PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus drk CG13358-RB 14605208 biogrid exp drk Myopic 22036573 biogrid exp G G G G G G G G G G drk RE50839p, Spliceosomal protein on the X 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G sty drk unassigned4 i2d,intact exp G G G G G G G G G Dab drk unassigned4,9671493 biogrid,intact exp G G G G G G G CG15071 drk 14605208 biogrid,intact exp G drk chico unassigned4 intact exp G G G G G G G G G G drk Spx i2d exp drk EG:34F3.10 14605208 i2d,mint,intact,dip exp drk Pi3K68D unassigned4 intact exp dl drk 14605208 biogrid,i2d,mint,intact,dip exp G G G G G G drk CG1806, isoform A, CG1806, isoform B, LP03706p 22036573 biogrid exp G G G drk CG4328-RA 14605208 biogrid,i2d,mint,intact exp G G drk Hexosaminidase 1, isoform A 22036573 biogrid exp G G G G G G G G G G drk dos 12128212 mint,intact exp G G G G G G G G G G drk Uncharacterized protein CG43867 14605208 biogrid exp G G drk Ptp36E 22036573 biogrid exp G G G G G G Egfr drk 21340027 biogrid exp G G G G G G drk blos2 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G drk LD04361p, Nek2 14605208 biogrid,i2d,mint,intact exp G drk CG5568, LD47944p 22036573 biogrid exp G drk ena 10220404 intact exp G G G G G G G G G G drk Probable prefoldin subunit 5 14605208 biogrid,i2d,mint,intact,dip exp, ortho G G G G G G G G G G drk cbl 10918586,21340027 biogrid exp, ortho G G G Src64B drk 14605208 biogrid,i2d,mint,intact,dip exp, ortho G G G G G G G drk drk 14605208 intact exp, ortho G G G G G G G G G G Sos drk 9178769,unassigned4,9671493 biogrid,i2d,intact exp, ortho G G G G G G G G G G csw drk unassigned4 intact exp, ortho G G G G G G G G G sev drk i2d exp, ortho G G G G shi drk 10918586 biogrid exp, ortho G G G G G G G G G Actn drk ortho G G G G G G G G G G drk RE62581p, RH06526p, Ribosomal protein L21, isoform A, Ribosomal protein L21, isoform B, Ribosomal protein L21, isoform C ortho G G G G G G G G G G drk CG10447-PA, Nuclear factor Y-box B, isoform B, RE06807p, RH50436p ortho G G G G G G G G G drk D-Importin 7/RanBP7, FI03666p, Moleskin ortho G G G G G G G G G G drk JIL-1 ortho G G G G G G RpII215 drk ortho G G G G G G G G G G drk CG8258, LD24495p ortho G G G G G G G G G G drk Arpc4 ortho G G G G G G G G G G drk Oscp ortho G G G G G G G G G G drk GH06496p, Synaptojanin, isoform A, Synaptojanin, isoform B, Synaptojanin, isoform C ortho G G G G G G G G G G drk Alphabet, isoform E, LD23542p ortho G G G G G G G G G G Fak56D drk ortho G G G G Drab11 drk ortho G G G G G G G G G G drk RpS11 ortho G G G G G G G G G G RpL40 drk ortho G G G G G G G G G G RpS13 drk ortho G G G G G G G G G G drk CG5522, isoform A, CG5522, isoform B, CG5522, isoform E ortho G G G G G G G G G Tm1 drk ortho G G G G G G G G G G Eps-15-RB drk ortho G G G G G G G G G G drk GMF ortho G G G G G G G G G G RpS9 drk ortho G G G G G G G G G G sca drk ortho G G drk Rpn6 ortho G G G G G G G G G G RpS25 drk ortho drk Tace ortho G G G G drk Pebble, isoform B ortho G G G G G G G G drk CG5966, isoform A, LD47264p ortho G G G G G G CanA1 drk ortho G G Chc drk ortho G G G G G G G G G G drk Arpc2 ortho G G G G G G G G G G drk eEF1delta ortho G G G G G G G G G G drk Gigas, isoform A ortho G G G G G G G G G G drk Cyfip ortho G G G G G G G G G G drk Myosin heavy chain-like, isoform B ortho G G G G drk flr ortho G G G G G G G G G Elongation factor Tu drk ortho G G G G G G G G G G drk IP03705p, Metabotropic GABA-B receptor subtype 1, isoform B, Metabotropic GABA-B receptor subtype 1, isoform C ortho G G T-cp1 drk ortho G G G G G G G G G G ps drk ortho G G G G G G G G drk RpS8 ortho G G G G G G G G G G drk Pxn ortho G G G G G G Hsc70-1 drk ortho G G RpL4 drk ortho G G G G G G G G G G drk Dreadlocks, isoform B, Dreadlocks, isoform C, Dreadlocks, isoform D, LD42588p ortho G G G G G G G G G RpS26 drk ortho G G G G G G G G G G Pen drk ortho G G 14-3-3zeta drk ortho G G G G G G G drk Beag, LD21347p ortho G G G G G G drk CG10652-PA, isoform A, RE25263p, Ribosomal protein L30, isoform B, Ribosomal protein L30, isoform E ortho G G G G G G G G G G drk TER94 ortho G G G G G G G G G G me31B drk ortho G G G G G G G G G G drk CG1909, isoform A, CG1909, isoform B, GH22690p ortho G G G CG8397 drk ortho G G G G G G G G G G drk Vav ortho G G G G G G G G RpS27A drk ortho G G G G G G G G G G Short stop, isoform H drk ortho G G G G G G G G G G drk Cortactin, isoform A, Cortactin, isoform B, Cortactin, isoform C, Cortactin, isoform D, LD29964p ortho G G G G G G G G G G Pka-R1 drk ortho G G G G G G G G G drk Rbp6 ortho G G G Klp54D-RA drk ortho G G G G G drk Fhos ortho G G G G G G G G drk dnc ortho G G G G G G G G G drk rst ortho G G G G Abl drk ortho G G G G G G G G G G drk Adherens junction protein p120 ortho G G G G G G G G G G Actin related complex p41 subunit, Actin-related protein 2/3 complex, subunit 1, isoform A, Actin-related protein 2/3 complex, subunit 1, isoform B, SD06579p drk ortho G G G G G G G G G G drk Ribosomal protein S30, isoform A, Ribosomal protein S30, isoform B, Ribosomal protein S30, isoform C ortho G G G G G G G G G G drk GM12270p, T-complex chaperonin 5, isoform A ortho G G G G G G G G G G drk BcDNA.GH08312 ortho G G G G G G G G G G Dhc64C drk ortho G G G G G G G G G G drk btl ortho G heph drk ortho G G G G G G G drk Protein odr-4 homolog ortho G G G G G G G G G G Btk29A drk ortho G G G G drk 40S ribosomal protein S27 ortho G G G G G G G G G G IGF-II mRNA-binding protein, isoform L, IGF-II mRNA-binding protein, isoform M drk ortho G G G G G G G G G drk fliI ortho G G G G G G G G G drk Trn-RA ortho G G G G G G G G G G RpL13 drk ortho G G G G G G G G G G drk Mfe2 ortho G G G G G G G G G G drk botv ortho G G G G G G G G G betaCop drk ortho G G G G G G G G G G SdhB drk ortho G G G G G G G G G G drk Levy, isoform A, Levy, isoform B, RH03295p ortho G G G G G G G G G G InR drk ortho G G G G G G G G G drk plexB ortho G G G G G G G G G G Gl drk ortho G G G G G G G G G G drk l(3)72Ab ortho G G G G G G G G G G 5-aminolevulinate synthase drk ortho G G G G G G G G G G Arp2 drk ortho G G G G G G G G G G BM-40, BM-40-SPARC, isoform A, BM-40-SPARC, isoform B, MIP10412p1 drk ortho G G G G G G G G G G drk Dihydrolipoyl dehydrogenase ortho G G G G G G G G G G drk NELF-B ortho G G G G G G G G jar drk ortho G G G G G G G G G G drk Immune response deficient 1, isoform A ortho G G G G G G G G G Cctgamma drk ortho G G G G G G G G G G drk mew ortho G G G G G G G G drk AP complex subunit beta ortho G G G G G G G G G G drk l(1)G0255-RA ortho G G G G G G G G G G drk RpS16 ortho G G G G G G G G G G CG10663, isoform B, CG10663, isoform D drk ortho drk Cullin 3, isoform F, FI19425p1 ortho G G G G G G G G G G drk Probable cysteine desulfurase, mitochondrial ortho G G G G G G G G G G Cholecystokinin-like receptor at 17D1 drk ortho drk RE52028p, Sorting nexin 3, isoform A, Sorting nexin 3, isoform B ortho G G G G G G G G G G drk LD41216p, SMU1 ortholog, isoform A, SMU1 ortholog, isoform B, SMU1 ortholog, isoform C ortho G G G G G G G Cyp1 drk ortho G G G G G G G G G G drk Non-specific serine/threonine protein kinase ortho G G G G G G G G G G alpha-Spec drk ortho G G G G G G G G G G RpL7 drk ortho G G G G G G G G G G drk CG5734-PA, LD15323p ortho G G G G G G G G G G drk RuvB-like helicase 1 ortho G G G G G G G G G G CG1513-RA drk ortho G G G G G G G G G G drk Octbeta2R ortho Adaptor protein complex 2, mu subunit, isoform A, Adaptor protein complex 2, mu subunit, isoform B, Adaptor protein complex 2, mu subunit, isoform C, Clathrin-associated adaptor complex AP-2 medium chain, Clathrin-associated protein, SD05403p drk ortho G G G G G G G G G G tum-RA drk ortho G G drk Arpc3A-RC ortho G G G drk csul ortho G G G G pod1-RC drk ortho G G G G G G G G G G drk Pabp2 ortho G G G G G G G G G G drk Mer ortho G G G G G G G G G drk Presequence protease, mitochondrial ortho G G G G G G G G G G drk CSN5 ortho G G G G G G G G G G drk CG5554, isoform A, GH07506p ortho G G G G G G G G G G EcR drk ortho G G G G G drk RpS28b ortho G G G G G G G G G G drk zip ortho G G G G G G G G G G EG:86E4.5 drk ortho G G G G G G G G G G drk sesB ortho G G G G G G G G G G spg drk ortho G G G G EF2 drk ortho G G G G G G G G G G sgl drk ortho G G G G G G G G G drk NimA-like kinase ortho drk Probable uridine-cytidine kinase, UCK ortho G G G G G G G G G drk AP-2-sigma ortho G G G G G G G G G G drk Ef1gamma ortho G G G G G G G G G G drk AAA family protein Bor, Belphegor, isoform A, Belphegor, isoform B ortho G G G G G G G G G G PyK drk ortho G G G G G G G G G G drk CG6543, isoform A, CG6543, isoform B, LD24265p ortho G G G G G G G G G G drk RhoGAPp190 ortho G G G G G G G G drk Cas ortho G G G G G G G G G G mle drk ortho G G G G G G G drk CG6287-PA, GH03305p ortho G G G G G G G G G G RpS18 drk ortho G G G G G G G G G G drk Hel25E ortho G G G G G G G G G G drk ALG-2 interacting protein X, LD25543p ortho G G G G G G G G G G drk CG4390, isoform B ortho G G G G G G G G G G RpL23 drk ortho G G G G G G G G G G drk RIC (Ras which interacts with Calmodulin), Ras-related protein interacting with calmodulin, isoform A, Ras-related protein interacting with calmodulin, isoform B ortho G G G G G G G G G G drk G patch domain and ankyrin repeat-containing protein 1 homolog ortho G G G G G G G drk RE28824p, Ribosomal protein L12, isoform A, Ribosomal protein L12, isoform B, Ribosomal protein L12, isoform C ortho G G G G G G G G G G beta-Spec drk ortho G G G G G G G G G G drk RpS19b ortho G drk CG4538-RA ortho G G G G G G G G G G RpL18A drk ortho G G G G G G G G G G 128up drk ortho G G G G G G G G G G drk Eukaryotic initiation factor 4A-III, eIF-4A-III, eIF4A-III ortho G G G G G G G G G G drk Mob3 ortho G G G G G G G G G G drk Hrs ortho G G G G G G G G G G drk CG9135 protein, CG9135, isoform A, CG9135, isoform B, CG9135, isoform C, CG9135, isoform D, CG9135-PA, LD39815p ortho G G G G G drk 26S proteasome regulatory complex subunit p48B, Regulatory particle triple-A ATPase 1, SD07148p ortho G G G G G G G G G G RpS20 drk ortho G G G G G G G G G G Vha26 drk ortho G G G G G G G G G G His3, His3:CG31613, His3:CG33803, His3:CG33806, His3:CG33809, His3:CG33812, His3:CG33815, His3:CG33818, His3:CG33821, His3:CG33824, His3:CG33827, His3:CG33830, His3:CG33833, His3:CG33836, His3:CG33839, His3:CG33842, His3:CG33845, His3:CG33848, His3:CG33851, His3:CG33854, His3:CG33857, His3:CG33860, His3:CG33863, His3:CG33866 drk ortho drk CG10077, isoform D, CG10077-PA, isoform A, GH10652p ortho G G G G G G G G G G CaMKII drk ortho G G G drk Brahma associated protein 55kD, LD29458p ortho G G G G G G G G G G Ubi-p63E drk ortho G G G G G G G G G G drk Myosin 95E, isoform E ortho G G G G G G G G usp drk ortho G G G G G G G G G Hsp83 drk ortho G G G G G G G G G G drk RpS5a ortho G G G G G G G G G G P-element somatic inhibitor, isoform C drk ortho G G G G G G G G drk Pcmt ortho G G G G G G G G G G drk GstZ1 ortho G G G G G G G drk CG9267-RA ortho G G G G G G G G G G MTA1-like drk ortho G G G G G G G G G Hsc70-5 drk ortho G G G G G G G G G G drk Phosphoinositide phospholipase C ortho G G G G G G G G G drk Blue cheese ortho G G G G G drk MED14 ortho G G G G G G G G G G DNApol-delta drk ortho G G G G RpL27A drk ortho G G G G G G G G G G drk bel ortho G G G G G G G G G G drk PPP5 ortho G G G G G G G G G G drk mbt ortho G G G G G G G G G G drk Pdk1 ortho G G G G G G G G G drk pex13 ortho G G G G G G G G G G r drk ortho G G dia drk ortho G G G G G G G G blw drk ortho G G G G G G G G G G drk Actin-related protein 2/3 complex subunit 5 ortho G G G G G G G G G G ArfGAP with SH3 domain, ankyrin repeat and PH domain, isoform B, RH04774p drk ortho G G G G G G G G G drk Tumor suppressor protein 101, Tumor susceptibility gene 101 ortholog ortho G G G G G G G G G G RpI135 drk ortho G G G G drk GH13256p, Thiolase ortho G G G G G G G G G G drk Protein UBASH3A homolog ortho G G G G G Receptor protein-tyrosine kinase drk ortho G G G G G G G G G Mlc-c drk ortho G G G G G G G G G G Apoptosis-linked gene-2 drk ortho cpb drk ortho G G G G G G G G G G drk T-complex protein 1 subunit delta ortho G G G G G G G G G G drk DCN1-like protein ortho G G G G G G G G G G drk LD40728p, RluA-2, isoform A, RluA-2, isoform D ortho G G G G G drk CG33172-RA ortho G drk CG6846-PA, RE17611p, Ribosomal protein L26, isoform B ortho G G G G G G G G G G 14-3-3epsilon drk ortho G G G G G G G G G G drk cher ortho G G G G G G G mbc drk ortho G G G G G G G G G G Happyhour, isoform A drk ortho G G G G G G G G G G Gad1 drk ortho G G G flw drk ortho G G G G G G G G G G drk Aspartyl-tRNA synthetase, isoform A, Aspartyl-tRNA synthetase, isoform B, Aspartyl-tRNA synthetase, isoform C, GM14334p ortho G G G G G G G G G G mtSSB drk ortho G G G G G G G G G Medea drk ortho G G G G G G G G G Cdc42 drk ortho G G G G G G G G G G Hsp60 drk ortho G G G G G G G G G G RpL3 drk ortho G G G G G G G G G G drk Lethal (2) 09851, isoform A, Lethal (2) 09851, isoform B, RE17371p, RE55020p ortho G G G G G G G G G G RpS3 drk ortho drk Bap60 ortho G G G G G G G G G G drk 60S ribosomal protein L27 ortho G G G G G G G G G G drk 26S proteasome regulatory complex subunit p39A, LD17530p, Regulatory particle non-ATPase 9, isoform A, Regulatory particle non-ATPase 9, isoform B ortho G G G G G G G G G G drk CG4164, LD30318p ortho G G G G G G G G G G drk RpL18 ortho G G G G G G G G G G drk CG9090-RA ortho G G G G G G Arp3 drk ortho G G G G G G G G G G drk betaTub56D ortho G G G G G G G G G G Gs1 drk ortho G G G G G G G G G G AP-2alpha drk ortho G G G G G G G G G drk LD47396p, Tcp-1eta ortho G G G G G G G G G G Uch drk ortho G G G G G G G G G G drk Myo61F ortho G G G G G G Hem drk ortho G G G G G G G G G G drk Dop1R2 ortho G G Act5C drk ortho G G G G G G G G G G AnxB10 drk ortho G G G G G G G G G G drk CG3018-PA, isoform A, Dorsal interacting protein 4, GM08377p, Lesswright, isoform A, Lesswright, isoform C, Lesswright, isoform D, RE25737p, Ubiquitin-conjugating enzyme, Ubiquitin-conjugating enzyme 9, Ubiquitin-conjugating enzyme 9 homolog ortho G G G G G G G G G G drk eIF-3p66 ortho G G G G G G G G G G drk RE17737p, RH44960p, Ribosomal protein L35A ortho G G G G G G G G G G drk RpS23 ortho G G G G G G G G G G drk Ptpmeg-RC ortho G G G G G G G G G G drk DSH3PX1 ortho G G G G G G G G G G drk CG12099, isoform A, CG12099, isoform B, LD09551p ortho G G G G G G G G G G drk RuvB-like helicase 2 ortho G G G G G G G G G G sqh drk ortho G G G G G G G G G G Transcription factor AP-2, isoform D drk ortho G G drk MED28 ortho G G G G G G G G htl drk ortho G G G G G G drk CG11807, isoform A, CG11807, isoform B, CG11807, isoform C, SD03973p ortho G G G G G G G G G G drk l(2)tid ortho G G G G G G G G G G Act79B drk ortho G G G Not1 drk ortho G G G G G G G G G drk Irbp ortho G G G drk Crk ortho G G G G G G G G G G drk CG2224-RA ortho G G G G G G drk CG5044-RB ortho G G G G G G G G G G drk RpL5 ortho G G G G G G G G G G drk Multifunctional protein ADE2 ortho G G G G G G G G G Nup98-RA drk ortho G G G G G G G G drk Aats-arg ortho G G G G G G G G G G Taf1 drk ortho G G G G G G G G G G drk Clc ortho G G G G G G G G G G drk Dmn ortho G G G G G G G G G G RpL14 drk ortho G G G G G G G G G G drk sog ortho G G drk Protein purity of essence ortho G G G G G G G G G G drk sfl ortho G G G G G drk l(2)37Cg ortho G G G G G G G G G G drk Glutamate [NMDA] receptor subunit 1, DNMDAR-I, dNR1 ortho G G Eno drk ortho G G G G G G G G G G His4, His4r, His4:CG31611, His4:CG33869, His4:CG33871, His4:CG33873, His4:CG33875, His4:CG33877, His4:CG33879, His4:CG33881, His4:CG33883, His4:CG33885, His4:CG33887, His4:CG33889, His4:CG33891, His4:CG33893, His4:CG33895, His4:CG33897, His4:CG33899, His4:CG33901, His4:CG33903, His4:CG33905, His4:CG33907, His4:CG33909 drk ortho drk Rpn11 ortho G G G G G G G G G G drk BcDNA.LD08534 ortho G G G G G G G drk Shc-RA ortho G G G G G G G G G G alc-RA drk ortho ATPsyn-beta drk ortho G G G G G G G G G G drk Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G slo drk ortho G G G G drk Brahma associated protein 155 kDa, LD22973p, Moira, isoform A ortho G G G G G G G G G G drk GH24511p, Ubiquitin activating enzyme 1, isoform A ortho G G G G G G G G G G drk CG7033, SD02216p ortho G G G G G G G G G G drk Dihydropteridine reductase, Dihydropteridine reductase, isoform A, Dihydropteridine reductase, isoform B, RE58329p ortho G G G G G G G G G Vacuolar protein sorting 13, isoform A, Vacuolar protein sorting 13, isoform B drk ortho G G G G G G G G G G drk Drosha, LD20030p, Ribonuclease ortho G G G G G G G Hsc70-3 drk ortho G G G G G G G G G G drk SmD2 ortho G G G G G G G G G G Pkc53E drk ortho G G G G G msps drk ortho G G G G G G G G G G drk RpL24 ortho G G G G G G G G G G drk CG9547, GH06693p ortho G G G G G G G G G drk anon-35F/36A ortho G G G G G G G G G G rl drk ortho G G G G G G G G G G drk CG9209-PA, isoform A, GH13542p, RasGap protein, Vacuolar peduncle, isoform B, Vacuolar peduncle, isoform C, Vacuolar peduncle, isoform D, Vacuolar peduncle, isoform E, Vacuolar peduncle, isoform F ortho G G G G G G G G G drk RhoGAP92B ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q08012 Q9W424 - 14605208 - X 2 Q08012 Q9XZT0 - 14605208 - X 2 Q08012 Q9VTE0 - 14605208 - X 2 Q08012 - 14605208 - X 2 Q08012 E1JIT4 - 14605208 - X 2 Q08012 - 7781603 - X 2 Q08012 P26675 - 8462098 - X 2 Q08012 P26675 - 8462098 - X 2 Q08012 P26675 - 7781603 - X 2 O44783 Q08012 - 10089881 - X 2 A1ZBC3 Q08012 - 14605208 - X 2 Q08012 - 11053437 - X 2 Q08012 C7LA93 - 14605208 - X 2 Q08012 M9MSK3 - 14605208 - X 2 Q08012 - 14605208 - X 2 Q9W3N8 Q08012 - 14605208 - X 2 Q08012 O46034 affinity chromatography technology 21340027 physical association X 2 Q08012 P04412-2 affinity chromatography technology 21340027 physical association X 2 Q08012 O46034 pull down 10918586 direct interaction X 2 Q08012 O46034 pull down 10918586 direct interaction X 2 Q08012 P26675 affinity chromatography technology 9671493 physical association X 2 Q08012 Q9XZT0 two hybrid 14605208 direct interaction X 2 Q08012 Q9VTE0 two hybrid 14605208 direct interaction X 2 Q08012 Q9W424 two hybrid 14605208 direct interaction X 2 Q08012 E1JHK3 two hybrid 14605208 direct interaction X 2 Q08012 E1JIT4 two hybrid 14605208 direct interaction X 2 Q08012 two hybrid 14605208 direct interaction X 2 Q08012 affinity chromatography technology 22036573 physical association X 2 Q08012 Q0E8H9 affinity chromatography technology 22036573 physical association X 2 A1ZBC3 Q08012 two hybrid 14605208 direct interaction X 2 Q08012 A4V4J0 pull down 10918586 direct interaction X 2 Q08012 E1JI13 affinity chromatography technology 9671493 physical association X 2 Q08012 E1JI13 pull down 9671493 direct interaction X 2 Q08012 E1JI13 affinity chromatography technology 9671493 physical association X 2 Q08012 Q9VTW3 two hybrid 14605208 direct interaction X 2 Q08012 M9MSK3 two hybrid 14605208 direct interaction X 2 Q08012 Q9V3V3 affinity chromatography technology 22036573 physical association X 2 Q08012 Q9VRQ4 affinity chromatography technology 22036573 physical association X 2 Q9W3N8 Q08012 two hybrid 14605208 direct interaction X 2 Q9VUH6 Q08012 affinity chromatography technology 22036573 physical association X 2 Q08012 Q9XZT0 two hybrid 14605208 physical association X 2 Q08012 Q9VTE0 two hybrid 14605208 physical association X 2 Q08012 Q9W424 two hybrid 14605208 physical association X 2 Q08012 E1JIT4 two hybrid 14605208 physical association X 2 A1ZBC3 Q08012 two hybrid 14605208 physical association X 2 Q08012 two hybrid 14605208 physical association X 2 Q08012 Q9VTW3 two hybrid 14605208 physical association X 2 Q08012 C7LA93 two hybrid 14605208 physical association X 2 Q08012 M9MSK3 two hybrid 14605208 physical association X 2 Q9W3N8 Q08012 two hybrid 14605208 physical association X 2 P29349 Q08012 experimental interaction detection - physical association X 2 Q08012 Q8T4F7 pull down 10220404 physical association X 2 Q08012 Q9XZT0 two hybrid 14605208 physical association X 2 Q08012 Q9VTE0 two hybrid 14605208 physical association X 2 Q08012 Q9W424 two hybrid 14605208 physical association X 2 Q08012 E1JHK3 two hybrid 14605208 physical association X 2 Q08012 E1JIT4 two hybrid 14605208 physical association X 2 Q08012 P26675 pull down 9178769 direct interaction X 2 Q08012 M9PCQ8 experimental interaction detection - physical association X 2 Q08012 P98081 experimental interaction detection - physical association X 2 Q08012 P26675 experimental interaction detection - physical association X 2 O44783 Q08012 experimental interaction detection - physical association X 2 L7RZC6 Q08012 pull down 12128212 physical association X 2 L7RZC6 Q08012 pull down 12128212 physical association X 2 L7RZC6 Q08012 pull down 12128212 physical association X 2 L7RZC6 Q08012 pull down 12128212 physical association X 2 L7RZC6 Q08012 anti tag coimmunoprecipitation 12128212 physical association X 2 A1ZBC3 Q08012 two hybrid 14605208 physical association X 2 Q08012 Q9VTW3 two hybrid 14605208 physical association X 2 Q08012 M9MSK3 two hybrid 14605208 physical association X 2 Q08012 P22681 pull down 9178769 direct interaction X 2 Q9W3N8 Q08012 two hybrid 14605208 physical association X 2 Q7JNX6 Q08012 experimental interaction detection - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B drk CG1806 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69574 bait prey drk dos MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 12128212 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_19242|UniProt_39349|UniProt_39348|UniProt_39347|MINT_19246|MINT_19245|MINT_19244|MINT_19243|UniProt_39351|UniProt_39350 bait|bait|bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey|prey|prey csw drk MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45548 unspecified role unspecified role Dab drk MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0045(experimental interaction detection)|MI:0004(affinity chromatography technology) 9671493 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(biogrid) BIOGRID_60878|BIOGRID_60876|UniProt_45587|BIOGRID_60874 prey|prey|unspecified role|bait bait|bait|unspecified role|prey drk Hexo1 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71544 bait prey sty drk MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45648 unspecified role unspecified role Egfr drk MI:0004(affinity chromatography technology) 21340027 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_75353 bait prey drk EG:34F3.10 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact)|MI:0471(mint) DIP_12882|UniProt_52206|MINT_27871 -|bait|bait -|prey|prey drk chico MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45496 unspecified role unspecified role drk Pi3K68D MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45650 unspecified role unspecified role drk CG4328-RA MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_23323 - - shi drk MI:0096(pull down) 10918586 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_77008 prey bait drk CG15071 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip) UniProt_59634|BIOGRID_40716|DIP_15664 bait|prey|- prey|bait|- Sos drk MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0045(experimental interaction detection) 9178769,9671493 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(intact) UniProt_45237|UniProt_134406|BIOGRID_60873|UniProt_45649 prey|prey|bait|unspecified role bait|bait|prey|unspecified role drk Pez MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71433 bait prey Cbl drk MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 10918586,21340027 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_77004|BIOGRID_75351|BIOGRID_77006 bait|bait|prey prey|prey|bait drk ena MI:0018(two hybrid)|MI:0018(two hybrid) 10220404 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_160413|UniProt_39224 bait|bait prey|prey drk Q9V8L1 MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_8003 bait prey drk CG7048 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_24772|MINT_16460|BIOGRID_46830|UniProt_62669 -|bait|bait|bait -|prey|prey|prey dl drk MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_24771|MINT_19080|BIOGRID_46829|UniProt_62668 -|null|prey|null -|prey|bait|prey drk CG4328-RA MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|(biogrid) UniProt_50516|MINT_15095|BIOGRID_45781 bait|bait|prey prey|prey|bait drk mop MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72165 bait prey drk CG14632 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|(biogrid) UniProt_48205|MINT_29735|BIOGRID_31650 bait|bait|prey prey|prey|bait drk blos2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_14145|MINT_29085|BIOGRID_39746|UniProt_47463 -|prey|prey|prey -|bait|bait|bait drk CG14632 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_14915 - - Src64B drk MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0465(dip)|MI:0471(mint)|(biogrid) UniProt_62670|DIP_24773|MINT_16461|BIOGRID_46831 bait|-|bait|prey prey|-|prey|bait drk Nek2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|MI:0471(mint) BIOGRID_32224|UniProt_55578|DIP_17626|MINT_9857 prey|bait|-|bait bait|prey|-|prey drk Spx MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0465(dip)|(intact) BIOGRID_45262|MINT_14445|DIP_22645|UniProt_49848 prey|prey|-|prey bait|bait|-|bait CG14818 drk MI:0004(affinity chromatography technology) 21825077 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_611649 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q08012 P22681 DRK CBL 0.309 9178769 Q08012 O44783 DRK STY 0.126 unassigned4 Q7JNX6 Q08012 PI3K68D DRK 0.126 unassigned4 Q08012 P00528 DRK SRC64B 0.354 14605208 Q08012 P04412 DRK EGFR 0.21 21340027 Q9XZT0 Q08012 EG:34F3.10 DRK 0.21 14605208 Q9VTW3 Q08012 CG4328-RA DRK 0.21 14605208 Q9W3N8 Q08012 NEK2 DRK 0.21 14605208 Q9W424 Q08012 SPX DRK 0.21 14605208 Q08012 A1ZBC3 DRK A1ZBC3 0.21 14605208 Q08012 P26675 DRK SOS 0.523 9671493,unassigned4,9178769 Q9VTE0 Q08012 BLOS2 DRK 0.332 14605208 Q9VZZ9 Q08012 DOS DRK 0.376 12128212 Q9W5D0 Q08012 Q9W5D0 DRK 0.183 14605208 Q08012 P98081 DRK DAB 0.623 9671493,unassigned4 Q08012 A0A1B2 DRK A0A1B2 0.033 14605208 Q08012 P15330 DRK DL 0.354 14605208 Q08012 P27619 DRK SHI 0.309 10918586 Q08012 P29349 DRK CSW 0.126 unassigned4 Q8T4F7 Q08012 ENA DRK 0.21 10220404 Q9VCZ8 Q08012 Q9VCZ8 DRK 0.354 14605208 Q9XTN2 Q08012 CHICO DRK 0.126 unassigned4