iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037361

Ensembl Protein ID

ENSFALP00000009778.1

UniProt Accession

U3K424; U3K424_FICAL

Genbank Protein ID

ENSFALP00000009778

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010333

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000009356.1	ENSFALT00000009818.1	ENSFALP00000009778.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-38	129.3	190	227
UBD/Beta-Prp	3.00e-61	206.9	57	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           Ht  v+c++f +d ++++++s Dg+i v+D +tg +++
   Q: 190  HTRFVNCVRFsPDgNRFATASADGQIFVYDGKTGEKVC 227
           9999*******999****************99998765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           ++h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++
   Q: 57   TEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDLAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEIT 145
           4566667778*************************998777742334567***********99999999887777777789******** PP
   S: 92   ghedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tg 177
           gh++ + s+++ +++ ++l++Gs+d+ +  ++ +  +    tls h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   +
   Q: 146  GHNKVINSVDIKQTRpYRLATGSDDNCAAFFEGPPFKFKF-TLSDHTRFVNCVRFSPDGNRFATASADGQIFVYDGKTGEKVCALggDK 233
           *************999*******************99999.********************************************9966 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdn 224
           +h++ +y +s+++++ +l+s+s d+t k+wd+ ++++v+t+n  ++ 
   Q: 234  AHDGGIYAISWSPDSSQLLSASGDKTAKIWDVGANSIVNTFNMGSNV 280
           7****************************************976654 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

FSFYFSVEKV FASLPQVERG VSKIIGGDPK GNNFLYTNGK CVIIRNIDNP AIADIYTEHA 60
HQVVVAKYAP SGFYIASGDV SGKLRIWDTT QKEHLLKYEY QPFAGKIKDL AWTEDSKRIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCGTTAAG CGCCTGCCTT TTATTTTGAT CTCTTAAAAA AATATTTTTA AAATTACTTT 60
TACTGTGATA TATTTTCCTT TTATTCCCTT TCTCCTTTTA TTTTTCCGTA GAAAAAGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	36.13	1.00e-84	306.00
IUUC-Aml-002368	Ailuropoda melanoleuca	88.58	0.00e+00	1105.00
IUUC-Atr-003160	Amborella trichopoda	38.05	3.00e-117	415.00
IUUC-Apl-004012	Anas platyrhynchos	94.71	0.00e+00	1154.00
IUUC-Aca-004707	Anolis carolinensis	84.25	0.00e+00	1060.00
IUUC-Aly-006465	Arabidopsis lyrata	38.74	4.00e-116	411.00
IUUC-Ath-006740	Arabidopsis thaliana	38.57	1.00e-114	406.00
IUUC-Ago-007920	Ashbya gossypii	27.59	2.00e-74	273.00
IUUC-Acl-008262	Aspergillus clavatus	36.05	2.00e-107	382.00
IUUC-Afl-008471	Aspergillus flavus	33.78	5.00e-80	291.00
IUUC-Afu-008989	Aspergillus fumigatus	37.77	2.00e-96	345.00
IUUC-Ani-009167	Aspergillus nidulans	37.42	4.00e-115	408.00
IUUC-Ang-009595	Aspergillus niger	38.08	2.00e-103	369.00
IUUC-Aor-009908	Aspergillus oryzae	35.96	1.00e-102	367.00
IUUC-Ate-010580	Aspergillus terreus	37.50	2.00e-108	387.00
IUUC-Ame-011269	Astyanax mexicanus	61.71	5.00e-134	471.00
IUUC-Bgr-011996	Blumeria graminis	34.15	1.00e-106	380.00
IUUC-Bta-013278	Bos taurus	88.93	0.00e+00	1139.00
IUUC-Bci-013925	Botrytis cinerea	35.50	5.00e-108	384.00
IUUC-Bdi-014659	Brachypodium distachyon	35.47	4.00e-105	375.00
IUUC-Bol-016043	Brassica oleracea	37.21	3.00e-113	402.00
IUUC-Bra-017139	Brassica rapa	37.50	3.00e-113	402.00
IUUC-Cel-018417	Caenorhabditis elegans	40.56	1.00e-123	436.00
IUUC-Cja-019952	Callithrix jacchus	86.78	0.00e+00	1076.00
IUUC-Cfa-020225	Canis familiaris	88.26	0.00e+00	1110.00
IUUC-Cpo-021900	Cavia porcellus	87.38	0.00e+00	1102.00
IUUC-Csa-023028	Chlorocebus sabaeus	87.60	0.00e+00	1084.00
IUUC-Cho-025030	Choloepus hoffmanni	65.06	0.00e+00	721.00
IUUC-Cin-025152	Ciona intestinalis	54.26	2.00e-80	291.00
IUUC-Csv-025986	Ciona savignyi	37.90	1.00e-92	333.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.30	4.00e-113	401.00
IUUC-Cne-026814	Cryptococcus neoformans	35.18	4.00e-99	355.00
IUUC-Dre-027498	Danio rerio	80.31	3.00e-95	340.00
IUUC-Dno-029383	Dasypus novemcinctus	86.94	0.00e+00	1070.00
IUUC-Dor-030633	Dipodomys ordii	86.27	0.00e+00	1021.00
IUUC-Dse-031526	Dothistroma septosporum	38.51	1.00e-114	407.00
IUUC-Dme-031597	Drosophila melanogaster	48.01	2.00e-170	592.00
IUUC-Ete-032780	Echinops telfairi	82.40	0.00e+00	1003.00
IUUC-Eca-034306	Equus caballus	86.86	0.00e+00	1080.00
IUUC-Eeu-034531	Erinaceus europaeus	69.57	5.00e-129	454.00
IUUC-Fca-036301	Felis catus	88.70	0.00e+00	1132.00
IUUC-Fox-037924	Fusarium oxysporum	34.80	8.00e-101	360.00
IUUC-Fso-038199	Fusarium solani	34.15	2.00e-97	349.00
IUUC-Gmo-039238	Gadus morhua	71.95	0.00e+00	890.00
IUUC-Ggr-039830	Gaeumannomyces graminis	34.77	7.00e-97	347.00
IUUC-Gga-040235	Gallus gallus	95.54	0.00e+00	1176.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.85	0.00e+00	928.00
IUUC-Gma-044189	Glycine max	38.24	2.00e-117	416.00
IUUC-Ggo-044632	Gorilla gorilla	85.62	0.00e+00	1055.00
IUUC-Hsa-045792	Homo sapiens	87.11	0.00e+00	1097.00
IUUC-Hvu-047517	Hordeum vulgare	35.78	5.00e-110	391.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	88.08	0.00e+00	1101.00
IUUC-Kpa-049183	Komagataella pastoris	33.11	2.00e-87	315.00
IUUC-Lch-050428	Latimeria chalumnae	77.23	0.00e+00	1009.00
IUUC-Lpe-051306	Leersia perrieri	36.17	2.00e-111	396.00
IUUC-Loc-052096	Lepisosteus oculatus	72.85	0.00e+00	905.00
IUUC-Lma-053313	Leptosphaeria maculans	38.76	2.00e-117	418.00
IUUC-Laf-054060	Loxodonta africana	86.28	0.00e+00	1083.00
IUUC-Mcc-055619	Macaca mulatta	86.54	0.00e+00	1066.00
IUUC-Meu-056689	Macropus eugenii	76.57	6.00e-180	623.00
IUUC-Mor-056940	Magnaporthe oryzae	35.55	3.00e-98	352.00
IUUC-Mpo-057557	Magnaporthe poae	30.52	1.00e-70	260.00
IUUC-Mtr-058478	Medicago truncatula	37.42	6.00e-115	407.00
IUUC-Mla-059103	Melampsora laricipopulina	33.57	1.00e-78	286.00
