iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004613

UUCD1 version

UUC-AnC-00266

Ensembl Protein ID

ENSACAP00000013495.2

UniProt Accession

H9GK81; H9GK81_ANOCA

Protein Name

Uncharacterized protein

Gene Name

MLST8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013727.2	ENSACAT00000013773.2	ENSACAP00000013495.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-32	110.5	280	310
UBD/Beta-Prp	1.60e-44	152.2	281	383

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H+     ++f +d tll+++s D t+k+W++
   Q: 280  HNRYALQCKFsPDsTLLATCSADQTCKIWRT 310
           6667778899*999***************96 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae........vtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
             +    kfspd++llat s+d+t k+w++++ +l+ +ls +++          +++ fs d++++vt+s+D+++++w ++tg++ + +
   Q: 281  NRYALQCKFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSNNpgetsrgwMWDCAFSGDSQYIVTASSDNLARLWCVETGEIKREY 369
           4444457999**********************9999999655555569999999********99************************* PP
   S: 91   kghedsvlslsfsp 104
           +gh++ v++l+f+ 
   Q: 370  SGHQKAVVCLAFND 383
           *********99986 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MRTGFLFAHE HLALDGCSCA HAPWQSCSWS ACLPSNPSFS SEGKEIGILP FDKSIGNGPG 60
GMNTAQGTVG SDPVILATAG YDHTVRFWQA HSGICTRTVQ HQDSQVNALE ITPDRTMIAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAATCTG AAGGCTCTTC TGCGCATGCG GACTGGCTTT CTCTTTGCGC ATGAGCACTT 60
GGCACTCGAT GGATGCTCGT GTGCGCATGC GCCCTGGCAG TCTTGTTCCT GGTCTGCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0031931--C:TORC1 complex
GO:0031932--C:TORC2 complex
GO:0043539--F:protein serine/threonine kinase activator activity
GO:0030838--P:positive regulation of actin filament polymerization
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0032008--P:positive regulation of TOR signaling
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity
GO:0031929--P:TOR signaling
GO:0038202--P:TORC1 signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000595	Aegilops tauschii	49.52	2.00e-85	308.00
IUUC-Aml-001813	Ailuropoda melanoleuca	93.87	0.00e+00	648.00
IUUC-Atr-002512	Amborella trichopoda	47.94	2.00e-81	295.00
IUUC-Apl-003495	Anas platyrhynchos	95.42	2.00e-159	554.00
IUUC-Aly-006340	Arabidopsis lyrata	46.95	4.00e-81	294.00
IUUC-Ath-007273	Arabidopsis thaliana	46.62	2.00e-80	291.00
IUUC-Ago-007737	Ashbya gossypii	47.44	3.00e-82	298.00
IUUC-Acl-008090	Aspergillus clavatus	49.79	4.00e-60	224.00
IUUC-Afl-008490	Aspergillus flavus	43.37	8.00e-41	160.00
IUUC-Afu-009060	Aspergillus fumigatus	47.77	2.00e-53	202.00
IUUC-Ani-009251	Aspergillus nidulans	49.58	2.00e-60	225.00
IUUC-Ang-009528	Aspergillus niger	46.89	4.00e-77	281.00
IUUC-Aor-010005	Aspergillus oryzae	45.72	2.00e-70	258.00
IUUC-Ate-010423	Aspergillus terreus	50.21	2.00e-60	226.00
IUUC-Ame-011752	Astyanax mexicanus	96.63	0.00e+00	665.00
IUUC-Bgr-012299	Blumeria graminis	44.05	6.00e-73	267.00
IUUC-Bta-013007	Bos taurus	94.38	0.00e+00	640.00
IUUC-Bci-013987	Botrytis cinerea	45.23	3.00e-78	285.00
IUUC-Bdi-014082	Brachypodium distachyon	49.84	1.00e-85	309.00
IUUC-Bol-015088	Brassica oleracea	47.27	4.00e-81	294.00
IUUC-Bra-016682	Brassica rapa	41.02	6.00e-70	257.00
IUUC-Cel-018473	Caenorhabditis elegans	25.89	5.00e-38	151.00
IUUC-Cja-019216	Callithrix jacchus	93.63	1.00e-151	528.00
IUUC-Cfa-021229	Canis familiaris	94.17	0.00e+00	651.00
IUUC-Cpo-022270	Cavia porcellus	94.48	0.00e+00	653.00
IUUC-Cre-022742	Chlamydomonas reinhardtii	49.84	2.00e-87	315.00
IUUC-Csa-023275	Chlorocebus sabaeus	94.48	0.00e+00	652.00
IUUC-Cin-025588	Ciona intestinalis	65.08	1.00e-130	458.00
IUUC-Csv-026252	Ciona savignyi	66.25	1.00e-133	468.00
IUUC-Cgl-026418	Colletotrichum gloeosporioides	47.13	1.00e-77	283.00
IUUC-Cne-027013	Cryptococcus neoformans	43.13	1.00e-72	266.00
IUUC-Cme-027131	Cyanidioschyzon merolae	31.89	7.00e-51	194.00
IUUC-Dre-028424	Danio rerio	96.32	0.00e+00	664.00
IUUC-Dno-029327	Dasypus novemcinctus	94.17	0.00e+00	651.00
IUUC-Dor-030186	Dipodomys ordii	95.00	2.00e-90	325.00
IUUC-Dse-031475	Dothistroma septosporum	45.48	4.00e-76	277.00
IUUC-Dme-031826	Drosophila melanogaster	51.11	2.00e-96	345.00
IUUC-Ete-032252	Echinops telfairi	80.69	8.00e-135	472.00
IUUC-Eca-033889	Equus caballus	94.51	1.00e-134	471.00
IUUC-Fca-035989	Felis catus	93.87	0.00e+00	650.00
IUUC-Fal-036637	Ficedula albicollis	98.77	0.00e+00	676.00
IUUC-Fox-038066	Fusarium oxysporum	48.09	6.00e-81	293.00
IUUC-Fso-038288	Fusarium solani	45.86	6.00e-75	273.00
IUUC-Gmo-039477	Gadus morhua	95.11	0.00e+00	656.00
IUUC-Ggr-039990	Gaeumannomyces graminis	47.48	3.00e-77	281.00
IUUC-Gga-040890	Gallus gallus	99.08	0.00e+00	678.00
IUUC-Gac-041502	Gasterosteus aculeatus	96.32	0.00e+00	663.00
IUUC-Gma-042985	Glycine max	48.25	3.00e-82	298.00
IUUC-Ggo-045629	Gorilla gorilla	93.90	0.00e+00	647.00
IUUC-Hsa-045824	Homo sapiens	93.40	2.00e-164	570.00
IUUC-Hvu-047767	Hordeum vulgare	49.84	1.00e-85	309.00
IUUC-Itr-047932	Ictidomys tridecemlineatus	94.48	0.00e+00	653.00
IUUC-Kpa-049173	Komagataella pastoris	47.12	4.00e-83	300.00
IUUC-Lch-049703	Latimeria chalumnae	98.47	0.00e+00	673.00
IUUC-Lpe-050744	Leersia perrieri	45.40	6.00e-74	270.00
IUUC-Loc-052507	Lepisosteus oculatus	96.32	0.00e+00	662.00
IUUC-Lma-053084	Leptosphaeria maculans	45.29	3.00e-73	268.00
IUUC-Laf-053595	Loxodonta africana	93.87	0.00e+00	648.00
IUUC-Mcc-055634	Macaca mulatta	80.74	8.00e-178	615.00
IUUC-Meu-055925	Macropus eugenii	96.88	1.00e-169	588.00
IUUC-Mor-057131	Magnaporthe oryzae	44.48	2.00e-78	285.00
IUUC-Mpo-057524	Magnaporthe poae	47.80	6.00e-78	283.00
IUUC-Mtr-057980	Medicago truncatula	48.25	8.00e-83	300.00
IUUC-Mla-059082	Melampsora laricipopulina	40.46	4.00e-63	234.00
IUUC-Mga-059552	Meleagris gallopavo	96.47	2.00e-161	560.00
IUUC-Mvi-060504	Microbotryum violaceum	44.38	4.00e-71	262.00
IUUC-Mdo-062886	Monodelphis domestica	97.24	0.00e+00	668.00
IUUC-Mmu-063477	Mus musculus	94.17	0.00e+00	650.00
IUUC-Mac-065439	Musa acuminata	48.89	1.00e-83	302.00
IUUC-Mpu-066708	Mustela putorius furo	93.87	0.00e+00	648.00
IUUC-Mlu-067311	Myotis lucifugus	91.10	0.00e+00	639.00
IUUC-Nfi-068294	Neosartorya fischeri	47.58	9.00e-54	203.00
IUUC-Ncr-068811	Neurospora crassa	45.08	2.00e-75	275.00
IUUC-Nle-069632	Nomascus leucogenys	94.48	0.00e+00	652.00
IUUC-Opr-071128	Ochotona princeps	93.72	2.00e-106	377.00
IUUC-Ont-071494	Oreochromis niloticus	96.63	0.00e+00	667.00
IUUC-Oan-073298	Ornithorhynchus anatinus	94.71	5.00e-106	375.00
IUUC-Ocu-073983	Oryctolagus cuniculus	93.87	0.00e+00	647.00
IUUC-Oba-076001	Oryza barthii	44.76	3.00e-73	268.00
IUUC-Obr-076833	Oryza brachyantha	48.25	3.00e-82	298.00
IUUC-Ogl-077680	Oryza glaberrima	47.94	6.00e-82	296.00
IUUC-Ogu-078086	Oryza glumaepatula	44.76	3.00e-73	268.00
IUUC-Oin-079336	Oryza indica	47.94	6.00e-82	296.00
IUUC-Olo-080368	Oryza longistaminata	42.61	1.00e-59	222.00
IUUC-Oni-083046	Oryza nivara	44.76	3.00e-73	268.00
IUUC-Opu-084173	Oryza punctata	44.76	3.00e-73	268.00
IUUC-Oru-084599	Oryza rufipogon	44.76	3.00e-73	268.00
IUUC-Osa-086193	Oryza sativa	47.94	6.00e-82	296.00
IUUC-Ola-087216	Oryzias latipes	96.63	0.00e+00	666.00
IUUC-Olu-087852	Ostreococcus lucimarinus	48.57	7.00e-84	303.00
IUUC-Oga-088840	Otolemur garnettii	93.60	0.00e+00	647.00
IUUC-Oar-089294	Ovis aries	93.43	2.00e-164	571.00
IUUC-Ptr-090565	Pan troglodytes	94.48	0.00e+00	652.00
IUUC-Pan-092175	Papio anubis	94.48	0.00e+00	652.00
IUUC-Psi-093180	Pelodiscus sinensis	99.63	2.00e-163	567.00
IUUC-Pma-094705	Petromyzon marinus	84.36	8.00e-173	598.00
IUUC-Pno-095001	Phaeosphaeria nodorum	42.95	5.00e-63	234.00
IUUC-Ppa-095628	Physcomitrella patens	49.52	7.00e-86	310.00
IUUC-Pfo-097128	Poecilia formosa	96.32	0.00e+00	665.00
IUUC-Pab-098386	Pongo abelii	94.48	0.00e+00	652.00
IUUC-Pop-099064	Populus trichocarpa	48.89	2.00e-83	301.00
IUUC-Pca-100971	Procavia capensis	93.06	3.00e-164	570.00
IUUC-Ppe-101871	Prunus persica	48.57	9.00e-83	299.00
IUUC-Pva-102230	Pteropus vampyrus	74.49	4.00e-126	444.00
IUUC-Pgr-103511	Puccinia graminis	42.15	2.00e-66	246.00
IUUC-Ptt-103882	Puccinia triticina	38.95	1.00e-63	236.00
IUUC-Pte-104402	Pyrenophora teres	45.59	8.00e-74	270.00
IUUC-Pyt-104448	Pyrenophora triticirepentis	45.59	9.00e-74	270.00
IUUC-Rno-104880	Rattus norvegicus	94.17	0.00e+00	650.00
IUUC-Sce-106266	Saccharomyces cerevisiae	47.76	1.00e-83	303.00
IUUC-Sha-106966	Sarcophilus harrisii	97.24	0.00e+00	668.00
IUUC-Sja-107797	Schizosaccharomyces japonicus	48.23	2.00e-86	311.00
IUUC-Spo-108366	Schizosaccharomyces pombe	46.62	4.00e-85	307.00
IUUC-Smo-108749	Selaginella moellendorffii	48.42	2.00e-81	295.00
IUUC-Sit-110741	Setaria italica	49.84	1.00e-84	306.00
IUUC-Sly-111879	Solanum lycopersicum	42.86	2.00e-50	191.00
IUUC-Sbi-114551	Sorghum bicolor	49.84	1.00e-84	306.00
IUUC-Sre-114962	Sporisorium reilianum	39.39	3.00e-74	272.00
IUUC-Ssc-115363	Sus scrofa	93.60	0.00e+00	647.00
IUUC-Tgu-116695	Taeniopygia guttata	81.29	1.00e-148	518.00
IUUC-Tru-117999	Takifugu rubripes	94.82	0.00e+00	657.00
IUUC-Tni-119973	Tetraodon nigroviridis	95.40	0.00e+00	663.00
IUUC-Tca-121688	Theobroma cacao	48.42	1.00e-82	299.00
IUUC-Tre-122158	Trichoderma reesei	43.81	1.00e-75	276.00
IUUC-Tvi-122511	Trichoderma virens	46.08	4.00e-77	280.00
IUUC-Tae-124124	Triticum aestivum	49.52	2.00e-85	308.00
IUUC-Tur-126228	Triticum urartu	46.67	9.00e-77	279.00
IUUC-Tme-127100	Tuber melanosporum	48.87	2.00e-86	311.00
IUUC-Ttr-128216	Tursiops truncatus	93.81	1.00e-51	196.00
IUUC-Uma-129358	Ustilago maydis	40.34	1.00e-75	276.00
IUUC-Vda-129756	Verticillium dahliae	46.35	2.00e-78	285.00
IUUC-Vvi-131581	Vitis vinifera	46.67	5.00e-80	290.00
IUUC-Xtr-132363	Xenopus tropicalis	94.48	0.00e+00	651.00
IUUC-Xma-133857	Xiphophorus maculatus	96.32	0.00e+00	665.00
IUUC-Yli-134368	Yarrowia lipolytica	47.44	2.00e-81	295.00
IUUC-Zma-135854	Zea mays	49.84	7.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence