PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus KLHL32 SPAG8 25416956 biogrid,intact exp P P P P GP CDK4 KLHL32 23718855 biogrid exp P G GP P G P P GP P P HSP90AB1 KLHL32 22939624 intact exp P G GP P G P P GP P P C1orf94 KLHL32 25416956 biogrid,intact exp P P P P P P P APP KLHL32 21832049 biogrid exp P G GP P G GP P NUDCD3 KLHL32 25036637 intact exp P G GP P G P P GP P P REL KLHL32 25416956 biogrid,intact exp G GP P G P GP P P HSP90AA1 KLHL32 22939624 biogrid exp P G GP P G GP CRX KLHL32 25416956 biogrid,intact exp P P P P P P P P KLHL32 PARVG 25416956 biogrid,intact exp P P P G P P P P P TCF4 KLHL32 25416956 biogrid,intact exp P G GP P G P P GP P P NUP62 KLHL32 25416956 biogrid,intact exp P G GP P G P P GP P P KLHL32 ZBTB3 23023127 pred P P P G P P P P P KBTBD6 KLHL32 23023127 pred P G GP P G P P GP KBTBD11 KLHL32 23023127 pred P G GP P G P P GP P P KLHL2 KLHL32 23023127 pred G G G P P G ZBTB44 KLHL32 23023127 pred P G GP P G P P GP P P KLHL32 KLHL3 23023127 pred P G GP P G P P GP P P BTBD6 KLHL32 23023127 pred G G P G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96NJ5 P05067-7 pull down 21832049 direct interaction X 2 Q96NJ5 P15884-6 two hybrid 25416956 direct interaction X 2 Q96NJ5 A0A024QZF1 two hybrid 25416956 direct interaction X 2 Q96NJ5 A0A024R4U4 two hybrid 25416956 direct interaction X 2 Q96NJ5 Q6P1W5 two hybrid 25416956 direct interaction X 2 Q96NJ5 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q96NJ5 A0A024RBB6 affinity chromatography technology 23718855 physical association X 2 Q96NJ5 O43186 two hybrid 25416956 direct interaction X 2 Q96NJ5 Q04864 two hybrid 25416956 direct interaction X 2 Q96NJ5 Q99932 two hybrid 25416956 direct interaction X 2 Q96NJ5 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2 Q96NJ5 Q8IVD9 luminescence based mammalian interactome mapping 25036637 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality CRX KLHL32 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT HSP90AB1 KLHL32 22939624 0729 HT TCF4 KLHL32 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT NUP62 KLHL32 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT REL KLHL32 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT C1ORF94 KLHL32 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT NUDCD3 KLHL32 25036637 0729 HT KLHL32 SPAG8 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KLHL32 PARVG 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96NJ5 O43186 KLHL32 CRX 0.183 25416956 Q96NJ5 P15884 KLHL32 TCF4 0.183 25416956 Q96NJ5 Q04864 KLHL32 REL 0.183 25416956 Q9HBI0 Q96NJ5 PARVG KLHL32 0.183 25416956 Q96NJ5 P07900 KLHL32 HSP90AA1 0.126 22939624 Q96NJ5 Q6P1W5 KLHL32 C1ORF94 0.183 25416956 Q96NJ5 P37198 KLHL32 NUP62 0.183 25416956 Q96NJ5 P11802 KLHL32 CDK4 0.21 23718855 Q96NJ5 P08238 KLHL32 HSP90AB1 0.126 22939624 Q96NJ5 P05067 KLHL32 APP 0.183 21832049 Q96NJ5 Q8IVD9 KLHL32 NUDCD3 0.126 25036637 Q99932 Q96NJ5 SPAG8 KLHL32 0.183 25416956

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CRX KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database APP KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database CDK4 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database TCF4 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database NUP62 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database REL KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database SF1 KLHL32 MI:0362 inference MI:0461 interaction database C1orf94 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database NUDCD3 KLHL32 MI:0045 experimental interaction detection MI:0461 interaction database KLHL32 SPAG8 MI:0045 experimental interaction detection MI:0461 interaction database KLHL32 PARVG MI:0045 experimental interaction detection MI:0461 interaction database