iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118558

UUCD1 version

UUC-TaR-00254

Ensembl Protein ID

ENSTRUP00000012903.1

UniProt Accession

H2SKH0; H2SKH0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

cul1b; cul1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005377.1	ENSTRUT00000012964.1	ENSTRUP00000012903.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.10e-223	743.2	24	659

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk...........................vgaklYkklkevleefikqvkkkveesed 62
           lr++++++++++s+ k++y+elyt+vyn+c+s                            vg +lYk+lke+l+++++ + k+ e+ +d
   Q: 24   LRAGIQQVYTRQSMaKSRYMELYTHVYNYCTSVhqssqgrgsappakpskksstpggaqfVGLELYKRLKEFLKNYLTSLLKDGEDLMD 112
           7899***************************9999****************************************************** PP
   S: 63   eqlLktynreWekfreqlkvlrkifayldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrll 146
           e +Lk+y+++We++r ++kvl+ i+ayl+r++v++     +k ++e+++Lal +wr++++++++k++++++lklie+eR+ge++++rl+
   Q: 113  ECVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRecdegRKGIYEIYSLALVTWRECLFRPLNKQVTNAVLKLIERERNGETINTRLI 201
           ***********************************999999999********************************************* PP
   S: 147  sgvveslveLslnk.........laiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlev 226
           sgvv+s+veL+ln+         l++yke FE +fl+ t++fy++es+eflq+n v+eY+kk+earl ee++r++ yl+est+++L+++
   Q: 202  SGVVQSYVELGLNEedafakgptLSVYKEYFECQFLTDTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARK 290
           ***************************************************************************************** PP
   S: 227  vekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqk 313
           +e++li+khle +++e+++ll+ +k+edl+rmy+L+sr+++gl el k le+hi++qg+aa++   e++ +dpk yV++ l++++k++ 
   Q: 291  CEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRITDGLGELKKLLETHIHNQGLAAIEkcGEAALNDPKVYVQTTLDVHKKYNA 379
           ***************************************************************9999999******************* PP
   S: 314  lvseaFnndakFlkaldkafetfvnknsvlka....akspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkk 398
           lv++aFnnda F+ aldka+ +f+n+n+v+++    +kspEllAry+D+lL+kssk+++e+ele +l++v++vfkyi++kdvF+k+Y+k
   Q: 380  LVMSAFNNDAGFVAALDKACGRFINNNAVTRMaqssSKSPELLARYCDSLLKKSSKNPEEAELE-TLNQVMVVFKYIEDKDVFQKFYAK 467
           **************************************************************98.69********************** PP
   S: 399  hLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsL 487
           +LakRL++++sas++aE+s+i+kLk++cg+e+tskL+rMfqd+ vS+dln+qFk++ +n+ e  ++++s++vLs+g+Wp++++   ++L
   Q: 468  MLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNS-EPLDLDFSIQVLSSGSWPFQQSCT-FAL 554
           ******************************************************777776.99******************7755.*** PP
   S: 488  PaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLv 576
           P+ele+++++f++fY ++hsgRkL+W+++l+++el ++++k++y+lq+stfQma+LL++n++++++v++l+++t+++++ L ++lq L+
   Q: 555  PSELERSYQRFTAFYASRHSGRKLTWLYHLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDSYTVQQLTDSTQIKTDILIQVLQILL 643
           ***************************************************************************************** PP
   S: 577  sskkqvlkkepeskeiee 594
           +sk  +l +e+e+++++e
   Q: 644  KSK--LLVMEDENANVDE 659
           **9..9999999888776 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSSNRTQNPH GLRQIGLDQI WDDLRAGIQQ VYTRQSMAKS RYMELYTHVY NYCTSVHQSS 60
QGRGSAPPAK PSKKSSTPGG AQFVGLELYK RLKEFLKNYL TSLLKDGEDL MDECVLKFYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTCCA ACAGGACCCA GAACCCTCAT GGACTCAGAC AGATAGGTCT GGACCAGATA 60
TGGGACGACC TGCGGGCTGG TATCCAGCAG GTGTACACGC GGCAAAGCAT GGCCAAGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	94.85	0.00e+00	1502.00
IUUC-Apl-003503	Anas platyrhynchos	94.91	0.00e+00	1214.00
IUUC-Aca-005030	Anolis carolinensis	83.15	0.00e+00	1171.00
IUUC-Ago-007977	Ashbya gossypii	32.64	1.00e-118	420.00
IUUC-Acl-008190	Aspergillus clavatus	48.45	0.00e+00	658.00
IUUC-Afl-008542	Aspergillus flavus	48.32	1.00e-152	533.00
IUUC-Afu-009007	Aspergillus fumigatus	48.36	0.00e+00	639.00
IUUC-Ani-009290	Aspergillus nidulans	46.51	0.00e+00	679.00
IUUC-Ang-009600	Aspergillus niger	48.27	0.00e+00	657.00
IUUC-Aor-009978	Aspergillus oryzae	47.21	4.00e-171	595.00
IUUC-Ate-010584	Aspergillus terreus	47.84	0.00e+00	673.00
IUUC-Ame-011861	Astyanax mexicanus	94.94	0.00e+00	1458.00
IUUC-Bgr-012209	Blumeria graminis	47.95	0.00e+00	647.00
IUUC-Bta-012878	Bos taurus	94.97	0.00e+00	1507.00
IUUC-Bci-013941	Botrytis cinerea	48.20	0.00e+00	708.00
IUUC-Cel-018294	Caenorhabditis elegans	46.41	0.00e+00	692.00
IUUC-Cja-018965	Callithrix jacchus	91.38	0.00e+00	1435.00
IUUC-Cfa-020671	Canis familiaris	94.97	0.00e+00	1507.00
IUUC-Cpo-021762	Cavia porcellus	94.85	0.00e+00	1507.00
IUUC-Csa-023873	Chlorocebus sabaeus	94.97	0.00e+00	1507.00
IUUC-Cho-024978	Choloepus hoffmanni	96.00	7.00e-112	397.00
IUUC-Cin-025547	Ciona intestinalis	72.54	0.00e+00	1112.00
IUUC-Csv-026083	Ciona savignyi	72.10	0.00e+00	1155.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	48.04	0.00e+00	674.00
IUUC-Cne-026919	Cryptococcus neoformans	43.39	0.00e+00	627.00
IUUC-Dre-027875	Danio rerio	94.98	0.00e+00	1471.00
IUUC-Dno-028931	Dasypus novemcinctus	95.10	0.00e+00	1504.00
IUUC-Dor-030846	Dipodomys ordii	96.69	0.00e+00	988.00
IUUC-Dse-031472	Dothistroma septosporum	46.23	0.00e+00	628.00
IUUC-Dme-031793	Drosophila melanogaster	62.23	0.00e+00	940.00
IUUC-Ete-033112	Echinops telfairi	85.71	2.00e-161	562.00
IUUC-Eca-034309	Equus caballus	94.97	0.00e+00	1507.00
IUUC-Eeu-034450	Erinaceus europaeus	66.92	0.00e+00	689.00
IUUC-Fca-036330	Felis catus	91.55	0.00e+00	1442.00
IUUC-Fal-036899	Ficedula albicollis	94.67	0.00e+00	1310.00
IUUC-Fox-037705	Fusarium oxysporum	49.50	0.00e+00	660.00
IUUC-Fso-038367	Fusarium solani	49.79	0.00e+00	681.00
IUUC-Gmo-038708	Gadus morhua	96.15	0.00e+00	1484.00
IUUC-Ggr-039917	Gaeumannomyces graminis	46.71	0.00e+00	670.00
IUUC-Gga-041038	Gallus gallus	95.10	0.00e+00	1509.00
IUUC-Gac-041820	Gasterosteus aculeatus	98.33	0.00e+00	1561.00
IUUC-Ggo-045154	Gorilla gorilla	79.89	0.00e+00	1060.00
IUUC-Hsa-046034	Homo sapiens	94.97	0.00e+00	1507.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	94.97	0.00e+00	1508.00
IUUC-Kpa-049231	Komagataella pastoris	38.28	3.00e-134	472.00
IUUC-Lch-049673	Latimeria chalumnae	94.85	0.00e+00	1502.00
IUUC-Loc-052490	Lepisosteus oculatus	96.01	0.00e+00	1499.00
IUUC-Lma-053191	Leptosphaeria maculans	48.25	0.00e+00	662.00
IUUC-Laf-054582	Loxodonta africana	94.85	0.00e+00	1506.00
IUUC-Mcc-055162	Macaca mulatta	94.07	0.00e+00	1487.00
IUUC-Meu-055904	Macropus eugenii	84.26	5.00e-153	534.00
IUUC-Mor-057035	Magnaporthe oryzae	46.63	0.00e+00	644.00
IUUC-Mpo-057555	Magnaporthe poae	46.71	0.00e+00	671.00
IUUC-Mla-059021	Melampsora laricipopulina	48.19	0.00e+00	658.00
IUUC-Mga-060078	Meleagris gallopavo	95.10	0.00e+00	1509.00
IUUC-Mvi-060519	Microbotryum violaceum	47.34	0.00e+00	667.00
IUUC-Mmr-061312	Microcebus murinus	94.97	0.00e+00	1507.00
IUUC-Mdo-062867	Monodelphis domestica	94.85	0.00e+00	1504.00
IUUC-Mmu-063336	Mus musculus	95.10	0.00e+00	1509.00
IUUC-Mpu-066400	Mustela putorius furo	94.53	0.00e+00	1309.00
IUUC-Mlu-067800	Myotis lucifugus	94.85	0.00e+00	1502.00
IUUC-Nfi-068384	Neosartorya fischeri	50.29	0.00e+00	640.00
IUUC-Ncr-068965	Neurospora crassa	48.02	0.00e+00	677.00
IUUC-Nle-069729	Nomascus leucogenys	94.97	0.00e+00	1507.00
IUUC-Ont-071729	Oreochromis niloticus	98.84	0.00e+00	1536.00
IUUC-Oan-073309	Ornithorhynchus anatinus	95.10	0.00e+00	1509.00
IUUC-Ocu-074661	Oryctolagus cuniculus	94.85	0.00e+00	1478.00
IUUC-Ola-087422	Oryzias latipes	97.43	0.00e+00	1541.00
IUUC-Oga-088130	Otolemur garnettii	94.97	0.00e+00	1507.00
IUUC-Oar-089510	Ovis aries	93.54	0.00e+00	1443.00
IUUC-Ptr-090665	Pan troglodytes	94.97	0.00e+00	1507.00
IUUC-Pan-092218	Papio anubis	94.97	0.00e+00	1507.00
IUUC-Psi-093175	Pelodiscus sinensis	94.97	0.00e+00	1508.00
IUUC-Pma-094502	Petromyzon marinus	88.52	0.00e+00	1398.00
IUUC-Pno-095067	Phaeosphaeria nodorum	48.26	0.00e+00	691.00
IUUC-Pfo-096705	Poecilia formosa	98.97	0.00e+00	1574.00
IUUC-Pab-097578	Pongo abelii	94.97	0.00e+00	1507.00
IUUC-Pca-100242	Procavia capensis	82.84	0.00e+00	1109.00
IUUC-Pva-102155	Pteropus vampyrus	83.38	0.00e+00	1285.00
IUUC-Pgr-103297	Puccinia graminis	46.31	0.00e+00	672.00
IUUC-Ptt-103706	Puccinia triticina	45.09	7.00e-93	335.00
IUUC-Pte-104257	Pyrenophora teres	48.65	0.00e+00	691.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	48.71	0.00e+00	691.00
IUUC-Rno-105939	Rattus norvegicus	95.10	0.00e+00	1509.00
IUUC-Sce-106293	Saccharomyces cerevisiae	31.81	6.00e-113	401.00
IUUC-Sha-106949	Sarcophilus harrisii	95.23	0.00e+00	1511.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	42.91	1.00e-157	550.00
IUUC-Spo-108280	Schizosaccharomyces pombe	41.41	2.00e-162	566.00
IUUC-Sre-114984	Sporisorium reilianum	45.70	1.00e-179	623.00
IUUC-Ssc-115829	Sus scrofa	94.35	0.00e+00	1489.00
IUUC-Tgu-116950	Taeniopygia guttata	95.10	0.00e+00	1509.00
IUUC-Tsy-118934	Tarsius syrichta	92.80	0.00e+00	702.00
IUUC-Tni-120460	Tetraodon nigroviridis	99.48	0.00e+00	1563.00
IUUC-Tre-122223	Trichoderma reesei	50.21	0.00e+00	643.00
IUUC-Tvi-122539	Trichoderma virens	45.24	2.00e-174	605.00
IUUC-Tme-126926	Tuber melanosporum	47.75	0.00e+00	678.00
IUUC-Tbe-127369	Tupaia belangeri	94.17	0.00e+00	627.00
IUUC-Ttr-129022	Tursiops truncatus	90.24	0.00e+00	1095.00
IUUC-Uma-129341	Ustilago maydis	45.40	4.00e-172	598.00
IUUC-Vda-129857	Verticillium dahliae	46.72	0.00e+00	645.00
IUUC-Vpa-130166	Vicugna pacos	89.08	0.00e+00	1164.00
IUUC-Xtr-131818	Xenopus tropicalis	94.59	0.00e+00	1496.00
IUUC-Xma-134206	Xiphophorus maculatus	98.45	0.00e+00	1526.00
IUUC-Yli-134486	Yarrowia lipolytica	39.77	2.00e-152	533.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence