iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089557

Ensembl Protein ID

ENSOARP00000022117.1

UniProt Accession

W5QHB7; W5QHB7_SHEEP

Genbank Protein ID

ENSOARP00000022117

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01102757

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020579.1	ENSOART00000022422.1	ENSOARP00000022117.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.70e-40	137.2	215	291
E3 activity/RING/RING	1.70e-08	35.0	1090	1193
E3 activity/N-recognin/UBR-box	5.30e-31	107.1	86	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al++e++ea++++t+idkeGRravkaG++a+c+eak++i+++se+++q+pL+Vev
   Q: 215  YYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGAFAACQEAKEDIKSHSENVSQHPLHVEV 291
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiC.......................................ledf......kdgplvlpCgHvfhadClqkw............. 29
           C++C                                       ++++       +g+++++CgHv+ha C+qk+             
   Q: 1090 CILCqeeqevkiennamvlsacvqkstaltqhrgkpielsgetMDPLfmdadlAYGTYTGSCGHVMHAVCWQKYfeavqlssqqrih 1176
           88883333333333333333333333333333333333333331211333333457999**************************** PP
   S: 30   pglknssskefrCPlCr 46
           ++l +++s+e +CPlC+
   Q: 1177 VDLFDLESGEYLCPLCK 1193
           ****************7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk+get+y+Cr+C++d+t+vlC++Cf+++vHk+H+yk+++s+gggfCdCGdteAw++g++C +++
   Q: 86   QLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQNSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCISHE 156
           68*****************************************************************9986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MEVSTELPQT PQQLASWWDQ QIDFYTTFLN YLAQVVPEIY FAEMDPDLEK QEESIQRSIF 60
TPLEWYLFGE DPDICLEKLK HSGAFQLCGK VFKSGETTYS CRDCAIDPTC VLCMDCFQNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGACG AGGAGGCTGG GGACACAGAG AGGATGGAAG TCAGCACGGA GTTGCCGCAG 60
ACCCCTCAGC AACTGGCGTC TGTAAGTCCC TGAAGGCCAG TTCCTTTTGT AACCTCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	94.29	0.00e+00	3310.00
IUUC-Apl-004160	Anas platyrhynchos	77.53	0.00e+00	2721.00
IUUC-Aca-004982	Anolis carolinensis	74.41	0.00e+00	2631.00
IUUC-Ago-007752	Ashbya gossypii	27.16	4.00e-23	104.00
IUUC-Acl-008055	Aspergillus clavatus	23.67	2.00e-34	142.00
IUUC-Afl-008479	Aspergillus flavus	23.22	8.00e-44	173.00
IUUC-Afu-008929	Aspergillus fumigatus	22.69	4.00e-49	191.00
IUUC-Ang-009550	Aspergillus niger	24.00	1.00e-44	176.00
IUUC-Aor-010124	Aspergillus oryzae	23.27	2.00e-43	172.00
IUUC-Ate-010550	Aspergillus terreus	22.96	8.00e-47	183.00
IUUC-Ame-011231	Astyanax mexicanus	57.13	0.00e+00	1875.00
IUUC-Bgr-011999	Blumeria graminis	23.15	5.00e-46	181.00
IUUC-Bta-012347	Bos taurus	98.34	0.00e+00	3441.00
IUUC-Bci-013834	Botrytis cinerea	23.21	6.00e-42	167.00
IUUC-Cja-018911	Callithrix jacchus	88.97	0.00e+00	3134.00
IUUC-Cfa-020991	Canis familiaris	95.09	0.00e+00	3343.00
IUUC-Cpo-021448	Cavia porcellus	90.80	0.00e+00	3209.00
IUUC-Csa-024255	Chlorocebus sabaeus	93.07	0.00e+00	2712.00
IUUC-Cho-024550	Choloepus hoffmanni	71.96	0.00e+00	2410.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	24.25	9.00e-52	199.00
IUUC-Dno-029427	Dasypus novemcinctus	91.42	0.00e+00	3152.00
IUUC-Dor-031073	Dipodomys ordii	79.14	0.00e+00	1380.00
IUUC-Ete-032318	Echinops telfairi	75.30	0.00e+00	1237.00
IUUC-Eca-033348	Equus caballus	94.28	0.00e+00	3079.00
IUUC-Eeu-034664	Erinaceus europaeus	84.29	0.00e+00	2963.00
IUUC-Fca-035604	Felis catus	89.83	0.00e+00	1541.00
IUUC-Fal-037333	Ficedula albicollis	77.12	0.00e+00	2682.00
IUUC-Fox-037984	Fusarium oxysporum	26.86	1.00e-40	162.00
IUUC-Fso-038463	Fusarium solani	25.24	1.00e-42	170.00
IUUC-Gmo-039363	Gadus morhua	55.50	0.00e+00	1633.00
IUUC-Ggr-040070	Gaeumannomyces graminis	26.39	1.00e-40	162.00
IUUC-Gga-040486	Gallus gallus	76.42	0.00e+00	2642.00
