PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Nfkbia Ikbkg i2d exp, ortho Sumo1 Ikbkg 21454665 biogrid exp, ortho Guanine nucleotide-binding protein subunit gamma Ikbkg ortho Ikbkg Erc1 ortho Frmd8 Ikbkg ortho Vim Ikbkg ortho Protein Trim5, Similar to 9230105E10Rik protein Ikbkg ortho Btrc Ikbkg ortho Atp5b Ikbkg ortho LOC100363786, Nrarp Ikbkg ortho Ikbkg Pycard ortho Zfand5 Ikbkg ortho Pleckstrin homology domain containing, family J member 1, Pleckstrin homology domain containing, family J member 1, isoform CRA_e, Protein Plekhj1 Ikbkg ortho Ikbke_predicted Ikbkg ortho Tarbp2 Ikbkg ortho Tnf Ikbkg ortho Map3k14_predicted Ikbkg ortho Ikbkg Bid ortho Psmb8 Ikbkg ortho Id1 Ikbkg ortho Ikbkg Tlr4 ortho Htt Ikbkg ortho Aip Ikbkg ortho Tpt1 Ikbkg ortho Protein Rptor Ikbkg ortho Rbm34 Ikbkg ortho Protein Tma16 Ikbkg ortho Protein Mars Ikbkg ortho Krt8 Ikbkg ortho Rbm8a Ikbkg ortho Usp10 Ikbkg ortho Ipo9_predicted Ikbkg ortho Myo1d Ikbkg ortho Met Ikbkg ortho RGD1560358_predicted Ikbkg ortho Flna_predicted Ikbkg ortho Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, Protein Nfkbie, Solute carrier family 35, member B2, isoform CRA_b Ikbkg ortho Eef1a1 Ikbkg ortho Hspa9 Ikbkg ortho Atp5o Ikbkg ortho Phf7 Ikbkg ortho Camk2d Ikbkg ortho Trim28 Ikbkg ortho Disks large-associated protein 3, RCG62665 Ikbkg ortho Gucy1a3 Ikbkg ortho Ikbkg Abca1 ortho Protein Msh3 Ikbkg ortho Ralbp1 Ikbkg ortho LIM and cysteine-rich domains 1, Protein Lmcd1 Ikbkg ortho Vars Ikbkg ortho Crebbp Ikbkg ortho Ikbkg Ikbkb ortho Cntn2 Ikbkg ortho Leucyl-tRNA synthetase, Protein Lars Ikbkg ortho Ikbkg Arpp19 ortho Eef1a2 Ikbkg ortho Map3k3_predicted Ikbkg ortho Tcp11 Ikbkg ortho Psma3 Ikbkg ortho Ikbkg Ssx2ip ortho Lrpprc Ikbkg ortho Tax1bp1 Ikbkg ortho Abl2_mapped Ikbkg ortho Ikbkg Myd88 ortho Protein Tnip2, TNFAIP3 interacting protein 2 Ikbkg ortho Senp6_predicted Ikbkg ortho Ror2_predicted Ikbkg ortho Ikbkg RelA ortho RGD1307915_predicted Ikbkg ortho Rps16 Ikbkg ortho Protein LOC690000 Ikbkg ortho Ikbkg Ddb1 ortho Ikbkg Myh10 ortho Nap1l5 Ikbkg ortho Gsk3b Ikbkg ortho Usp34 Ikbkg ortho Protein Txlna, Txlna protein Ikbkg ortho CD40 molecule, TNF receptor superfamily member 5, Protein Cd40, Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a Ikbkg ortho Protein Malt1 Ikbkg ortho Ino80e Ikbkg ortho Tcf3 Ikbkg ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ikbkg ortho Ikbkg Esyt1 ortho Stx11 Ikbkg ortho LOC100911235 Ikbkg ortho Sag Ikbkg ortho Hspd1 Ikbkg ortho Rpl23 Ikbkg ortho Parp1 Ikbkg ortho Cyclin-dependent kinase inhibitor 1A, Cyclin-dependent kinase inhibitor 1A (P21, Cip1), P21, P21 protein, Protein Cdkn1a Ikbkg ortho Protein Myo5c Ikbkg ortho Ripk1_predicted Ikbkg ortho Prkci Ikbkg ortho Serine/threonine-protein kinase Ikbkg ortho Protein Ppfia1 Ikbkg ortho Ube2d3 Ikbkg ortho Nfkb1 Ikbkg ortho Inha Ikbkg ortho Ikbkg Gemin2 ortho Mertk Ikbkg ortho Hpd Ikbkg ortho Notch1 Ikbkg ortho Ikbkg Lgals2 ortho Ikbkg Eaf2 ortho Leucine-zipper-like transcription regulator 1, Protein Lztr1, RCG36595 Ikbkg ortho Pck1 Ikbkg ortho Card15_predicted Ikbkg ortho Apba2bp_predicted Ikbkg ortho RT1-Ba Ikbkg ortho Protein Ripk2, RCG54865 Ikbkg ortho Arl6ip4 Ikbkg ortho Usp7 Ikbkg ortho Rpl11 Ikbkg ortho Ikbkg Src ortho Fyn Ikbkg ortho Lyn Ikbkg ortho Traf6 Ikbkg ortho Ppm1b Ikbkg ortho Aurka Ikbkg ortho Hspa4 Ikbkg ortho General transcription factor II E, polypeptide 1 (Alpha subunit), Protein Gtf2e1 Ikbkg ortho Ywhaz Ikbkg ortho Praf1_predicted Ikbkg ortho Grk4 Ikbkg ortho Jak2 Ikbkg ortho Protein Xpo5 Ikbkg ortho Ikbkg Mprip ortho Tab2 Ikbkg ortho Protein Parp14 Ikbkg ortho Protein Caap1, Uncharacterized protein Ikbkg ortho LOC683206 Ikbkg ortho Pfdn5_predicted Ikbkg ortho Luc7l2_predicted Ikbkg ortho Ikbkg Rps27 ortho Rnf31_predicted Ikbkg ortho Ikbkg Park2 ortho Prkce Ikbkg ortho Odam Ikbkg ortho Psmd13 Ikbkg ortho RGD1561140_predicted Ikbkg ortho Traf3_predicted Ikbkg ortho Cdc37 Ikbkg ortho Rpn1 Ikbkg ortho Canx Ikbkg ortho Lzic Ikbkg ortho Ikbkg F7 ortho Protein Trim41 Ikbkg ortho Lck Ikbkg ortho Pa2g4 Ikbkg ortho Cul1_predicted Ikbkg ortho Sgk1 Ikbkg ortho Tyrosine-protein kinase Ikbkg ortho CCR4-NOT transcription complex, subunit 7, Protein Cnot7, RCG59103 Ikbkg ortho Usp2 Ikbkg ortho Dbn1 Ikbkg ortho Timm50 Ikbkg ortho Vamp3 Ikbkg ortho Chromosome 6 open reading frame 4, isoform CRA_a, Protein Traf3ip2, Traf3 interacting protein 2 Ikbkg ortho RGD1308126_predicted Ikbkg ortho Cpne2 Ikbkg ortho Ikbkg Adap2 ortho Protein Tab1, RCG59826 Ikbkg ortho Il1b Ikbkg ortho Tsg101 Ikbkg ortho Cyld Ikbkg ortho Syt1 Ikbkg ortho Hpcal1 Ikbkg ortho Wdr5 Ikbkg ortho Trim23 Ikbkg ortho Bcl2-associated athanogene 3, Protein Bag3, RCG40209, isoform CRA_b Ikbkg ortho Dnajc8 Ikbkg ortho Arglu1 Ikbkg ortho Gins4 Ikbkg ortho Tubb5 Ikbkg ortho Plk1 Ikbkg ortho Ikbkg Senp2 ortho Protein Tnip1, RCG35421, isoform CRA_b Ikbkg ortho Leupaxin, Protein Lpxn Ikbkg ortho Anxa1 Ikbkg ortho Ppp2ca Ikbkg ortho Nmral1 Ikbkg ortho Sfxn1 Ikbkg ortho Cops3 Ikbkg ortho Protein Hbz, RCG35242 Ikbkg ortho Protein Atg16l1 Ikbkg ortho Ikbkg Casp8 ortho Kif5b Ikbkg ortho Tpx2_predicted Ikbkg ortho Nlrx1 Ikbkg ortho Prkcb Ikbkg ortho RGD1308297 Ikbkg ortho Myh9 Ikbkg ortho Map3k7 Ikbkg ortho RGD1304861 Ikbkg ortho Ikbkg Idh3a ortho Kcmf1 Ikbkg ortho Rnf7_predicted Ikbkg ortho Protein Pim2 Ikbkg ortho Akt1 Ikbkg ortho Protein Triobp Ikbkg ortho Hnrpu Ikbkg ortho Protein Golga3, RCG21481, isoform CRA_b Ikbkg ortho Rars Ikbkg ortho Trim13 Ikbkg ortho Protein Utp20 Ikbkg ortho Acbd6 Ikbkg ortho Hsp90b1 Ikbkg ortho Tubb4 Ikbkg ortho Trim31_predicted Ikbkg ortho Ikbkg Eif1a ortho LOC299827 Ikbkg ortho Atm_mapped Ikbkg ortho Polr2e Ikbkg ortho Ppp1cb Ikbkg ortho Ddx19b Ikbkg ortho Krt17 Ikbkg ortho Set Ikbkg ortho Gadd45gip1 Ikbkg ortho Protein Irak4 Ikbkg ortho Protein Atrip, RCG25767 Ikbkg ortho Ikbkg Sept9 ortho Ikbkg Avpi1 ortho DNA helicase Ikbkg ortho Ikbkg Bcl10 ortho Rhbdd3 Ikbkg ortho Hspa8 Ikbkg ortho Hspa5 Ikbkg ortho Rps5 Ikbkg ortho Baculoviral IAP repeat-containing 2, Protein Birc2 Ikbkg ortho Trim40 Ikbkg ortho Rhoa Ikbkg ortho Actg1 Ikbkg ortho Fos Ikbkg ortho Ikbkg Gadd45g ortho Clic1 Ikbkg ortho Jun Ikbkg ortho Rps14 Ikbkg ortho Ikbkg Sclt1 ortho Chuk_predicted Ikbkg ortho Protein Map3k2, RCG49590 Ikbkg ortho Ikbkg Ikbkg ortho Ntmt1 Ikbkg ortho Keap1 Ikbkg ortho RGD1561926_predicted Ikbkg ortho Interferon regulatory factor 7, Protein Irf7 Ikbkg ortho Myc Ikbkg ortho Ddit3 Ikbkg ortho Fasn Ikbkg ortho Sqstm1 Ikbkg ortho Ikbkg Ube2n ortho G protein-coupled receptor kinase interacting ArfGAP 2, Protein Git2 Ikbkg ortho Mtor Ikbkg ortho Calb1 Ikbkg ortho Dnaja3 Ikbkg ortho Glo1 Ikbkg ortho Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, isoform CRA_a, Protein Nfkb2 Ikbkg ortho Ubc Ikbkg ortho Irak1_predicted Ikbkg ortho Tubg1 Ikbkg ortho Ikbkg Sharpin ortho Ppp2r1b Ikbkg ortho Shootin-1 Ikbkg ortho Trim29_predicted Ikbkg ortho Tuba8 Ikbkg ortho Ribosomal protein S6 kinase Ikbkg ortho Arhgdia Ikbkg ortho Mapre1 Ikbkg ortho Nsfl1c Ikbkg ortho Ikbkg Nfkbib ortho Rbp1 Ikbkg ortho Hematopoietic cell specific Lyn substrate 1, Protein Hcls1, RCG52681 Ikbkg ortho Rps12 Ikbkg ortho Capza1 Ikbkg ortho Nfe2 Ikbkg ortho Rps3 Ikbkg ortho Hsp90aa1 Ikbkg ortho Rps27l Ikbkg ortho Ikbkg Flt4 ortho Bcl2 Ikbkg ortho Tuba1a Ikbkg ortho RGD1310803_predicted Ikbkg ortho Protein Tbc1d7 Ikbkg ortho Myo1c Ikbkg ortho Structural maintenance of chromosomes protein Ikbkg ortho Cdk2 Ikbkg ortho Hspa1l Ikbkg ortho E3 ubiquitin-protein ligase Ikbkg ortho Rnf4 Ikbkg ortho Trim14 Ikbkg ortho Hsp90ab1 Ikbkg ortho Mavs Ikbkg ortho Uba52 Ikbkg ortho Rps15a Ikbkg ortho Lymphotoxin B receptor, Lymphotoxin beta receptor (TNFR superfamily, member 3), Protein Ltbr Ikbkg ortho Cchcr1 Ikbkg ortho Protein Dapk1 Ikbkg ortho Tyro3 Ikbkg ortho Uso1 Ikbkg ortho Zc3h12a Ikbkg ortho Msh2 Ikbkg ortho Rps20 Ikbkg ortho Rbck1 Ikbkg ortho Nfkbiz_predicted Ikbkg ortho Gfap Ikbkg ortho Kansl2 Ikbkg ortho Traf2_predicted Ikbkg ortho Maml1_predicted Ikbkg ortho Casp6 Ikbkg ortho Protein Tceanc, RCG49713 Ikbkg ortho Egln3 Ikbkg ortho Protein Gcc1, RCG28300 Ikbkg ortho Rab11fip1 Ikbkg ortho Protein Taf7, RCG49239, TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa Ikbkg ortho DNA-directed RNA polymerase Ikbkg ortho Iars_predicted Ikbkg ortho Rbbp8 Ikbkg ortho Cse1l_predicted Ikbkg ortho Ikbkg Xpo1 ortho Rplp0 Ikbkg ortho Cltc Ikbkg ortho Id3 Ikbkg ortho Protein Tradd, TNFRSF1A-associated via death domain Ikbkg ortho Srpk1 Ikbkg ortho Polr2d_predicted Ikbkg ortho Ikbkg Tank ortho Birc3 Ikbkg ortho Ppp4c Ikbkg ortho Ikbkg fadd ortho Card10_predicted Ikbkg ortho Tnfrsf1a Ikbkg ortho Fgr Ikbkg ortho Ikbkg Dync1li1 ortho Aprt Ikbkg ortho Slc25a5 Ikbkg ortho Ipo7_predicted Ikbkg ortho Phosphoribosylglycinamide formyltransferase, isoform CRA_a, Protein Gart Ikbkg ortho Ikbkg Protein Stk25, Serine/threonine kinase 25, Serine/threonine kinase 25 (STE20 homolog, yeast), Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a ortho Protein Trpc4ap, Transient receptor potential cation channel, subfamily C, member 4 associated protein, Transient receptor potential cation channel, subfamily C, member 4 associated protein, isoform CRA_a Ikbkg ortho Ywhae Ikbkg ortho Myl6 Ikbkg ortho Gnb2l1 Ikbkg ortho Ret Ikbkg ortho FK506 binding protein 5, Protein Fkbp5, RCG60597 Ikbkg ortho Rpap3 Ikbkg ortho Krt18 Ikbkg ortho Ikbkg Prkcq ortho eplin Ikbkg ortho Coatomer subunit alpha Ikbkg ortho Dync1h1 Ikbkg ortho Mcm10_predicted Ikbkg ortho Pdcl Ikbkg ortho Ros1 Ikbkg ortho Rab11b Ikbkg ortho Ciapin1 Ikbkg ortho Ikbkg Hdlbp ortho Tnfrsf4 Ikbkg ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q63746 Q6TMG5 - 15946255 - X 2 Q6TMG5 Q5I0H3 affinity chromatography technology 21454665 physical association X 2 Q6TMG5 Q6TMG5 cosedimentation through density gradient 17419723 association Y 1 Q9QY78 Q6TMG5 cosedimentation through density gradient 17419723 association X 2 Q9QY78 Q6TMG5 coimmunoprecipitation 17419723 association X 2

PPI - HINT Gene A Gene B PMID Method Quality IKBKG IKBKG 17419723 0029 LC IKBKG IKBKB 17419723,17419723 0019,0029 LC SUMO1 IKBKG 21454665 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6TMG5 Q5I0H3 IKBKG SUMO1 0.21 21454665