iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071265

Ensembl Protein ID

ENSONIP00000025640.1

UniProt Accession

I3KWZ4; I3KWZ4_ORENI

Genbank Protein ID

ENSONIP00000025640

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01008671

Gene Name

uba3; LOC100707169

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000020345.1	ENSONIT00000025661.1	ENSONIP00000025640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.30e-92	309.3	63	254

Active Site

Position(s)	Description	Evidence
236	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 13   qeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitele 101
           q  l+++k+l++GagglGcEllKnL+l+G+++i+vvDmd ++vsnlnrqFLfra+dvg++KA+vaa++++ ++p + v ++ ++i++l+
   Q: 63   QFMLETCKILVIGAGGLGCELLKNLALSGFRNIHVVDMDNIDVSNLNRQFLFRAKDVGRPKADVAADFINSRVPGCCVIPYFKKIQDLD 151
           6679************************************************************************************* PP
   S: 102  eeivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctl 176
           e+  F+++f+++v++ld++ arr++n ++l++             +pli++gt+G++G++rvi++g+t+c++c+   +ppq ++P+ct+
   Q: 152  ET--FYRQFHIIVCGLDSIVARRWMNGMLLSLlvyedgvldpssIIPLIDGGTEGFKGNARVILPGMTACIDCTLelYPPQINFPMCTI 238
           **..************************************************************************************* PP
   S: 177  ketpnaaehtiewavl 192
           +++p+ +eh+ie++++
   Q: 239  ASMPRLPEHCIEYVRI 254
           *************943 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAETDEPEKK RRRVVELTEK MLVDGDAGST SDWDDRWNHI KKFLERSGPF MHPDFEPSTE 60
SLQFMLETCK ILVIGAGGLG CELLKNLALS GFRNIHVVDM DNIDVSNLNR QFLFRAKDVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTACTCAAA GATGGCGGAG ACGGACGAGC CGTAAGTAGC TGCTGAAGAA ACAAGCAAGA 60
AACCCCGAAA GATGCTTTCA AGTCACCTTA ATCTGCGAAA GCACAGCATG AATCAACCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afl-008615	Aspergillus flavus	43.33	4.00e-77	281.00
IUUC-Ang-009539	Aspergillus niger	51.76	9.00e-113	400.00
IUUC-Aor-010151	Aspergillus oryzae	48.11	6.00e-108	384.00
IUUC-Cho-025052	Choloepus hoffmanni	76.24	0.00e+00	716.00
IUUC-Dre-028751	Danio rerio	86.77	0.00e+00	800.00
IUUC-Dse-031329	Dothistroma septosporum	47.82	5.00e-105	374.00
IUUC-Gmo-039647	Gadus morhua	85.50	0.00e+00	811.00
IUUC-Gac-042601	Gasterosteus aculeatus	88.53	0.00e+00	838.00
IUUC-Lch-049471	Latimeria chalumnae	84.30	0.00e+00	783.00
IUUC-Ola-086615	Oryzias latipes	83.33	0.00e+00	780.00
IUUC-Pma-094247	Petromyzon marinus	80.89	0.00e+00	751.00
IUUC-Pfo-096846	Poecilia formosa	85.75	0.00e+00	820.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence