PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Slc2a4 Tceb2 16396496 intact exp G G G Mapk3 Tceb2 19935650 mint,intact exp G G G G G G G Tceb2 Tceb1 11384984,10224134 biogrid exp G G G G G G G G Tceb2 Lrrc41 11384984 biogrid exp G G G G G G G G Nr3c1 Tceb2 16619302 intact exp G G G G G G G G Tceb2 Tceb3 19037258,10224134 biogrid,intact exp G G G G Homer2 Tceb2 ortho G G G Protein Wsb1, WD repeat and SOCS box-containing 1, WD repeat and SOCS box-containing 1, isoform CRA_b Tceb2 ortho G G G G G G G G Tceb2 Protein Rara, Retinoic acid receptor, alpha, Retinoic acid receptor, alpha, isoform CRA_b ortho G G Socs2 Tceb2 ortho Ywhae Tceb2 ortho G G G G G G G G Tceb2 Ywhah ortho G G G G G G G G Tceb2 Klhdc3 ortho G G G G G G G G Protein Adam19, RCG34059 Tceb2 ortho G G G G G G G G Socs3 Tceb2 ortho G G Tceb2 Vhl ortho G G G G G G G G Tceb2 Nrbp ortho G G G G G G G G Ppp5c Tceb2 ortho G G G G G G G Tceb2 Socs1 ortho Tceb2 Asb2 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P62870 P40337-3 pull down 9341197 direct interaction X 2 P62870 pull down 10224134 direct interaction X 2 P62870 Q5M9H1 biochemical 11384984 colocalization X 2 P62870 Q93034 affinity chromatography technology 19037258 physical association X 2 P62870 Q3TCH7 affinity chromatography technology 19037258 physical association X 2 P62870 affinity chromatography technology 19037258 physical association X 2 P62870 P83941 pull down 10224134 direct interaction X 2 P62870 P83941 biochemical 11384984 colocalization X 2 P62870 A0A024R475 affinity chromatography technology 19037258 physical association X 2 P62870 coimmunoprecipitation 12149480 association C 5 P62870 molecular sieving 10213691 association C 5 P62870 chromatography technology 10213691 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 coimmunoprecipitation 11384984 association C 5 P62870 reverse phase chromatography 8244996 association C 3 P62870 coimmunoprecipitation 15590664 association C 5 P62870 anti bait coimmunoprecipitation 16619302 association C 24 P62870 anti tag coimmunoprecipitation 19037258 association C 6 P62870 anti tag coimmunoprecipitation 19037258 association C 6 P62870 anti tag coimmunoprecipitation 19037258 association C 5 P62870 anti tag coimmunoprecipitation 19037258 association C 5 P62870 anti tag coimmunoprecipitation 19037258 association C 5 P62870 P21708 anti bait coimmunoprecipitation 19935650 association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Tceb2 Tceb1 MI:0096(pull down)|MI:0004(affinity chromatography technology) 10224134,11384984 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0403(colocalization)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_333565|BIOGRID_335132 bait|bait prey|prey Mapk3 Tceb2 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19935650 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0914(association)|MI:0914(association) MI:0471(mint)|(intact) MINT_71449|UniProt_185606 bait|bait prey|prey Tceb2 Tceb3 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,10224134,19037258 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact) UniProt_97849|MINT_73993|MINT_73995|UniProt_97850|UniProt_183304|UniProt_168995|UniProt_168996|UniProt_183303|MINT_43852|MINT_43854|BIOGRID_334443|BIOGRID_335133|UniProt_97852|UniProt_97851|MINT_73996|MINT_73997|MINT_43856|MINT_43855|UniProt_168997|UniProt_183306|UniProt_183305|UniProt_168998 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey bait|prey|bait|prey|prey|bait|prey|bait|prey|bait|bait|prey|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait Tceb2 Lrrc41 MI:0096(pull down) 11384984 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0403(colocalization) (biogrid) BIOGRID_333564 prey bait

PPI - HINT Gene A Gene B PMID Method Quality TCEB2 TCEB1 11384984 0401 LC TCEB2 LRRC41 11384984 0401 LC NR3C1 TCEB2 16619302 0006 LC SLC2A4 TCEB2 16396496 0007 LC MAPK3 TCEB2 19935650 0006 LC TCEB2 TCEB1 11384984,10224134 0401,0096 LC TCEB2 LRRC41 11384984 0401 LC TCEB2 TCEB3 19037258,19037258,10224134 0004,0007,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5M9H1 P62870 LRRC41 TCEB2 0.126 11384984 Q63187 P62870 TCEB3 TCEB2 0.21 19037258 P62870 P06536 TCEB2 NR3C1 0.21 16619302 Q93034 P62870 CUL5 TCEB2 0.376 19037258 Q3TCH7 P62870 CUL4A TCEB2 0.376 19037258 P83941 P62870 TCEB1 TCEB2 0.396 11384984,10224134 P62870 P40337 TCEB2 VHL 0.309 9341197 Q13618 P62870 CUL3 TCEB2 0.21 19037258 P62870 P21708 TCEB2 MAPK3 0.236 19935650 P62870 P19357 TCEB2 SLC2A4 0.126 16396496