145 + Silent SNP G G A TCGA-AA-3715-01A-01W-0900-09 TCGA-AA-3715-10A-01W-0900-09 g.chr10:105138145G>A c.951G>A c.(949-951)ttG>ttA p.L317L COADREAD 10 105139368 105139368 + Frame_Shift_Del DEL T T - TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr10:105139368delT c.1117delT c.(1117-1119)tttfs p.F374fs COADREAD 10 105139437 105139437 + Nonsense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:105139437G>T c.1186G>T c.(1186-1188)Gaa>Taa p.E396* COADREAD 10 105139509 105139509 + Missense_Mutation SNP A A G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr10:105139509A>G c.1258A>G c.(1258-1260)Aat>Gat p.N420D COADREAD 10 105139519 105139519 + Missense_Mutation SNP C C A TCGA-CK-5913-01A-11D-1650-10 TCGA-CK-5913-10A-01D-1650-10 g.chr10:105139519C>A c.1268C>A c.(1267-1269)cCt>cAt p.P423H COADREAD 10 105139718 105139718 + Missense_Mutation SNP G G A TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr10:105139718G>A c.1355G>A c.(1354-1356)cGc>cAc p.R452H COADREAD 10 105141557 105141557 + Missense_Mutation SNP C C T TCGA-A6-6141-01A-11D-1771-10 TCGA-A6-6141-10A-01D-1771-10 g.chr10:105141557C>T c.1493C>T c.(1492-1494)tCg>tTg p.S498L COADREAD 10 105147060 105147060 + Missense_Mutation SNP T T G TCGA-AA-A00E-01A-01W-A005-10 TCGA-AA-A00E-10A-01W-A005-10 g.chr10:105147060T>G c.1958T>G c.(1957-1959)cTc>cGc p.L653R COADREAD 10 105147386 105147386 + Nonsense_Mutation SNP G G T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr10:105147386G>T c.2116G>T c.(2116-2118)Gaa>Taa p.E706* COADREAD 10 105147825 105147825 + Missense_Mutation SNP G G A TCGA-CM-4752-01A-01D-1408-10 TCGA-CM-4752-10A-01D-1408-10 g.chr10:105147825G>A c.2248G>A c.(2248-2250)Gat>Aat p.D750N COADREAD 10 105147866 105147866 + Missense_Mutation SNP G G T TCGA-D5-6898-01A-11D-1924-10 TCGA-D5-6898-10A-01D-1924-10 g.chr10:105147866G>T c.2289G>T c.(2287-2289)gaG>gaT p.E763D ESCA 10 105127805 105127805 + Missense_Mutation SNP C C A TCGA-LN-A4A9-01A-11D-A28B-09 TCGA-LN-A4A9-10A-01D-A28E-09 g.chr10:105127805C>A c.59C>A c.(58-60)cCg>cAg p.P20Q ESCA 10 105147814 105147814 + Missense_Mutation SNP A A G TCGA-LN-A49R-01A-11D-A247-09 TCGA-LN-A49R-10A-01D-A247-09 g.chr10:105147814A>G c.2237A>G c.(2236-2238)gAt>gGt p.D746G GBM 10 105145152 105145152 + Silent SNP G G A TCGA-32-4213-01A-01D-1353-08 TCGA-32-4213-10A-01D-1353-08 g.chr10:105145152G>A c.1734G>A c.(1732-1734)ttG>ttA p.L578L GBMLGG 10 105145152 105145152 + Silent SNP G G A TCGA-32-4213-01A-01D-1353-08 TCGA-32-4213-10A-01D-1353-08 g.chr10:105145152G>A c.1734G>A c.(1732-1734)ttG>ttA p.L578L GBMLGG 10 105145230 105145230 + Silent SNP C C T TCGA-HT-7691-01A-11D-2253-08 TCGA-HT-7691-10A-01D-2253-08 g.chr10:105145230C>T c.1812C>T c.(1810-1812)ggC>ggT p.G604G HNSC 10 105127982 105127982 + Frame_Shift_Del DEL C C - TCGA-P3-A6T6-01A-11D-A34J-08 TCGA-P3-A6T6-10A-01D-A34M-08 g.chr10:105127982delC c.236delC c.(235-237)gccfs p.A79fs HNSC 10 105133180 105133180 + Missense_Mutation SNP G G A TCGA-CV-7415-01A-11D-2078-08 TCGA-CV-7415-10A-01D-2078-08 g.chr10:105133180G>A c.625G>A c.(625-627)Gga>Aga p.G209R HNSC 10 105133311 105133311 + Silent SNP C C T TCGA-CQ-5333-01A-01D-2394-08 TCGA-CQ-5333-10A-01D-2394-08 g.chr10:105133311C>T c.756C>T c.(754-756)gtC>gtT p.V252V HNSC 10 105139408 105139408 + Missense_Mutation SNP T T G TCGA-CV-7429-01A-11D-2129-08 TCGA-CV-7429-10A-01D-2129-08 g.chr10:105139408T>G c.1157T>G c.(1156-1158)tTg>tGg p.L386W HNSC 10 105139422 105139422 + Nonsense_Mutation SNP G G T TCGA-CR-6472-01A-11D-1870-08 TCGA-CR-6472-10A-01D-1870-08 g.chr10:105139422G>T c.1171G>T c.(1171-1173)Gaa>Taa p.E391* HNSC 10 105139526 105139526 + Missense_Mutation SNP C C G TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr10:105139526C>G c.1275C>G c.(1273-1275)aaC>aaG p.N425K HNSC 10 105143116 105143116 + Missense_Mutation SNP T T A TCGA-UF-A7JA-01A-12D-A34J-08 TCGA-UF-A7JA-10A-01D-A34M-08 g.chr10:105143116T>A c.1656T>A c.(1654-1656)agT>agA p.S552R HNSC 10 105146990 105146990 + Missense_Mutation SNP G G T TCGA-CQ-5323-01A-01D-1683-08 TCGA-CQ-5323-10A-01D-1683-08 g.chr10:105146990G>T c.1888G>T c.(1888-1890)Gtg>Ttg p.V630L KIPAN 10 105133273 105133273 + Missense_Mutation SNP T T G TCGA-BP-5182-01A-01D-1429-08 TCGA-BP-5182-11A-01D-1429-08 g.chr10:105133273T>G c.718T>G c.(718-720)Ttt>Gtt p.F240V KIPAN 10 105139365 105139365 + Splice_Site SNP G G C TCGA-B0-5399-01A-01D-1501-10 TCGA-B0-5399-10A-01D-1501-10 g.chr10:105139365G>C c.1114G>C c.(1114-1116)Gta>Cta p.V372L KIRC 10 105133273 105133273 + Missense_Mutation SNP T T G TCGA-BP-5182-01A-01D-1429-08 TCGA-BP-5182-11A-01D-1429-08 g.chr10:105133273T>G c.718T>G c.(718-720)Ttt>Gtt p.F240V KIRC 10 105139365 105139365 + Splice_Site SNP G G C TCGA-B0-5399-01A-01D-1501-10 TCGA-B0-5399-10A-01D-1501-10 g.chr10:105139365G>C c.1114G>C c.(1114-1116)Gta>Cta p.V372L LGG 10 105145230 105145230 + Silent SNP C C T TCGA-HT-7691-01A-11D-2253-08 TCGA-HT-7691-10A-01D-2253-08 g.chr10:105145230C>T c.1812C>T c.(1810-1812)ggC>ggT p.G604G LIHC 10 105139430 105139430 + Silent SNP A A G TCGA-FV-A2QR-01A-11D-A20W-10 TCGA-FV-A2QR-11A-11D-A20W-10 g.chr10:105139430A>G c.1179A>G c.(1177-1179)ggA>ggG p.G393G LUAD 10 105133135 105133135 + Missense_Mutation SNP G G C TCGA-MN-A4N4-01A-12D-A24P-08 TCGA-MN-A4N4-10A-01D-A24P-08 g.chr10:105133135G>C c.580G>C c.(580-582)Gac>Cac p.D194H LUAD 10 105133151 105133151 + Missense_Mutation SNP G G C TCGA-55-7913-01B-11D-2238-08 TCGA-55-7913-10A-01D-2238-08 g.chr10:105133151G>C c.596G>C c.(595-597)aGt>aCt p.S199T LUAD 10 105139429 105139429 + Missense_Mutation SNP G G T TCGA-55-8514-01A-11D-2393-08 TCGA-55-8514-10A-01D-2393-08 g.chr10:105139429G>T c.1178G>T c.(1177-1179)gGa>gTa p.G393V LUAD 10 105141483 105141483 + Silent SNP C C G TCGA-55-6968-01A-11D-1945-08 TCGA-55-6968-11A-01D-1945-08 g.chr10:105141483C>G c.1419C>G c.(1417-1419)ctC>ctG p.L473L LUAD 10 105143084 105143084 + Missense_Mutation SNP C C T TCGA-86-8673-01A-11D-2393-08 TCGA-86-8673-10A-01D-2393-08 g.chr10:105143084C>T c.1624C>T c.(1624-1626)Cac>Tac p.H542Y LUAD 10 105145201 105145201 + Missense_Mutation SNP C C G TCGA-95-7948-01A-11D-2184-08 TCGA-95-7948-10A-01D-2184-08 g.chr10:105145201C>G c.1783C>G c.(1783-1785)Cca>Gca p.P595A LUSC 10 105138194 105138194 + Missense_Mutation SNP C C G TCGA-22-5482-01A-01D-1632-08 TCGA-22-5482-11A-01D-1632-08 g.chr10:105138194C>G c.1000C>G c.(1000-1002)Cag>Gag p.Q334E LUSC 10 105147936 105147936 + Silent SNP C C A TCGA-85-6561-01A-11D-1817-08 TCGA-85-6561-10A-01D-1817-08 g.chr10:105147936C>A c.2359C>A c.(2359-2361)Cga>Aga p.R787R OV 10 105143003 105143003 + Missense_Mutation SNP C C G TCGA-10-0930-01A-02W-0421-09 TCGA-10-0930-11A-01W-0977-09 g.chr10:105143003C>G c.1543C>G c.(1543-1545)Ctt>Gtt p.L515V OV 10 105147827 105147827 + Silent SNP T T C TCGA-24-2281-01A-01W-0799-08 TCGA-24-2281-10A-01W-0799-08 g.chr10:105147827T>C c.2250T>C c.(2248-2250)gaT>gaC p.D750D PAAD 10 105128042 105128042 + Missense_Mutation SNP C C A TCGA-FZ-5924-01A-13D-1609-08 TCGA-FZ-5924-11A-01D-1609-08 g.chr10:105128042C>A c.296C>A c.(295-297)gCc>gAc p.A99D PRAD 10 105133312 105133312 + Missense_Mutation SNP T T A TCGA-HC-7211-01A-11D-2114-08 TCGA-HC-7211-11A-01D-2114-08 g.chr10:105133312T>A c.757T>A c.(757-759)Tac>Aac p.Y253N READ 10 105138095 105138095 + Nonsense_Mutation SNP C C T TCGA-AF-2693-01A-02D-1733-10 TCGA-AF-2693-10A-01D-1733-10 g.chr10:105138095C>T c.901C>T c.(901-903)Cga>Tga p.R301* READ 10 105147386 105147386 + Nonsense_Mutation SNP G G T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr10:105147386G>T c.2116G>T c.(2116-2118)Gaa>Taa p.E706*

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 10 105141480 105141480 single base substitution T G splice_region_variant BLCA-CN 10 105145128 105145128 single base substitution G C intron_variant BLCA-CN 10 105145128 105145128 single base substitution G C missense_variant W570C 1710G>C BLCA-US 10 105128037 105128037 single base substitution A G synonymous_variant L97L 291A>G BLCA-US 10 105133276 105133276 insertion of <=200bp - A frameshift_variant Y241I? BRCA-EU 10 105123835 105123835 single base substitution C G upstream_gene_variant BRCA-EU 10 105124800 105124800 single base substitution G C upstream_gene_variant BRCA-EU 10 105126651 105126651 single base substitution G A upstream_gene_variant BRCA-EU 10 105131434 105131434 single base substitution A C intron_variant BRCA-EU 10 105131601 105131601 single base substitution G T intron_variant BRCA-EU 10 105135615 105135615 single base substitution G A intron_variant BRCA-EU 10 105135759 105135759 single base substitution G A intron_variant BRCA-EU 10 105136559 105136559 single base substitution G C intron_variant BRCA-EU 10 105136709 105136709 single base substitution G A intron_variant BRCA-EU 10 105138411 105138411 deletion of <=200bp T - intron_variant BRCA-EU 10 105139108 105139108 single base substitution G C intron_variant BRCA-EU 10 105140830 105140830 single base substitution T C intron_variant BRCA-EU 10 105142931 105142931 single base substitution A C intron_variant BRCA-EU 10 105142949 105142949 single base substitution T G intron_variant BRCA-EU 10 105142971 105142971 single base substitution A G intron_variant BRCA-EU 10 105145862 105145862 single base substitution C T intron_variant BRCA-EU 10 105149044 105149044 single base substitution G C downstream_gene_variant BRCA-EU 10 105149271 105149271 single base substitution G C downstream_gene_variant BRCA-EU 10 105150159 105150159 single base substitution G A downstream_gene_variant BRCA-EU 10 105153219 105153219 single base substitution C A downstream_gene_variant BRCA-FR 10 105124016 105124016 single base substitution G A upstream_gene_variant BRCA-FR 10 105135615 105135615 single base substitution G A intron_variant BRCA-FR 10 105135759 105135759 single base substitution G A intron_variant BRCA-FR 10 105136709 105136709 single base substitution G A intron_variant BRCA-FR 10 105150159 105150159 single base substitution G A downstream_gene_variant BRCA-UK 10 105138483 105138483 single base substitution C G intron_variant BRCA-UK 10 105153219 105153219 single base substitution C A downstream_gene_variant BRCA-US 10 105139467 105139467 deletion of <=200bp A - frameshift_variant K406 BRCA-US 10 105141539 105141539 single base substitution C T missense_variant S492L 1475C>T BRCA-US 10 105145226 105145226 single base substitution G A intron_variant BRCA-US 10 105145226 105145226 single base substitution G A missense_variant G603E 1808G>A BRCA-US 10 105147961 105147961 single base substitution G C missense_variant G740A 2219G>C BRCA-US 10 105147961 105147961 single base substitution G C missense_variant G795A 2384G>C BTCA-JP 10 105133182 105133191 deletion of <=200bp AGATCCCACA - frameshift_variant GDPT209 BTCA-JP 10 105145048 105145048 single base substitution C G intron_variant BTCA-JP 10 105147692 105147692 single base substitution G C intron_variant CESC-US 10 105139503 105139503 single base substitution G T missense_variant D418Y 1252G>T CESC-US 10 105141483 105141483 single base substitution C T synonymous_variant L473L 1419C>T CESC-US 10 105141587 105141587 single base substitution A T missense_variant K508I 1523A>T CLLE-ES 10 105136250 105136250 single base substitution G A intron_variant CLLE-ES 10 105139985 105139985 single base substitution A T intron_variant COAD-US 10 105138128 105138128 single base substitution G C missense_variant D312H 934G>C COAD-US 10 105139437 105139437 single base substitution G T stop_gained E396* 1186G>T COAD-US 10 105139509 105139509 single base substitution A G missense_variant N420D 1258A>G COAD-US 10 105139519 105139519 single base substitution C A missense_variant P423H 1268C>A COAD-US 10 105141557 105141557 single base substitution C T missense_variant S498L 1493C>T COAD-US 10 105147866 105147866 single base substitution G T missense_variant E708D 2124G>T COAD-US 10 105147866 105147866 single base substitution G T missense_variant E763D 2289G>T COAD-US 10 105151974 105151974 deletion of <=200bp T - downstream_gene_variant COAD-US 10 105152191 105152191 single base substitution C T downstream_gene_variant COCA-CN 10 105124741 105124741 single base substitution T C upstream_gene_variant COCA-CN 10 105129945 105129945 single base substitution C T intron_variant COCA-CN 10 105133297 105133297 single base substitution T C missense_variant Y248H 742T>C COCA-CN 10 105133382 105133382 single base substitution C T intron_variant COCA-CN 10 105138063 105138063 single base substitution A G missense_variant H290R 869A>G COCA-CN 10 105139343 105139343 single base substitution T G intron_variant COCA-CN 10 105140792 105140792 single base substitution C T intron_variant COCA-CN 10 105149547 105149547 single base substitution A G downstream_gene_variant COCA-CN 10 105150726 105150726 single base substitution T C downstream_gene_variant COCA-CN 10 105152126 105152126 single base substitution A C downstream_gene_variant COCA-CN 10 105153347 105153347 single base substitution A T downstream_gene_variant COCA-CN 10 105153351 105153351 single base substitution T A downstream_gene_variant EOPC-DE 10 105132578 105132578 single base substitution G A intron_variant ESAD-UK 10 105124935 105124935 deletion of <=200bp T - upstream_gene_variant ESAD-UK 10 105128891 105128891 single base substitution A C intron_variant ESAD-UK 10 105128956 105128956 single base substitution G C intron_variant ESAD-UK 10 105129550 105129550 single base substitution G C intron_variant ESAD-UK 10 105131901 105131901 single base substitution C G intron_variant ESAD-UK 10 105134614 105134614 single base substitution G A intron_variant ESAD-UK 10 105138955 105138955 single base substitution G C intron_variant ESAD-UK 10 105140953 105140953 single base substitution G A intron_variant ESAD-UK 10 105143562 105143562 single base substitution C T intron_variant ESAD-UK 10 105147479 105147479 single base substitution C T intron_variant ESAD-UK 10 105152143 105152143 single base substitution G C downstream_gene_variant GBM-US 10 105145152 105145152 single base substitution G A intron_variant GBM-US 10 105145152 105145152 single base substitution G A synonymous_variant L578L 1734G>A KIRC-US 10 105133273 105133273 single base substitution T G missense_variant F240V 718T>G KIRC-US 10 105139365 105139365 single base substitution G C missense_variant V372L 1114G>C LAML-KR 10 105134876 105134876 single base substitution C A intron_variant LGG-US 10 105145230 105145230 single base substitution C T intron_variant LGG-US 10 105145230 105145230 single base substitution C T synonymous_variant G604G 1812C>T LICA-FR 10 105123657 105123657 deletion of <=200bp T - upstream_gene_variant LICA-FR 10 105131249 105131249 single base substitution A T intron_variant LICA-FR 10 105147776 105147776 single base substitution T G missense_variant N678K 2034T>G LICA-FR 10 105147776 105147776 single base substitution T G missense_variant N733K 2199T>G LICA-FR 10 105149584 105149584 single base substitution G A downstream_gene_variant LIHC-US 10 105142994 105142994 single base substitution G C splice_acceptor_variant LINC-JP 10 105124850 105124850 single base substitution T C upstream_gene_variant LINC-JP 10 105131596 105131596 single base substitution A G intron_variant LINC-JP 10 105135771 105135771 single base substitution C T intron_variant LINC-JP 10 105139839 105139839 single base substitution A C intron_variant LIRI-JP 10 105123107 105123107 single base substitution G T upstream_gene_variant LIRI-JP 10 105129262 105129262 single base substitution C T intron_variant LIRI-JP 10 105133571 105133571 single base substitution A G intron_variant LIRI-JP 10 105136370 105136370 single base substitution A C intron_variant LIRI-JP 10 105142365 105142365 single base substitution T A intron_variant LIRI-JP 10 105142830 105142830 single base substitution T C intron_variant LIRI-JP 10 105142837 105142837 single base substitution T C intron_variant LIRI-JP 10 105142848 105142848 single base substitution T C intron_variant LIRI-JP 10 105142886 105142886 single base substitution A G intron_variant LIRI-JP 10 105144160 105144160 single base substitution G A intron_variant LIRI-JP 10 105145298 105145298 single base substitution T G intron_variant LIRI-JP 10 105146235 105146235 single base substitution T C intron_variant LIRI-JP 10 105147068 105147068 single base substitution G A missense_variant V601I 1801G>A LIRI-JP 10 105147068 105147068 single base substitution G A missense_variant V656I 1966G>A LIRI-JP 10 105147352 105147352 single base substitution T C synonymous_variant L639L 1917T>C LIRI-JP 10 105147352 105147352 single base substitution T C synonymous_variant L694L 2082T>C LIRI-JP 10 105147356 105147356 single base substitution T C missense_variant W641R 1921T>C LIRI-JP 10 105147356 105147356 single base substitution T C missense_variant W696R 2086T>C LIRI-JP 10 105148106 105148106 insertion of <=200bp - T 3_prime_UTR_variant LIRI-JP 10 105150371 105150371 single base substitution C A downstream_gene_variant LIRI-JP 10 105151125 105151125 single base substitution T C downstream_gene_variant LIRI-JP 10 105151130 105151130 single base substitution T G downstream_gene_variant LIRI-JP 10 105151358 105151358 single base substitution G T downstream_gene_variant LUSC-KR 10 105124683 105124683 single base substitution C T upstream_gene_variant LUSC-KR 10 105131601 105131601 single base substitution G A intron_variant LUSC-KR 10 105134903 105134903 single base substitution T A intron_variant LUSC-KR 10 105148650 105148650 single base substitution A C 3_prime_UTR_variant LUSC-US 10 105138194 105138194 single base substitution C G missense_variant Q334E 1000C>G LUSC-US 10 105147936 105147936 single base substitution C A synonymous_variant R732R 2194C>A LUSC-US 10 105147936 105147936 single base substitution C A synonymous_variant R787R 2359C>A MALY-DE 10 105123624 105123624 single base substitution C T upstream_gene_variant MALY-DE 10 105135364 105135364 single base substitution G C intron_variant MALY-DE 10 105139278 105139278 single base substitution T A intron_variant MALY-DE 10 105146126 105146126 single base substitution G T intron_variant MELA-AU 10 105123094 105123094 single base substitution G A upstream_gene_variant MELA-AU 10 105123239 105123239 single base substitution G A upstream_gene_variant MELA-AU 10 105123770 105123770 single base substitution G A upstream_gene_variant MELA-AU 10 105123787 105123787 single base substitution C T upstream_gene_variant MELA-AU 10 105123852 105123852 single base substitution G A upstream_gene_variant MELA-AU 10 105123997 105123997 single base substitution C T upstream_gene_variant MELA-AU 10 105124153 105124153 single base substitution C A upstream_gene_variant MELA-AU 10 105124325 105124325 single base substitution C T upstream_gene_variant MELA-AU 10 105124532 105124532 single base substitution G A upstream_gene_variant MELA-AU 10 105124655 105124655 single base substitution G A upstream_gene_variant MELA-AU 10 105124781 105124781 single base substitution C T upstream_gene_variant MELA-AU 10 105125666 105125666 