iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.70e-08	35.0	59	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 95   eegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
             + ++ ++drlp++ +v+i+++l++++l+r+arvcrrw++la +++lw+t+
   Q: 59   RPQKEQASIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTI 110
           345678899*******************************99999****997 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRTLSTPSPA LICPPALPGF QNGRGSSTSS SSITGETVAM VHSPPPTRLT HPLIRLASRP 60
QKEQASIDRL PDHSMVQIFS FLPTNQLCRC ARVCRRWYNL AWDPRLWRTI RLTGETINVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGACTTGA GCATGCGCAC ACTGAGCACG CCCAGCCCAG CCTTGATATG TCCACCAGCT 60
TTGCCAGGAT TTCAGAATGG AAGGGGCTCG TCCACATCTT CATCCTCCAT CACTGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005813--C:centrosome
GO:0019005--C:SCF ubiquitin ligase complex
GO:0008283--P:cell proliferation
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0007067--P:mitotic nuclear division
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002298	Ailuropoda melanoleuca	97.52	0.00e+00	873.00
IUUC-Apl-003410	Anas platyrhynchos	95.95	0.00e+00	864.00
IUUC-Aca-004422	Anolis carolinensis	91.67	0.00e+00	830.00
IUUC-Aly-006311	Arabidopsis lyrata	27.01	8.00e-28	118.00
IUUC-Ago-007947	Ashbya gossypii	26.29	2.00e-23	104.00
IUUC-Afl-008576	Aspergillus flavus	26.61	4.00e-26	113.00
IUUC-Aor-010050	Aspergillus oryzae	26.61	4.00e-26	113.00
IUUC-Ame-010878	Astyanax mexicanus	82.70	0.00e+00	729.00
IUUC-Bgr-012097	Blumeria graminis	26.20	4.00e-27	117.00
IUUC-Bta-013145	Bos taurus	97.52	0.00e+00	874.00
IUUC-Bra-016671	Brassica rapa	30.88	3.00e-29	123.00
IUUC-Cja-019612	Callithrix jacchus	97.52	0.00e+00	871.00
IUUC-Cfa-020920	Canis familiaris	86.94	0.00e+00	788.00
IUUC-Cpo-022293	Cavia porcellus	97.07	0.00e+00	873.00
IUUC-Csa-024100	Chlorocebus sabaeus	98.87	0.00e+00	881.00
IUUC-Dre-028464	Danio rerio	81.12	0.00e+00	734.00
IUUC-Dno-028849	Dasypus novemcinctus	97.07	0.00e+00	873.00
IUUC-Dor-030835	Dipodomys ordii	88.40	7.00e-90	324.00
IUUC-Dme-031686	Drosophila melanogaster	49.21	3.00e-108	386.00
IUUC-Eca-034259	Equus caballus	98.42	0.00e+00	882.00
IUUC-Fca-035850	Felis catus	97.30	0.00e+00	873.00
IUUC-Fal-037009	Ficedula albicollis	95.50	0.00e+00	864.00
IUUC-Fox-037823	Fusarium oxysporum	26.07	2.00e-33	137.00
IUUC-Gmo-038560	Gadus morhua	72.85	5.00e-100	356.00
IUUC-Gga-040391	Gallus gallus	95.50	0.00e+00	862.00
IUUC-Gac-041464	Gasterosteus aculeatus	72.20	0.00e+00	627.00
IUUC-Ggo-044556	Gorilla gorilla	98.87	0.00e+00	880.00
IUUC-Hsa-046685	Homo sapiens	98.65	0.00e+00	883.00
IUUC-Itr-048013	Ictidomys tridecemlineatus	98.42	0.00e+00	880.00