IUUC-Gac-041985	Gasterosteus aculeatus	56.94	0.00e+00	1732.00
IUUC-Ggo-044704	Gorilla gorilla	86.64	0.00e+00	2553.00
IUUC-Hsa-046753	Homo sapiens	93.38	0.00e+00	3297.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	93.49	0.00e+00	3276.00
IUUC-Lch-049904	Latimeria chalumnae	61.56	0.00e+00	2110.00
IUUC-Loc-052624	Lepisosteus oculatus	60.83	0.00e+00	2043.00
IUUC-Lma-053059	Leptosphaeria maculans	22.65	3.00e-44	175.00
IUUC-Laf-053857	Loxodonta africana	89.59	0.00e+00	3152.00
IUUC-Mcc-054873	Macaca mulatta	93.43	0.00e+00	3260.00
IUUC-Meu-056858	Macropus eugenii	67.17	0.00e+00	1032.00
IUUC-Mor-057051	Magnaporthe oryzae	23.42	7.00e-46	180.00
IUUC-Mpo-057372	Magnaporthe poae	26.93	5.00e-41	164.00
IUUC-Mga-059917	Meleagris gallopavo	76.91	0.00e+00	2754.00
IUUC-Mmr-061128	Microcebus murinus	89.83	0.00e+00	3107.00
IUUC-Mdo-062306	Monodelphis domestica	80.45	0.00e+00	2819.00
IUUC-Mmu-063389	Mus musculus	90.92	0.00e+00	3230.00
IUUC-Mpu-065983	Mustela putorius furo	94.92	0.00e+00	3357.00
IUUC-Mlu-068013	Myotis lucifugus	91.10	0.00e+00	3212.00
IUUC-Nfi-068403	Neosartorya fischeri	22.63	1.00e-50	196.00
IUUC-Ncr-068864	Neurospora crassa	25.00	4.00e-37	151.00
IUUC-Nle-070031	Nomascus leucogenys	93.66	0.00e+00	3305.00
IUUC-Opr-070551	Ochotona princeps	70.59	0.00e+00	1355.00
IUUC-Ont-072035	Oreochromis niloticus	57.53	0.00e+00	1949.00
IUUC-Ocu-074930	Oryctolagus cuniculus	89.08	0.00e+00	3107.00
IUUC-Oba-075295	Oryza barthii	38.54	6.00e-14	74.30
IUUC-Obr-076117	Oryza brachyantha	24.85	4.00e-27	118.00
IUUC-Ogl-077571	Oryza glaberrima	24.29	5.00e-26	114.00
IUUC-Ogu-078497	Oryza glumaepatula	38.54	6.00e-14	74.30
IUUC-Oin-079343	Oryza indica	38.54	6.00e-14	74.30
IUUC-Olo-081056	Oryza longistaminata	38.54	5.00e-14	74.70
IUUC-Ome-081738	Oryza meridionalis	35.29	4.00e-13	71.60
IUUC-Oni-083099	Oryza nivara	38.54	6.00e-14	74.30
IUUC-Oru-084471	Oryza rufipogon	38.54	6.00e-14	74.30
IUUC-Osa-085336	Oryza sativa	24.18	3.00e-25	110.00
IUUC-Ola-086683	Oryzias latipes	57.15	0.00e+00	1895.00
IUUC-Oga-088017	Otolemur garnettii	89.92	0.00e+00	3113.00
IUUC-Ptr-091366	Pan troglodytes	92.29	0.00e+00	3274.00
IUUC-Pan-092184	Papio anubis	93.43	0.00e+00	3260.00
IUUC-Psi-093720	Pelodiscus sinensis	77.40	0.00e+00	2677.00
IUUC-Pfo-097124	Poecilia formosa	57.15	0.00e+00	1913.00
IUUC-Pab-098586	Pongo abelii	93.72	0.00e+00	3303.00
IUUC-Pop-099184	Populus trichocarpa	44.21	2.00e-13	70.50
IUUC-Pca-100673	Procavia capensis	84.26	0.00e+00	1704.00
IUUC-Pva-102724	Pteropus vampyrus	91.07	0.00e+00	2511.00
IUUC-Pte-104174	Pyrenophora teres	22.96	2.00e-46	182.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	22.96	2.00e-45	178.00
IUUC-Rno-105474	Rattus norvegicus	87.72	0.00e+00	2326.00
IUUC-Sha-106993	Sarcophilus harrisii	80.66	0.00e+00	2903.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	23.72	6.00e-47	184.00
IUUC-Spo-108084	Schizosaccharomyces pombe	25.09	9.00e-37	150.00
IUUC-Sar-113447	Sorex araneus	88.67	0.00e+00	2155.00
IUUC-Sre-115045	Sporisorium reilianum	24.39	2.00e-42	169.00
IUUC-Ssc-115768	Sus scrofa	91.57	0.00e+00	2994.00
IUUC-Tgu-116949	Taeniopygia guttata	72.35	0.00e+00	2463.00
IUUC-Tru-117782	Takifugu rubripes	56.85	0.00e+00	1914.00
IUUC-Tsy-119177	Tarsius syrichta	81.96	0.00e+00	2225.00
IUUC-Tni-120884	Tetraodon nigroviridis	53.03	0.00e+00	1745.00
IUUC-Tre-122137	Trichoderma reesei	25.00	4.00e-59	224.00
IUUC-Tbe-128088	Tupaia belangeri	80.62	0.00e+00	1253.00
IUUC-Ttr-129062	Tursiops truncatus	90.07	0.00e+00	3119.00
IUUC-Uma-129344	Ustilago maydis	25.09	3.00e-48	188.00
IUUC-Vda-129778	Verticillium dahliae	25.21	4.00e-42	168.00
IUUC-Vpa-130578	Vicugna pacos	87.32	0.00e+00	2991.00
IUUC-Vvi-130900	Vitis vinifera	44.79	1.00e-12	67.80
IUUC-Xtr-132244	Xenopus tropicalis	60.71	0.00e+00	2092.00
IUUC-Xma-134112	Xiphophorus maculatus	57.36	0.00e+00	1920.00
IUUC-Yli-134662	Yarrowia lipolytica	22.47	2.00e-29	125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence