Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 247006160 rs5021094 G T rs5021094 7.27E-05 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 T intron GWASdb_trait 1 247010734 rs6688227 C T rs6688227 6.85E-05 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 T intron GWASdb_trait 1 247012724 rs6426183 T C rs6426183 4.60E-06 Ankle-brachial index HPOID:0003028 DOID:341 T intron GWASdb_trait 1 247018184 rs7530860 A G rs7530860 4.35E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 G intron GWASdb_trait 1 247023866 rs1630829 C T rs1630829 6.56E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 T intron GWASdb_trait 1 247048834 rs2642990 T C rs2642990 5.26E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C missense GWASdb_trait 1 247069949 rs1779969 T C rs1779969 0.00079 Erectile dysfunction after radiotherapy for prostate cancer HPOID:0000802|HPOID:0012125 DOID:1876|DOID:10283 C intron GWASdb_trait 1 247081383 rs1039010 A G rs1039010 8.42E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs7549408 1 247008439 247008439 intronic 0.926067 0.0333575914199376 GWAS of prostate cancer rs12068067 1 247025938 247025938 intronic 0.554821 0.255847109221828 GWAS of prostate cancer rs9783081 1 247016787 247016787 intronic 0.535798 0.270998911837524 GWAS of prostate cancer rs10802451 1 247027650 247027650 intronic 0.479271 0.31941884874868 GWAS of prostate cancer rs10924863 1 247046778 247046778 intronic 0.275238 0.560291606588323 GWAS of prostate cancer rs10924866 1 247084871 247084871 intronic 0.237655 0.6240530441945259 GWAS of prostate cancer rs2800221 1 247058705 247058705 intronic 0.059429 1.2260015774674502 GWAS of prostate cancer rs1613209 1 247035179 247035179 intronic 0.050538 1.29638194892482 GWAS of prostate cancer rs2642977 1 247092378 247092378 intronic 0.048204 1.3169169222207 GWAS of prostate cancer rs2800219 1 247055427 247055427 intronic 0.043923 1.35730800464744

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000153207.14 AHCTF1 610853