IUUC-Kpa-049189	Komagataella pastoris	24.94	2.00e-19	91.70
IUUC-Lch-050268	Latimeria chalumnae	90.32	0.00e+00	796.00
IUUC-Loc-051910	Lepisosteus oculatus	90.09	0.00e+00	810.00
IUUC-Laf-053599	Loxodonta africana	97.30	0.00e+00	871.00
IUUC-Mcc-055225	Macaca mulatta	98.65	0.00e+00	883.00
IUUC-Meu-056341	Macropus eugenii	96.17	0.00e+00	866.00
IUUC-Mga-059525	Meleagris gallopavo	95.50	0.00e+00	856.00
IUUC-Mmr-060571	Microcebus murinus	98.42	0.00e+00	882.00
IUUC-Mdo-062229	Monodelphis domestica	96.85	0.00e+00	868.00
IUUC-Mmu-063408	Mus musculus	99.77	0.00e+00	895.00
IUUC-Mpu-065742	Mustela putorius furo	97.97	0.00e+00	877.00
IUUC-Mlu-067442	Myotis lucifugus	97.48	0.00e+00	858.00
IUUC-Nle-069404	Nomascus leucogenys	98.42	0.00e+00	880.00
IUUC-Opr-070457	Ochotona princeps	97.52	0.00e+00	874.00
IUUC-Ont-072288	Oreochromis niloticus	72.20	0.00e+00	632.00
IUUC-Oan-073492	Ornithorhynchus anatinus	94.59	0.00e+00	852.00
IUUC-Ocu-074513	Oryctolagus cuniculus	97.52	0.00e+00	872.00
IUUC-Ola-086573	Oryzias latipes	72.44	0.00e+00	630.00
IUUC-Olu-087656	Ostreococcus lucimarinus	27.10	1.00e-06	47.40
IUUC-Oga-088674	Otolemur garnettii	97.30	0.00e+00	872.00
IUUC-Oar-090268	Ovis aries	91.22	0.00e+00	819.00
IUUC-Ptr-091375	Pan troglodytes	98.65	0.00e+00	883.00
IUUC-Pan-091683	Papio anubis	98.65	0.00e+00	880.00
IUUC-Psi-093199	Pelodiscus sinensis	96.17	0.00e+00	866.00
IUUC-Pma-094494	Petromyzon marinus	54.07	3.00e-113	401.00
IUUC-Pno-094936	Phaeosphaeria nodorum	24.94	4.00e-20	93.60
IUUC-Pfo-097004	Poecilia formosa	72.51	0.00e+00	632.00
IUUC-Pab-098590	Pongo abelii	98.42	0.00e+00	878.00
IUUC-Pca-100228	Procavia capensis	95.79	0.00e+00	744.00
IUUC-Pva-103166	Pteropus vampyrus	97.30	0.00e+00	868.00
IUUC-Ptt-103850	Puccinia triticina	23.02	2.00e-07	50.80
IUUC-Sha-107379	Sarcophilus harrisii	96.40	0.00e+00	864.00
IUUC-Ssl-108575	Sclerotinia sclerotiorum	27.73	6.00e-16	79.70
IUUC-Sly-111591	Solanum lycopersicum	34.40	1.00e-30	128.00
IUUC-Stu-112488	Solanum tuberosum	33.83	5.00e-30	125.00
IUUC-Sar-113379	Sorex araneus	96.40	0.00e+00	867.00
IUUC-Ssc-115408	Sus scrofa	97.97	0.00e+00	878.00
IUUC-Tgu-117432	Taeniopygia guttata	95.72	0.00e+00	862.00
IUUC-Tru-117799	Takifugu rubripes	73.35	0.00e+00	632.00
IUUC-Tsy-119149	Tarsius syrichta	70.81	6.00e-54	204.00
IUUC-Tni-120688	Tetraodon nigroviridis	72.86	0.00e+00	626.00
IUUC-Tbe-127372	Tupaia belangeri	97.52	0.00e+00	870.00
IUUC-Ttr-128176	Tursiops truncatus	96.62	0.00e+00	865.00
IUUC-Vpa-130343	Vicugna pacos	98.77	1.00e-140	493.00
IUUC-Xtr-132187	Xenopus tropicalis	93.92	0.00e+00	851.00
IUUC-Xma-134176	Xiphophorus maculatus	72.51	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence