iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012492

Ensembl Protein ID

ENSBTAP00000023029.3

UniProt Accession

Q17QV3; SUMO3_BOVIN

Genbank Protein ID

AAI18164.1

Protein Name

Small ubiquitin-related modifier 3

Genbank Nucleotide ID

BC118163

Gene Name

SUMO3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000017321.3	ENSBTAT00000023029.3	ENSBTAP00000023029.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	7.90e-33	113.2	14	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 6    kapvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
             +++lkvagqdGs v+fk+k++++l+klm+a Y++r++l+++++rf+f+gq+i+e++tp++le+eded+i++++q++GG
   Q: 14   NDHINLKVAGQDGSVVQFKIKRHTPLSKLMKA-YCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
           689*****************************.**********************************************9 PP

Organism

Bos taurus

Functional Description
(View)

Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX (By similarity).

Protein Sequence
(Fasta)

MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR 60
FDGQPINETD TPAQLEMEDE DTIDVFQQQT GGSRVASCLL GSGL 104

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGGCGGG CCGAGAGCGT GAGTCGCTCG CCCGGGGCTG CCTGCAGTCC CGCTGCCCTC 60
CGAGCGCAGC CATGTCCGAG GAGAAGCCCA AGGTAAGGGC CGGCGGGTGT GGGCCGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR027218--SUMO_2/3
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0031386--F:protein tag
GO:0016925--P:protein sumoylation

KEGG

bta:617236

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002090	Ailuropoda melanoleuca	96.81	7.00e-51	191.00
IUUC-Atr-002794	Amborella trichopoda	57.69	9.00e-21	90.90
IUUC-Aca-004778	Anolis carolinensis	100.00	2.00e-51	192.00
IUUC-Aly-005765	Arabidopsis lyrata	51.65	3.00e-21	92.80
IUUC-Ath-007391	Arabidopsis thaliana	52.75	1.00e-21	94.00
IUUC-Afl-008650	Aspergillus flavus	51.28	1.00e-17	80.90
IUUC-Afu-008969	Aspergillus fumigatus	50.00	2.00e-17	79.70
IUUC-Ani-009300	Aspergillus nidulans	48.72	2.00e-16	76.60
IUUC-Ang-009651	Aspergillus niger	51.28	3.00e-17	79.30
IUUC-Ate-010503	Aspergillus terreus	41.24	6.00e-15	72.40
IUUC-Ame-011304	Astyanax mexicanus	97.87	1.00e-51	193.00
IUUC-Bci-013625	Botrytis cinerea	47.06	2.00e-18	83.60
IUUC-Bdi-014847	Brachypodium distachyon	53.33	2.00e-21	93.20
IUUC-Bol-015977	Brassica oleracea	52.22	5.00e-21	92.00
IUUC-Bra-017542	Brassica rapa	52.22	4.00e-21	92.40
IUUC-Cja-019875	Callithrix jacchus	90.29	5.00e-50	188.00
IUUC-Cpo-022241	Cavia porcellus	98.92	2.00e-51	193.00
IUUC-Cre-022980	Chlamydomonas reinhardtii	45.45	2.00e-18	83.60
IUUC-Csa-023587	Chlorocebus sabaeus	100.00	2.00e-50	190.00
IUUC-Cin-025314	Ciona intestinalis	75.51	3.00e-37	145.00
IUUC-Csv-026212	Ciona savignyi	78.26	1.00e-38	150.00
IUUC-Cme-027181	Cyanidioschyzon merolae	53.76	2.00e-23	100.00
IUUC-Dre-027877	Danio rerio	98.92	2.00e-51	192.00
IUUC-Dse-031390	Dothistroma septosporum	50.00	7.00e-21	91.70
IUUC-Dme-031967	Drosophila melanogaster	70.97	7.00e-34	134.00
IUUC-Eca-033890	Equus caballus	93.88	3.00e-51	192.00
IUUC-Fca-036348	Felis catus	96.74	3.00e-49	186.00
IUUC-Fox-037950	Fusarium oxysporum	50.00	3.00e-20	89.40
IUUC-Gmo-039393	Gadus morhua	97.85	3.00e-51	192.00
IUUC-Ggr-040015	Gaeumannomyces graminis	56.41	6.00e-21	92.00
IUUC-Gga-040243	Gallus gallus	97.85	2.00e-49	186.00
IUUC-Gac-041576	Gasterosteus aculeatus	94.74	8.00e-51	191.00
IUUC-Gma-043216	Glycine max	57.50	2.00e-21	93.20
IUUC-Hsa-046074	Homo sapiens	100.00	2.00e-51	193.00
IUUC-Hvu-047514	Hordeum vulgare	53.33	7.00e-21	91.70
IUUC-Itr-048366	Ictidomys tridecemlineatus	95.65	2.00e-48	182.00
IUUC-Kpa-049243	Komagataella pastoris	48.39	2.00e-13	66.60
IUUC-Lch-050519	Latimeria chalumnae	90.22	6.00e-45	171.00
IUUC-Lpe-051129	Leersia perrieri	56.67	5.00e-24	102.00
IUUC-Loc-052130	Lepisosteus oculatus	97.83	2.00e-50	189.00
IUUC-Lma-052968	Leptosphaeria maculans	47.19	2.00e-18	83.20
IUUC-Mor-057132	Magnaporthe oryzae	54.43	2.00e-20	90.50
IUUC-Mpo-057351	Magnaporthe poae	56.41	6.00e-21	91.70
IUUC-Mtr-057985	Medicago truncatula	52.69	1.00e-21	94.40
IUUC-Mla-059030	Melampsora laricipopulina	39.36	1.00e-07	48.90
IUUC-Mvi-060478	Microbotryum violaceum	46.88	5.00e-12	62.00
IUUC-Mmr-061052	Microcebus murinus	97.94	5.00e-53	199.00
IUUC-Mmu-064045	Mus musculus	96.88	5.00e-50	188.00
IUUC-Mac-064925	Musa acuminata	57.14	3.00e-20	89.70
IUUC-Mpu-065686	Mustela putorius furo	98.86	1.00e-48	183.00
IUUC-Mlu-066949	Myotis lucifugus	93.88	8.00e-52	194.00
IUUC-Opr-071104	Ochotona princeps	30.00	9.00e-05	41.60
IUUC-Ont-071659	Oreochromis niloticus	98.91	8.00e-51	191.00
IUUC-Oan-073080	Ornithorhynchus anatinus	92.71	1.00e-48	184.00
IUUC-Oba-075425	Oryza barthii	59.26	1.00e-22	97.40
IUUC-Obr-076884	Oryza brachyantha	61.54	6.00e-23	98.60
IUUC-Ogl-077346	Oryza glaberrima	59.26	1.00e-22	97.40
IUUC-Ogu-078983	Oryza glumaepatula	53.33	6.00e-21	92.80
IUUC-Oin-079503	Oryza indica	59.26	1.00e-22	97.40
IUUC-Olo-080573	Oryza longistaminata	59.26	1.00e-22	97.40
IUUC-Ome-081885	Oryza meridionalis	60.26	2.00e-22	97.40
IUUC-Oni-082762	Oryza nivara	59.26	1.00e-22	97.40
IUUC-Opu-083431	Oryza punctata	59.26	3.00e-22	98.20
IUUC-Oru-084392	Oryza rufipogon	59.26	1.00e-22	97.40
IUUC-Osa-086070	Oryza sativa	59.26	1.00e-22	97.40
IUUC-Ola-086379	Oryzias latipes	98.90	3.00e-50	189.00
IUUC-Oga-088989	Otolemur garnettii	95.05	1.00e-53	200.00
IUUC-Oar-089406	Ovis aries	96.94	5.00e-53	198.00
IUUC-Ptr-091447	Pan troglodytes	100.00	2.00e-51	193.00
IUUC-Pno-094884	Phaeosphaeria nodorum	46.67	2.00e-19	86.70
IUUC-Ppa-095772	Physcomitrella patens	51.65	4.00e-20	89.40
IUUC-Pfo-097413	Poecilia formosa	98.91	9.00e-51	190.00
IUUC-Pop-099042	Populus trichocarpa	51.96	2.00e-21	94.00
IUUC-Pgr-103683	Puccinia graminis	44.94	3.00e-15	73.60
IUUC-Ptt-103986	Puccinia triticina	46.84	1.00e-14	71.20
IUUC-Pte-104358	Pyrenophora teres	47.78	6.00e-20	88.20
IUUC-Pyt-104485	Pyrenophora triticirepentis	47.78	6.00e-20	88.20
IUUC-Rno-105136	Rattus norvegicus	98.92	2.00e-51	193.00
IUUC-Sha-106682	Sarcophilus harrisii	96.59	4.00e-48	182.00
IUUC-Smo-109229	Selaginella moellendorffii	50.55	2.00e-20	90.10
IUUC-Sly-110855	Solanum lycopersicum	53.57	1.00e-20	91.30
IUUC-Stu-111935	Solanum tuberosum	54.22	1.00e-21	94.40
IUUC-Sbi-114801	Sorghum bicolor	53.33	1.00e-21	94.00
IUUC-Ssc-116092	Sus scrofa	93.27	6.00e-53	197.00
IUUC-Tru-118409	Takifugu rubripes	97.83	4.00e-50	188.00
IUUC-Tni-120059	Tetraodon nigroviridis	97.83	4.00e-50	188.00
IUUC-Tae-125013	Triticum aestivum	57.50	5.00e-22	95.50
IUUC-Tur-126333	Triticum urartu	43.27	2.00e-16	78.60
IUUC-Tbe-127363	Tupaia belangeri	91.40	1.00e-45	173.00
IUUC-Vda-129731	Verticillium dahliae	44.90	3.00e-19	86.30
IUUC-Vvi-131743	Vitis vinifera	56.25	7.00e-21	91.70
IUUC-Xtr-132678	Xenopus tropicalis	98.91	7.00e-51	191.00
IUUC-Xma-133518	Xiphophorus maculatus	98.91	5.00e-51	191.00
IUUC-Zma-134810	Zea mays	54.95	4.00e-22	95.50

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence