Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 3 4355141 4355141 + Missense_Mutation SNP C C T TCGA-OR-A5J4-01A-11D-A29I-10 TCGA-OR-A5J4-10A-01D-A29L-10 g.chr3:4355141C>T c.716C>T c.(715-717)tCa>tTa p.S239L BLCA 3 4345157 4345157 + Nonsense_Mutation SNP G G T TCGA-E5-A4TZ-01A-11D-A31L-08 TCGA-E5-A4TZ-10B-01D-A31J-08 g.chr3:4345157G>T c.103G>T c.(103-105)Gaa>Taa p.E35* BLCA 3 4354714 4354714 + Missense_Mutation SNP G G A TCGA-E7-A7DV-01A-11D-A339-08 TCGA-E7-A7DV-10A-01D-A339-08 g.chr3:4354714G>A c.289G>A c.(289-291)Gat>Aat p.D97N BRCA 3 4354769 4354769 + Frame_Shift_Del DEL T T - TCGA-AN-A0AK-01A-21W-A019-09 TCGA-AN-A0AK-10A-01W-A021-09 g.chr3:4354769delT c.344delT c.(343-345)gttfs p.V115fs BRCA 3 4355372 4355372 + Missense_Mutation SNP G G C TCGA-A8-A09N-01A-11W-A019-09 TCGA-A8-A09N-10A-01W-A021-09 g.chr3:4355372G>C c.947G>C c.(946-948)gGa>gCa p.G316A CESC 3 4345118 4345118 + Missense_Mutation SNP G G A TCGA-DG-A2KH-01A-21D-A22X-09 TCGA-DG-A2KH-10A-01D-A22X-09 g.chr3:4345118G>A c.64G>A c.(64-66)Gag>Aag p.E22K CESC 3 4354762 4354762 + Missense_Mutation SNP G G A TCGA-JW-A5VL-01A-11D-A28B-09 TCGA-JW-A5VL-10A-01D-A28E-09 g.chr3:4354762G>A c.337G>A c.(337-339)Gag>Aag p.E113K CESC 3 4358097 4358097 + Missense_Mutation SNP C C T TCGA-Q1-A73S-01A-11D-A33O-09 TCGA-Q1-A73S-10B-01D-A33O-09 g.chr3:4358097C>T c.1222C>T c.(1222-1224)Cgg>Tgg p.R408W CESC 3 4358139 4358139 + Missense_Mutation SNP G G A TCGA-EK-A2R8-01A-21D-A18J-09 TCGA-EK-A2R8-10A-01D-A18J-09 g.chr3:4358139G>A c.1264G>A c.(1264-1266)Gaa>Aaa p.E422K CESC 3 4358681 4358681 + Missense_Mutation SNP G G C TCGA-DG-A2KL-01A-11D-A17W-09 TCGA-DG-A2KL-10A-01D-A17W-09 g.chr3:4358681G>C c.1806G>C c.(1804-1806)ttG>ttC p.L602F COAD 3 4345150 4345150 + Silent SNP C C T TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr3:4345150C>T c.96C>T c.(94-96)tgC>tgT p.C32C COAD 3 4354769 4354769 + Frame_Shift_Del DEL T T - TCGA-CM-5861-01A-01D-1650-10 TCGA-CM-5861-10A-01D-1650-10 g.chr3:4354769delT c.344delT c.(343-345)gttfs p.V115fs COAD 3 4354844 4354844 + Missense_Mutation SNP A A G TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr3:4354844A>G c.419A>G c.(418-420)cAc>cGc p.H140R COAD 3 4354867 4354867 + Frame_Shift_Del DEL A A - TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr3:4354867delA c.442delA c.(442-444)aaafs p.K149fs COAD 3 4354875 4354875 + Silent SNP C C T TCGA-D5-6928-01A-11D-1924-10 TCGA-D5-6928-10A-01D-1924-10 g.chr3:4354875C>T c.450C>T c.(448-450)ggC>ggT p.G150G COAD 3 4354905 4354905 + Silent SNP G G A TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr3:4354905G>A c.480G>A c.(478-480)ccG>ccA p.P160P COAD 3 4358834 4358834 + Silent SNP C C T TCGA-AA-3977-01A-01W-0995-10 TCGA-AA-3977-10A-01W-0999-10 g.chr3:4358834C>T c.1959C>T c.(1957-1959)gtC>gtT p.V653V COADREAD 3 4345150 4345150 + Silent SNP C C T TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr3:4345150C>T c.96C>T c.(94-96)tgC>tgT p.C32C COADREAD 3 4354769 4354769 + Frame_Shift_Del DEL T T - TCGA-CM-5861-01A-01D-1650-10 TCGA-CM-5861-10A-01D-1650-10 g.chr3:4354769delT c.344delT c.(343-345)gttfs p.V115fs COADREAD 3 4354844 4354844 + Missense_Mutation SNP A A G TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr3:4354844A>G c.419A>G c.(418-420)cAc>cGc p.H140R COADREAD 3 4354867 4354867 + Frame_Shift_Del DEL A A - TCGA-AA-3815-01A-01W-0995-10 TCGA-AA-3815-10A-01W-0995-10 g.chr3:4354867delA c.442delA c.(442-444)aaafs p.K149fs COADREAD 3 4354875 4354875 + Silent SNP C C T TCGA-D5-6928-01A-11D-1924-10 TCGA-D5-6928-10A-01D-1924-10 g.chr3:4354875C>T c.450C>T c.(448-450)ggC>ggT p.G150G COADREAD 3 4354905 4354905 + Silent SNP G G A TCGA-A6-5661-01A-01D-1650-10 TCGA-A6-5661-10A-01D-1650-10 g.chr3:4354905G>A c.480G>A c.(478-480)ccG>ccA p.P160P COADREAD 3 4355431 4355431 + Nonsense_Mutation SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr3:4355431C>T c.1006C>T c.(1006-1008)Cga>Tga p.R336* COADREAD 3 4358834 4358834 + Silent SNP C C T TCGA-AA-3977-01A-01W-0995-10 TCGA-AA-3977-10A-01W-0999-10 g.chr3:4358834C>T c.1959C>T c.(1957-1959)gtC>gtT p.V653V DLBC 3 4354652 4354652 + Missense_Mutation SNP T T C TCGA-GS-A9TX-01A-11D-A382-10 TCGA-GS-A9TX-10A-01D-A385-10 g.chr3:4354652T>C c.227T>C c.(226-228)aTt>aCt p.I76T DLBC 3 4358476 4358476 + Missense_Mutation SNP C C T TCGA-G8-6326-01A-11D-2210-10 TCGA-G8-6326-10A-01D-2210-10 g.chr3:4358476C>T c.1601C>T c.(1600-1602)aCt>aTt p.T534I ESCA 3 4357930 4357930 + Missense_Mutation SNP G G T TCGA-V5-AASV-01A-11D-A387-09 TCGA-V5-AASV-10A-01D-A38A-09 g.chr3:4357930G>T c.1055G>T c.(1054-1056)cGa>cTa p.R352L GBMLGG 3 4354791 4354791 + Silent SNP C C T TCGA-E1-5307-01A-01D-1893-08 TCGA-E1-5307-10A-01D-1893-08 g.chr3:4354791C>T c.366C>T c.(364-366)tgC>tgT p.C122C GBMLGG 3 4355172 4355172 + Silent SNP C C G TCGA-QH-A65S-01A-11D-A29Q-08 TCGA-QH-A65S-10A-01D-A29Q-08 g.chr3:4355172C>G c.747C>G c.(745-747)gcC>gcG p.A249A GBMLGG 3 4355208 4355208 + Missense_Mutation SNP T T G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr3:4355208T>G c.783T>G c.(781-783)gaT>gaG p.D261E GBMLGG 3 4355408 4355409 + Frame_Shift_Ins INS - - T TCGA-QH-A65S-01A-11D-A29Q-08 TCGA-QH-A65S-10A-01D-A29Q-08 g.chr3:4355408_4355409insT c.983_984insT c.(982-987)ccttctfs p.S329fs GBMLGG 3 4358185 4358185 + Missense_Mutation SNP A A G TCGA-FG-8186-01A-11D-2253-08 TCGA-FG-8186-10A-01D-2253-08 g.chr3:4358185A>G c.1310A>G c.(1309-1311)aAt>aGt p.N437S HNSC 3 4355021 4355021 + Missense_Mutation SNP A A G TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr3:4355021A>G c.596A>G c.(595-597)cAt>cGt p.H199R HNSC 3 4355272 4355272 + Missense_Mutation SNP C C G TCGA-CR-7379-01A-11D-2012-08 TCGA-CR-7379-10A-01D-2013-08 g.chr3:4355272C>G c.847C>G c.(847-849)Cta>Gta p.L283V KIPAN 3 4355062 4355062 + Missense_Mutation SNP A A G TCGA-A3-3311-01A-01D-0966-08 TCGA-A3-3311-11A-01D-0966-08 g.chr3:4355062A>G c.637A>G c.(637-639)Act>Gct p.T213A KIPAN 3 4355443 4355443 + Missense_Mutation SNP G G C TCGA-5P-A9JW-01A-11D-A42J-10 TCGA-5P-A9JW-10A-01D-A42M-10 g.chr3:4355443G>C c.1018G>C c.(1018-1020)Gag>Cag p.E340Q KIRC 3 4355062 4355062 + Missense_Mutation SNP A A G TCGA-A3-3311-01A-01D-0966-08 TCGA-A3-3311-11A-01D-0966-08 g.chr3:4355062A>G c.637A>G c.(637-639)Act>Gct p.T213A KIRP 3 4355443 4355443 + Missense_Mutation SNP G G C TCGA-5P-A9JW-01A-11D-A42J-10 TCGA-5P-A9JW-10A-01D-A42M-10 g.chr3:4355443G>C c.1018G>C c.(1018-1020)Gag>Cag p.E340Q LGG 3 4354791 4354791 + Silent SNP C C T TCGA-E1-5307-01A-01D-1893-08 TCGA-E1-5307-10A-01D-1893-08 g.chr3:4354791C>T c.366C>T c.(364-366)tgC>tgT p.C122C LGG 3 4355172 4355172 + Silent SNP C C G TCGA-QH-A65S-01A-11D-A29Q-08 TCGA-QH-A65S-10A-01D-A29Q-08 g.chr3:4355172C>G c.747C>G c.(745-747)gcC>gcG p.A249A LGG 3 4355208 4355208 + Missense_Mutation SNP T T G TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr3:4355208T>G c.783T>G c.(781-783)gaT>gaG p.D261E LGG 3 4355408 4355409 + Frame_Shift_Ins INS - - T TCGA-QH-A65S-01A-11D-A29Q-08 TCGA-QH-A65S-10A-01D-A29Q-08 g.chr3:4355408_4355409insT c.983_984insT c.(982-987)ccttctfs p.S329fs LGG 3 4358185 4358185 + Missense_Mutation SNP A A G TCGA-FG-8186-01A-11D-2253-08 TCGA-FG-8186-10A-01D-2253-08 g.chr3:4358185A>G c.1310A>G c.(1309-1311)aAt>aGt p.N437S LIHC 3 4354838 4354838 + Missense_Mutation SNP A A C TCGA-DD-AADS-01A-11D-A40R-10 TCGA-DD-AADS-10A-01D-A40U-10 g.chr3:4354838A>C c.413A>C c.(412-414)cAg>cCg p.Q138P LIHC 3 4354904 4354904 + Missense_Mutation SNP C C T TCGA-DD-AAE6-01A-11D-A40R-10 TCGA-DD-AAE6-10A-01D-A40U-10 g.chr3:4354904C>T c.479C>T c.(478-480)cCg>cTg p.P160L LIHC 3 4358293 4358293 + Missense_Mutation SNP T T G TCGA-DD-AADE-01A-11D-A40R-10 TCGA-DD-AADE-10A-01D-A40U-10 g.chr3:4358293T>G c.1418T>G c.(1417-1419)tTt>tGt p.F473C LIHC 3 4358307 4358307 + Missense_Mutation SNP T T G TCGA-DD-AADE-01A-11D-A40R-10 TCGA-DD-AADE-10A-01D-A40U-10 g.chr3:4358307T>G c.1432T>G c.(1432-1434)Tct>Gct p.S478A LUAD 3 4354588 4354588 + Missense_Mutation SNP C C A TCGA-44-8119-01A-11D-2238-08 TCGA-44-8119-10A-01D-2238-08 g.chr3:4354588C>A c.163C>A c.(163-165)Cct>Act p.P55T LUAD 3 4354885 4354885 + Missense_Mutation SNP C C T TCGA-86-A4JF-01A-11D-A24P-08 TCGA-86-A4JF-10A-01D-A24P-08 g.chr3:4354885C>T c.460C>T c.(460-462)Cgt>Tgt p.R154C LUAD 3 4355245 4355245 + Missense_Mutation SNP G G A TCGA-91-8499-01A-11D-2393-08 TCGA-91-8499-10A-01D-2393-08 g.chr3:4355245G>A c.820G>A c.(820-822)Gac>Aac p.D274N LUAD 3 4355405 4355405 + Missense_Mutation SNP C C A TCGA-78-8640-01A-11D-2393-08 TCGA-78-8640-11A-01D-2393-08 g.chr3:4355405C>A c.980C>A c.(979-981)gCc>gAc p.A327D OV 3 4354990 4354990 + Missense_Mutation SNP G G A TCGA-13-1495-01A-01W-0545-08 TCGA-13-1495-10A-01D-0472-08 g.chr3:4354990G>A c.565G>A c.(565-567)Gac>Aac p.D189N PRAD 3 4354786 4354786 + Missense_Mutation SNP C C A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr3:4354786C>A c.361C>A c.(361-363)Ctg>Atg p.L121M READ 3 4355431 4355431 + Nonsense_Mutation SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr3:4355431C>T c.1006C>T c.(1006-1008)Cga>Tga p.R336* SKCM 3 4345113 4345113 + Missense_Mutation SNP A A C TCGA-D9-A6EC-06A-11D-A30X-08 TCGA-D9-A6EC-10A-01D-A30X-08 g.chr3:4345113A>C c.59A>C c.(58-60)aAg>aCg p.K20T SKCM 3 4354724 4354724 + Missense_Mutation SNP C C T TCGA-ER-A3PL-06A-11D-A23B-08 TCGA-ER-A3PL-10A-01D-A23B-08 g.chr3:4354724C>T c.299C>T c.(298-300)tCa>tTa p.S100L SKCM 3 4354817 4354817 + Missense_Mutation SNP G G A TCGA-GN-A4U3-06A-11D-A32N-08 TCGA-GN-A4U3-10F-01D-A32N-08 g.chr3:4354817G>A c.392G>A c.(391-393)aGa>aAa p.R131K SKCM 3 4354988 4354988 + Missense_Mutation SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr3:4354988C>T c.563C>T c.(562-564)tCc>tTc p.S188F SKCM 3 4355387 4355387 + Missense_Mutation SNP C C T TCGA-EE-A2M6-06A-12D-A197-08 TCGA-EE-A2M6-10A-01D-A199-08 g.chr3:4355387C>T c.962C>T c.(961-963)cCc>cTc p.P321L SKCM 3 4355398 4355398 + Missense_Mutation SNP G G A TCGA-ER-A19H-06A-12D-A196-08 TCGA-ER-A19H-10A-01D-A198-08 g.chr3:4355398G>A c.973G>A c.(973-975)Ggc>Agc p.G325S SKCM 3 4355399 4355399 + Missense_Mutation SNP G G A TCGA-ER-A19H-06A-12D-A196-08 TCGA-ER-A19H-10A-01D-A198-08 g.chr3:4355399G>A c.974G>A c.(973-975)gGc>gAc p.G325D SKCM 3 4355407 4355407 + Missense_Mutation SNP C C T TCGA-EE-A2GL-06A-11D-A196-08 TCGA-EE-A2GL-10A-01D-A198-08 g.chr3:4355407C>T c.982C>T c.(982-984)Cct>Tct p.P328S

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 3 4355176 4355176 single base substitution G C downstream_gene_variant BLCA-CN 3 4355176 4355176 single base substitution G C intron_variant BLCA-CN 3 4355176 4355176 single base substitution G C missense_variant D251H 751G>C BRCA-EU 3 4340818 4340818 single base substitution T G upstream_gene_variant BRCA-EU 3 4341474 4341475 deletion of <=200bp AC - upstream_gene_variant BRCA-EU 3 4342323 4342323 single base substitution G C upstream_gene_variant BRCA-EU 3 4344368 4344368 single base substitution A G upstream_gene_variant BRCA-EU 3 4344940 4344940 single base substitution G A upstream_gene_variant BRCA-EU 3 4345676 4345676 single base substitution C T exon_variant BRCA-EU 3 4345676 4345676 single base substitution C T intron_variant BRCA-EU 3 4347581 4347581 single base substitution T C intron_variant BRCA-EU 3 4350765 4350765 single base substitution G C intron_variant BRCA-EU 3 4352379 4352379 single base substitution A G intron_variant BRCA-EU 3 4358848 4358848 single base substitution C T 3_prime_UTR_variant BRCA-EU 3 4358848 4358848 single base substitution C T downstream_gene_variant BRCA-EU 3 4358848 4358848 single base substitution C T missense_variant T519M 1556C>T BRCA-EU 3 4358848 4358848 single base substitution C T missense_variant T658M 1973C>T BRCA-EU 3 4359723 4359723 single base substitution G C downstream_gene_variant BRCA-EU 3 4360993 4360993 single base substitution C A downstream_gene_variant BRCA-EU 3 4361396 4361396 single base substitution G A downstream_gene_variant BRCA-EU 3 4361709 4361709 single base substitution G T downstream_gene_variant BRCA-EU 3 4363768 4363768 single base substitution T G downstream_gene_variant BRCA-FR 3 4341579 4341579 single base substitution G A upstream_gene_variant BRCA-FR 3 4363768 4363768 single base substitution T G downstream_gene_variant BRCA-US 3 4345766 4345766 single base substitution C T exon_variant BRCA-US 3 4345766 4345766 single base substitution C T intron_variant BRCA-US 3 4354769 4354769 deletion of <=200bp T - exon_variant BRCA-US 3 4354769 4354769 deletion of <=200bp T - frameshift_variant V115 BRCA-US 3 4354769 4354769 deletion of <=200bp T - intron_variant BRCA-US 3 4355372 4355372 single base substitution G C downstream_gene_variant BRCA-US 3 4355372 4355372 single base substitution G C exon_variant BRCA-US 3 4355372 4355372 single base substitution G C intron_variant BRCA-US 3 4355372 4355372 single base substitution G C missense_variant G177A 530G>C BRCA-US 3 4355372 4355372 single base substitution G C missense_variant G316A 947G>C BRCA-US 3 4355372 4355372 single base substitution G C missense_variant G80A 239G>C BTCA-JP 3 4354705 4354705 single base substitution G T exon_variant BTCA-JP 3 4354705 4354705 single base substitution G T intron_variant BTCA-JP 3 4354705 4354705 single base substitution G T stop_gained E94* 280G>T CESC-US 3 4345118 4345118 single base substitution G A exon_variant CESC-US 3 4345118 4345118 single base substitution G A missense_variant E22K 64G>A CESC-US 3 4345118 4345118 single base substitution G A upstream_gene_variant CESC-US 3 4354762 4354762 single base substitution G A exon_variant CESC-US 3 4354762 4354762 single base substitution G A intron_variant CESC-US 3 4354762 4354762 single base substitution G A missense_variant E113K 337G>A CESC-US 3 4358097 4358097 single base substitution C T 3_prime_UTR_variant CESC-US 3 4358097 4358097 single base substitution C T downstream_gene_variant CESC-US 3 4358097 4358097 single base substitution C T missense_variant R172W 514C>T CESC-US 3 4358097 4358097 single base substitution C T missense_variant R269W 805C>T CESC-US 3 4358097 4358097 single base substitution C T missense_variant R408W 1222C>T CESC-US 3 4358139 4358139 single base substitution G A 3_prime_UTR_variant CESC-US 3 4358139 4358139 single base substitution G A downstream_gene_variant CESC-US 3 4358139 4358139 single base substitution G A missense_variant E186K 556G>A CESC-US 3 4358139 4358139 single base substitution G A missense_variant E283K 847G>A CESC-US 3 4358139 4358139 single base substitution G A missense_variant E422K 1264G>A CESC-US 3 4358681 4358681 single base substitution G C 3_prime_UTR_variant CESC-US 3 4358681 4358681 single base substitution G C downstream_gene_variant CESC-US 3 4358681 4358681 single base substitution G C missense_variant L463F 1389G>C CESC-US 3 4358681 4358681 single base substitution G C missense_variant L602F 1806G>C COAD-US 3 4345150 4345150 single base substitution C T exon_variant COAD-US 3 4345150 4345150 single base substitution C T synonymous_variant C32C 96C>T COAD-US 3 4345150 4345150 single base substitution C T upstream_gene_variant COAD-US 3 4354697 4354697 single base substitution G A exon_variant COAD-US 3 4354697 4354697 single base substitution G A intron_variant COAD-US 3 4354697 4354697 single base substitution G A missense_variant R91H 272G>A COAD-US 3 4354769 4354769 deletion of <=200bp T - exon_variant COAD-US 3 4354769 4354769 deletion of <=200bp T - frameshift_variant V115 COAD-US 3 4354769 4354769 deletion of <=200bp T - intron_variant COAD-US 3 4354875 4354875 single base substitution C T downstream_gene_variant COAD-US 3 4354875 4354875 single base substitution C T exon_variant COAD-US 3 4354875 4354875 single base substitution C T intron_variant COAD-US 3 4354875 4354875 single base substitution C T synonymous_variant G150G 450C>T COAD-US 3 4354905 4354905 single base substitution G A downstream_gene_variant COAD-US 3 4354905 4354905 single base substitution G A exon_variant COAD-US 3 4354905 4354905 single base substitution G A intron_variant COAD-US 3 4354905 4354905 single base substitution G A synonymous_variant P160P 480G>A COAD-US 3 4358620 4358620 single base substitution G A 3_prime_UTR_variant COAD-US 3 4358620 4358620 single base substitution G A downstream_gene_variant COAD-US 3 4358620 4358620 single base substitution G A missense_variant G443D 1328G>A COAD-US 3 4358620 4358620 single base substitution G A missense_variant G582D 1745G>A COCA-CN 3 4344936 4344936 single base substitution T G upstream_gene_variant COCA-CN 3 4345387 4345387 single base substitution C T exon_variant COCA-CN 3 4345387 4345387 single base substitution C T intron_variant COCA-CN 3 4345387 4345387 single base substitution C T missense_variant P11L 32C>T COCA-CN 3 4355148 4355148 single base substitution A G downstream_gene_variant COCA-CN 3 4355148 4355148 single base substitution A G intron_variant COCA-CN 3 4355148 4355148 single base substitution A G synonymous_variant V241V 723A>G COCA-CN 3 4355357 4355357 single base substitution C T downstream_gene_variant COCA-CN 3 4355357 4355357 single base substitution C T exon_variant COCA-CN 3 4355357 4355357 single base substitution C T intron_variant COCA-CN 3 4355357 4355357 single base substitution C T missense_variant S172L 515C>T COCA-CN 3 4355357 4355357 single base substitution C T missense_variant S311L 932C>T COCA-CN 3 4355357 4355357 single base substitution C T missense_variant S75L 224C>T COCA-CN 3 4358286 4358286 single base substitution C T 3_prime_UTR_variant COCA-CN 3 4358286 4358286 single base substitution C T downstream_gene_variant COCA-CN 3 4358286 4358286 single base substitution C T missense_variant R332C 994C>T COCA-CN 3 4358286 4358286 single base substitution C T missense_variant R471C 1411C>T EOPC-DE 3 4344057 4344057 single base substitution T C upstream_gene_variant EOPC-DE 3 4354896 4354896 single base substitution A G downstream_gene_variant EOPC-DE 3 4354896 4354896 single base substitution A G exon_variant EOPC-DE 3 4354896 4354896 single base substitution A G intron_variant EOPC-DE 3 4354896 4354896 single base substitution A G synonymous_variant E157E 471A>G ESAD-UK 3 4341241 4341241 single base substitution T G upstream_gene_variant ESAD-UK 3 4342430 4342430 single base substitution G A upstream_gene_variant ESAD-UK 3 4343048 4343048 single base substitution C T upstream_gene_variant ESAD-UK 3 4343085 4343085 single base substitution A C upstream_gene_variant ESAD-UK 3 4343759 4343759 single base substitution C G upstream_gene_variant ESAD-UK 3 4343960 4343960 single base substitution A T upstream_gene_variant ESAD-UK 3 4344971 4344971 single base substitution G A upstream_gene_variant ESAD-UK 3 4345265 4345265 single base substitution C G intron_variant ESAD-UK 3 4345265 4345265 single base substitution C G upstream_gene_variant ESAD-UK 3 4347230 4347230 single base substitution T A intron_variant ESAD-UK 3 4349913 4349913 single base substitution G A intron_variant ESAD-UK 3 4349945 4349945 single base substitution C T intron_variant ESAD-UK 3 4355567 4355567 single base substitution T A 3_prime_UTR_variant ESAD-UK 3 4355567 4355567 single base substitution T A downstream_gene_variant ESAD-UK 3 4355567 4355567 single base substitution T A intron_variant ESAD-UK 3 4357369 4357369 single base substitution A G downstream_gene_variant ESAD-UK 3 4357369 4357369 single base substitution A G intron_variant ESAD-UK 3 4357516 4357516 single base substitution A G downstream_gene_variant ESAD-UK 3 4357516 4357516 single base substitution A G intron_variant ESAD-UK 3 4358832 4358832 single base substitution G A 3_prime_UTR_variant ESAD-UK 3 4358832 4358832 single base substitution G A downstream_gene_variant ESAD-UK 3 4358832 4358832 single base substitution G A missense_variant V514I 1540G>A ESAD-UK 3 4358832 4358832 single base substitution G A missense_variant V653I 1957G>A ESAD-UK 3 4358849 4358849 single base substitution G A 3_prime_UTR_variant ESAD-UK 3 4358849 4358849 single base substitution G A downstream_gene_variant ESAD-UK 3 4358849 4358849 single base substitution G A synonymous_variant T519T 1557G>A ESAD-UK 3 4358849 4358849 single base substitution G A synonymous_variant T658T 1974G>A ESAD-UK 3 4359745 4359746 deletion of <=200bp AC - downstream_gene_variant ESAD-UK 3 4360112 4360112 single base substitution G A downstream_gene_variant ESAD-UK 3 4360767 4360767 single base substitution G A downstream_gene_variant ESAD-UK 3 4361022 4361022 single base substitution G A downstream_gene_variant ESAD-UK 3 4361406 4361406 single base substitution C A downstream_gene_variant ESAD-UK 3 4361428 4361428 single base substitution T C downstream_gene_variant ESAD-UK 3 4363425 4363425 single base substitution G T downstream_gene_variant ESAD-UK 3 4363664 4363664 single base substitution A C downstream_gene_variant LGG-US 3 4354791 4354791 single base substitution C T downstream_gene_variant LGG-US 3 4354791 4354791 single base substitution C T exon_variant LGG-US 3 4354791 4354791 single base substitution C T intron_variant LGG-US 3 4354791 4354791 single base substitution C T synonymous_variant C122C 366C>T LGG-US 3 4355172 4355172 single base substitution C G downstream_gene_variant LGG-US 3 4355172 4355172 single base substitution C G intron_variant LGG-US 3 4355172 4355172 single base substitution C G synonymous_variant A249A 747C>G LGG-US 3 4355408 4355408 insertion of <=200bp - T 3_prime_UTR_variant LGG-US 3 4355408 4355408 insertion of <=200bp - T downstream_gene_variant LGG-US 3 4355408 4355408 insertion of <=200bp - T frameshift_variant P189L? LGG-US 3 4355408 4355408 insertion of <=200bp - T frameshift_variant P328L? LGG-US 3 4355408 4355408 insertion of <=200bp - T frameshift_variant P92L? LGG-US 3 4355408 4355408 insertion of <=200bp - T intron_variant LGG-US 3 4358185 4358185 single base substitution A G 3_prime_UTR_variant LGG-US 3 4358185 4358185 single base substitution A G downstream_gene_variant LGG-US 3 4358185 4358185 single base substitution A G missense_variant N201S 602A>G LGG-US 3 4358185 4358185 single base substitution A G missense_variant N298S 893A>G LGG-US 3 4358185 4358185 single base substitution A G missense_variant N437S 1310A>G LINC-JP 3 4345332 4345332 single base substitution G A 5_prime_UTR_variant LINC-JP 3 4345332 4345332 single base substitution G A exon_variant LINC-JP 3 4345332 4345332 single base substitution G A intron_variant LINC-JP 3 4348384 4348384 single base substitution A G intron_variant LINC-JP 3 4353950 4353950 single base substitution T G intron_variant LINC-JP 3 4354862 4354862 single base substitution C T downstream_gene_variant LINC-JP 3 4354862 4354862 single base substitution C T exon_variant LINC-JP 3 4354862 4354862 single base substitution C T intron_variant LINC-JP 3 4354862 4354862 single base substitution C T missense_variant T146M 437C>T LIRI-JP 3 4340161 4340161 single base substitution T C upstream_gene_variant LIRI-JP 3 4341059 4341059 single base substitution T C upstream_gene_variant LIRI-JP 3 4341166 4341166 single base substitution G A upstream_gene_variant LIRI-JP 3 4341812 4341812 single base substitution C T upstream_gene_variant LIRI-JP 3 4347510 4347510 single base substitution A G intron_variant LIRI-JP 3 4348740 4348740 single base substitution A T intron_variant LIRI-JP 3 4350896 4350896 single base substitution A C intron_variant LIRI-JP 3 4352298 4352298 single base substitution T G intron_variant LIRI-JP 3 4352766 4352766 single base substitution A G intron_variant LIRI-JP 3 4353700 4353700 single base substitution T C intron_variant LIRI-JP 3 4354456 4354456 deletion of <=200bp T - intron_variant LIRI-JP 3 4355374 4355374 single base substitution A T downstream_gene_variant LIRI-JP 3 4355374 4355374 single base substitution A T exon_variant LIRI-JP 3 4355374 4355374 single base substitution A T intron_variant LIRI-JP 3 4355374 4355374 single base substitution A T missense_variant N178Y 532A>T LIRI-JP 3 4355374 4355374 single base substitution A T missense_variant N317Y 949A>T LIRI-JP 3 4355374 4355374 single base substitution A T missense_variant N81Y 241A>T LIRI-JP 3 4356689 4356689 single base substitution T A downstream_gene_variant LIRI-JP 3 4356689 4356689 single base substitution T A intron_variant LIRI-JP 3 4357929 4357929 single base substitution C T 3_prime_UTR_variant LIRI-JP 3 4357929 4357929 single base substitution C T downstream_gene_variant LIRI-JP 3 4357929 4357929 single base substitution C T exon_variant LIRI-JP 3 4357929 4357929 single base substitution C T stop_gained R116* 346C>T LIRI-JP 3 4357929 4357929 single base substitution C T stop_gained R213* 637C>T LIRI-JP 3 4357929 4357929 single base substitution C T stop_gained R352* 1054C>T LIRI-JP 3 4358258 4358258 single base substitution T A 3_prime_UTR_variant LIRI-JP 3 4358258 4358258 single base substitution T A downstream_gene_variant LIRI-JP 3 4358258 4358258 single base substitution T A synonymous_variant P322P 966T>A LIRI-JP 3 4358258 4358258 single base substitution T A synonymous_variant P461P 1383T>A LIRI-JP 3 4358261 4358261 single base substitution T G 3_prime_UTR_variant LIRI-JP 3 4358261 4358261 single base substitution T G downstream_gene_variant LIRI-JP 3 4358261 4358261 single base substitution T G missense_variant H323Q 969T>G LIRI-JP 3 4358261 4358261 single base substitution T G missense_variant H462Q 1386T>G LIRI-JP 3 4358525 4358525 single base substitution C T 3_prime_UTR_variant LIRI-JP 3 4358525 4358525 single base substitution C T downstream_gene_variant LIRI-JP 3 4358525 4358525 single base substitution C T synonymous_variant P411P 1233C>T LIRI-JP 3 4358525 4358525 single base substitution C T synonymous_variant P550P 1650C>T LIRI-JP 3 4361144 4361144 single base substitution G A downstream_gene_variant LIRI-JP 3 4361436 4361436 single base substitution A G downstream_gene_variant LIRI-JP 3 4361581 4361581 single base substitution T C downstream_gene_variant LIRI-JP 3 4361703 4361703 single base substitution A C downstream_gene_variant LIRI-JP 3 4362698 4362698 single base substitution A C downstream_gene_variant LIRI-JP 3 4363582 4363582 single base substitution A T downstream_gene_variant LUSC-KR 3 4344936 4344936 single base substitution T G upstream_gene_variant LUSC-KR 3 4345033 4345033 single base substitution G A 5_prime_UTR_variant LUSC-KR 3 4345033 4345033 single base substitution G A upstream_gene_variant LUSC-KR 3 4363268 4363268 single base substitution G C downstream_gene_variant MALY-DE 3 4341339 4341339 insertion of <=200bp - A upstream_gene_variant MALY-DE 3 4342563 4342564 deletion of <=200bp AC - upstream_gene_variant MALY-DE 3 4347798 4347798 single base substitution T C intron_variant MELA-AU 3 4339989 4339989 single base substitution G A upstream_gene_variant MELA-AU 3 4340138 4340138 single base substitution A G upstream_gene_variant MELA-AU 3 4341481 4341481 single base substitution G A upstream_gene_variant MELA-AU 3 4341684 4341684 single base substitution G A upstream_gene_variant MELA-AU 3 4341886 4341886 single base substitution C T upstream_gene_variant MELA-AU 3 4342337 4342337 single base substitution A G upstream_gene_variant MELA-AU 3 4342430 4342430 single base substitution G A upstream_gene_variant MELA-AU 3 4342563 4342564 deletion of <=200bp AC - upstream_gene_variant MELA-AU 3 4342828 4342828 single base substitution G A upstream_gene_variant MELA-AU 3 4342963 4342963 single base substitution G A upstream_gene_variant MELA-AU 3 4343017 4343017 single base substitution G A upstream_gene_variant MELA-AU 3 4343916 4343916 single base substitution C T upstream_gene_variant MELA-AU 3 4344088 4344088 single base substitution G A upstream_gene_variant MELA-AU 3 4344608 4344608 single base substitution G A upstream_gene_variant MELA-AU 3 4344620 4344620 single base substitution G A upstream_gene_variant MELA-AU 3 4344647 4344647 single base substitution A G upstream_gene_variant MELA-AU 3 4344752 4344752 single base substitution A C upstream_gene_variant MELA-AU 3 4344950 4344950 single base substitution G A upstream_gene_variant MELA-AU 3 4344982 4344982 single base substitution G A upstream_gene_variant MELA-AU 3 4345825 4345825 single base substitution T C intron_variant MELA-AU 3 4346963 4346964 multiple base substitution (>=2bp and <=200bp) TT GG intron_variant MELA-AU 3 4347158 4347158 single base substitution A C intron_variant MELA-AU 3 4347329 4347329 single base substitution C T intron_variant MELA-AU 3 4347828 4347828 insertion of <=200bp - GT intron_variant MELA-AU 3 4348187 4348187 single base substitution G A intron_variant MELA-AU 3 4348271 4348271 single base substitution T C intron_variant MELA-AU 3 4349154 4349155 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 3 4349466 4349466 single base substitution A T intron_variant MELA-AU 3 4349751 4349751 single base substitution C T intron_variant MELA-AU 3 4350623 4350623 single base substitution G A intron_variant MELA-AU 3 4350844 4350846 deletion of <=200bp ATC - intron_variant MELA-AU 3 4352157 4352157 single base substitution G C intron_variant MELA-AU 3 4352515 4352515 single base substitution C T intron_variant MELA-AU 3 4353228 4353228 single base substitution C T intron_variant MELA-AU 3 4354424 4354424 single base substitution G A intron_variant MELA-AU 3 4355387 4355387 single base substitution C T 3_prime_UTR_variant MELA-AU 3 4355387 4355387 single base substitution C T downstream_gene_variant MELA-AU 3 4355387 4355387 single base substitution C T intron_variant MELA-AU 3 4355387 4355387 single base substitution C T missense_variant P182L 545C>T MELA-AU 3 4355387 4355387 single base substitution C T missense_variant P321L 962C>T MELA-AU 3 4355387 4355387 single base substitution C T missense_variant P85L 254C>T MELA-AU 3 4356745 4356745 single base substitution A G downstream_gene_variant MELA-AU 3 4356745 4356745 single base substitution A G intron_variant MELA-AU 3 4357240 4357240 single base substitution C T downstream_gene_variant MELA-AU 3 4357240 4357240 single base substitution C T intron_variant MELA-AU 3 4357511 4357512 multiple base substitution (>=2bp and <=200bp) AC TT downstream_gene_variant MELA-AU 3 4357511 4357512 multiple base substitution (>=2bp and <=200bp) AC TT intron_variant MELA-AU 3 4358831 4358831 single base substitution C T 3_prime_UTR_variant MELA-AU 3 4358831 4358831 single base substitution C T downstream_gene_variant MELA-AU 3 4358831 4358831 single base substitution C T synonymous_variant F513F 1539C>T MELA-AU 3 4358831 4358831 single base substitution C T synonymous_variant F652F 1956C>T MELA-AU 3 4360208 4360208 single base substitution G A downstream_gene_variant MELA-AU 3 4360562 4360562 single base substitution T C downstream_gene_variant MELA-AU 3 4360888 4360888 single base substitution T C downstream_gene_variant MELA-AU 3 4361061 4361061 insertion of <=200bp - A downstream_gene_variant MELA-AU 3 4361123 4361123 single base substitution G C downstream_gene_variant MELA-AU 3 4361342 4361342 single base substitution C T downstream_gene_variant MELA-AU 3 4361668 4361669 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 3 4362036 4362037 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 3 4362518 4362518 single base substitution G A downstream_gene_variant MELA-AU 3 4362879 4362881 deletion of <=200bp AGA - downstream_gene_variant MELA-AU 3 4363169 4363169 single base substitution A G downstream_gene_variant MELA-AU 3 4363200 4363200 single base substitution G A downstream_gene_variant ORCA-IN 3 4358848 4358848 single base substitution C T 3_prime_UTR_variant ORCA-IN 3 4358848 4358848 single base substitution C T downstream_gene_variant ORCA-IN 3 4358848 4358848 single base substitution C T missense_variant T519M 1556C>T ORCA-IN 3 4358848 4358848 single base substitution C T missense_variant T658M 1973C>T OV-AU 3 4343008 4343008 single base substitution G C upstream_gene_variant OV-AU 3 4348902 4348902 single base substitution T G intron_variant OV-AU 3 4358931 4358931 single base substitution T C 3_prime_UTR_variant OV-AU 3 4358931 4358931 single base substitution T C downstream_gene_variant PACA-AU 3 4346380 4346380 insertion of <=200bp - T intron_variant PACA-AU 3 4354034 4354034 single base substitution A G intron_variant PACA-AU 3 4354905 4354905 single base substitution G A downstream_gene_variant PACA-AU 3 4354905 4354905 single base substitution G A exon_variant PACA-AU 3 4354905 4354905 single base substitution G A intron_variant PACA-AU 3 4354905 4354905 single base substitution G A synonymous_variant P160P 480G>A PACA-AU 3 4360028 4360028 single base substitution T C downstream_gene_variant PACA-AU 3 4363907 4363907 single base substitution C G downstream_gene_variant PACA-AU 3 4363941 4363941 single base substitution C G downstream_gene_variant PACA-CA 3 4340175 4340175 single base substitution G A upstream_gene_variant PACA-CA 3 4341736 4341736 single base substitution A T upstream_gene_variant PACA-CA 3 4348851 4348851 single base substitution C T intron_variant PACA-CA 3 4348957 4348957 single base substitution G A intron_variant PACA-CA 3 4348958 4348958 single base substitution C A intron_variant PACA-CA 3 4351598 4351598 single base substitution G A intron_variant PACA-CA 3 4353581 4353581 deletion of <=200bp A - intron_variant PACA-CA 3 4355985 4355985 single base substitution G A 3_prime_UTR_variant PACA-CA 3 4355985 4355985 single base substitution G A downstream_gene_variant PACA-CA 3 4355985 4355985 single base substitution G A intron_variant PACA-CA 3 4361637 4361637 single base substitution A G downstream_gene_variant PACA-CA 3 4363050 4363050 deletion of <=200bp A - downstream_gene_variant PBCA-DE 3 4342563 4342564 deletion of <=200bp AC - upstream_gene_variant PBCA-DE 3 4350281 4350281 single base substitution C G intron_variant PBCA-DE 3 4351752 4351752 single base substitution G A intron_variant PBCA-DE 3 4354696 4354696 single base substitution C T exon_variant PBCA-DE 3 4354696 4354696 single base substitution C T intron_variant PBCA-DE 3 4354696 4354696 single base substitution C T missense_variant R91C 271C>T PBCA-DE 3 4356559 4356559 insertion of <=200bp - A downstream_gene_variant PBCA-DE 3 4356559 4356559 insertion of <=200bp - A intron_variant PBCA-DE 3 4356983 4356983 single base substitution A G downstream_gene_variant PBCA-DE 3 4356983 4356983 single base substitution A G intron_variant PRAD-UK 3 4353440 4353440 single base substitution T C intron_variant PRAD-UK 3 4355798 4355798 single base substitution G C 3_prime_UTR_variant PRAD-UK 3 4355798 4355798 single base substitution G C downstream_gene_variant PRAD-UK 3 4355798 4355798 single base substitution G C intron_variant PRAD-UK 3 4357918 4357918 single base substitution A G 3_prime_UTR_variant PRAD-UK 3 4357918 4357918 single base substitution A G downstream_gene_variant PRAD-UK 3 4357918 4357918 single base substitution A G exon_variant PRAD-UK 3 4357918 4357918 single base substitution A G missense_variant K112R 335A>G PRAD-UK 3 4357918 4357918 single base substitution A G missense_variant K209R 626A>G PRAD-UK 3 4357918 4357918 single base substitution A G missense_variant K348R 1043A>G RECA-EU 3 4343687 4343687 single base substitution C A upstream_gene_variant SKCA-BR 3 4349436 4349436 single base substitution C T intron_variant SKCA-BR 3 4349756 4349757 deletion of <=200bp TG - intron_variant SKCA-BR 3 4353298 4353298 single base substitution C G intron_variant SKCA-BR 3 4353817 4353817 single base substitution T C intron_variant SKCA-BR 3 4357730 4357731 deletion of <=200bp CA - downstream_gene_variant SKCA-BR 3 4357730 4357731 deletion of <=200bp CA - intron_variant SKCM-US 3 4345113 4345113 single base substitution A C exon_variant SKCM-US 3 4345113 4345113 single base substitution A C missense_variant K20T 59A>C SKCM-US 3 4345113 4345113 single base substitution A C upstream_gene_variant SKCM-US 3 4354724 4354724 single base substitution C T exon_variant SKCM-US 3 4354724 4354724 single base substitution C T intron_variant SKCM-US 3 4354724 4354724 single base substitution C T missense_variant S100L 299C>T SKCM-US 3 4354988 4354988 single base substitution C T downstream_gene_variant SKCM-US 3 4354988 4354988 single base substitution C T intron_variant SKCM-US 3 4354988 4354988 single base substitution C T missense_variant S188F 563C>T SKCM-US 3 4355387 4355387 single base substitution C T 3_prime_UTR_variant SKCM-US 3 4355387 4355387 single base substitution C T downstream_gene_variant SKCM-US 3 4355387 4355387 single base substitution C T intron_variant SKCM-US 3 4355387 4355387 single base substitution C T missense_variant P182L 545C>T SKCM-US 3 4355387 4355387 single base substitution C T missense_variant P321L 962C>T SKCM-US 3 4355387 4355387 single base substitution C T missense_variant P85L 254C>T SKCM-US 3 4355407 4355407 single base substitution C T 3_prime_UTR_variant SKCM-US 3 4355407 4355407 single base substitution C T downstream_gene_variant SKCM-US 3 4355407 4355407 single base substitution C T intron_variant SKCM-US 3 4355407 4355407 single base substitution C T missense_variant P189S 565C>T SKCM-US 3 4355407 4355407 single base substitution C T missense_variant P328S 982C>T SKCM-US 3 4355407 4355407 single base substitution C T missense_variant P92S 274C>T STAD-US 3 4345101 4345101 single base substitution A G exon_variant STAD-US 3 4345101 4345101 single base substitution A G missense_variant E16G 47A>G STAD-US 3 4345101 4345101 single base substitution A G upstream_gene_variant STAD-US 3 4354664 4354671 deletion of <=200bp CTCCCTGC - exon_variant STAD-US 3 4354664 4354671 deletion of <=200bp CTCCCTGC - frameshift_variant TPC80 STAD-US 3 4354664 4354671 deletion of <=200bp CTCCCTGC - intron_variant STAD-US 3 4355148 4355148 single base substitution A G downstream_gene_variant STAD-US 3 4355148 4355148 single base substitution A G intron_variant STAD-US 3 4355148 4355148 single base substitution A G synonymous_variant V241V 723A>G THCA-SA 3 4345033 4345033 single base substitution G A 5_prime_UTR_variant THCA-SA 3 4345033 4345033 single base substitution G A upstream_gene_variant THCA-SA 3 4355265 4355265 single base substitution T C downstream_gene_variant THCA-SA 3 4355265 4355265 single base substitution T C intron_variant THCA-SA 3 4355265 4355265 single base substitution T C synonymous_variant H280H 840T>C UCEC-US 3 4354885 4354885 single base substitution C T downstream_gene_variant UCEC-US 3 4354885 4354885 single base substitution C T exon_variant UCEC-US 3 4354885 4354885 single base substitution C T intron_variant UCEC-US 3 4354885 4354885 single base substitution C T missense_variant R154C 460C>T UCEC-US 3 4355199 4355199 single base substitution C A downstream_gene_variant UCEC-US 3 4355199 4355199 single base substitution C A intron_variant UCEC-US 3 4355199 4355199 single base substitution C A synonymous_variant L258L 774C>A UCEC-US 3 4358024 4358024 single base substitution A G 3_prime_UTR_variant UCEC-US 3 4358024 4358024 single base substitution A G downstream_gene_variant UCEC-US 3 4358024 4358024 single base substitution A G exon_variant UCEC-US 3 4358024 4358024 single base substitution A G synonymous_variant E147E 441A>G UCEC-US 3 4358024 4358024 single base substitution A G synonymous_variant E244E 732A>G UCEC-US 3 4358024 4358024 single base substitution A G synonymous_variant E383E 1149A>G UCEC-US 3 4358103 4358103 single base substitution T A 3_prime_UTR_variant UCEC-US 3 4358103 4358103 single base substitution T A downstream_gene_variant UCEC-US 3 4358103 4358103 single base substitution T A missense_variant S174T 520T>A UCEC-US 3 4358103 4358103 single base substitution T A missense_variant S271T 811T>A UCEC-US 3 4358103 4358103 single base substitution T A missense_variant S410T 1228T>A UCEC-US 3 4358243 4358243 single base substitution C T 3_prime_UTR_variant UCEC-US 3 4358243 4358243 single base substitution C T downstream_gene_variant UCEC-US 3 4358243 4358243 single base substitution C T synonymous_variant L317L 951C>T UCEC-US 3 4358243 4358243 single base substitution C T synonymous_variant L456L 1368C>T UCEC-US 3 4358262 4358262 insertion of <=200bp - A 3_prime_UTR_variant UCEC-US 3 4358262 4358262 insertion of <=200bp - A downstream_gene_variant UCEC-US 3 4358262 4358262 insertion of <=200bp - A frameshift_variant E324R? UCEC-US 3 4358262 4358262 insertion of <=200bp - A frameshift_variant E463R? UCEC-US 3 4358391 4358391 single base substitution C T 3_prime_UTR_variant UCEC-US 3 4358391 4358391 single base substitution C T downstream_gene_variant UCEC-US 3 4358391 4358391 single base substitution C T stop_gained R367* 1099C>T UCEC-US 3 4358391 4358391 single base substitution C T stop_gained R506* 1516C>T UCEC-US 3 4358392 4358392 single base substitution G A 3_prime_UTR_variant UCEC-US 3 4358392 4358392 single base substitution G A downstream_gene_variant UCEC-US 3 4358392 4358392 single base substitution G A missense_variant R367Q 1100G>A UCEC-US 3 4358392 4358392 single base substitution G A missense_variant R506Q 1517G>A UCEC-US 3 4358564 4358564 single base substitution C T 3_prime_UTR_variant UCEC-US 3 4358564 4358564 single base substitution C T downstream_gene_variant UCEC-US 3 4358564 4358564 single base substitution C T synonymous_variant I424I 1272C>T UCEC-US 3 4358564 4358564 single base substitution C T synonymous_variant I563I 1689C>T UCEC-US 3 4358755 4358755 single base substitution T G 3_prime_UTR_variant UCEC-US 3 4358755 4358755 single base substitution T G downstream_gene_variant UCEC-US 3 4358755 4358755 single base substitution T G missense_variant F488C 1463T>G UCEC-US 3 4358755 4358755 single base substitution T G missense_variant F627C 1880T>G

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-A3-3311-01 COSM1137030 c.637A>G p.T213A Substitution - Missense 3:4313378-4313378 + TCGA-AZ-4313-01 COSM5138689 c.1482G>A p.T494T Substitution - coding silent 3:4316673-4316673 + TCGA-E1-5307-01 COSM3974417 c.366C>T p.C122C Substitution - coding silent 3:4313107-4313107 + T1221 COSM4725216 c.4T>A p.F2I Substitution - Missense 3:4303374-4303374 + TCGA-EE-A2GL-06 COSM3594175 c.982C>T p.P328S Substitution - Missense 3:4313723-4313723 + 2474090 COSM3066679 c.1325C>T p.T442M Substitution - Missense 3:4316516-4316516 + TCGA-Q1-A73S-01 COSM4836654 c.1222C>T p.R408W Substitution - Missense 3:4316413-4316413 + TTC466 COSM4584369 c.1009T>C p.L337L Substitution - coding silent 3:4313750-4313750 + p1_V-1 COSM1738265 c.677G>C p.C226S Substitution - Missense 3:4313418-4313418 + TCGA-D5-6928-01 COSM1423180 c.450C>T p.G150G Substitution - coding silent 3:4313191-4313191 + TCGA-HU-A4G8-01 COSM4117703 c.47A>G p.E16G Substitution - Missense 3:4303417-4303417 + RK210_C01 COSM3767433 c.1650C>T p.P550P Substitution - coding silent 3:4316841-4316841 + TCGA-EE-A2M6-06 COSM3594173 c.962C>T p.P321L Substitution - Missense 3:4313703-4313703 + OSCC-GB_01170111 COSM5790427 c.1973C>T p.T658M Substitution - Missense 3:4317164-4317164 + TCGA-EK-A2R8-01 COSM4822875 c.1264G>A p.E422K Substitution - Missense 3:4316455-4316455 + TCGA-BS-A0UV-01 COSM1044882 c.1689C>T p.I563I Substitution - coding silent 3:4316880-4316880 + TCGA-AP-A0LE-01 COSM1044880 c.1517G>A p.R506Q Substitution - Missense 3:4316708-4316708 + TCGA-AA-3977-01 COSM297625 c.1959C>T p.V653V Substitution - coding silent 3:4317150-4317150 + p1_I-2 COSM1738265 c.677G>C p.C226S Substitution - Missense 3:4313418-4313418 + HCC52 COSM1617606 c.437C>T p.T146M Substitution - Missense 3:4313178-4313178 + TCGA-QH-A65S-01 COSM4420522 c.747C>G p.A249A Substitution - coding silent 3:4313488-4313488 + T636 COSM4725218 c.747C>A p.A249A Substitution - coding silent 3:4313488-4313488 + PT55 COSM5941853 c.720G>A p.M240I Substitution - Missense 3:4313461-4313461 + TCGA-FW-A3R5-06 COSM3916067 c.563C>T p.S188F Substitution - Missense 3:4313304-4313304 + HCT15 COSM3066661 c.362T>A p.L121Q Substitution - Missense 3:4313103-4313103 + TARGET-30-PAPTAN COSM1287835 c.4T>C p.F2L Substitution - Missense 3:4303374-4303374 + H23 COSM1196368 c.1984G>A p.A662T Substitution - Missense 3:4317175-4317175 + Pat_06_B COSM5864548 c.433A>G p.K145E Substitution - Missense 3:4313174-4313174 + ICGC_PA97 COSM3670320 c.271C>T p.R91C Substitution - Missense 3:4313012-4313012 + TCGA-FG-8186-01 COSM3974419 c.1310A>G p.N437S Substitution - Missense 3:4316501-4316501 + TCGA-B5-A0JY-01 COSM1044882 c.1689C>T p.I563I Substitution - coding silent 3:4316880-4316880 + CSCC-44-T COSM4493096 c.409C>T p.L137L Substitution - coding silent 3:4313150-4313150 + sysucc-880T COSM4117705 c.723A>G p.V241V Substitution - coding silent 3:4313464-4313464 + ESCC_168 COSM5648774 c.1666T>A p.S556T Substitution - Missense 3:4316857-4316857 + PD12805a COSM3770183 c.936_941CATCAG>CTCA p.I313fs*5 Complex - frameshift 3:4313677-4313682 + SC_9104 COSM5569219 c.438G>A p.T146T Substitution - coding silent 3:4313179-4313179 + TCGA-D9-A6EC-06 COSM4405311 c.59A>C p.K20T Substitution - Missense 3:4303429-4303429 + TCGA-D1-A16X-01 COSM1044874 c.1368C>T p.L456L Substitution - coding silent 3:4316559-4316559 + SNU-C2B COSM4615338 c.441_442insA p.G150fs*18 Insertion - Frameshift 3:4313182-4313183 + RK261_C02 COSM4943972 c.949A>T p.N317Y Substitution - Missense 3:4313690-4313690 + PD13761a COSM5790427 c.1973C>T p.T658M Substitution - Missense 3:4317164-4317164 + TCGA-AM-5821-01 COSM3696095 c.1745G>A p.G582D Substitution - Missense 3:4316936-4316936 + TCGA-AM-5820-01 COSM3760096 c.272G>A p.R91H Substitution - Missense 3:4313013-4313013 + TCGA-A6-5661-01 COSM1423181 c.480G>A p.P160P Substitution - coding silent 3:4313221-4313221 + pfg127T COSM4765023 c.1403_1404insA p.N470fs*5 Insertion - Frameshift 3:4316594-4316595 + TCGA-AG-A002-01 COSM263611 c.1006C>T p.R336* Substitution - Nonsense 3:4313747-4313747 + TCGA-BS-A0UV-01 COSM1044884 c.1880T>G p.F627C Substitution - Missense 3:4317071-4317071 + TCGA-AP-A0LE-01 COSM1044872 c.1228T>A p.S410T Substitution - Missense 3:4316419-4316419 + TCGA-RU-A8FL-01 COSM5188532 c.1717C>G p.L573V Substitution - Missense 3:4316908-4316908 + p1_IV-2 COSM1738265 c.677G>C p.C226S Substitution - Missense 3:4313418-4313418 + TCGA-B2-4102-01 COSM1137029 c.45G>A p.A15A Substitution - coding silent 3:4303415-4303415 + CSCC-27-T COSM4480438 c.241C>T p.P81S Substitution - Missense 3:4312982-4312982 + SJHGG041_D COSM4969671 c.1314C>T p.V438V Substitution - coding silent 3:4316505-4316505 + HCC52T COSM1617606 c.437C>T p.T146M Substitution - Missense 3:4313178-4313178 + TCGA-DG-A2KL-01 COSM4851409 c.1806G>C p.L602F Substitution - Missense 3:4316997-4316997 + p1_IV-1 COSM1738265 c.677G>C p.C226S Substitution - Missense 3:4313418-4313418 + TCGA-AN-A0AK-01 COSM1423177 c.344delT p.F116fs*58 Deletion - Frameshift 3:4313085-4313085 + TCGA-AX-A05Z-01 COSM1044870 c.1149A>G p.E383E Substitution - coding silent 3:4316340-4316340 + TCGA-ER-A3PL-06 COSM3594171 c.299C>T p.S100L Substitution - Missense 3:4313040-4313040 + RK308_C01 COSM3767432 c.1383T>A p.P461P Substitution - coding silent 3:4316574-4316574 + TCGA-AP-A0LH-01 COSM1044876 c.1387_1388insA p.L464fs*3 Insertion - Frameshift 3:4316578-4316579 + S10-47754-TP COSM4991923 c.1360delA p.K455fs*10 Deletion - Frameshift 3:4316551-4316551 + TCGA-DG-A2KH-01 COSM4851274 c.64G>A p.E22K Substitution - Missense 3:4303434-4303434 + DLD1 COSM3066661 c.362T>A p.L121Q Substitution - Missense 3:4313103-4313103 + 2474089 COSM3066679 c.1325C>T p.T442M Substitution - Missense 3:4316516-4316516 + EOPC-02_tumor COSM3716600 c.471A>G p.E157E Substitution - coding silent 3:4313212-4313212 + p1_IV-3 COSM1738265 c.677G>C p.C226S Substitution - Missense 3:4313418-4313418 + 8067240 COSM1423181 c.480G>A p.P160P Substitution - coding silent 3:4313221-4313221 + RK280_C01 COSM4944390 c.1386T>G p.H462Q Substitution - Missense 3:4316577-4316577 + TCGA-AP-A0LM-01 COSM1044866 c.460C>T p.R154C Substitution - Missense 3:4313201-4313201 + sysucc-311T COSM5465880 c.932C>T p.S311L Substitution - Missense 3:4313673-4313673 + TCGA-CK-5916-01 COSM1423176 c.96C>T p.C32C Substitution - coding silent 3:4303466-4303466 + L21 COSM5369488 c.367C>T p.R123* Substitution - Nonsense 3:4313108-4313108 + TCGA-A8-A09N-01 COSM446525 c.947G>C p.G316A Substitution - Missense 3:4313688-4313688 + TCGA-A3-3346-01 COSM1495585 c.679G>A p.E227K Substitution - Missense 3:4313420-4313420 + TCGA-13-1495-01 COSM72608 c.565G>A p.D189N Substitution - Missense 3:4313306-4313306 + TCGA-B5-A0JY-01 COSM1044868 c.774C>A p.L258L Substitution - coding silent 3:4313515-4313515 + TCGA-BR-4361-01 COSM4117705 c.723A>G p.V241V Substitution - coding silent 3:4313464-4313464 + pfg129T COSM4749011 c.604A>G p.N202D Substitution - Missense 3:4313345-4313345 + Pat_01_B COSM5369488 c.367C>T p.R123* Substitution - Nonsense 3:4313108-4313108 + RK308_C01 COSM3767431 c.1054C>T p.R352* Substitution - Nonsense 3:4316245-4316245 + 2492729 COSM5725863 c.341C>T p.P114L Substitution - Missense 3:4313082-4313082 + TCGA-AA-3815-01 COSM1423179 c.442delA p.G150fs*24 Deletion - Frameshift 3:4313183-4313183 + BD165T COSM5506721 c.280G>T p.E94* Substitution - Nonsense 3:4313021-4313021 + TCGA-CM-5861-01 COSM1423177 c.344delT p.F116fs*58 Deletion - Frameshift 3:4313085-4313085 + TCGA-B5-A0JV-01 COSM1044878 c.1516C>T p.R506* Substitution - Nonsense 3:4316707-4316707 + B86-Tumor COSM4005544 c.751G>C p.D251H Substitution - Missense 3:4313492-4313492 + LIM2551 COSM4644532 c.219C>T p.P73P Substitution - coding silent 3:4312960-4312960 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.475244;Hs.475300 3p26.1 609834 1230906|dbSNP|BC008931|C/G|coding|Leu115Val|611|Candidate; 1231320|dbSNP|BC008931|C/G|coding|Leu115Val|611|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer - A Frameshift p.L464Afs*3 c.1388dupA 3 4358263 UCEC A G Missense p.N437S c.1310A>G 3 4358185 LGG A G Missense p.T213A c.637A>G 3 4355062 RCCC CC TT Missense p.P328S c.981_982delinsTT 3 4355406 CM C G Missense p.L283V c.847C>G 3 4355272 HNSC C T Missense p.L267F c.799C>T 3 4355224 CM C T Missense p.P307L c.920C>T 3 4355345 CM C T Missense p.P321L c.962C>T 3 4355387 CM C T Nonsense p.R506* c.1516C>T 3 4358391 UCEC C T Synonymous p.C122C c.366C>T 3 4354791 LGG C T Synonymous p.S88S c.264C>T 3 4354689 CM CT TC Missense p.S176F c.527_528delinsTC 3 4354952 CM G A Missense p.D189N c.565G>A 3 4354990 OV G A Missense p.R506Q c.1517G>A 3 4358392 UCEC G A Missense p.V412I c.1234G>A 3 4358109 CM G C Missense p.G316A c.947G>C 3 4355372 BRCA GG AA Missense p.G325N c.973_974delinsAA 3 4355398 CM G T Missense p.D415Y c.1243G>T 3 4358118 LUAD T A Missense p.S410T c.1228T>A 3 4358103 UCEC T C Missense p.F2L c.4T>C 3 4345058 NB