PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CCDC121 UBE2E3 26186194 biogrid exp P P P P P P P P GP P G P P P GP UBE2E3 MUL1 19690564,25224329 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G DET1 UBE2E3 17452440 biogrid exp G G G G G GP G G G G G G G GP G GP GP G G G GP G G GP GP G GP G G MDM2 UBE2E3 21965653 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G ZNRF1 UBE2E3 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RPS27A UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HUWE1 UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RNF10 UBE2E3 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G ARRDC1 UBE2E3 19549727 intact exp G GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G RNF111 UBE2E3 19549727,19690564 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CUL3 UBE2E3 19256485 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RDH12 26186194 biogrid exp G G G G G G G G G CADPS2 UBE2E3 19690564 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM37 UBE2E3 21143188 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G G GP G GP GP G HTT UBE2E3 23275563 biogrid,intact exp GP GP G G G GP G G GP G P G GP G GP GP GP G GP G G G GP G GP GP CEP192 UBE2E3 19549727 intact exp GP P G G GP G G GP G GP G G GP G GP GP GP G G P G G GP GP G GP GP G UBE2E3 TRIM39 25416956,19549727 biogrid,intact exp P P P P P P P UBE2E3 TBL1XR1 18202150 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G NKD2 UBE2E3 26186194 biogrid exp G GP G GP G G GP G GP G G GP G GP GP G G P G G GP GP G GP G G DTX3 UBE2E3 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G G G GP GP GP G G G G GP GP G GP GP G UBE2E3 ARID3A 15017387 hprd,biogrid exp GP G G G G GP G G G G GP G G GP G GP GP G G G GP G G GP GP G GP GP G HERC4 UBE2E3 22496338 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G GP G G DVL2 UBE2E3 19888210 i2d exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G MID1 UBE2E3 25416956,19549727,21143188 biogrid,intact exp G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G UBE2E3 BARD1 21965653 biogrid exp P G G P GP P GP G GP P G P G GP P G GP GP G DDB1 UBE2E3 17452440 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBA1 UBE2E3 17597759,22069333 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 UBA2 10187858 innatedb exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G G GP GP G GP GP G UBE2E3 OTUB1 unassigned1260 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G ZNRF4 UBE2E3 19690564 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G EEF1A1 UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TARDBP UBE2E3 24825905 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RPL14 UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UFL1 UBE2E3 19690564 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G G GP G GP GP G SPOP UBE2E3 19256485 biogrid exp G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP GP G UBE2E3 KLHL42 19256485 biogrid exp G G G G G GP G G GP G GP G G G G G GP GP G G GP G G G G G G GP G UBE2E3 MARCH5 16936636 biogrid exp G G G G G GP G G GP G GP G G G G G GP G G G G G G G G G G G G ANKRD20A12P UBE2E3 19549727 intact exp LSM8 UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G UBE2E3 TRIM45 21143188 biogrid exp G GP G G G GP G G G G G G G GP G G GP G G G GP G G GP G G G G G UBE2E3 NEDD4L 22496338 biogrid exp GP GP G GP G G GP G GP G G P G GP GP GP G G GP G G G GP G GP G FBXO25 UBE2E3 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF130 UBE2E3 19690564 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G NKD1 UBE2E3 19888210 i2d exp G G G G G P G G G G P GP ACVR1 UBE2E3 15761153 hprd,i2d exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 TRIM2 19549727 biogrid,intact exp GP G G GP G G GP G G G G G G G GP G G G G G G G G G G UBE2E3 RMND5B 19690564 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G MKRN3 UBE2E3 19549727 biogrid,intact exp P P P P P P P P P P P P P P TRIM27 UBE2E3 21143188 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBAP2L UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G ETV5 UBE2E3 26186194 biogrid exp GP GP G G G GP G G P G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 DDA1 17452440 biogrid exp GP GP G G G GP G G GP G GP G G G GP GP GP G GP G G GP GP G GP GP G CUL1 UBE2E3 19256485 biogrid exp GP G G G G GP G G GP G GP G G G G GP GP GP G G GP G G GP GP G GP GP G RANGAP1 UBE2E3 9920803 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBB UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNF166 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G TRIM50 UBE2E3 21143188 biogrid exp P P P P GP P P P P G P P GP GP SPRY2 UBE2E3 26186194 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G UBE2E3 RNF185 25416956,19549727 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G G G G GP G G GP GP G TRIM32 UBE2E3 21143188 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G NFE2L2 UBE2E3 20484052 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBC UBE2E3 19549727,22496338 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TBL1X UBE2E3 18202150 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CUL4A UBE2E3 19256485 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 MID2 21143188 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP GP G G GP G G GP GP G GP GP G MAGOH UBE2E3 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TRIM38 UBE2E3 21143188 biogrid exp GP GP G G P G G GP GP G G GP G GP GP GP G GP G G GP GP G GP P G UBE2E3 RNF114 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNF181 19690564 biogrid,intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G RCBTB2 UBE2E3 19256485 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RNF43 UBE2E3 19690564 biogrid,intact exp P GP P GP GP G P G GP P GP G G GP G G P GP GP GP G UBE2E3 AUP1 19549727 intact exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 AXIN2 19888210 i2d exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 SAE1 10187858 hprd exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 FSD1 26186194 biogrid exp P G GP G G P G P GP P P P P GP UFM1 UBE2E3 19690564 biogrid exp GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G ARIH2 UBE2E3 19549727 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RCBTB1 UBE2E3 19256485 biogrid exp, ortho G GP G G G GP G G GP G GP G G G G GP GP GP G G G G G GP GP G GP G G UBE2E3 IPO11 15545318,11809816, 25402006 hprd,biogrid exp, ortho, pred G UBE2E3 RNF25 19549727,19690564,24901938, 25402006 biogrid,intact exp, ortho, pred P G P P P P P P P P P G P P RNF220 UBE2E3 19549727, 25402006 intact exp, ortho, pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G GP G G GP G G UBE2E3 RNF5 25416956,19549727,15545318,14667819, 25402006, 23023127, 21836163 hprd,biogrid,i2d,mint,intact exp, ortho, pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G SIAH1 UBE2E3 11389839, 21836163 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RBX1 UBE2E3 17452440, 23023127 biogrid exp, pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G G GP G UBE2E3 STUB1 21518764, 23023127 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G ATXN1 UBE2E3 16713569, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G WWP2 UBE2E3 22496338, 23023127, 21836163, 16082366 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G UBOX5 UBE2E3 11274149, 23023127 hprd exp, pred GP GP G G G GP G G P G G G G GP G P GP G G G G G G P GP G GP G G UBE2E3 UBE2E3 19549727,20061386,20484052, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 ITCH 22496338, 23023127 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RNF165 UBE2E3 19690564, 23023127 biogrid,intact exp, pred P P G GP P G P G P P GP G P G G P G P P CHUK UBE2E3 9409737, 21836163 hprd exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNF115 19690564, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 RNF150 19690564, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G GP G GP GP G G G P G G G GP G GP GP G NFKBIA UBE2E3 9409737,9734360,10187858,10582246, 25402006, 21836163 innatedb,hprd,bci exp, pred G GP G G G GP G G GP G G G G GP G GP GP G G G GP G G GP GP G GP GP G BRCA1 UBE2E3 21965653,19712108,17873885, 23023127 biogrid exp, pred P P G G P P P P GP P P P P P P GP DTX3L UBE2E3 19549727, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RNF13 UBE2E3 19690564, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 HERC5 19549727, 16082366 intact exp, pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G TGFBR1 UBE2E3 15761153, 21836163 hprd,i2d exp, pred GP G G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G GP G G RNF8 UBE2E3 11322894, 21836163 hprd,biogrid exp, pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G GP GP G UBE2E3 RNF167 19690564,23414517, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G G G GP GP GP G G GP G G G GP G GP GP G RING1 UBE2E3 19549727, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 CHFR 19549727, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CNOT4 UBE2E3 11823428,19690564,15001359, 23023127, 21836163 hprd,biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNF14 11322894,19549727, 25402006, 23023127, 16082366 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RFWD3 UBE2E3 19549727, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G UBE2E3 RNF2 19549727, 23023127 biogrid,intact exp, pred P P GP P P P P P P P P RNF4 UBE2E3 19549727, 25402006, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP G G G G G GP GP G G GP G G GP G G GP GP G UBR5 UBE2E3 19549727, 16082366 intact exp, pred GP G G G G GP G G GP G GP G G GP G G GP G G G GP G G G G G GP GP G DZIP3 UBE2E3 19549727, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G P G G GP GP G GP GP G UBE2E3 RNF11 19549727, 25402006, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2L6 UBE2E3 23023127 bci exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G SUMO4 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G G GP GP G G GP G G GP G G GP GP G PCMT1 UBE2E3 21836163 pred GP GP G G G GP G G G G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 UBQLN2 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2D2 UBE2E3 25402006, 23023127 pred GP G G G G GP G G GP G GP G G GP G G GP GP G G GP G G GP G G GP GP G CNOT3 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G UBE3A UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNFT2 23023127 pred P P G GP G P G P P P GP G P P P P UBTD2 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G UBE2E3 BIRC6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PIN1 UBE2E3 23023127 pred G GP G G G GP G G GP G G G G GP G G GP G G P G G G G G GP GP G UBE2G2 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G G GP G GP GP G UBE2E3 RNF19A 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2D1 UBE2E3 25402006, 23023127 pred GP G G G G GP G G GP G GP G G GP G G GP GP G G GP G G GP G G GP GP G UBE2E3 ATG3 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G G GP G GP GP G RPS3 UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G G GP G GP GP G HERC2 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE4A UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE3B UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RNF144B UBE2E3 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP GP G G GP G G G GP G G GP G CCR4 UBE2E3 21836163 pred G G P G G P P P GP G G G GP G G P P P G UBE2K UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 G3BP2 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 UHRF2 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G NDUFB5 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2U UBE2E3 23023127 pred P P P P P P P P P P P P P GP RFPL4B UBE2E3 23023127 pred P P P P P P P P UBE2E3 UBE2T 25402006, 23023127 pred G G G GP G GP P P GP GP GP G GP P GP G UBE2E3 DNAJA3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2J2 UBE2E3 23023127 pred G G G G G G G G GP G G G G G G GP G G G G GP G G GP GP G G G G UBE2E3 UBL7 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G TRIM75P UBE2E3 23023127 pred UBE2E3 UFC1 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G UBE2L3 UBE2E3 23023127 pred GP G G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G UBE2E3 PRPF19 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 HECW2 16082366 pred GP GP G G G GP G G GP G GP G G G G P GP P G G GP G G GP GP G GP GP NEDD4 UBE2E3 16082366 pred GP GP G G P G G GP GP G G GP G GP GP GP G G GP G G GP GP G GP P G ARAF UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN2B UBE2E3 23023127 pred G GP G G G G G G GP G GP G G G G GP G GP G G G G G G GP G GP GP G BTG2 UBE2E3 21836163 pred GP G G G G GP G G G G GP G G G G G GP G G G GP G G G G G G GP G LAMTOR5 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 WWP1 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 CNOT8 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G PXN UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G G GP G HECW1 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP P GP G UBE2M UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2Q1 UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYLIP UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2I UBE2E3 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G SMAD3 UBE2E3 25402006 pred GP GP G G G GP G G G G G G G GP G G GP G G G GP G G G G G G G G GLO1 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G G G G G GP G GP GP G UBL4B UBE2E3 23023127 pred P P P P P P P P P P P P P UBFD1 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 SENP2 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HERC1 UBE2E3 21836163, 16082366 pred G G G G G G G G G G G G G GP G G G G G G G G G G G G G G G UBE2E3 TRIM17 23023127 pred P P P P P P P P P P P P P GP PIK3CA UBE2E3 23023127 pred GP GP G GP G G GP G GP G G GP G P GP GP G G P G G GP GP G GP GP UBE2E3 NCOR2 21836163 pred GP GP G G G GP G G GP G GP G G G G GP GP GP G G GP G G G GP G GP GP G RNF151 UBE2E3 23023127 pred P G G G GP G GP GP G P G GP G G P GP G G GP UBE2C UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G ZNRF2 UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G UBE2A UBE2E3 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBLCP1 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RELA UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G RAD23B UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G NEDD8 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G AXIN1 UBE2E3 25402006 pred GP GP G G GP G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 ATG5 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G SKP1 UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G UBE2E3 NSFL1C 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G ARF4 UBE2E3 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 ZNF335 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 UBQLN3 16082366 pred G G G G G G GP G UBE2E1 UBE2E3 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 CNOT2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBC UBE2E3 23023127 pred TRIP12 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HECTD2 UBE2E3 16082366 pred GP GP G GP G G GP G GP G G GP G GP GP GP G GP G G GP GP G GP GP G SUMO3 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2F UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G NFKBIB UBE2E3 25402006 pred GP P G G GP G G P G GP G G GP G GP GP P G G GP G G GP GP G GP GP G UBE2E3 ANAPC10 23023127 pred GP G G G G GP G G GP G GP G G GP G GP GP G G G G G G GP GP G GP GP G NHLRC1 UBE2E3 23023127 pred RAG1 UBE2E3 23023127 pred UBE2D3 UBE2E3 25402006, 23023127 pred GP G G G G GP G G GP G GP G G GP G G GP GP G G GP G G GP G G GP GP G UBE2E3 SMURF2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF139 UBE2E3 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP GP G G GP G G GP GP G GP GP G COPS5 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G SUMO2 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TRAF2 UBE2E3 23023127 pred P P P P P P P P P P P P G GP P UBE2G1 UBE2E3 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 FBXW11 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCLK1 UBE2E3 23023127 pred G G G GP G G GP G GP G GP GP GP G G P G G G GP G GP P G UBE2E3 CNOT6 21836163 pred G G G G G GP G G GP G G G G G G GP GP G G G G G G G GP G GP G G UBE2V2 UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 HECTD1 16082366 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G UBE2R2 UBE2E3 23023127 pred G G G G G G G G G G G G G GP G G G G G G G G G G G G GP G G UBE2S UBE2E3 23023127 pred G G G G G G G G GP G G G GP G G G G G G G G G G G GP G CBLB UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G G GP G GP GP G HERC6 UBE2E3 16082366 pred G G G GP G G GP G GP G G GP G G GP G G G GP G G G G G G G G PARK2 UBE2E3 23023127 pred P GP G GP G G GP G GP G P GP GP G P G GP GP P GP G WDSUB1 UBE2E3 23023127 pred G G G G G G G G G G GP G G G G G G G G G G G G G G G G GP G MAP3K1 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2N UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G UBE2E3 UBE2W 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G AR UBE2E3 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G BAG6 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CDC34 UBE2E3 25402006, 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 RNF41 23023127 pred GP GP G G G GP G G GP G GP G G GP GP P G P G GP GP G GP P CNOT1 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CAND2 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G G G GP GP GP G G P G G GP GP G GP GP G UBE2Q2 UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF135 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G RNF182 UBE2E3 23023127 pred P G G G GP P G P G P P GP P G G GP P GP UBE2E3 UBQLN1 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE3C UBE2E3 16082366 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G PARN UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2V1 UBE2E3 23023127 pred UBE2E3 ANAPC11 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HECTD3 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G BMI1 UBE2E3 23023127 pred P P P P P P P P P P P P P P NR4A2 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G P G G GP GP G GP P G UBE2H UBE2E3 25402006, 23023127 pred GP GP G G G GP G G G G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2NL UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2E3 RCHY1 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G GP G G CHAF1B UBE2E3 21836163 pred P P GP G P P GP UBL4A UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP P G UBE2E3 SMURF1 21836163, 16082366 pred G GP G G G GP G G GP G GP G G G G G GP GP G G GP G G G G G G GP G HOXA1 UBE2E3 21836163 pred P P P P P P P P P P P UBA3 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TMEM173 UBE2E3 25402006 pred GP G G G G GP G G GP G G G G GP G G GP G G G GP G G G G G GP GP G UBE2E3 TOPORS 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G SKIL UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G UBE2E3 UBTD1 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP GP G G P G GP G G G GP G SUMO1 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CBL UBE2E3 23023127 pred G GP G G G GP G G GP G GP G G GP G G GP GP G G G G G G G G G GP G UBE2B UBE2E3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HDAC3 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G HERC3 UBE2E3 16082366 pred GP GP G G G GP G G GP G GP G GP G GP GP G P G G GP P G GP P G UBE2E3 UBE2E2 25402006, 23023127, 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G AREL1 UBE2E3 16082366 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G GP G G G G G UBE2E3 HDAC6 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G HACE1 UBE2E3 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM13 UBE2E3 23023127 pred GP GP G G G GP G G GP G G G G G G GP GP G G G G G G GP GP G GP GP G UBXN1 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TRAF7 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G UBE2E3 RNF6 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP G G G GP G GP GP G UBE2E3 HDAC5 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2E3 UBE2D4 25402006, 23023127 pred GP G G G G GP G G GP G GP G G GP G G GP GP G G GP G G GP G G GP GP G SLC25A5 UBE2E3 25402006 pred G GP G G G GP G G G G GP G G G G GP GP G G G G G G G GP G GP GP G RNF103 UBE2E3 23023127 pred G GP G G G GP G G GP G GP G G GP G GP GP GP G G G G G G GP G GP GP G BIRC2 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G RNF175 UBE2E3 23023127 pred GP P G G G GP G G GP G G P GP G G P G G P GP P GP SMAD7 UBE2E3 25402006 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP P G STAU1 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G TAF7 UBE2E3 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G TRIM40 UBE2E3 23023127 pred P P P P P P P P P GP P P P P RBBP6 UBE2E3 23023127 pred GP G G G G GP G G GP G GP G G G G GP GP G G G GP G G G GP G GP GP G UBE2E3 FHOD1 25402006 pred G GP G G G G G G GP G G G G GP G G G GP G G G G G GP G G G GP G UBE2E3 TRAF6 23023127 pred GP GP G G G G G G GP G GP G G G G GP G GP G G GP G G G GP G GP GP G CAND1 UBE2E3 21836163 pred G GP G G G G G G GP G GP G G G G GP G GP G G G G G GP GP G G GP G UBE2E3 AKTIP 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q969T4 A0A024RCQ4 - 14667819 - X 2 Q9NX47 Q969T4 pull down 16936636 direct interaction X 2 O43567 Q969T4 two hybrid 19690564 direct interaction X 2 Q969T4 Q9UJV3 two hybrid 21143188 direct interaction X 2 Q969T4 Q9UJV3 two hybrid 21143188 direct interaction X 2 Q969T4 P14373 two hybrid 21143188 direct interaction X 2 Q969T4 A0A024R843 two hybrid 21143188 direct interaction X 2 Q969T4 A0A024R843 two hybrid 21143188 direct interaction X 2 Q969T4 P14373 two hybrid 21143188 direct interaction X 2 Q969T4 two hybrid 21143188 direct interaction X 2 Q969T4 two hybrid 21143188 direct interaction X 2 Q969T4 A0A024QZY4 two hybrid 21143188 direct interaction X 2 Q969T4 Q16531 affinity chromatography technology 17452440 physical association X 2 Q969T4 P0CG48 affinity chromatography technology 17452440 physical association X 2 Q969T4 A0A024RCQ4 two hybrid 15545318 direct interaction X 2 Q969T4 Q16236-3 pull down 20484052 direct interaction X 2 Q969T4 Q16236-3 affinity chromatography technology 20484052 physical association X 2 Q969T4 P0CG48 enzymatic study 22496338 direct interaction X 2 Q969T4 Q99856 affinity chromatography technology 15017387 physical association X 2 Q969T4 Q99856 two hybrid 15017387 direct interaction X 2 Q969T4 A0A024R475 pull down 19256485 direct interaction X 2 Q969T4 O95199 pull down 19256485 direct interaction X 2 Q969T4 B2RNT7 pull down 19256485 direct interaction X 2 Q969T4 O43791 pull down 19256485 direct interaction X 2 Q969T4 Q9UBS8 pull down 11322894 direct interaction X 2 Q969T4 pull down 22496338 direct interaction X 2 Q969T4 B7Z2P9 pull down 22496338 direct interaction X 2 Q969T4 B4DHF6 pull down 22496338 direct interaction X 2 Q969T4 Q99728 pull down 21965653 direct interaction X 2 Q969T4 pull down 21965653 direct interaction X 2 Q969T4 Q00987 pull down 21965653 direct interaction X 2 Q969T4 P0CG48 affinity chromatography technology 21963094 physical association X 2 Q969T4 P0CG48 affinity chromatography technology 20639865 physical association X 2 Q969T4 P0CG48 affinity chromatography technology 22053931 physical association X 2 Q969T4 P0CG48 affinity chromatography technology 23000965 physical association X 2 Q969T4 A0A024RAA0 two hybrid 25224329 direct interaction X 2 Q969T4 A0A024RCQ4 two hybrid 25416956 direct interaction X 2 Q969T4 A0A024RCP5 two hybrid 25416956 direct interaction X 2 Q969T4 Q9UBS8 two hybrid 11322894 direct interaction X 2 Q969T4 Q8IUQ4 two hybrid 11389839 direct interaction X 2 Q969T4 P61960 two hybrid 19690564 direct interaction X 2 Q969T4 A0A024RAA0 two hybrid 19690564 direct interaction X 2 Q969T4 two hybrid 19690564 direct interaction X 2 Q969T4 Q9P0P0 two hybrid 19690564 direct interaction X 2 Q969T4 A0A024R5T5 two hybrid 19690564 direct interaction X 2 Q969T4 Q6ZSG1 two hybrid 19690564 direct interaction X 2 Q969T4 Q68DV7 two hybrid 19690564 direct interaction X 2 Q969T4 Q9Y4L5 two hybrid 19690564 direct interaction X 2 Q969T4 A0A024RCQ4 two hybrid 19549727 direct interaction X 2 Q969T4 Q8ND25 two hybrid 19549727 direct interaction X 2 Q969T4 Q9Y3C5 two hybrid 19549727 direct interaction X 2 Q969T4 Q8TDB6 two hybrid 19549727 direct interaction X 2 Q969T4 Q86Y13 two hybrid 19549727 direct interaction X 2 Q969T4 A0A024RCP5 two hybrid 19549727 direct interaction X 2 Q969T4 A0A024RBP0 two hybrid 19549727 direct interaction X 2 Q969T4 P78317 two hybrid 19549727 direct interaction X 2 Q969T4 Q06587 two hybrid 19549727 direct interaction X 2 Q969T4 A0A024RB96 two hybrid 19549727 direct interaction X 2 Q969T4 Q9UBS8 two hybrid 19549727 direct interaction X 2 Q969T4 Q13064 two hybrid 19549727 direct interaction X 2 Q969T4 A0A024R5T5 two hybrid 19549727 direct interaction X 2 Q969T4 Q96A37-2 two hybrid 19549727 direct interaction X 2 Q969T4 Q9BZK7 affinity chromatography technology 18202150 physical association X 2 Q969T4 two hybrid 19712108 direct interaction X 2 Q969T4 x-ray crystallography 19712108 association X 2 Q969T4 pull down 19712108 direct interaction X 2 Q969T4 two hybrid 17873885 direct interaction X 2 Q969T4 P0CG48 affinity chromatography technology 21139048 physical association X 2 Q969T4 P0CG48 affinity chromatography technology 21906983 physical association X 2 Q969T4 two hybrid 21143188 direct interaction X 2 Q969T4 two hybrid 21143188 direct interaction X 2 Q969T4 O94972 two hybrid 21143188 direct interaction X 2 Q969T4 O94972 two hybrid 21143188 direct interaction X 2 Q969T4 Q9H8W5-2 two hybrid 21143188 direct interaction X 2 Q969T4 Q9BW61 affinity chromatography technology 17452440 physical association X 2 Q969T4 Q7L5Y6-2 affinity chromatography technology 17452440 physical association X 2 Q969T4 Q7L5Y6-2 affinity chromatography technology 17452440 physical association X 2 Q969T4 Q7L5Y6-2 affinity chromatography technology 17452440 physical association X 2 Q969T4 Q9BW61 biochemical 17452440 colocalization X 2 Q969T4 A0A024R1A3 enzymatic study 22069333 direct interaction X 2 Q969T4 Q9UI26 two hybrid 15545318 direct interaction X 2 Q969T4 Q9UI26 pull down 15545318 direct interaction X 2 Q969T4 Q9UI26 pull down 15545318 direct interaction X 2 Q969T4 Q969T4 enzymatic study 20484052 direct interaction X 2 Q969T4 O95628-8 two hybrid 15001359 direct interaction X 2 Q969T4 O95628-8 two hybrid 11823428 direct interaction X 2 Q969T4 P34909 two hybrid 11823428 direct interaction X 2 Q969T4 Q8NDN9 pull down 19256485 direct interaction X 2 Q969T4 A0A090N7U0 pull down 19256485 direct interaction X 2 Q969T4 B2RBV7 pull down 19256485 direct interaction X 2 Q969T4 Q96FF1 two hybrid 16713569 direct interaction X 2 Q969T4 O76064 pull down 11322894 direct interaction X 2 Q969T4 Q96J02-2 pull down 22496338 direct interaction X 2 Q969T4 P42858 two hybrid 23275563 direct interaction X 2 Q969T4 A0A024R4E2 two hybrid 24825905 direct interaction X 2 Q969T4 A0A024R4E2 affinity chromatography technology 24825905 physical association X 2 Q969T4 A0A024R1A3 pull down 17597759 direct interaction X 2 Q969T4 Q96BH1 pull down 24901938 direct interaction X 2 Q969T4 Q96BH1 enzymatic study 24901938 direct interaction X 2 Q969T4 Q969T4 enzymatic study 20061386 direct interaction X 2 Q969T4 two hybrid 25416956 direct interaction X 2 Q969T4 A0A024R1F5 two hybrid 25416956 direct interaction X 2 Q969T4 Q9BW61 affinity chromatography technology 17452440 physical association X 2 Q969T4 P62877 pull down 17452440 direct interaction X 2 Q969T4 A0A024R1U0 enzymatic study 9920803 direct interaction X 2 Q969T4 O76064 two hybrid 11322894 direct interaction X 2 Q969T4 P25963 two hybrid 9409737 direct interaction X 2 Q969T4 O95628-8 two hybrid 19690564 direct interaction X 2 Q969T4 Q96G75 two hybrid 19690564 direct interaction X 2 Q969T4 Q86XS8 two hybrid 19690564 direct interaction X 2 Q969T4 Q9ULK6 two hybrid 19690564 direct interaction X 2 Q969T4 Q9H6Y7 two hybrid 19690564 direct interaction X 2 Q969T4 Q96BH1 two hybrid 19690564 direct interaction X 2 Q969T4 Q8WWF5 two hybrid 19690564 direct interaction X 2 Q969T4 Q9Y508 two hybrid 19549727 direct interaction X 2 Q969T4 A0A024R1F5 two hybrid 19549727 direct interaction X 2 Q969T4 Q99496 two hybrid 19549727 direct interaction X 2 Q969T4 Q96BH1 two hybrid 19549727 direct interaction X 2 Q969T4 Q96EP1-4 two hybrid 19549727 direct interaction X 2 Q969T4 O95376 two hybrid 19549727 direct interaction X 2 Q969T4 two hybrid 19549727 direct interaction X 2 Q969T4 Q6PCD5 two hybrid 19549727 direct interaction X 2 Q969T4 Q9C040 two hybrid 19549727 direct interaction X 2 Q969T4 O60907-2 affinity chromatography technology 18202150 physical association X 2 Q969T4 Q9UNE7 pull down 21518764 direct interaction X 2 Q969T4 D3DPA4 in vivo 15761153 - X 2 Q969T4 P36897-3 in vivo 15761153 - X 2 Q969T4 O15111 two hybrid 9409737 - X 2 Q969T4 A0A024RCQ4 two hybrid 14667819 - X 2 Q969T4 O15111 two hybrid 9409737 - X 2 Q969T4 O94941-2 two hybrid 11274149 - X 2 Q969T4 A0A024R0R4 in vivo 10187858 - X 2 Q969T4 A0A024R0R4 in vitro 10187858 - X 2 Q969T4 D3DPA4 in vivo 15761153 - X 2 Q969T4 P36897-3 in vivo 15761153 - X 2 Q969T4 Q99856 in vitro 15017387 - X 2 Q969T4 Q99856 two hybrid 15017387 - X 2 Q969T4 Q99856 in vivo 15017387 - X 2 Q969T4 A0A024RCQ4 two hybrid 14667819 - X 2 Q969T4 O76064-3 two hybrid 11322894 - X 2 Q969T4 Q99856 in vivo 15017387 - X 2 Q969T4 Q99856 in vitro 15017387 - X 2 Q969T4 Q99856 two hybrid 15017387 - X 2 Q969T4 O76064-3 two hybrid 11322894 - X 2 Q969T4 O94941-2 two hybrid 11274149 - X 2 Q969T4 A0A024R0R4 in vivo 10187858 - X 2 Q969T4 A0A024R0R4 in vitro 10187858 - X 2 Q969T4 two hybrid 10582246,9409737,9734360 - X 2 Q969T4 in vitro 10582246,9409737,9734360 - X 2 Q969T4 P54253 two hybrid 16713569 - X 2 Q969T4 A0A024R776 two hybrid 15001359 - X 2 Q969T4 in vitro 10582246,9409737,9734360 - X 2 Q969T4 two hybrid 10582246,9409737,9734360 - X 2 Q969T4 P54253 two hybrid 16713569 - X 2 Q969T4 Q9UI26-2 two hybrid 11809816 - X 2 Q969T4 Q9UI26-2 in vitro 11809816 - X 2 Q969T4 A0A024R776 two hybrid 15001359 - X 2 Q969T4 Q9UI26-2 in vitro 11809816 - X 2 Q969T4 Q9UI26-2 two hybrid 11809816 - X 2 O43567 Q969T4 two hybrid array 19690564 physical association X 2 Q969T4 A0A024RCQ4 two hybrid 14667819 physical association X 2 Q969T4 Q9Y679 two hybrid 19549727 physical association X 2 Q969T4 P0CG47 two hybrid 19549727 physical association X 2 Q969T4 P68104 two hybrid 19549727 physical association X 2 Q969T4 P50914 two hybrid 19549727 physical association X 2 Q969T4 Q9UII4 two hybrid 19549727 physical association X 2 Q969T4 Q8TEP8 two hybrid 19549727 physical association X 2 Q969T4 Q8N5I2 two hybrid 19549727 physical association X 2 Q969T4 A0A024RCQ4 two hybrid array 19549727 physical association X 2 Q969T4 Q86Y13 two hybrid array 19549727 physical association X 2 Q969T4 A0A024RBP0 two hybrid array 19549727 physical association X 2 Q969T4 Q9Y3C5 two hybrid array 19549727 physical association X 2 Q969T4 A0A024RCP5 two hybrid array 19549727 physical association X 2 Q969T4 Q8ND25 two hybrid array 19549727 physical association X 2 Q969T4 Q8TDB6 two hybrid array 19549727 physical association X 2 Q969T4 A0A024RBV4 two hybrid array 19549727 physical association X 2 Q969T4 Q06587 two hybrid array 19549727 physical association X 2 Q969T4 P78317 two hybrid array 19549727 physical association X 2 Q969T4 Q13064 two hybrid array 19549727 physical association X 2 Q969T4 Q9UBS8 two hybrid array 19549727 physical association X 2 Q969T4 Q6ZNA4 two hybrid array 19549727 physical association X 2 Q969T4 Q96A37 two hybrid array 19549727 physical association X 2 Q969T4 A0A024RB96 two hybrid array 19549727 physical association X 2 Q969T4 O94874 two hybrid array 19690564 physical association X 2 Q969T4 A0A024RAA0 two hybrid array 19690564 physical association X 2 Q969T4 Q86UW7 two hybrid array 19690564 physical association X 2 Q969T4 Q9P0P0 two hybrid array 19690564 physical association X 2 Q969T4 Q6ZNA4 two hybrid array 19690564 physical association X 2 Q969T4 Q6ZSG1 two hybrid array 19690564 physical association X 2 Q969T4 Q68DV7 two hybrid array 19690564 physical association X 2 Q969T4 Q9Y4L5 two hybrid array 19690564 physical association X 2 Q969T4 Q99PZ6 pull down 24446487 physical association X 2 Q969T4 A0A024RBV4 two hybrid prey pooling approach 25416956 physical association X 2 Q969T4 A0A024RCQ4 two hybrid prey pooling approach 25416956 physical association X 2 Q969T4 A0A024RCP5 two hybrid prey pooling approach 25416956 physical association X 2 Q969T4 A0A024RBV4 two hybrid array 25416956 physical association X 2 Q969T4 A0A024RCQ4 two hybrid array 25416956 physical association X 2 Q969T4 A0A024RCP5 two hybrid array 25416956 physical association X 2 Q969T4 A0A024RBV4 validated two hybrid 25416956 physical association X 2 Q969T4 A0A024RCP5 validated two hybrid 25416956 physical association X 2 Q969T4 A0A024RCQ4 validated two hybrid 25416956 physical association X 2 Q5VTB9 Q969T4 two hybrid 19549727 physical association X 2 Q969T4 P54253 two hybrid 16713569 physical association X 2 Q969T4 P61326 two hybrid 19549727 physical association X 2 Q969T4 B2RDW1 two hybrid 19549727 physical association X 2 Q969T4 A8CGI2 two hybrid 19549727 physical association X 2 Q969T4 A0A024R9W5 two hybrid 19549727 physical association X 2 Q969T4 Q14157 two hybrid 19549727 physical association X 2 Q969T4 O95071 two hybrid 19549727 physical association X 2 Q969T4 A4D0W0 two hybrid 19549727 physical association X 2 Q969T4 Q8NF67 two hybrid 19549727 physical association X 2 Q969T4 Q99496 two hybrid array 19549727 physical association X 2 Q969T4 Q9Y508 two hybrid array 19549727 physical association X 2 Q969T4 Q96BH1 two hybrid array 19549727 physical association X 2 Q969T4 A0A024R1F5 two hybrid array 19549727 physical association X 2 Q969T4 O95376 two hybrid array 19549727 physical association X 2 Q969T4 Q9C040 two hybrid array 19549727 physical association X 2 Q969T4 Q6PCD5 two hybrid array 19549727 physical association X 2 Q969T4 A0A024R785 two hybrid array 19690564 physical association X 2 Q969T4 Q96G75 two hybrid array 19690564 physical association X 2 Q969T4 Q86XS8 two hybrid array 19690564 physical association X 2 Q969T4 Q9ULK6 two hybrid array 19690564 physical association X 2 Q969T4 Q9H6Y7 two hybrid array 19690564 physical association X 2 Q969T4 Q96BH1 two hybrid array 19690564 physical association X 2 Q969T4 Q8WWF5 two hybrid array 19690564 physical association X 2 Q969T4 P42858 two hybrid prey pooling approach 23275563 physical association X 2 Q969T4 Q9H6Y7 two hybrid fragment pooling approach 23414517 physical association X 2 Q969T4 A0A024R1F5 two hybrid prey pooling approach 25416956 physical association X 2 Q969T4 A0A024R1F5 two hybrid array 25416956 physical association X 2 Q969T4 A0A024R1F5 validated two hybrid 25416956 physical association X 2 Q96EP1 Q969T4 two hybrid array 19549727 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B DET1 UBE2E3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17452440 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_196055|BIOGRID_196048|BIOGRID_196065|BIOGRID_196061 bait|bait|bait|prey prey|prey|prey|bait NFE2L2 UBE2E3 MI:0096(pull down)|MI:0096(pull down) 20484052 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_207388|BIOGRID_207395 prey|prey bait|bait UFM1 UBE2E3 MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_123557 prey bait DTX3L UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124118|UniProt_101141 prey|prey bait|bait RNF220 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100891 prey bait RPL14 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100885 prey bait UBE2E3 MUL1 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102548|BIOGRID_123558 bait|bait prey|prey RNF111 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(intact) UniProt_102552|BIOGRID_124477|BIOGRID_123563|UniProt_101428 prey|prey|prey|prey bait|bait|bait|bait UBE2E3 TRIM39 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101137|BIOGRID_124157 bait|bait prey|prey UBE2E3 UBC MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100846 bait prey UBE2E3 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194312 prey bait UBE2E3 RNF167 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0663(confocal microscopy) 19690564,23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact) UniProt_102557|BIOGRID_123568|UniProt_127348 bait|bait|prey prey|prey|bait UBB UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100845 prey bait UFL1 UBE2E3 MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_102546 prey bait TGFBR1 UBE2E3 MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_18070 - - RFWD3 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124467|UniProt_101430 prey|prey bait|bait RCBTB1 UBE2E3 MI:0096(pull down) 19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_214476 prey bait UBE2E3 RNF181 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123561|UniProt_102550 bait|bait prey|prey RNF10 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101134|BIOGRID_124173 prey|prey bait|bait UBE2E3 NEDD4L MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226056 prey bait UBE2E3 KLHDC5 MI:0096(pull down) 19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_214478 bait prey UBE2E3 ITCH MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226068 prey bait UBE2E3 RNF185 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101138|BIOGRID_124195 bait|bait prey|prey RNF13 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102553|BIOGRID_123564 prey|prey bait|bait RNF8 UBE2E3 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 11322894 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_12912|BIOGRID_92735|BIOGRID_221445 -|prey|bait -|bait|prey CADPS2 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102549|BIOGRID_123559 prey|prey bait|bait UBA1 UBE2E3 MI:0415(enzymatic study) 22069333 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_197078 bait prey UBE2E3 RNF166 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101431|BIOGRID_124494 bait|bait prey|prey DZIP3 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124125|UniProt_101131 prey|prey bait|bait UBE2E3 RNF25 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(biogrid) UniProt_101136|UniProt_102558|BIOGRID_123569|BIOGRID_124211 bait|bait|bait|bait prey|prey|prey|prey CUL3 UBE2E3 MI:0096(pull down) 19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_214468 prey bait UBE2E3 CHFR MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101432|BIOGRID_124368 bait|bait prey|prey UBE2E3 RMND5B MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102551|BIOGRID_123562 bait|bait prey|prey EEF1A1 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100884 prey bait CEP192 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100890 prey bait UBE2E3 RNF114 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124088|UniProt_101135 bait|bait prey|prey UBE2E3 RNF115 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102559|BIOGRID_123571 bait|bait prey|prey ARIH2 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101426|BIOGRID_124377 prey|prey bait|bait UBE2E3 AUP1 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100841 bait prey ACVR1 UBE2E3 MI:0493(in vivo) 15761153 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17243 - - UBOX5 UBE2E3 MI:0018(two hybrid) 11274149 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12913 - - UBE2E3 RPS27A MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100844 bait prey UBE2E3 SIRT5 MI:0004(affinity chromatography technology) 22318606 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0796(suppressive genetic interaction defined by inequality) (biogrid) BIOGRID_193502 prey bait UBR5 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100888 prey bait CUL1 UBE2E3 MI:0004(affinity chromatography technology)|MI:0096(pull down) 17452440,19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_196067|BIOGRID_214487 prey|prey bait|bait UBE2E3 RNF11 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124097|UniProt_101133 bait|bait prey|prey RCBTB2 UBE2E3 MI:0096(pull down) 19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_214477 prey bait RING1 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101424|BIOGRID_124302 prey|prey bait|bait TBL1X UBE2E3 MI:0096(pull down) 18202150 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_134830 bait prey UBE2E3 RNF2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101129|BIOGRID_124203 bait|bait prey|prey UBE2E3 RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102555|BIOGRID_123566 bait|bait prey|prey UBE2E3 HERC5 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100886 bait prey UBE2E3 BARD1 MI:0096(pull down) 21965653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226139 prey bait UBE2E3 MID2 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194197|BIOGRID_194205 prey|bait bait|prey HERC4 UBE2E3 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226052 bait prey UBE2E3 STUB1 MI:0096(pull down) 21518764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_160917 prey bait CHUK UBE2E3 MI:0018(two hybrid) 9409737 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_7509 - - UBE2E3 RNF14 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 11322894,19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid)|(biogrid) BIOGRID_221449|UniProt_101427|BIOGRID_92734|BIOGRID_124331 prey|bait|bait|bait bait|prey|prey|prey UBE2E3 SAE1 MI:0493(in vivo) 10187858 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12914 - - TRIM32 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194245|BIOGRID_194251 bait|prey prey|bait UBE2E3 ARID3A MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15017387 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_30707|BIOGRID_212399|BIOGRID_212389 -|prey|prey -|bait|bait UBE2E3 IPO11 MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 11809816,15545318 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_12911|BIOGRID_197158|BIOGRID_197154|BIOGRID_197172 -|bait|prey|prey -|prey|bait|bait UBE2E3 ZNRF4 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102561|BIOGRID_123572 bait|bait prey|prey UBE2E3 RNF5 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14667819,15545318,19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint) MINT_61795|MINT_32974|MINT_61968|UniProt_73579|MINT_61892|BIOGRID_124053|HPRD_11277|UniProt_101132|MINT_32877|BIOGRID_197155|MINT_33050 prey|prey|prey|prey|prey|bait|-|bait|prey|prey|prey bait|bait|bait|bait|bait|prey|-|prey|bait|bait|bait CNOT4 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 11823428,15001359,19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) UniProt_102547|BIOGRID_207696|BIOGRID_123560|HPRD_30770|BIOGRID_207662 prey|bait|prey|-|bait bait|prey|bait|-|prey HTT UBE2E3 -|MI:0018(two hybrid) 23275563 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_126518|BIOGRID_251060 bait|bait prey|prey DDB1 UBE2E3 MI:0004(affinity chromatography technology) 17452440 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_196062 prey bait DTX3 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124317|UniProt_101435 prey|prey bait|bait MID1 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19549727,21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid)|(biogrid) BIOGRID_194237|UniProt_101422|BIOGRID_194229|BIOGRID_124418 bait|prey|prey|prey prey|bait|bait|bait MKRN3 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101425|BIOGRID_124424 prey|prey bait|bait UBC UBE2E3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17452440,20639865,21139048,21906983,21963094,22053931,22496338,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_266544|BIOGRID_264527|BIOGRID_211529|BIOGRID_196063|BIOGRID_169573|BIOGRID_266707|BIOGRID_178875|BIOGRID_268227 bait|bait|prey|prey|bait|bait|bait|bait prey|prey|bait|bait|prey|prey|prey|prey SIAH1 UBE2E3 MI:0018(two hybrid) 11389839 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_106500 bait prey TRIM50 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194271|BIOGRID_194264 prey|bait bait|prey MAGOH UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100843 prey bait UBAP2L UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100887 prey bait uniprotkb:(gene name) UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100893 prey bait RNF130 UBE2E3 MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_123565 prey bait uniprotkb:(gene name) UBE2E3 MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_102554 prey bait UBE2E3 DDA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17452440 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid) BIOGRID_196039|BIOGRID_196064 prey|bait bait|prey RNF43 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102560|BIOGRID_123570 prey|prey bait|bait UBE2E3 TBL1XR1 MI:0096(pull down) 18202150 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_134829 prey bait ZNRF1 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124078|UniProt_101139 prey|prey bait|bait MDM2 UBE2E3 MI:0096(pull down) 21965653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226151 bait prey UBE2E3 TRIM2 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124528|UniProt_101429 bait|bait prey|prey RNF165 UBE2E3 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102556|BIOGRID_123567 prey|prey bait|bait TRIM38 UBE2E3 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194305 bait prey WWP2 UBE2E3 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226063 bait prey BRCA1 UBE2E3 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 17873885,19712108,21965653 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_226145|BIOGRID_164366|BIOGRID_164373|BIOGRID_164346|BIOGRID_164356 bait|bait|bait|bait|bait prey|prey|prey|prey|prey ARRDC1 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100894 prey bait SPOP UBE2E3 MI:0096(pull down) 19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_214479 prey bait NAA38 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100889 prey bait CUL4A UBE2E3 MI:0096(pull down)|MI:0004(affinity chromatography technology) 17452440,19256485 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_214488|BIOGRID_196066 prey|prey bait|bait TRIM37 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194295|BIOGRID_194289 prey|bait bait|prey TRIM27 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194257|BIOGRID_194242 prey|bait bait|prey ATXN1 UBE2E3 MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(intact) MINT_82805|HPRD_12847|MINT_50517|BIOGRID_215634|UniProt_86190 bait|-|bait|bait|bait prey|-|prey|prey|prey HUWE1 UBE2E3 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100847 prey bait RNF4 UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124274|UniProt_101423 prey|prey bait|bait NFKBIA UBE2E3 MI:0018(two hybrid)|MI:0018(two hybrid) 9409737 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_77432|HPRD_38215 bait|- prey|-

PPI - HINT Gene A Gene B PMID Method Quality SPRY2 UBE2E3 26186194 0004 HT BRCA1 UBE2E3 21965653,19712108,19712108,19712108 0096,0018,0114,0096 LC ETV5 UBE2E3 26186194 0004 HT MDM2 UBE2E3 24980433,21965653 0096,0096 LC CCDC121 UBE2E3 26186194 0004 HT FBXO25 UBE2E3 26186194 0004 HT NKD2 UBE2E3 26186194 0004 HT UBE2E3 RNF25 26475854,24901938,24901938 0096,0415,0096 LC UBE2E3 RDH12 26186194 0004 HT UBE2E3 FSD1 26186194 0004 HT SPRY2 UBE2E3 26186194 0004 HT ETV5 UBE2E3 26186194 0004 HT CCDC121 UBE2E3 26186194 0004 HT FBXO25 UBE2E3 26186194 0004 HT NKD2 UBE2E3 26186194 0004 HT UBE2E3 RDH12 26186194 0004 HT UBE2E3 FSD1 26186194 0004 HT BRCA1 UBE2E3 21965653,19712108,19712108,19712108 0096,0018,0114,0096 LC MDM2 UBE2E3 24980433,21965653 0096,0096 LC UBE2E3 RNF25 26475854,24901938,24901938 0096,0415,0096 LC HEL112 UBE2E3 19549727 0018 HT TRIM38 UBE2E3 21143188 0018 LC CHUK UBE2E3 9409737 0018 LC MID1 UBE2E3 19549727,21143188,25416956,25416956,25416956,25416956,19549727 0397,0018,1112,0397,0018,1356,0018 HT,LC RNF13 UBE2E3 19690564,19690564 0397,0018 HT RNF8 UBE2E3 11322894,11322894 0096,0018 LC UFL1 UBE2E3 19690564 0397 HT UBOX5 UBE2E3 11274149 0018 LC TRIM37 UBE2E3 21143188 0018 LC UBR5 UBE2E3 19549727 0018 HT ARIH2 UBE2E3 19549727,19549727 0397,0018 HT CNOT4 UBE2E3 19690564,15001359,11823428,19690564 0397,0018,0018,0018 HT,LC LSM8 UBE2E3 19549727 0018 HT UBB UBE2E3 19549727 0018 HT UBC UBE2E3 22496338,19549727 0415,0018 LC,HT TRIM27 UBE2E3 21143188 0018 LC UBA1 UBE2E3 22069333 0415 LC NFKBIA UBE2E3 9734360,9409737,10582246 0018,0018,0018 LC TGFBR1 UBE2E3 15761153 0019 HT BRCA1 UBE2E3 19712108,17873885,19712108,19712108 0018,0018,0114,0096 LC HTT UBE2E3 23275563,23275563 1112,0018 HT RPL14 UBE2E3 19549727 0018 HT ATXN1 UBE2E3 16713569 0018 HT MAGOH UBE2E3 19549727 0018 HT UFM1 UBE2E3 19690564 0018 HT EEF1A1 UBE2E3 19549727 0018 HT RNF4 UBE2E3 19549727,19549727 0397,0018 HT ACVR1 UBE2E3 15761153 0019 HT RING1 UBE2E3 19549727,19549727 0397,0018 HT TRIM32 UBE2E3 21143188 0018 LC MKRN3 UBE2E3 19549727,19549727 0397,0018 HT TARDBP UBE2E3 24825905,24825905 0018,0004 LC CUL1 UBE2E3 17452440 0415 LC CUL4A UBE2E3 17452440 0415 LC UBAP2L UBE2E3 19549727 0018 HT RNF220 UBE2E3 19549727 0018 HT RNF43 UBE2E3 19690564,19690564 0397,0018 HT Q6GX22 UBE2E3 21143188 0018 LC RFWD3 UBE2E3 19549727,19549727 0397,0018 HT RNF111 UBE2E3 19690564,19549727,19549727,19690564 0397,0397,0018,0018 HT RNF165 UBE2E3 19690564,19690564 0397,0018 HT DET1 UBE2E3 17452440,17452440 0004,0415 LC HUWE1 UBE2E3 19549727 0018 HT CADPS2 UBE2E3 19690564,19690564 0397,0018 HT RNF130 UBE2E3 19690564,19690564 0397,0018 HT TRIM50 UBE2E3 21143188 0018 LC DZIP3 UBE2E3 19549727,19549727 0397,0018 HT SIAH1 UBE2E3 11389839 0018 LC ARRDC1 UBE2E3 19549727 0018 HT RNF10 UBE2E3 19549727,19549727 0397,0018 HT DTX3 UBE2E3 19549727,19549727 0397,0018 HT ZNRF1 UBE2E3 19549727,19549727 0397,0018 HT ANKRD20A12P UBE2E3 19549727 0018 HT DTX3L UBE2E3 19549727,19549727 0397,0018 HT CEP192 UBE2E3 19549727 0018 HT ZNRF4 UBE2E3 19690564,19690564 0397,0018 HT UBE2E3 UBE2E3 20061386,20484052 0415,0415 LC UBE2E3 MUL1 25224329,19690564,19690564 0018,0397,0018 LC,HT UBE2E3 RNF166 19549727,19549727 0397,0018 HT UBE2E3 RNF25 19549727,19690564,19690564,19549727,24901938,24901938 0397,0397,0018,0018,0415,0096 HT,LC UBE2E3 CHFR 19549727,19549727 0397,0018 HT UBE2E3 RMND5B 19690564,19690564 0397,0018 HT UBE2E3 RNF185 19549727,25416956,25416956,25416956,25416956,19549727 0397,1112,0397,0018,1356,0018 HT UBE2E3 RNF2 19549727,19549727 0397,0018 HT UBE2E3 ARID3A 15017387,15017387 0004,0018 LC UBE2E3 RNF5 19549727,14667819,25416956,25416956,25416956,25416956,15545318,19549727 0397,0018,1112,0397,0018,1356,0018,0018 HT,LC UBE2E3 Q9BSK3 9920803 0415 LC UBE2E3 DDA1 17452440,17452440 0004,0401 LC UBE2E3 TRIM2 19549727,19549727 0397,0018 HT UBE2E3 RNF167 19690564,19690564,23414517 0397,0018,0399 HT UBE2E3 TRIM45 21143188 0018 LC UBE2E3 TRIM39 19549727,25416956,25416956,25416956,25416956,19549727 0397,1112,0397,0018,1356,0018 HT UBE2E3 RNF181 19690564,19690564 0397,0018 HT UBE2E3 RNF14 11322894,19549727,19549727,11322894 0096,0397,0018,0018 LC,HT UBE2E3 IPO11 11809816,15545318,15545318 0018,0096,0018 LC UBE2E3 HERC5 19549727 0018 HT UBE2E3 MID2 21143188 0018 LC UBE2E3 RNF150 19690564,19690564 0397,0018 HT UBE2E3 RNF11 19549727,19549727 0397,0018 HT UBE2E3 RNF115 19690564,19690564 0397,0018 HT UBE2E3 RNF114 19549727,19549727 0397,0018 HT UBE2E3 AUP1 19549727 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q969T4 Q59EL1 UBE2E3 Q59EL1 0.126 19690564 Q969T4 Q5VTB9 UBE2E3 RNF220 0.183 19549727 Q969T4 O43597 UBE2E3 SPRY2 0.126 26186194 Q9H8W5 Q969T4 TRIM45 UBE2E3 0.183 21143188 Q9HBD1 Q969T4 RC3H2 UBE2E3 0.309 26489670 Q969T4 Q8N9I9 UBE2E3 DTX3 0.376 19549727 Q9HCM9 Q969T4 TRIM39 UBE2E3 0.702 19549727,25416956,unassigned1304 Q969T4 O60907 UBE2E3 TBL1X 0.21 18202150 Q969T4 Q8TCJ0 UBE2E3 FBXO25 0.126 26186194 Q9NX47 Q969T4 MARCH5 UBE2E3 0.309 16936636 Q969T4 Q8TEP8 UBE2E3 CEP192 0.183 19549727 Q969T4 Q8IUQ4 UBE2E3 SIAH1 0.309 11389839 Q9NZJ0 Q969T4 DTL UBE2E3 0.21 21628527 Q9Y4L5 Q969T4 RNF115 UBE2E3 0.454 19690564,unassigned1304 Q9Y3C5 Q969T4 RNF11 UBE2E3 0.376 19549727 Q969T4 Q6ZNA4 UBE2E3 RNF111 0.554 19690564,19549727 Q969T4 Q6ZUS5 UBE2E3 CCDC121 0.126 26186194 Q969T4 Q86UW7 UBE2E3 CADPS2 0.376 19690564 Q969T4 Q86Y13 UBE2E3 DZIP3 0.376 19549727 Q969T4 O95376 UBE2E3 ARIH2 0.376 19549727 Q9NXJ5 Q969T4 PGPEP1 UBE2E3 0.236 unassigned1304 Q9H6Y7 Q969T4 RNF167 UBE2E3 0.454 19690564,23414517 Q9UBS8 Q969T4 RNF14 UBE2E3 0.659 19549727,11322894 Q9NRD5 Q969T4 PICK1 UBE2E3 0.236 unassigned1304 Q969T4 P78317 UBE2E3 RNF4 0.569 19549727,25960396 Q969T4 O95628 UBE2E3 CNOT4 0.702 19690564,15001359,11823428 Q969T4 Q8TDB6 UBE2E3 DTX3L 0.286 19549727 Q969T4 Q6ZSG1 UBE2E3 RNF165 0.286 19690564 Q969T4 Q16236 UBE2E3 NFE2L2 0.454 20484052 Q969T4 Q15038 UBE2E3 DAZAP2 0.236 unassigned1304 Q969T4 Q68DV7 UBE2E3 RNF43 0.286 19690564 Q969T4 Q6PCD5 UBE2E3 RFWD3 0.286 19549727 Q969T4 Q8ND25 UBE2E3 ZNRF1 0.286 19549727 Q969T4 Q8N5U6 UBE2E3 RNF10 0.286 19549727 Q96B67 Q969T4 ARRDC3 UBE2E3 0.236 unassigned1304 Q969T4 Q8WWF5 UBE2E3 ZNRF4 0.286 19690564 Q96A37 Q969T4 RNF166 UBE2E3 0.286 19549727 Q969V5 Q969T4 MUL1 UBE2E3 0.569 19690564,25224329 Q9C040 Q969T4 TRIM2 UBE2E3 0.286 19549727 Q9BVG3 Q969T4 TRIM62 UBE2E3 0.236 unassigned1304 Q9Y508 Q969T4 RNF114 UBE2E3 0.286 19549727 Q9BV68 Q969T4 RNF126 UBE2E3 0.236 unassigned1304 Q99856 Q969T4 ARID3A UBE2E3 0.454 15017387 Q969T4 Q00987 UBE2E3 MDM2 0.436 24980433,21965653 Q969T4 P22314 UBE2E3 UBA1 0.523 22069333,17597759 Q969T4 Q13148 UBE2E3 TARDBP 0.454 24825905 Q96BH1 Q969T4 RNF25 UBE2E3 0.853 19690564,19549727,24901938,26475854 Q96GF1 Q969T4 RNF185 UBE2E3 0.74 19549727,25416956,unassigned1304 Q96EP1 Q969T4 CHFR UBE2E3 0.454 19549727,unassigned1304 Q99942 Q969T4 RNF5 UBE2E3 0.853 14667819,25416956,unassigned1304,15545318,19549727 Q96FW1 Q969T4 OTUB1 UBE2E3 0.416 26752685,unassigned1304 Q969T4 O15344 UBE2E3 MID1 0.801 25416956,unassigned1304,21143188,19549727 Q969T4 P38398 UBE2E3 BRCA1 0.843 19712108,17873885,21965653 Q969T4 Q969F2 UBE2E3 NKD2 0.126 26186194 Q969T4 A8CGI2 UBE2E3 UBC 0.332 19549727 Q969T4 B2RDW1 UBE2E3 RPS27A 0.332 19549727 Q969T4 O43567 UBE2E3 RNF13 0.286 19690564 Q969T4 O43791 UBE2E3 SPOP 0.309 19256485 Q969T4 O76064 UBE2E3 RNF8 0.523 11322894 Q969T4 O94874 UBE2E3 UFL1 0.126 19690564 Q969T4 O94972 UBE2E3 TRIM37 0.332 21143188 Q969T4 O95071 UBE2E3 UBR5 0.183 19549727 Q969T4 O95199 UBE2E3 RCBTB2 0.309 19256485 Q969T4 O95777 UBE2E3 LSM8 0.183 19549727 Q969T4 P0CG48 UBE2E3 UBC 0.309 22496338 Q969T4 P14373 UBE2E3 TRIM27 0.332 21143188 Q969T4 P42858 UBE2E3 HTT 0.286 23275563 Q969T4 P46060 UBE2E3 RANGAP1 0.309 9920803 Q969T4 P50914 UBE2E3 RPL14 0.183 19549727 Q969T4 P54253 UBE2E3 ATXN1 0.332 16713569 Q969T4 P61326 UBE2E3 MAGOH 0.183 19549727 Q969T4 P61960 UBE2E3 UFM1 0.183 19690564 Q969T4 P68104 UBE2E3 EEF1A1 0.332 19549727 Q969T4 Q06587 UBE2E3 RING1 0.286 19549727 Q969T4 Q13049 UBE2E3 TRIM32 0.332 21143188 Q969T4 Q13616 UBE2E3 CUL1 0.309 19256485 Q969T4 Q13618 UBE2E3 CUL3 0.309 19256485 Q969T4 Q13619 UBE2E3 CUL4A 0.309 19256485 Q969T4 Q14157 UBE2E3 UBAP2L 0.332 19549727 Q969T4 Q16531 UBE2E3 DDB1 0.21 17452440 Q969T4 Q5U5U6 UBE2E3 UBB 0.183 19549727 Q969T4 Q7L5Y6 UBE2E3 DET1 0.376 17452440 Q969T4 Q7Z6Z7 UBE2E3 HUWE1 0.332 19549727 Q969T4 Q86XS8 UBE2E3 RNF130 0.286 19690564 Q969T4 Q86XT4 UBE2E3 TRIM50 0.49 unassigned1304,21143188 Q969T4 Q8N5I2 UBE2E3 ARRDC1 0.332 19549727 Q969T4 Q8NDN9 UBE2E3 RCBTB1 0.309 19256485 Q969T4 Q8NF67 UBE2E3 Q8NF67 0.183 19549727 Q969T4 Q969T4 UBE2E3 UBE2E3 0.332 20484052 Q96G75 Q969T4 RMND5B UBE2E3 0.286 19690564 Q99496 Q969T4 RNF2 UBE2E3 0.454 19549727,unassigned1304 Q99PZ6 Q969T4 OSPG UBE2E3 0.21 24446487 Q9BW61 Q969T4 DDA1 UBE2E3 0.309 17452440 Q9P2K6 Q969T4 KLHL42 UBE2E3 0.309 19256485 Q9UI26 Q969T4 IPO11 UBE2E3 0.671 15545318 Q9UII4 Q969T4 HERC5 UBE2E3 0.183 19549727 Q9Y679 Q969T4 AUP1 UBE2E3 0.183 19549727 Q96J02 Q969T4 ITCH UBE2E3 0.309 22496338 Q96NR8 Q969T4 RDH12 UBE2E3 0.126 26186194 Q9BTV5 Q969T4 FSD1 UBE2E3 0.126 26186194 Q99728 Q969T4 BARD1 UBE2E3 0.309 21965653 Q9BZK7 Q969T4 TBL1XR1 UBE2E3 0.21 18202150 Q9P0P0 Q969T4 RNF181 UBE2E3 0.376 19690564 Q9UJV3 Q969T4 MID2 UBE2E3 0.49 unassigned1304,21143188 Q9ULK6 Q969T4 RNF150 UBE2E3 0.376 19690564 Q969T4 P34909 UBE2E3 MOT2 0.309 11823428 Q969T4 P41161 UBE2E3 ETV5 0.126 26186194 Q969T4 Q13064 UBE2E3 MKRN3 0.376 19549727 Q969T4 O00308 UBE2E3 WWP2 0.472 unassigned1304,22496338 Q969T4 O00635 UBE2E3 TRIM38 0.183 21143188

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PSMD11 UBE2E3 MI:0362 inference MI:0461 interaction database WWP2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database PSMD14 UBE2E3 MI:0362 inference MI:0461 interaction database PEX12 UBE2E3 MI:0362 inference MI:0461 interaction database TRIM38 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database MID1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database DAPK3 UBE2E3 MI:0362 inference MI:0461 interaction database RNF13 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database SPRY2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database SPOP UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database PEX10 UBE2E3 MI:0362 inference MI:0461 interaction database TBL1X UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database PTCD1 UBE2E3 MI:0362 inference MI:0461 interaction database RNF8 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UFL1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database TRIM37 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UBR5 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UBE4B UBE2E3 MI:0362 inference MI:0461 interaction database RCBTB2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database ARIH2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CNOT4 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database LSM8 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CHEK2 UBE2E3 MI:0362 inference MI:0461 interaction database UBC UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HSPA1A UBE2E3 MI:0362 inference MI:0461 interaction database HSPA1B UBE2E3 MI:0362 inference MI:0461 interaction database DLAT UBE2E3 MI:0362 inference MI:0461 interaction database HSPA8 UBE2E3 MI:0362 inference MI:0461 interaction database TRIM27 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UQCRB UBE2E3 MI:0362 inference MI:0461 interaction database HSPA6 UBE2E3 MI:0362 inference MI:0461 interaction database PSMC3 UBE2E3 MI:0362 inference MI:0461 interaction database TRIM21 UBE2E3 MI:0362 inference MI:0461 interaction database BTF3 UBE2E3 MI:0362 inference MI:0461 interaction database TNFAIP3 UBE2E3 MI:0362 inference MI:0461 interaction database UBA1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CBL UBE2E3 MI:0362 inference MI:0461 interaction database NFKBIA UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database PSMB8 UBE2E3 MI:0362 inference MI:0461 interaction database PSMB5 UBE2E3 MI:0362 inference MI:0461 interaction database HSPA1L UBE2E3 MI:0362 inference MI:0461 interaction database TGFBR1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database BRCA1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database ETV5 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HTT UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RANGAP1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RPS5 UBE2E3 MI:0362 inference MI:0461 interaction database NEDD4 UBE2E3 MI:0362 inference MI:0461 interaction database UBE2A UBE2E3 MI:0362 inference MI:0461 interaction database PSMB2 UBE2E3 MI:0362 inference MI:0461 interaction database PEX5 UBE2E3 MI:0362 inference MI:0461 interaction database RPL14 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 UBE2E3 MI:0362 inference MI:0461 interaction database MNAT1 UBE2E3 MI:0362 inference MI:0461 interaction database UBE2E1 UBE2E3 MI:0362 inference MI:0461 interaction database CLTCL1 UBE2E3 MI:0362 inference MI:0461 interaction database ATXN1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HSPA2 UBE2E3 MI:0362 inference MI:0461 interaction database CSE1L UBE2E3 MI:0362 inference MI:0461 interaction database UBE2N UBE2E3 MI:0362 inference MI:0461 interaction database MAGOH UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UFM1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UBE2H UBE2E3 MI:0362 inference MI:0461 interaction database UBE2D2 UBE2E3 MI:0362 inference MI:0461 interaction database RBX1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database DYNLT1 UBE2E3 MI:0362 inference MI:0461 interaction database EEF1A1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A UBE2E3 MI:0362 inference MI:0461 interaction database RNF4 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database H3F3A UBE2E3 MI:0362 inference MI:0461 interaction database CLTC UBE2E3 MI:0362 inference MI:0461 interaction database MDM2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database GALK2 UBE2E3 MI:0362 inference MI:0461 interaction database ACVR1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database ICA1 UBE2E3 MI:0362 inference MI:0461 interaction database RING1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF2 UBE2E3 MI:0362 inference MI:0461 interaction database TRIM32 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database MKRN3 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database TARDBP UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CBLB UBE2E3 MI:0362 inference MI:0461 interaction database MAP3K1 UBE2E3 MI:0362 inference MI:0461 interaction database UBE2V1 UBE2E3 MI:0362 inference MI:0461 interaction database SNW1 UBE2E3 MI:0362 inference MI:0461 interaction database CUL1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B UBE2E3 MI:0362 inference MI:0461 interaction database GTF2H2 UBE2E3 MI:0362 inference MI:0461 interaction database UBAP2L UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database TRIP12 UBE2E3 MI:0362 inference MI:0461 interaction database RRS1 UBE2E3 MI:0362 inference MI:0461 interaction database UBE3C UBE2E3 MI:0362 inference MI:0461 interaction database NFE2L2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database DDB1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HIST3H3 UBE2E3 MI:0362 inference MI:0461 interaction database TRIM71 UBE2E3 MI:0362 inference MI:0461 interaction database GLYR1 UBE2E3 MI:0362 inference MI:0461 interaction database YIF1B UBE2E3 MI:0362 inference MI:0461 interaction database HERC4 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RNF220 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RNF43 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database H3F3C UBE2E3 MI:0362 inference MI:0461 interaction database GTF2H2C UBE2E3 MI:0362 inference MI:0461 interaction database RFWD3 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 UBE2E3 MI:0362 inference MI:0461 interaction database RNF111 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RNF165 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CCDC121 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H3A UBE2E3 MI:0362 inference MI:0461 interaction database COPS6 UBE2E3 MI:0362 inference MI:0461 interaction 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MI:0045 experimental interaction detection MI:0461 interaction database ICA1L UBE2E3 MI:0362 inference MI:0461 interaction database RCBTB1 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database ANKRD20A12P UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 UBE2E3 MI:0362 inference MI:0461 interaction database FBXO25 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database DTX3L UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CEP192 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database CHTF18 UBE2E3 MI:0362 inference MI:0461 interaction database ZNRF4 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RAD54L UBE2E3 MI:0362 inference MI:0461 interaction database COPS5 UBE2E3 MI:0362 inference MI:0461 interaction database NKD2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 MUL1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF166 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF25 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF31 MI:0362 inference MI:0461 interaction database UBE2E3 CHFR MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 OTUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RMND5B MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF185 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 ITCH MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 PDLIM2 MI:0362 inference MI:0461 interaction database UBE2E3 BTF3L4 MI:0362 inference MI:0461 interaction database UBE2E3 UBE2E2 MI:0362 inference MI:0461 interaction database UBE2E3 RDH12 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 NEDD4L MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 COPS8 MI:0362 inference MI:0461 interaction database UBE2E3 BARD1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 ARID3A MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 NEURL2 MI:0362 inference MI:0461 interaction database UBE2E3 COPS4 MI:0362 inference MI:0461 interaction database UBE2E3 FSD1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 DDA1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TBL1XR1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRIM2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 NACA2 MI:0362 inference MI:0461 interaction database UBE2E3 RNF41 MI:0362 inference MI:0461 interaction database UBE2E3 RNF167 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RC3H2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRIM39 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 MARCH5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 ANAPC11 MI:0362 inference MI:0461 interaction database UBE2E3 RNF181 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 KLHL42 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF14 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 IPO11 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 HERC5 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 MID2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 FZR1 MI:0362 inference MI:0461 interaction database UBE2E3 STUB1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 COPS3 MI:0362 inference MI:0461 interaction database UBE2E3 UBE2D4 MI:0362 inference MI:0461 interaction database UBE2E3 RNF11 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRAF6 MI:0362 inference MI:0461 interaction database UBE2E3 RNF115 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 ARIH1 MI:0362 inference MI:0461 interaction database UBE2E3 RNF114 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRIM17 MI:0362 inference MI:0461 interaction database UBE2E3 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database