iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089987

Ensembl Protein ID

ENSOARP00000014413.1

UniProt Accession

W5PVD0; W5PVD0_SHEEP

Genbank Protein ID

ENSOARP00000014413

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01067750

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013443.1	ENSOART00000014625.1	ENSOARP00000014413.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.10e-27	93.1	211	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 211  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 284
           69********************************************************************9986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLVSWFQPRA SSWDGVGRLS SLPHAGWPGL GPQTRNPLVA VYYTNRALCY LKMQQHEQAL 60
ADCRRALELE GQVKAHFFLG QCQLEMESYD EAIANLQRAY NLAKEQRLNF GDDIPSALRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGGGGAG GGGCCGAGCT GCGGCTTCTG CCGCGCTCCC TCTTCAGAAC ATATCAGGCC 60
GTGCCCGCCA GACTTTCGGA GGGAGGGGGT GGGTGCTTGG GGTCTGGGGC CAAGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	35.38	2.00e-35	142.00
IUUC-Aml-001350	Ailuropoda melanoleuca	96.09	9.00e-144	502.00
IUUC-Atr-003168	Amborella trichopoda	32.88	2.00e-29	122.00
IUUC-Apl-003736	Anas platyrhynchos	86.38	5.00e-129	452.00
IUUC-Aca-004751	Anolis carolinensis	84.82	2.00e-124	438.00
IUUC-Aly-006292	Arabidopsis lyrata	32.94	1.00e-35	143.00
IUUC-Ath-007012	Arabidopsis thaliana	32.94	5.00e-35	140.00
IUUC-Acl-008025	Aspergillus clavatus	29.12	6.00e-28	117.00
IUUC-Afl-008721	Aspergillus flavus	28.90	2.00e-24	105.00
IUUC-Afu-008853	Aspergillus fumigatus	29.81	2.00e-26	112.00
IUUC-Ani-009349	Aspergillus nidulans	30.15	4.00e-27	114.00
IUUC-Ang-009674	Aspergillus niger	30.57	9.00e-24	103.00
IUUC-Aor-010014	Aspergillus oryzae	28.90	2.00e-24	105.00
IUUC-Ate-010467	Aspergillus terreus	27.00	3.00e-20	92.00
IUUC-Ame-011215	Astyanax mexicanus	58.59	8.00e-78	283.00
IUUC-Bgr-011971	Blumeria graminis	29.92	6.00e-18	84.30
IUUC-Bta-013025	Bos taurus	96.06	2.00e-142	497.00
IUUC-Bci-013945	Botrytis cinerea	41.03	2.00e-14	72.80
IUUC-Bdi-014483	Brachypodium distachyon	37.60	1.00e-38	153.00
IUUC-Bol-015676	Brassica oleracea	33.07	6.00e-36	145.00
IUUC-Bra-017897	Brassica rapa	30.80	2.00e-28	118.00
IUUC-Cel-018323	Caenorhabditis elegans	41.27	4.00e-49	187.00
IUUC-Cja-019657	Callithrix jacchus	93.75	3.00e-141	493.00
IUUC-Cfa-020470	Canis familiaris	96.20	2.00e-131	461.00
IUUC-Cpo-022033	Cavia porcellus	93.75	7.00e-141	493.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	25.65	1.00e-20	93.20
IUUC-Csa-023038	Chlorocebus sabaeus	92.97	1.00e-134	472.00
IUUC-Cin-025381	Ciona intestinalis	52.34	9.00e-76	276.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	30.35	1.00e-29	123.00
IUUC-Dre-027610	Danio rerio	78.52	8.00e-117	412.00
IUUC-Dno-030087	Dasypus novemcinctus	95.31	5.00e-143	499.00
IUUC-Dor-031029	Dipodomys ordii	87.89	1.00e-125	442.00
IUUC-Dse-031275	Dothistroma septosporum	29.26	2.00e-18	86.30
IUUC-Dme-031856	Drosophila melanogaster	55.69	7.00e-81	293.00
IUUC-Ete-033087	Echinops telfairi	90.22	2.00e-116	411.00
IUUC-Eca-033512	Equus caballus	95.31	2.00e-142	498.00
IUUC-Eeu-034763	Erinaceus europaeus	89.47	3.00e-95	340.00
IUUC-Fca-036460	Felis catus	90.07	5.00e-144	503.00
IUUC-Fal-037441	Ficedula albicollis	86.38	2.00e-128	451.00
IUUC-Fox-038028	Fusarium oxysporum	29.15	3.00e-30	125.00
IUUC-Fso-038323	Fusarium solani	30.98	2.00e-22	99.00
IUUC-Gmo-038511	Gadus morhua	75.39	6.00e-112	396.00
IUUC-Ggr-039964	Gaeumannomyces graminis	32.05	1.00e-19	90.10
IUUC-Gga-040854	Gallus gallus	86.77	9.00e-129	452.00
IUUC-Gac-042175	Gasterosteus aculeatus	75.39	2.00e-108	385.00
IUUC-Gma-044046	Glycine max	35.29	2.00e-35	142.00
IUUC-Ggo-044512	Gorilla gorilla	92.97	1.00e-134	472.00
IUUC-Hsa-046872	Homo sapiens	92.97	1.00e-134	472.00
IUUC-Hvu-047661	Hordeum vulgare	34.92	2.00e-32	132.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	93.75	2.00e-140	491.00
IUUC-Lch-049988	Latimeria chalumnae	80.86	2.00e-114	404.00
IUUC-Lpe-050693	Leersia perrieri	33.73	2.00e-35	142.00
IUUC-Loc-052195	Lepisosteus oculatus	77.69	1.00e-114	405.00
IUUC-Lma-053207	Leptosphaeria maculans	30.28	4.00e-21	96.70
IUUC-Laf-054584	Loxodonta africana	94.14	4.00e-142	496.00
IUUC-Mcc-054689	Macaca mulatta	92.97	1.00e-134	472.00
IUUC-Meu-055998	Macropus eugenii	82.01	4.00e-61	228.00
IUUC-Mor-057116	Magnaporthe oryzae	32.56	4.00e-29	121.00
IUUC-Mtr-057684	Medicago truncatula	31.62	3.00e-32	131.00
IUUC-Mga-059332	Meleagris gallopavo	86.77	1.00e-128	451.00
IUUC-Mmr-061377	Microcebus murinus	92.19	5.00e-133	466.00
IUUC-Mdo-061963	Monodelphis domestica	83.58	2.00e-125	441.00
IUUC-Mmu-063146	Mus musculus	91.80	3.00e-132	464.00
IUUC-Mac-064932	Musa acuminata	44.35	2.00e-27	115.00
IUUC-Mpu-066418	Mustela putorius furo	96.09	1.00e-143	502.00
IUUC-Mlu-067066	Myotis lucifugus	96.09	6.00e-144	503.00
IUUC-Nfi-068601	Neosartorya fischeri	29.81	2.00e-26	112.00
IUUC-Ncr-068761	Neurospora crassa	41.67	1.00e-16	80.10
IUUC-Nle-069374	Nomascus leucogenys	92.97	1.00e-134	472.00
IUUC-Opr-070765	Ochotona princeps	88.36	2.00e-98	351.00
IUUC-Ont-071996	Oreochromis niloticus	78.52	2.00e-112	398.00
IUUC-Oba-075967	Oryza barthii	35.97	9.00e-37	146.00
IUUC-Obr-076440	Oryza brachyantha	34.51	5.00e-29	124.00
IUUC-Ogl-076959	Oryza glaberrima	36.22	5.00e-37	147.00
IUUC-Ogu-078247	Oryza glumaepatula	35.50	3.00e-37	148.00
IUUC-Oin-079616	Oryza indica	36.22	5.00e-37	147.00
IUUC-Olo-080492	Oryza longistaminata	33.64	1.00e-27	119.00
IUUC-Ome-081935	Oryza meridionalis	29.08	1.00e-17	86.30
IUUC-Oni-082535	Oryza nivara	35.50	3.00e-37	148.00
IUUC-Opu-083794	Oryza punctata	35.32	4.00e-36	145.00
IUUC-Oru-085166	Oryza rufipogon	35.50	3.00e-37	148.00
IUUC-Osa-085472	Oryza sativa	42.65	2.00e-09	57.00
IUUC-Ola-087081	Oryzias latipes	77.73	2.00e-115	408.00
IUUC-Olu-087790	Ostreococcus lucimarinus	29.96	5.00e-24	104.00
IUUC-Oga-088331	Otolemur garnettii	92.58	2.00e-134	471.00
IUUC-Ptr-090855	Pan troglodytes	92.97	1.00e-134	472.00
IUUC-Pan-092801	Papio anubis	88.67	9.00e-133	466.00
IUUC-Psi-093393	Pelodiscus sinensis	85.00	1.00e-128	451.00
IUUC-Pma-094680	Petromyzon marinus	66.54	9.00e-96	343.00
IUUC-Pno-094913	Phaeosphaeria nodorum	31.94	1.00e-25	110.00
IUUC-Ppa-095976	Physcomitrella patens	33.10	2.00e-35	143.00
IUUC-Pfo-096850	Poecilia formosa	76.17	4.00e-109	387.00
IUUC-Pab-097963	Pongo abelii	92.97	1.00e-134	472.00
IUUC-Pop-098805	Populus trichocarpa	43.88	1.00e-24	105.00
IUUC-Pca-100788	Procavia capensis	94.53	7.00e-143	499.00
IUUC-Ppe-101221	Prunus persica	34.12	2.00e-37	149.00
IUUC-Pva-103076	Pteropus vampyrus	95.31	8.00e-143	499.00
IUUC-Pte-104237	Pyrenophora teres	30.97	3.00e-25	108.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	30.97	2.00e-25	109.00
IUUC-Rno-105204	Rattus norvegicus	91.80	1.00e-132	465.00
IUUC-Sha-106579	Sarcophilus harrisii	87.50	3.00e-127	447.00
IUUC-Smo-109525	Selaginella moellendorffii	33.60	1.00e-33	136.00
IUUC-Sit-110665	Setaria italica	35.46	4.00e-37	148.00
IUUC-Sly-111473	Solanum lycopersicum	35.77	1.00e-36	146.00
IUUC-Stu-112353	Solanum tuberosum	34.51	6.00e-36	144.00
IUUC-Sbi-114250	Sorghum bicolor	36.58	5.00e-38	150.00
IUUC-Ssc-115416	Sus scrofa	95.31	5.00e-143	499.00
IUUC-Tgu-117272	Taeniopygia guttata	94.44	1.00e-56	210.00
IUUC-Tru-117777	Takifugu rubripes	76.95	5.00e-111	393.00
IUUC-Tni-120572	Tetraodon nigroviridis	77.34	2.00e-111	394.00
IUUC-Tca-121149	Theobroma cacao	36.08	3.00e-41	161.00
IUUC-Tre-122230	Trichoderma reesei	41.18	3.00e-16	78.60
IUUC-Tvi-122678	Trichoderma virens	34.11	4.00e-35	141.00
IUUC-Tae-122986	Triticum aestivum	33.97	8.00e-36	143.00
IUUC-Tur-126009	Triticum urartu	33.21	2.00e-34	139.00
IUUC-Tme-126948	Tuber melanosporum	36.25	3.00e-36	144.00
IUUC-Ttr-129031	Tursiops truncatus	95.70	3.00e-143	500.00
IUUC-Vda-130023	Verticillium dahliae	31.45	6.00e-29	120.00
IUUC-Vvi-131091	Vitis vinifera	40.80	8.00e-25	105.00
IUUC-Xtr-132871	Xenopus tropicalis	79.69	3.00e-112	397.00
IUUC-Xma-134220	Xiphophorus maculatus	76.17	5.00e-109	386.00
IUUC-Yli-134462	Yarrowia lipolytica	27.41	5.00e-21	94.70
IUUC-Zma-135773	Zea mays	36.22	4.00e-39	154.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence