PTM - CPLM Gene Name UniProt ID Type Position Code UBC P0CG48 Sumoylation 671 K UBC P0CG48 Ubiquitination 6 K UBC P0CG48 Ubiquitination 11 K UBC P0CG48 Ubiquitination 29 K UBC P0CG48 Ubiquitination 33 K UBC P0CG48 Ubiquitination 48 K UBC P0CG48 Ubiquitination 63 K UBC P0CG48 Ubiquitination 82 K UBC P0CG48 Ubiquitination 27 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UBC P0CG48 65 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P0CG48 K6-ac Acetylation __MQIFVktLTGktI P0CG48 K11-ac Acetylation FVktLTGktItLEVE P0CG48 K48-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K82-ac Acetylation GGMQIFVktLTGktI P0CG48 K87-ac Acetylation FVktLTGktItLEVE P0CG48 K124-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K158-ac Acetylation GGMQIFVktLTGktI P0CG48 K163-ac Acetylation FVktLTGktItLEVE P0CG48 K200-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K234-ac Acetylation GGMQIFVktLTGktI P0CG48 K239-ac Acetylation FVktLTGktItLEVE P0CG48 K276-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K310-ac Acetylation GGMQIFVktLTGktI P0CG48 K315-ac Acetylation FVktLTGktItLEVE P0CG48 K352-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K386-ac Acetylation GGMQIFVktLTGktI P0CG48 K391-ac Acetylation FVktLTGktItLEVE P0CG48 K428-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K462-ac Acetylation GGMQIFVktLTGktI P0CG48 K467-ac Acetylation FVktLTGktItLEVE P0CG48 K504-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K538-ac Acetylation GGMQIFVktLTGktI P0CG48 K543-ac Acetylation FVktLTGktItLEVE P0CG48 K580-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K614-ac Acetylation GGMQIFVktLTGktI P0CG48 K619-ac Acetylation FVktLTGktItLEVE P0CG48 K656-ac Acetylation QRLIFAGkQLEDGRT P0CG48 K6-m1 Methylation __MQIFVktLTGktI P0CG48 K63-m1 Methylation LsDyNIQkEstLHLV P0CG48 R72-m1 Methylation stLHLVLrLRGGMQI P0CG48 K82-m1 Methylation GGMQIFVktLTGktI P0CG48 K139-m1 Methylation LsDyNIQkEstLHLV P0CG48 R148-m1 Methylation stLHLVLrLRGGMQI P0CG48 K158-m1 Methylation GGMQIFVktLTGktI P0CG48 K215-m1 Methylation LsDyNIQkEstLHLV P0CG48 R224-m1 Methylation stLHLVLrLRGGMQI P0CG48 K234-m1 Methylation GGMQIFVktLTGktI P0CG48 K291-m1 Methylation LsDyNIQkEstLHLV P0CG48 R300-m1 Methylation stLHLVLrLRGGMQI P0CG48 K310-m1 Methylation GGMQIFVktLTGktI P0CG48 K367-m1 Methylation LsDyNIQkEstLHLV P0CG48 R376-m1 Methylation stLHLVLrLRGGMQI P0CG48 K386-m1 Methylation GGMQIFVktLTGktI P0CG48 K443-m1 Methylation LsDyNIQkEstLHLV P0CG48 R452-m1 Methylation stLHLVLrLRGGMQI P0CG48 K462-m1 Methylation GGMQIFVktLTGktI P0CG48 K519-m1 Methylation LsDyNIQkEstLHLV P0CG48 R528-m1 Methylation stLHLVLrLRGGMQI P0CG48 K538-m1 Methylation GGMQIFVktLTGktI P0CG48 K595-m1 Methylation LsDyNIQkEstLHLV P0CG48 R604-m1 Methylation stLHLVLrLRGGMQI P0CG48 K614-m1 Methylation GGMQIFVktLTGktI P0CG48 K671-m1 Methylation LsDyNIQkEstLHLV P0CG48 R680-m1 Methylation stLHLVLrLRGGV__ P0CG48 T7-p Phosphorylation _MQIFVktLTGktIt P0CG48 T12-p Phosphorylation VktLTGktItLEVEP P0CG48 T14-p Phosphorylation tLTGktItLEVEPsD P0CG48 S20-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T22-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S57-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y59-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S65-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T66-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T83-p Phosphorylation GMQIFVktLTGktIt P0CG48 T88-p Phosphorylation VktLTGktItLEVEP P0CG48 T90-p Phosphorylation tLTGktItLEVEPsD P0CG48 S96-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T98-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S133-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y135-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S141-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T142-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T159-p Phosphorylation GMQIFVktLTGktIt P0CG48 T164-p Phosphorylation VktLTGktItLEVEP P0CG48 T166-p Phosphorylation tLTGktItLEVEPsD P0CG48 S172-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T174-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S190-p Phosphorylation QDkEGIPsDQQRLIF P0CG48 S209-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y211-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S217-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T218-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T235-p Phosphorylation GMQIFVktLTGktIt P0CG48 T240-p Phosphorylation VktLTGktItLEVEP P0CG48 T242-p Phosphorylation tLTGktItLEVEPsD P0CG48 S248-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T250-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S285-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y287-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S293-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T294-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T311-p Phosphorylation GMQIFVktLTGktIt P0CG48 T316-p Phosphorylation VktLTGktItLEVEP P0CG48 T318-p Phosphorylation tLTGktItLEVEPsD P0CG48 S324-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T326-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S361-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y363-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S369-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T370-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T387-p Phosphorylation GMQIFVktLTGktIt P0CG48 T392-p Phosphorylation VktLTGktItLEVEP P0CG48 T394-p Phosphorylation tLTGktItLEVEPsD P0CG48 S400-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T402-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S437-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y439-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S445-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T446-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T463-p Phosphorylation GMQIFVktLTGktIt P0CG48 T468-p Phosphorylation VktLTGktItLEVEP P0CG48 T470-p Phosphorylation tLTGktItLEVEPsD P0CG48 S476-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T478-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S513-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y515-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S521-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T522-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T539-p Phosphorylation GMQIFVktLTGktIt P0CG48 T544-p Phosphorylation VktLTGktItLEVEP P0CG48 T546-p Phosphorylation tLTGktItLEVEPsD P0CG48 S552-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T554-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S589-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y591-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S597-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T598-p Phosphorylation yNIQkEstLHLVLrL P0CG48 T615-p Phosphorylation GMQIFVktLTGktIt P0CG48 T620-p Phosphorylation VktLTGktItLEVEP P0CG48 T622-p Phosphorylation tLTGktItLEVEPsD P0CG48 S628-p Phosphorylation ItLEVEPsDtIENVk P0CG48 T630-p Phosphorylation LEVEPsDtIENVkAk P0CG48 S665-p Phosphorylation LEDGRTLsDyNIQkE P0CG48 Y667-p Phosphorylation DGRTLsDyNIQkEst P0CG48 S673-p Phosphorylation DyNIQkEstLHLVLr P0CG48 T674-p Phosphorylation yNIQkEstLHLVLrL P0CG48 K6-sm Sumoylation __MQIFVktLTGktI P0CG48 K11-sm Sumoylation FVktLTGktItLEVE P0CG48 K27-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K48-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K63-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K82-sm Sumoylation GGMQIFVktLTGktI P0CG48 K87-sm Sumoylation FVktLTGktItLEVE P0CG48 K103-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K124-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K139-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K158-sm Sumoylation GGMQIFVktLTGktI P0CG48 K163-sm Sumoylation FVktLTGktItLEVE P0CG48 K179-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K200-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K215-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K234-sm Sumoylation GGMQIFVktLTGktI P0CG48 K239-sm Sumoylation FVktLTGktItLEVE P0CG48 K255-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K276-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K291-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K310-sm Sumoylation GGMQIFVktLTGktI P0CG48 K315-sm Sumoylation FVktLTGktItLEVE P0CG48 K331-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K352-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K367-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K386-sm Sumoylation GGMQIFVktLTGktI P0CG48 K391-sm Sumoylation FVktLTGktItLEVE P0CG48 K407-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K428-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K443-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K462-sm Sumoylation GGMQIFVktLTGktI P0CG48 K467-sm Sumoylation FVktLTGktItLEVE P0CG48 K483-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K504-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K519-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K538-sm Sumoylation GGMQIFVktLTGktI P0CG48 K543-sm Sumoylation FVktLTGktItLEVE P0CG48 K559-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K580-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K595-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K614-sm Sumoylation GGMQIFVktLTGktI P0CG48 K619-sm Sumoylation FVktLTGktItLEVE P0CG48 K635-sm Sumoylation sDtIENVkAkIQDkE P0CG48 K656-sm Sumoylation QRLIFAGkQLEDGRT P0CG48 K671-sm Sumoylation LsDyNIQkEstLHLV P0CG48 K6-ub Ubiquitination __MQIFVktLTGktI P0CG48 K11-ub Ubiquitination FVktLTGktItLEVE P0CG48 K27-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K29-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K33-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K48-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K63-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K82-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K87-ub Ubiquitination FVktLTGktItLEVE P0CG48 K103-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K105-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K109-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K124-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K139-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K158-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K163-ub Ubiquitination FVktLTGktItLEVE P0CG48 K179-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K181-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K185-ub Ubiquitination VkAkIQDkEGIPsDQ P0CG48 K200-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K215-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K234-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K239-ub Ubiquitination FVktLTGktItLEVE P0CG48 K255-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K257-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K261-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K276-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K291-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K310-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K315-ub Ubiquitination FVktLTGktItLEVE P0CG48 K331-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K333-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K337-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K352-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K367-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K386-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K391-ub Ubiquitination FVktLTGktItLEVE P0CG48 K407-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K409-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K413-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K428-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K443-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K462-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K467-ub Ubiquitination FVktLTGktItLEVE P0CG48 K483-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K485-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K489-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K504-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K519-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K538-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K543-ub Ubiquitination FVktLTGktItLEVE P0CG48 K559-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K561-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K565-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K580-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K595-ub Ubiquitination LsDyNIQkEstLHLV P0CG48 K614-ub Ubiquitination GGMQIFVktLTGktI P0CG48 K619-ub Ubiquitination FVktLTGktItLEVE P0CG48 K635-ub Ubiquitination sDtIENVkAkIQDkE P0CG48 K637-ub Ubiquitination tIENVkAkIQDkEGI P0CG48 K641-ub Ubiquitination VkAkIQDkEGIPPDQ P0CG48 K656-ub Ubiquitination QRLIFAGkQLEDGRT P0CG48 K671-ub Ubiquitination LsDyNIQkEstLHLV

PTM - dbPTM UniProt ID Position Code Type Resources References P0CG48 6 K Ubiquitylation Swiss-Prot 1010711 16443603 P0CG48 6 K Acetylation Swiss-Prot 1010711 19608861 P0CG48 11 K Ubiquitylation Swiss-Prot 1010711 16443603;16543144 P0CG48 29 K Ubiquitylation Swiss-Prot 1010711 16543144 P0CG48 48 K Ubiquitylation Swiss-Prot 1010711 16443603;16543144;17203973;17323924 P0CG48 48 K Acetylation Swiss-Prot 1010711 19608861 P0CG48 63 K Ubiquitylation Swiss-Prot 1010711 16543144;18719106 P0CG48 65 S Phosphorylation Swiss-Prot 1010711 17081983 P0CG48 76 G Isopeptide bond Swiss-Prot 1010711 -

PTM - UniProt UniProt ID Position Type PMIDs P0CG48 65 Phosphoserine; by PINK1 24660806;24751536;24784582;25527291

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type UBC IPI00179330 K 104 VKLAVLaKYYKVDE acetylation UBC IPI00179330 K 107 AVLKYYaKVDENGK acetylation UBC IPI00179330 K 113 KVDENGaKISRLRR acetylation UBC IPI00179330 K 152 LTYCFNaKPEDK__ acetylation UBC IPI00179330 K 48 RLIFAGaKQLEDGR acetylation UBC IPI00179330 K 6 _MQIFVaKTLTGKT acetylation UBC IPI00179330 S 65 YNIQKEpSTLHLVL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7316 113164 - K Ubiquitination 20639865 7316 113164 - K Ubiquitination 20972266 7316 113164 - K Ubiquitination 20622874 7316 113164 - K Sumoylation 21693764 7316 113164 - K Ubiquitination 21139048 7316 113164 - K Ubiquitination 21890473 7316 113164 - K Ubiquitination 21906983 7316 113164 - K Ubiquitination 21757738 7316 113164 - K FAT10ylation 21757738 7316 113164 - K Ubiquitination 22281738 7316 113164 - K Ubiquitination 17203973 7316 113164 - K Ubiquitination 22053931 7316 113164 - K Sumoylation 23077236 7316 113164 - K Ubiquitination 21963094 7316 113164 - K Ubiquitination 21987572 7316 113164 - K Ubiquitination 22505724 7316 113164 - K Ubiquitination 18655026 7316 113164 - K Ubiquitination 23000965 7316 113164 - K Ubiquitination 23562397 7316 113164 - K FAT10ylation 23862649 7316 113164 - K Ubiquitination 16196087 7316 113164 - K Ubiquitination 24816145 7316 113164 - K Neddylation 23105008 7316 113164 - K Ubiquitination 12938929 7316 113164 - K Ubiquitination 22542781 7316 113164 - K Ubiquitination 23101881 7316 113164 - K Ubiquitination 23823328 7316 113164 - K Sumoylation 21098080 7316 113164 - K Neddylation 18247557

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UBC Homo sapiens (Human) 48; 33; 6; 27; 11; 29; 63 "48,RLIFAGKQLEDGR; 33,KAKIQDKEGIPPD; 6,MQIFVKTLTGKT; 27,DTIENVKAKIQDK; 11,VKTLTGKTITLEV; 29,IENVKAKIQDKEG; 63,SDYNIQKESTLHL" "48:16443603,16543144,17203973,17323924; 33:21906983; 6:16443603,20972266,21906983; 27:21906983; 11:20972266,16443603,16543144,21906983; 29:16543144,21906983; 63:16543144,18719106,21906983" UBC Homo sapiens (Human) 139; 33; 48; 6; 82; 27; 11; 29; 63 "139,SGYNIQKESTLHL; 33,KAKIQDKEGIPPD; 48,RLIFAGKQLEDGR; 6,MQIFVKTLTGKT; 82,GMQIFVKTLTGKT; 27,DTIENVKAKIQDK; 11,VKTLTGKTITLEV; 29,IENVKAKIQDKEG; 63,SDYNIQKESTLHL" "139:21139048,21906983; 33:21890473,21906983; 48:21890473,21906983; 6:21890473,21906983; 82:21139048; 27:21890473,21906983; 11:21890473,21906983; 29:21890473,21906983; 63:21906983"