single base substitution A G upstream_gene_variant MELA-AU 10 105125996 105125996 single base substitution G A upstream_gene_variant MELA-AU 10 105126160 105126160 single base substitution C T upstream_gene_variant MELA-AU 10 105126174 105126174 single base substitution A T upstream_gene_variant MELA-AU 10 105126785 105126785 single base substitution G A upstream_gene_variant MELA-AU 10 105127006 105127006 single base substitution G A upstream_gene_variant MELA-AU 10 105130373 105130373 single base substitution C T intron_variant MELA-AU 10 105130718 105130719 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 10 105130993 105130993 single base substitution C T intron_variant MELA-AU 10 105132332 105132332 single base substitution C T intron_variant MELA-AU 10 105133324 105133324 single base substitution G A missense_variant E257K 769G>A MELA-AU 10 105133571 105133571 single base substitution A G intron_variant MELA-AU 10 105134048 105134048 single base substitution C T intron_variant MELA-AU 10 105136180 105136180 single base substitution C T intron_variant MELA-AU 10 105136561 105136561 single base substitution G A intron_variant MELA-AU 10 105136899 105136899 single base substitution C T intron_variant MELA-AU 10 105138033 105138033 single base substitution G A missense_variant R280Q 839G>A MELA-AU 10 105138437 105138438 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 10 105138949 105138949 single base substitution A G intron_variant MELA-AU 10 105139645 105139645 single base substitution C T missense_variant P428S 1282C>T MELA-AU 10 105140902 105140902 single base substitution C T intron_variant MELA-AU 10 105142009 105142009 single base substitution C T intron_variant MELA-AU 10 105143590 105143590 single base substitution C T intron_variant MELA-AU 10 105143593 105143593 single base substitution C T intron_variant MELA-AU 10 105144500 105144500 single base substitution T C intron_variant MELA-AU 10 105146938 105146938 single base substitution G A stop_gained W557* 1671G>A MELA-AU 10 105146938 105146938 single base substitution G A stop_gained W612* 1836G>A MELA-AU 10 105148595 105148595 single base substitution G A 3_prime_UTR_variant MELA-AU 10 105148891 105148891 single base substitution G A downstream_gene_variant MELA-AU 10 105149128 105149129 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU 10 105150305 105150305 single base substitution G A downstream_gene_variant MELA-AU 10 105150503 105150503 single base substitution T C downstream_gene_variant MELA-AU 10 105151522 105151522 single base substitution C T downstream_gene_variant MELA-AU 10 105151702 105151702 single base substitution G A downstream_gene_variant MELA-AU 10 105153139 105153139 single base substitution C T downstream_gene_variant MELA-AU 10 105153324 105153324 single base substitution G A downstream_gene_variant ORCA-IN 10 105143019 105143019 single base substitution C T missense_variant S520L 1559C>T OV-AU 10 105123987 105123987 single base substitution C T upstream_gene_variant OV-AU 10 105124944 105124944 single base substitution T C upstream_gene_variant OV-AU 10 105127555 105127555 single base substitution C G upstream_gene_variant OV-AU 10 105127681 105127681 single base substitution C T upstream_gene_variant OV-AU 10 105127715 105127715 single base substitution C A upstream_gene_variant OV-AU 10 105127716 105127716 single base substitution G A upstream_gene_variant OV-AU 10 105129049 105129049 single base substitution C A intron_variant OV-AU 10 105135311 105135311 single base substitution G C intron_variant OV-AU 10 105137047 105137047 single base substitution G A intron_variant OV-AU 10 105137259 105137259 single base substitution T C intron_variant OV-AU 10 105146070 105146070 single base substitution C T intron_variant OV-AU 10 105149137 105149137 single base substitution T C downstream_gene_variant OV-US 10 105143003 105143003 single base substitution C G missense_variant L515V 1543C>G PACA-AU 10 105129036 105129036 single base substitution G A intron_variant PACA-AU 10 105131016 105131016 single base substitution A G intron_variant PACA-AU 10 105137413 105137413 single base substitution G C intron_variant PACA-AU 10 105142178 105142178 single base substitution C T intron_variant PACA-AU 10 105153347 105153347 single base substitution A T downstream_gene_variant PACA-CA 10 105125739 105125739 single base substitution C A upstream_gene_variant PACA-CA 10 105133138 105133138 single base substitution C T stop_gained Q195* 583C>T PACA-CA 10 105138076 105138076 single base substitution T C synonymous_variant N294N 882T>C PACA-CA 10 105139711 105139711 single base substitution C T stop_gained R450* 1348C>T PACA-CA 10 105141907 105141907 single base substitution T C intron_variant PACA-CA 10 105144681 105144681 single base substitution A T intron_variant PACA-CA 10 105144696 105144696 deletion of <=200bp G - intron_variant PACA-CA 10 105145208 105145208 single base substitution G T intron_variant PACA-CA 10 105145208 105145208 single base substitution G T missense_variant G597V 1790G>T PACA-CA 10 105148506 105148506 single base substitution T A 3_prime_UTR_variant PACA-CA 10 105148767 105148767 deletion of <=200bp T - 3_prime_UTR_variant PACA-CA 10 105148946 105148946 deletion of <=200bp A - downstream_gene_variant PACA-CA 10 105149925 105149925 single base substitution G A downstream_gene_variant PACA-CA 10 105153134 105153134 single base substitution G A downstream_gene_variant PACA-CA 10 105153508 105153508 single base substitution G A downstream_gene_variant PAEN-IT 10 105139926 105139926 single base substitution G A intron_variant PAEN-IT 10 105144834 105144834 single base substitution T C intron_variant PBCA-DE 10 105123975 105123975 single base substitution C T upstream_gene_variant PBCA-DE 10 105131988 105131988 single base substitution G T intron_variant PBCA-DE 10 105133394 105133395 deletion of <=200bp GT - intron_variant PBCA-DE 10 105138115 105138115 single base substitution G A synonymous_variant L307L 921G>A PBCA-DE 10 105143299 105143299 single base substitution G A intron_variant PBCA-DE 10 105144937 105144937 single base substitution G T intron_variant PRAD-CA 10 105124867 105124867 single base substitution G A upstream_gene_variant PRAD-UK 10 105132037 105132037 single base substitution G T intron_variant PRAD-UK 10 105138371 105138371 single base substitution C T intron_variant PRAD-US 10 105133312 105133312 single base substitution T A missense_variant Y253N 757T>A READ-US 10 105138095 105138095 single base substitution C T stop_gained R301* 901C>T RECA-EU 10 105127592 105127592 single base substitution G C upstream_gene_variant RECA-EU 10 105127617 105127617 single base substitution T C upstream_gene_variant RECA-EU 10 105140000 105140000 single base substitution C G intron_variant RECA-EU 10 105140467 105140467 single base substitution G A intron_variant RECA-EU 10 105151888 105151888 single base substitution A T downstream_gene_variant SKCA-BR 10 105126469 105126469 single base substitution A G upstream_gene_variant SKCA-BR 10 105128979 105128979 single base substitution A C intron_variant SKCA-BR 10 105132110 105132110 single base substitution G T intron_variant SKCA-BR 10 105134876 105134876 insertion of <=200bp - CA intron_variant SKCA-BR 10 105143357 105143359 deletion of <=200bp CAG - intron_variant SKCA-BR 10 105144288 105144288 single base substitution C T intron_variant SKCA-BR 10 105145657 105145657 single base substitution A G intron_variant SKCA-BR 10 105146421 105146421 insertion of <=200bp - AT intron_variant SKCA-BR 10 105146692 105146692 single base substitution G T intron_variant SKCA-BR 10 105149429 105149429 single base substitution C T downstream_gene_variant SKCA-BR 10 105152206 105152206 single base substitution A C downstream_gene_variant SKCA-BR 10 105153542 105153542 single base substitution G A downstream_gene_variant SKCM-US 10 105147410 105147410 single base substitution G A missense_variant V659I 1975G>A SKCM-US 10 105147410 105147410 single base substitution G A missense_variant V714I 2140G>A STAD-US 10 105138238 105138238 single base substitution T C synonymous_variant S348S 1044T>C STAD-US 10 105145090 105145090 single base substitution C A intron_variant STAD-US 10 105145090 105145090 single base substitution C A missense_variant L558M 1672C>A STAD-US 10 105146935 105146935 single base substitution C G synonymous_variant L556L 1668C>G STAD-US 10 105146935 105146935 single base substitution C G synonymous_variant L611L 1833C>G STAD-US 10 105147784 105147784 single base substitution G A missense_variant R681Q 2042G>A STAD-US 10 105147784 105147784 single base substitution G A missense_variant R736Q 2207G>A STAD-US 10 105151956 105151956 single base substitution T C downstream_gene_variant THCA-SA 10 105152156 105152156 single base substitution T C downstream_gene_variant UCEC-US 10 105138096 105138096 single base substitution G A missense_variant R301Q 902G>A UCEC-US 10 105138180 105138180 single base substitution T C missense_variant I329T 986T>C UCEC-US 10 105139711 105139711 single base substitution C T stop_gained R450* 1348C>T UCEC-US 10 105141577 105141577 single base substitution C T missense_variant R505C 1513C>T UCEC-US 10 105143015 105143015 single base substitution G T stop_gained E519* 1555G>T UCEC-US 10 105145247 105145247 single base substitution G A intron_variant UCEC-US 10 105145247 105145247 single base substitution G A missense_variant R610Q 1829G>A UCEC-US 10 105147829 105147829 single base substitution A C missense_variant D696A 2087A>C UCEC-US 10 105147829 105147829 single base substitution A C missense_variant D751A 2252A>C UCEC-US 10 105147964 105147964 single base substitution C A missense_variant A741D 2222C>A UCEC-US 10 105147964 105147964 single base substitution C A missense_variant A796D 2387C>A UCEC-US 10 105152017 105152017 single base substitution G A downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand B104-0 COSM1745603 c.1710G>C p.W570C Substitution - Missense 10:103385371-103385371 + B55-Tumor COSM3930904 c.1416T>G p.G472G Substitution - coding silent 10:103381723-103381723 + TCGA-A6-6141-01 COSM1345557 c.1493C>T p.S498L Substitution - Missense 10:103381800-103381800 + TCGA-D1-A17Q-01 COSM914324 c.902G>A p.R301Q Substitution - Missense 10:103378339-103378339 + TCGA-DK-A1AA-01 COSM1296895 c.291A>G p.L97L Substitution - coding silent 10:103368280-103368280 + LUAD-5V8LT COSM401106 c.2039A>G p.N680S Substitution - Missense 10:103387552-103387552 + SA030 COSM212952 c.1204A>G p.K402E Substitution - Missense 10:103379698-103379698 + CAL33 COSM2059787 c.2009G>A p.G670E Substitution - Missense 10:103387522-103387522 + PTC-10C COSM4144318 c.388T>G p.S130A Substitution - Missense 10:103368377-103368377 + CLL121 COSM1289305 c.352C>A p.R118S Substitution - Missense 10:103368341-103368341 + BK0028 COSM4186708 c.2193G>A p.M731I Substitution - Missense 10:103388013-103388013 + sysucc-834T COSM5485358 c.869A>G p.H290R Substitution - Missense 10:103378306-103378306 + TCGA-CA-6717-01 COSM1345555 c.1258A>G p.N420D Substitution - Missense 10:103379752-103379752 + T613 COSM4732022 c.2072G>A p.G691D Substitution - Missense 10:103387585-103387585 + CHC1763T COSM4789692 c.2199T>G p.N733K Substitution - Missense 10:103388019-103388019 + TCGA-HU-A4H3-01 COSM4011357 c.1044T>C p.S348S Substitution - coding silent 10:103378481-103378481 + TCGA-AC-A5XS-01 COSM4390712 c.2384G>C p.G795A Substitution - Missense 10:103388204-103388204 + CHC1763T COSM4789692 c.2199T>G p.N733K Substitution - Missense 10:103388019-103388019 + PTC-53C COSM4144318 c.388T>G p.S130A Substitution - Missense 10:103368377-103368377 + TCGA-32-4213-01 COSM3396894 c.1734G>A p.L578L Substitution - coding silent 10:103385395-103385395 + TCGA-B0-5399-01 COSM465214 c.1114G>C p.V372L Substitution - Missense 10:103379608-103379608 + TCGA-10-0930-01 COSM76669 c.1543C>G p.L515V Substitution - Missense 10:103383246-103383246 + sysucc-311T COSM5477075 c.742T>C p.Y248H Substitution - Missense 10:103373540-103373540 + TCGA-D5-6898-01 COSM1345559 c.2289G>T p.E763D Substitution - Missense 10:103388109-103388109 + ESCC_118 COSM5640141 c.2027C>T p.T676I Substitution - Missense 10:103387540-103387540 + 587284 COSM914327 c.1513C>T p.R505C Substitution - Missense 10:103381820-103381820 + TCGA-GM-A2D9-01 COSM3806372 c.1475C>T p.S492L Substitution - Missense 10:103381782-103381782 + OSCC-GB_00980111 COSM4882107 c.1559C>T p.S520L Substitution - Missense 10:103383262-103383262 + KM12 COSM1675528 c.2000G>A p.G667E Substitution - Missense 10:103387345-103387345 + SK-OV-3 COSM347776 c.2260A>G p.T754A Substitution - Missense 10:103388080-103388080 + PCSI_0226_Pa_P_526 COSM914326 c.1348C>T p.R450* Substitution - Nonsense 10:103379954-103379954 + TCGA-85-6561-01 COSM683487 c.2359C>A p.R787R Substitution - coding silent 10:103388179-103388179 + TCGA-AP-A051-01 COSM914330 c.2252A>C p.D751A Substitution - Missense 10:103388072-103388072 + TCGA-BS-A0UF-01 COSM914328 c.1555G>T p.E519* Substitution - Nonsense 10:103383258-103383258 + TCGA-HT-7691-01 COSM3966855 c.1812C>T p.G604G Substitution - coding silent 10:103385473-103385473 + SJMB002 COSM255884 c.1210_1212delAAG p.K404delK Deletion - In frame 10:103379704-103379706 + RK119_C01 COSM3741475 c.1966G>A p.V656I Substitution - Missense 10:103387311-103387311 + TCGA-JX-A3Q0-01 COSM4824034 c.1252G>T p.D418Y Substitution - Missense 10:103379746-103379746 + ESO-0292 COSM1241808 c.432C>T p.T144T Substitution - coding silent 10:103368421-103368421 + TCGA-A8-A09Z-01 COSM5202345 c.1216delA p.D408fs*25 Deletion - Frameshift 10:103379710-103379710 + TCGA-22-5482-01 COSM683489 c.1000C>G p.Q334E Substitution - Missense 10:103378437-103378437 + 587256 COSM914329 c.1829G>A p.R610Q Substitution - Missense 10:103385490-103385490 + STC263 COSM5049857 c.1224T>C p.D408D Substitution - coding silent 10:103379718-103379718 + PCSI_0111_Pa_P_526 COSM4808278 c.583C>T p.Q195* Substitution - Nonsense 10:103373381-103373381 + UM-SCC-11B COSM4598001 c.1514G>A p.R505H Substitution - Missense 10:103381821-103381821 + B104-0-Tumor COSM1745603 c.1710G>C p.W570C Substitution - Missense 10:103385371-103385371 + YULAPE COSM1702966 c.632C>T p.P211L Substitution - Missense 10:103373430-103373430 + CLL068 COSM1289306 c.660A>G p.G220G Substitution - coding silent 10:103373458-103373458 + TCGA-CA-6717-01 COSM1345554 c.1186G>T p.E396* Substitution - Nonsense 10:103379680-103379680 + TCGA-CG-4438-01 COSM4011358 c.1672C>A p.L558M Substitution - Missense 10:103385333-103385333 + TCGA-DD-A3A2-01 COSM4928906 c.1535-1G>C p.? Unknown 10:103383237-103383237 + TCGA-B5-A11H-01 COSM914326 c.1348C>T p.R450* Substitution - Nonsense 10:103379954-103379954 + Pat_04_A COSM5836178 c.2035C>T p.P679S Substitution - Missense 10:103387548-103387548 + TCGA-AP-A051-01 COSM914331 c.2387C>A p.A796D Substitution - Missense 10:103388207-103388207 + TCGA-24-2281-01 COSM80607 c.2250T>C p.D750D Substitution - coding silent 10:103388070-103388070 + TCGA-AP-A059-01 COSM914329 c.1829G>A p.R610Q Substitution - Missense 10:103385490-103385490 + TCGA-FU-A3HZ-01 COSM4840685 c.1523A>T p.K508I Substitution - Missense 10:103381830-103381830 + TCGA-CM-5341-01 COSM1345553 c.934G>C p.D312H Substitution - Missense 10:103378371-103378371 + TCGA-BR-4184-01 COSM4011360 c.2207G>A p.R736Q Substitution - Missense 10:103388027-103388027 + PCSI_0050_Pa_X COSM3375354 c.1790G>T p.G597V Substitution - Missense 10:103385451-103385451 + KM12 COSM1675528 c.2000G>A p.G667E Substitution - Missense 10:103387345-103387345 + TCGA-EB-A553-01 COSM3433843 c.2140G>A p.V714I Substitution - Missense 10:103387653-103387653 + Pat_59_B COSM5836177 c.1984G>T p.V662L Substitution - Missense 10:103387329-103387329 + T2269 COSM4732021 c.1396T>C p.F466L Substitution - Missense 10:103380002-103380002 + TCGA-EK-A2PG-01 COSM4819784 c.1419C>T p.L473L Substitution - coding silent 10:103381726-103381726 + TCGA-CK-5913-01 COSM1345556 c.1268C>A p.P423H Substitution - Missense 10:103379762-103379762 + D28 COSM5545927 c.929C>T p.S310F Substitution - Missense 10:103378366-103378366 + TCGA-BP-5182-01 COSM465213 c.718T>G p.F240V Substitution - Missense 10:103373516-103373516 + TCGA-AP-A054-01 COSM914325 c.986T>C p.I329T Substitution - Missense 10:103378423-103378423 + SJMB002 COSM255884 c.1210_1212delAAG p.K404delK Deletion - In frame 10:103379704-103379706 + 451 COSM1742539 c.1883C>G p.A628G Substitution - Missense 10:103387228-103387228 + TCGA-BS-A0UV-01 COSM914327 c.1513C>T p.R505C Substitution - Missense 10:103381820-103381820 + TCGA-HC-7211-01 COSM1470310 c.757T>A p.Y253N Substitution - Missense 10:103373555-103373555 + TCGA-AF-2693-01 COSM1560992 c.901C>T p.R301* Substitution - Nonsense 10:103378338-103378338 + ESO-165 COSM1267377 c.420C>A p.G140G Substitution - coding silent 10:103368409-103368409 + STC246 COSM5049858 c.1860_1862delAAG p.R621delR Deletion - In frame 10:103387205-103387207 + TCGA-AA-3715-01 COSM270287 c.951G>A p.L317L Substitution - coding silent 10:103378388-103378388 + PTC-73C COSM4144318 c.388T>G p.S130A Substitution - Missense 10:103368377-103368377 + TCGA-C8-A1HK-01 COSM1474327 c.1808G>A p.G603E Substitution - Missense 10:103385469-103385469 + LUAD-VUMN6 COSM347776 c.2260A>G p.T754A Substitution - Missense 10:103388080-103388080 + PTC-70C COSM4144318 c.388T>G p.S130A Substitution - Missense 10:103368377-103368377 + TCGA-BR-4357-01 COSM4011359 c.1833C>G p.L611L Substitution - coding silent 10:103387178-103387178 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.96103 10q24-q25.2 601787

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G Missense p.K402E c.1204A>G 10 105139455 BRCA A G Synonymous p.G220G c.660A>G 10 105133215 CLL A G Synonymous p.L376L c.1128A>G 10 105139379 STAD A G Synonymous p.L97L c.291A>G 10 105128037 BLCA - A Nonsense p.Y241*fs*1 c.722dupA 10 105133277 BLCA C A Missense p.L558M c.1672C>A 10 105145090 STAD C A Missense p.R118S c.352C>A 10 105128098 CLL C A Synonymous p.G140G c.420C>A 10 105128166 ESCA C A Synonymous p.R787R c.2359C>A 10 105147936 LUSC C G Missense p.L515V c.1543C>G 10 105143003 OV C G Missense p.Q334E c.1000C>G 10 105138194 LUSC C G Synonymous p.L611L c.1833C>G 10 105146935 STAD C T Missense p.P346S c.1036C>T 10 105138230 CM C T Nonsense p.R450* c.1348C>T 10 105139711 UCEC C T Synonymous p.G604G c.1812C>T 10 105145230 LGG G A 3-UTRSNV . c.2400+730G>A 10 105148707 ALL G A Missense p.G209R c.625G>A 10 105133180 HNSC G A Missense p.G603E c.1808G>A 10 105145226 BRCA G A Missense p.G670E c.2009G>A 10 105147279 CM G A Synonymous p.L307L c.921G>A 10 105138115 MB G A Synonymous p.L578L c.1734G>A 10 105145152 GBM G C Missense p.V372L c.1114G>C 10 105139365 RCCC G T Missense p.V630L c.1888G>T 10 105146990 HNSC G T Nonsense p.E391* c.1171G>T 10 105139422 HNSC T A Missense p.Y253N c.757T>A 10 105133312 PRAD T C Missense p.I329T c.986T>C 10 105138180 UCEC T C Synonymous p.D750D c.2250T>C 10 105147827 OV T G Missense p.F240V c.718T>G 10 105133273 RCCC T G Missense p.L386W c.1157T>G 10 105139408 HNSC