iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069175

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

ADFV01174587

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016165.2	ENSNLET00000020588.2	ENSNLEP00000019598.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.40e-64	218.6	38	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 21   lvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsvll 109
           +++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++d++++++f+kq+i+N+C+t++l+++++
   Q: 38   FLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIA 124
           689*********************************************766..5589******************************** PP
   S: 110  ncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglk 197
           n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf+++v+++g+lyeldg+k
   Q: 125  NNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPSID-------EKVDLHFIALVHVDGHLYELDGRK 206
           *******************************************************888.......8899******************** PP
   S: 198  pfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           pfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 207  PFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 249
           ****************************....***********9875 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGSVWDSRPG LERTPPDQRF RFHFCPSRPG AWGGRSGFLK QLGLHPNWQF VDVYGMDPEL 60
LSMVPRPVCA VLLLFPITEK YEVFRTEEEE KIKSQGQDVT SSVYFMKQTI SNACGTIGLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCAGCG TCTGGGACTC GCGCCCGGGA CTCGAGAGAA CGCCCCCCGA CCAGCGCTTC 60
CGCTTCCACT TCTGCCCCTC GCGGCCTGGC GCATGGGGCG GACGTAGCGG GGTAAGCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001344	Ailuropoda melanoleuca	100.00	1.00e-124	437.00
IUUC-Atr-002931	Amborella trichopoda	48.37	6.00e-48	183.00
IUUC-Apl-003949	Anas platyrhynchos	87.26	2.00e-103	367.00
IUUC-Aca-004924	Anolis carolinensis	83.02	6.00e-106	376.00
IUUC-Aly-005721	Arabidopsis lyrata	48.82	1.00e-51	196.00
IUUC-Ath-006827	Arabidopsis thaliana	49.29	5.00e-52	197.00
IUUC-Ago-007950	Ashbya gossypii	33.80	2.00e-23	102.00
IUUC-Acl-008305	Aspergillus clavatus	40.09	3.00e-39	155.00
IUUC-Afl-008611	Aspergillus flavus	40.09	9.00e-39	153.00
IUUC-Afu-008945	Aspergillus fumigatus	40.36	2.00e-38	152.00
IUUC-Ani-009339	Aspergillus nidulans	40.18	5.00e-39	154.00
IUUC-Ang-009691	Aspergillus niger	38.18	3.00e-38	151.00
IUUC-Aor-009961	Aspergillus oryzae	40.09	9.00e-39	153.00
IUUC-Ate-010316	Aspergillus terreus	40.18	1.00e-39	155.00
IUUC-Ame-011157	Astyanax mexicanus	72.17	3.00e-90	323.00
IUUC-Bgr-012125	Blumeria graminis	35.48	2.00e-35	142.00
IUUC-Bta-012673	Bos taurus	99.06	8.00e-124	435.00
IUUC-Bci-013734	Botrytis cinerea	37.10	8.00e-38	150.00
IUUC-Bol-015214	Brassica oleracea	50.71	4.00e-54	204.00
IUUC-Bra-017491	Brassica rapa	51.18	7.00e-54	203.00
IUUC-Cfa-020371	Canis familiaris	97.37	1.00e-106	378.00
IUUC-Cpo-022036	Cavia porcellus	96.23	1.00e-118	418.00
IUUC-Csa-023854	Chlorocebus sabaeus	99.06	7.00e-123	432.00
IUUC-Cin-025545	Ciona intestinalis	48.34	1.00e-58	219.00
IUUC-Cgl-026409	Colletotrichum gloeosporioides	33.18	1.00e-26	112.00
IUUC-Cne-026914	Cryptococcus neoformans	35.35	5.00e-27	114.00
IUUC-Cme-027216	Cyanidioschyzon merolae	36.70	2.00e-22	99.00
IUUC-Dre-028356	Danio rerio	72.64	2.00e-91	327.00
IUUC-Dse-031461	Dothistroma septosporum	39.29	9.00e-34	136.00
IUUC-Dme-032146	Drosophila melanogaster	49.53	4.00e-56	211.00
IUUC-Eca-033220	Equus caballus	99.53	2.00e-123	434.00
IUUC-Fca-036421	Felis catus	100.00	1.00e-124	437.00
IUUC-Fal-036773	Ficedula albicollis	87.26	4.00e-103	367.00
IUUC-Fox-037830	Fusarium oxysporum	35.75	3.00e-36	145.00
IUUC-Fso-038259	Fusarium solani	35.94	2.00e-34	141.00
IUUC-Gmo-039468	Gadus morhua	68.72	3.00e-76	277.00
IUUC-Ggr-039832	Gaeumannomyces graminis	36.11	4.00e-32	131.00
IUUC-Gga-041205	Gallus gallus	86.79	1.00e-102	365.00
IUUC-Gac-041629	Gasterosteus aculeatus	68.40	2.00e-79	288.00
IUUC-Gma-043057	Glycine max	47.39	1.00e-44	172.00
IUUC-Ggo-044533	Gorilla gorilla	100.00	1.00e-124	438.00
IUUC-Hsa-046754	Homo sapiens	100.00	1.00e-124	437.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	99.29	4.00e-80	289.00
IUUC-Kpa-049123	Komagataella pastoris	36.45	8.00e-29	120.00
IUUC-Lch-049685	Latimeria chalumnae	78.10	3.00e-99	353.00
IUUC-Loc-051988	Lepisosteus oculatus	75.94	4.00e-95	340.00
IUUC-Lma-053316	Leptosphaeria maculans	39.73	3.00e-40	158.00
IUUC-Laf-053985	Loxodonta africana	98.58	3.00e-123	434.00
IUUC-Mcc-055888	Macaca mulatta	99.06	4.00e-124	436.00
IUUC-Mor-057271	Magnaporthe oryzae	36.79	5.00e-36	144.00
IUUC-Mtr-057713	Medicago truncatula	46.45	5.00e-45	174.00
IUUC-Mla-058942	Melampsora laricipopulina	44.50	8.00e-40	156.00
IUUC-Mga-059702	Meleagris gallopavo	86.79	5.00e-103	366.00
IUUC-Mvi-060249	Microbotryum violaceum	43.00	1.00e-34	139.00
IUUC-Mmr-061284	Microcebus murinus	100.00	7.00e-80	290.00
IUUC-Mdo-062639	Monodelphis domestica	79.20	1.00e-111	395.00
IUUC-Mmu-063299	Mus musculus	98.11	7.00e-123	432.00
IUUC-Mac-065075	Musa acuminata	44.50	4.00e-45	174.00
IUUC-Mpu-066769	Mustela putorius furo	100.00	1.00e-124	437.00
IUUC-Mlu-066937	Myotis lucifugus	97.64	1.00e-121	428.00
IUUC-Nfi-068320	Neosartorya fischeri	40.81	2.00e-39	155.00
IUUC-Ncr-068673	Neurospora crassa	37.73	2.00e-40	158.00
IUUC-Opr-070652	Ochotona princeps	100.00	7.00e-64	236.00
IUUC-Ont-072170	Oreochromis niloticus	70.75	6.00e-81	293.00
IUUC-Oan-073247	Ornithorhynchus anatinus	94.74	5.00e-50	188.00
IUUC-Ocu-074422	Oryctolagus cuniculus	98.11	2.00e-123	434.00
IUUC-Ola-086893	Oryzias latipes	68.40	2.00e-77	281.00
IUUC-Olu-087858	Ostreococcus lucimarinus	42.06	4.00e-44	170.00
IUUC-Oga-088055	Otolemur garnettii	100.00	1.00e-124	438.00
IUUC-Oar-090319	Ovis aries	98.58	3.00e-123	433.00
IUUC-Pan-092714	Papio anubis	99.06	1.00e-123	434.00
IUUC-Psi-094036	Pelodiscus sinensis	87.26	2.00e-103	368.00
IUUC-Pma-094412	Petromyzon marinus	62.86	2.00e-46	177.00
IUUC-Pno-094997	Phaeosphaeria nodorum	35.27	6.00e-30	124.00
IUUC-Ppa-095519	Physcomitrella patens	49.05	2.00e-55	208.00
IUUC-Pfo-096182	Poecilia formosa	67.76	8.00e-80	289.00
IUUC-Pab-098216	Pongo abelii	100.00	8.00e-83	298.00
IUUC-Pop-099282	Populus trichocarpa	46.92	8.00e-45	173.00
IUUC-Ppe-101332	Prunus persica	45.97	4.00e-47	181.00
IUUC-Pgr-103430	Puccinia graminis	46.36	2.00e-43	168.00
IUUC-Ptt-103955	Puccinia triticina	48.78	5.00e-44	170.00
IUUC-Pte-104414	Pyrenophora teres	37.34	9.00e-36	143.00
IUUC-Rno-105096	Rattus norvegicus	97.17	7.00e-122	429.00
IUUC-Sce-106412	Saccharomyces cerevisiae	31.86	4.00e-24	104.00
IUUC-Sha-106677	Sarcophilus harrisii	87.61	8.00e-119	419.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	28.79	2.00e-21	95.50
IUUC-Ssl-108641	Sclerotinia sclerotiorum	36.89	1.00e-35	142.00
IUUC-Smo-108914	Selaginella moellendorffii	47.47	2.00e-45	175.00
IUUC-Sit-110163	Setaria italica	45.37	1.00e-46	179.00
IUUC-Sly-111613	Solanum lycopersicum	48.34	1.00e-53	202.00
IUUC-Sbi-114545	Sorghum bicolor	44.60	3.00e-44	171.00
IUUC-Sre-114961	Sporisorium reilianum	44.17	2.00e-35	142.00
IUUC-Ssc-115255	Sus scrofa	97.64	4.00e-122	429.00
IUUC-Tgu-117003	Taeniopygia guttata	86.92	3.00e-103	367.00
IUUC-Tru-118330	Takifugu rubripes	63.64	1.00e-61	230.00
IUUC-Tsy-119488	Tarsius syrichta	98.25	5.00e-63	233.00
IUUC-Tni-120042	Tetraodon nigroviridis	65.43	8.00e-63	234.00
IUUC-Tca-120976	Theobroma cacao	45.50	4.00e-47	181.00
IUUC-Tre-122149	Trichoderma reesei	37.90	8.00e-39	153.00
IUUC-Tvi-122450	Trichoderma virens	38.25	2.00e-38	152.00
IUUC-Tme-126961	Tuber melanosporum	36.49	6.00e-32	130.00
IUUC-Uma-129382	Ustilago maydis	40.91	8.00e-38	150.00
IUUC-Vda-129678	Verticillium dahliae	30.70	4.00e-25	107.00
IUUC-Vpa-130783	Vicugna pacos	99.13	3.00e-63	234.00
IUUC-Vvi-131661	Vitis vinifera	46.48	9.00e-49	186.00
IUUC-Xtr-132428	Xenopus tropicalis	75.00	2.00e-97	348.00
IUUC-Xma-134245	Xiphophorus maculatus	67.62	6.00e-80	290.00
IUUC-Yli-134570	Yarrowia lipolytica	35.45	1.00e-32	132.00
IUUC-Zma-134740	Zea mays	43.66	8.00e-46	176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence