PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Cenpc Rbbp7 21274006 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfcp2l1 Rbbp7 20362541 biogrid,intact exp G G G G G G G G G G G G G G Rbbp7 Nanog 18454139 biogrid exp H3f3a, H3f3b Rbbp7 20211137 intact exp P Ywhae Rbbp7 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rbbp7 19189660 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gata1 Rbbp7 15920471 biogrid exp G G G G G G G Zfpm1 Rbbp7 19654328 biogrid,i2d exp G G G G G G G G G G G G G G G G G G G G G G G G Tet1 Rbbp7 21490601 biogrid exp G Tet2 Rbbp7 21490601 biogrid exp Tcf3 Rbbp7 22354994 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Rnf2 17296600 biogrid,intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G L3mbtl2 Rbbp7 22770845 biogrid exp Pou5f1 Rbbp7 22083510,20362541,18454139 biogrid,intact exp Rbbp7 Sall4 20362541 biogrid,intact exp Hdac1 Rbbp7 20211142 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mta1 18454139 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox2 Rbbp7 21532573 intact exp, ortho G G G G G G G G G G G Rbbp7 Ezh2 20064376,23624931 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Eed 20064376 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Suv39h1 Rbbp7 11788710 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Rbbp7 20211137 intact exp, ortho P G G G G Hist1h3a, Hist1h3g, Hist1h3h, Hist1h3i Rbbp7 20211137 intact exp, ortho P Hdac2 Rbbp7 18454139 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Suz12 22438827 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mta2 15920471,18454139 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arid4b Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vhl Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Hdac5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Ncor1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Rps6kb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Hspe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mis18a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Park7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Morf4l2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Hcfc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Rbl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Dnmt3b Rbbp7 ortho G G G G G G G G G G G Rbbp7 Zeb2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Brms1 ortho G G G G G G G G G G G G G G G G G Sap25 Rbbp7 ortho Mtf2 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kdm5a Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Morf4l1 Rbbp7 ortho P Esr1 Rbbp7 ortho G G G G G Rbbp7 Sall2 ortho G G G G G G G G G G G G G Kmt2a Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sap30 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Dhx30 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mbd3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Chd3 Rbbp7 ortho P Rbbp7 Sall1 ortho G G Rbbp7 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tsta3 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Phf6 ortho Nr1i2 Rbbp7 ortho G G G G G Crebbp Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Appl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Znf512b ortho Rbbp7 Shb ortho P Rbbp7 Smarca2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rb1 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Gatad2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Taf6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Appl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Nacc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Cbx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nkx3-2 Rbbp7 ortho Rbbp7 Suds3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Tcf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Kdm5b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Gatad1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Fam64a ortho G G G Nme2 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Zfpm2 ortho G G G G G G G G G G G G G Rbbp7 Ikbke ortho G G G G G G G G G G G G G Rbbp7 Gatad2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Znf827 Rbbp7 ortho Cul4a Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mbd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sin3a Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Phf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Rbbp7 ortho G G G G G G G G G G G G G Rbbp7 Mybbp1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Phf19 ortho G G G G G G G G G G G Rbbp7 Jarid2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Chrac1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Phf20l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Zmynd8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chd5 Rbbp7 ortho P Sumo2 Rbbp7 ortho P Sirt6 Rbbp7 ortho Protein Arid4a Rbbp7 ortho Twist1 Rbbp7 ortho G G G Rbbp7 Hjurp ortho Rbbp7 Asf1b ortho G G G G G G G G G G G G G G G G Rbbp7 Aebp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Smarca5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Topors ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Cdc5l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wdr1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Eaf2 ortho G G G G G G Rbbp7 Aim2 ortho G G Rbbp7 Sap130 ortho Rbbp7 Sin3b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Hmg20a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Myg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Ing1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Rbbp7 ortho P G G G G G G G G G G G G G G Ilk Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Banf1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Nasp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk2ap1 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Loxl2 Rbbp7 ortho G G G G Rbp1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Traf6 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G Rbbp7 Npat ortho Rbbp7 Hist2h2ac ortho P Ddb1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Ing2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Smarca1 ortho G G G G G G G G G G G G G G G Rbbp7 Asf1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxk2 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mrgbp ortho Rbbp7 Rpn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Bcl11b ortho G G G G G G G G G G G G G Rbbp7 Bap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Hat1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Zgpat ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bahcc1 Rbbp7 ortho Rbbp7 Kdm1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Znf521 ortho G G G G G G G G G G G G G G G G G G G G Idh1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Bcl11a ortho G G G G G G G G G G G G G G G G G G G G Rbbp7 Lin9 ortho G G G G G Gm1103 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Nlrp3 ortho G G G Rbbp7 Thop1 ortho G G G G G G G G G G G G G G G G G G G G G Rbbp7 Znf423 ortho G G G G G G Rbbp7 Oxct1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brms1l Rbbp7 ortho Nme1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Fam60a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abce1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Bap18 ortho P Rbbp7 Nr2e3 ortho G Rbbp7 Snw1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac3 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mta3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Bptf Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Phf12 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Lrrk2 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G Tal1 Rbbp7 ortho G G G G G G Dck Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Grb2 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Usf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxk1 Rbbp7 ortho P G G G Rbbp7 Zfp219 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sap30l Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Chd4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Cdk9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Wrap53 ortho G G G G G G G G G G G G G G G G G G G G G Rbbp7 Mbd3l1 ortho G Ccdc8 Rbbp7 ortho Adss Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xrcc6 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Shprh ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Gnl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Atg10 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Nr2c1 Rbbp7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cenpa Rbbp7 ortho G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q60973 Q80U70 affinity chromatography technology 22438827 physical association X 2 Q60973 P63166 affinity chromatography technology 19189660 physical association X 2 Q60973 Q4JK59 affinity chromatography technology 21490601 physical association X 2 Q60973 affinity chromatography technology 21490601 physical association X 2 Q60973 O35615 affinity chromatography technology 19654328 physical association X 2 Q60973 affinity chromatography technology 20362541 physical association X 2 Q60973 Q3UNW5 affinity chromatography technology 20362541 physical association X 2 Q60973 affinity chromatography technology 20064376 physical association X 2 Q60973 A2RS90 affinity chromatography technology 18454139 physical association X 2 Q60973 P70288 affinity chromatography technology 18454139 physical association X 2 Q60973 Q9CQJ4 affinity chromatography technology 17296600 physical association X 2 Q60973 E9PVV2 affinity chromatography technology 22354994 physical association X 2 Q60973 affinity chromatography technology 22083510 physical association X 2 Q60973 P59178 affinity chromatography technology 22770845 physical association X 2 Q60973 P59178 affinity chromatography technology 22770845 physical association X 2 Q60973 O09106 two hybrid 20211142 direct interaction X 2 Q60973 affinity chromatography technology 20362541 physical association X 2 Q60973 Q921E6 affinity chromatography technology 20064376 physical association X 2 Q60973 F8WHY8 affinity chromatography technology 18454139 physical association X 2 Q60973 Q9R190 affinity chromatography technology 18454139 physical association X 2 Q60973 affinity chromatography technology 18454139 physical association X 2 Q60973 P17679 affinity chromatography technology 15920471 physical association X 2 Q60973 Q9R190 affinity chromatography technology 15920471 physical association X 2 Q60973 affinity chromatography technology 11003653 association C 14 Q60973 chromatography technology 11003653 association C 14 Q60973 coimmunoprecipitation 15920471 association C 13 Q60973 anti tag coimmunoprecipitation 14612411 association C 7 Q60973 cosedimentation 16615898 colocalization C 1216 Q60973 anti tag coimmunoprecipitation 20064376 association C 12 Q60973 pull down 23624931 association C 129 Q60973 anti tag coimmunoprecipitation 20362541 association C 93 Q60973 anti tag coimmunoprecipitation 20064376 association C 12 Q60973 anti bait coimmunoprecipitation 21532573 association C 30 Q60973 pull down 11788710 association C 5 Q60973 pull down 17296600 association C 52 Q60973 anti tag coimmunoprecipitation 20064376 association C 9 Q60973 anti tag coimmunoprecipitation 20064376 association C 10 Q60973 anti tag coimmunoprecipitation 21532573 association C 50 Q60973 anti tag coimmunoprecipitation 20362541 association C 42 Q60973 anti tag coimmunoprecipitation 20362541 association C 45

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Tet1 Rbbp7 MI:0004(affinity chromatography technology) 21490601 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326087 bait prey Rbbp7 Sall4 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20362541 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_107198|UniProt_170697|BIOGRID_313970 prey|prey|prey bait|bait|bait Rbbp7 Ezh2 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 16615898,20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact) UniProt_167137|BIOGRID_314310|UniProt_170408 neutral component|prey|prey neutral component|bait|bait Rbbp7 Mta2 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 15920471,16615898,18454139 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact) UniProt_167137|UniProt_167121|UniProt_167133|UniProt_167118|BIOGRID_314784|BIOGRID_314935|UniProt_167125|UniProt_167129 neutral component|neutral component|neutral component|neutral component|prey|prey|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|bait|bait|neutral component|neutral component Zfpm1 Rbbp7 MI:0004(affinity chromatography technology) 19654328 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_312809 bait prey Pou5f1 Rbbp7 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18454139,20362541,22083510 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact) UniProt_170695|BIOGRID_320993|BIOGRID_313915|BIOGRID_314790|UniProt_107196|UniProt_107195|UniProt_170681 bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey Tfcp2l1 Rbbp7 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20362541 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_314016|UniProt_170696|UniProt_107197 bait|bait|bait prey|prey|prey Rbbp7 Rnf2 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0096(pull down)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 16615898,17296600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0914(association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_167137|BIOGRID_315700|UniProt_167121|UniProt_166511|UniProt_167117|UniProt_167133|UniProt_167125 neutral component|prey|neutral component|prey|neutral component|neutral component|neutral component neutral component|bait|neutral component|bait|neutral component|neutral component|neutral component Hdac1 Rbbp7 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0018(two hybrid)|MI:0027(cosedimentation) 16615898,20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167137|UniProt_167117|UniProt_167133|UniProt_167125|BIOGRID_313843|UniProt_167129 neutral component|neutral component|neutral component|neutral component|prey|neutral component neutral component|neutral component|neutral component|neutral component|bait|neutral component L3mbtl2 Rbbp7 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22770845 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_328079|BIOGRID_328043 bait|bait prey|prey Rbbp7 Mta1 MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 16615898,18454139 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization) (biogrid)|(intact)|(intact) BIOGRID_314503|UniProt_167126|UniProt_167129 prey|neutral component|neutral component bait|neutral component|neutral component Gata1 Rbbp7 MI:0004(affinity chromatography technology) 15920471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_314927 bait prey Rbbp7 Eed MI:0027(cosedimentation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 16615898,20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_167137|UniProt_170405|UniProt_170404|UniProt_170406|BIOGRID_314292 neutral component|prey|prey|prey|prey neutral component|null|null|null|bait Hdac2 Rbbp7 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 16615898,18454139 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(biogrid)|(intact) UniProt_167137|UniProt_167133|BIOGRID_314489|UniProt_167129 neutral component|neutral component|bait|neutral component neutral component|neutral component|prey|neutral component Tet2 Rbbp7 MI:0004(affinity chromatography technology) 21490601 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_326079 bait prey Rbbp7 Nanog MI:0004(affinity chromatography technology) 18454139 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_314483 prey bait Sumo1 Rbbp7 MI:0004(affinity chromatography technology) 19189660 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322250 prey bait Tcf3 Rbbp7 MI:0004(affinity chromatography technology) 22354994 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_320651 bait prey

PPI - HINT Gene A Gene B PMID Method Quality HDAC1 RBBP7 20211142 0018 HT ZFPM1 RBBP7 15920470,15920470 0004,0071 LC YWHAE RBBP7 16615898 0027 LC RBBP7 PGLS 16615898 0027 LC ZFPM1 RBBP7 15920470,19654328,15920470 0004,0004,0071 LC SUV39H1 RBBP7 11788710 0096 LC TCF3 RBBP7 22354994 0004 LC GATA1 RBBP7 15920471 0004 LC POU5F1 RBBP7 20362541,18454139,22083510,20362541 0004,0004,0004,0007 LC SOX2 RBBP7 21532573,21532573 0007,0006 LC CENPC RBBP7 21274006 0096 LC L3MBTL2 RBBP7 22770845 0004 LC SUMO1 RBBP7 19189660 0004 LC HIST1H3A|HIST1H3G|HIST1H3H|HIST1H3I RBBP7 20211137 0096 LC HDAC2 RBBP7 18454139 0004 LC HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST2H3B|HIST2H3C1|HIST2H3C2 RBBP7 20211137 0096 LC H3F3A|H3F3B RBBP7 20211137 0096 LC TFCP2L1 RBBP7 20362541,20362541 0004,0007 LC TET1 RBBP7 21490601 0004 LC TET2 RBBP7 21490601 0004 LC RBBP7 EZH2 20064376,20064376,23624931 0004,0007,0096 LC RBBP7 SUZ12 22438827 0004 LC RBBP7 NANOG 18454139 0004 LC RBBP7 SALL4 20362541,20362541 0004,0007 LC RBBP7 MTA1 18454139 0004 LC RBBP7 EED 20064376,20064376 0007,0004 LC RBBP7 RNF2 17296600,17296600 0096,0004 LC RBBP7 CHAF1A 26365490 0004 LC RBBP7 MTA2 15920471,18454139 0004,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q60973 P59178 RBBP7 L3MBTL2 0.21 22770845 Q60973 P15806 RBBP7 TCF3 0.126 22354994 Q60973 O09106 RBBP7 HDAC1 0.183 20211142 Q60973 P63166 RBBP7 SUMO1 0.21 19189660 Q921E6 Q60973 EED RBBP7 0.332 20064376 Q60973 P62259 RBBP7 YWHAE 0.081 16615898 Q8K4B0 Q60973 MTA1 RBBP7 0.126 18454139 Q60973 O54864 RBBP7 SUV39H1 0.21 11788710 Q60973 O35615 RBBP7 ZFPM1 0.21 19654328 Q6AXH7 Q60973 EZH2 RBBP7 0.126 23624931 Q80U70 Q60973 SUZ12 RBBP7 0.21 22438827 Q80Z64 Q60973 NANOG RBBP7 0.126 18454139 Q9R190 Q60973 MTA2 RBBP7 0.309 15920471,18454139 Q9CQJ4 Q60973 RNF2 RBBP7 0.236 17296600 Q60973 Q3UNW5 RBBP7 TFCP2L1 0.236 20362541 Q60I23 Q60973 SOX2 RBBP7 0.236 21532573 Q8BX22 Q60973 SALL4 RBBP7 0.236 20362541 Q61188 Q60973 EZH2 RBBP7 0.332 20064376 Q60973 P20263 RBBP7 POU5F1 0.416 22083510,20362541,18454139 Q9CQ60 Q60973 PGLS RBBP7 0.081 16615898 Q9QWF0 Q60973 CHAF1A RBBP7 0.126 26365490 Q60973 P70288 RBBP7 HDAC2 0.126 18454139 Q60973 P17679 RBBP7 GATA1 0.21 15920471 Q60973 P49452 RBBP7 CENPC 0.126 21274006 Q60973 Q3URK3 RBBP7 TET1 0.21 21490601 Q60973 Q4JK59 RBBP7 TET2 0.21 21490601