IUUC-Mga-060150	Meleagris gallopavo	95.87	0.00e+00	1177.00
IUUC-Mvi-060448	Microbotryum violaceum	31.13	8.00e-77	281.00
IUUC-Mmr-061226	Microcebus murinus	86.28	0.00e+00	1080.00
IUUC-Mdo-062674	Monodelphis domestica	89.42	0.00e+00	1128.00
IUUC-Mmu-064170	Mus musculus	87.44	0.00e+00	1106.00
IUUC-Mac-065124	Musa acuminata	38.95	3.00e-116	412.00
IUUC-Mpu-066001	Mustela putorius furo	84.87	0.00e+00	1087.00
IUUC-Mlu-067253	Myotis lucifugus	88.35	0.00e+00	1111.00
IUUC-Nfi-068550	Neosartorya fischeri	37.85	2.00e-110	393.00
IUUC-Ncr-068948	Neurospora crassa	35.91	8.00e-112	397.00
IUUC-Nle-070115	Nomascus leucogenys	83.83	0.00e+00	995.00
IUUC-Opr-070254	Ochotona princeps	85.69	0.00e+00	1040.00
IUUC-Ont-071666	Oreochromis niloticus	76.20	0.00e+00	964.00
IUUC-Oan-073594	Ornithorhynchus anatinus	87.16	1.00e-158	551.00
IUUC-Ocu-074824	Oryctolagus cuniculus	85.79	0.00e+00	1054.00
IUUC-Oba-075010	Oryza barthii	36.33	1.00e-111	396.00
IUUC-Obr-076364	Oryza brachyantha	38.01	4.00e-114	405.00
IUUC-Ogl-077019	Oryza glaberrima	36.33	1.00e-111	396.00
IUUC-Ogu-078496	Oryza glumaepatula	36.33	1.00e-111	396.00
IUUC-Oin-080116	Oryza indica	36.50	8.00e-112	397.00
IUUC-Olo-080290	Oryza longistaminata	36.39	2.00e-111	395.00
IUUC-Ome-081969	Oryza meridionalis	36.33	2.00e-111	396.00
IUUC-Oni-082075	Oryza nivara	36.33	1.00e-111	396.00
IUUC-Opu-083959	Oryza punctata	36.50	6.00e-112	397.00
IUUC-Oru-084711	Oryza rufipogon	36.33	1.00e-111	396.00
IUUC-Osa-085958	Oryza sativa	36.50	8.00e-112	397.00
IUUC-Ola-086968	Oryzias latipes	75.54	0.00e+00	963.00
IUUC-Oga-089108	Otolemur garnettii	87.03	0.00e+00	1127.00
IUUC-Oar-089986	Ovis aries	83.69	0.00e+00	1056.00
IUUC-Ptr-091281	Pan troglodytes	88.02	0.00e+00	1099.00
IUUC-Pan-092585	Papio anubis	87.60	0.00e+00	1083.00
IUUC-Psi-093811	Pelodiscus sinensis	91.38	0.00e+00	1163.00
IUUC-Pma-094542	Petromyzon marinus	70.72	0.00e+00	904.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.08	2.00e-111	395.00
IUUC-Ppa-095876	Physcomitrella patens	36.57	2.00e-113	402.00
IUUC-Pfo-096973	Poecilia formosa	76.53	0.00e+00	1003.00
IUUC-Pab-098391	Pongo abelii	87.11	0.00e+00	1081.00
IUUC-Pop-098850	Populus trichocarpa	38.24	2.00e-116	412.00
IUUC-Pca-100257	Procavia capensis	57.24	3.00e-87	315.00
IUUC-Ppe-101578	Prunus persica	39.05	2.00e-118	419.00
IUUC-Pva-102872	Pteropus vampyrus	82.98	0.00e+00	1060.00
IUUC-Pgr-103593	Puccinia graminis	33.33	4.00e-83	301.00
IUUC-Pte-104365	Pyrenophora teres	38.93	9.00e-113	400.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.60	2.00e-115	409.00
IUUC-Rno-105737	Rattus norvegicus	87.77	0.00e+00	1127.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.46	1.00e-68	253.00
IUUC-Sha-107084	Sarcophilus harrisii	87.17	0.00e+00	994.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.94	3.00e-113	402.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.22	4.00e-95	341.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.19	5.00e-108	384.00
IUUC-Smo-109255	Selaginella moellendorffii	36.79	7.00e-106	377.00
IUUC-Sit-109962	Setaria italica	37.17	6.00e-114	404.00
IUUC-Sly-110897	Solanum lycopersicum	39.18	4.00e-119	421.00
IUUC-Stu-111971	Solanum tuberosum	38.69	2.00e-117	416.00
IUUC-Sar-113415	Sorex araneus	70.48	1.00e-107	383.00
IUUC-Sbi-114857	Sorghum bicolor	36.62	2.00e-111	395.00
IUUC-Sre-114900	Sporisorium reilianum	35.55	2.00e-93	336.00
IUUC-Tgu-117256	Taeniopygia guttata	98.01	0.00e+00	1224.00
IUUC-Tru-117871	Takifugu rubripes	72.07	0.00e+00	910.00
IUUC-Tsy-119172	Tarsius syrichta	92.08	2.00e-134	471.00
IUUC-Tni-120339	Tetraodon nigroviridis	71.66	0.00e+00	935.00
IUUC-Tca-121609	Theobroma cacao	37.40	3.00e-113	402.00
IUUC-Tre-122076	Trichoderma reesei	35.41	3.00e-96	345.00
IUUC-Tvi-122528	Trichoderma virens	34.31	6.00e-98	351.00
IUUC-Tae-125412	Triticum aestivum	36.17	9.00e-111	394.00
IUUC-Tur-126845	Triticum urartu	35.31	1.00e-82	300.00
IUUC-Tme-127217	Tuber melanosporum	35.54	7.00e-105	374.00
IUUC-Tbe-127526	Tupaia belangeri	85.90	0.00e+00	1084.00
IUUC-Ttr-128898	Tursiops truncatus	80.33	0.00e+00	1025.00
IUUC-Uma-129631	Ustilago maydis	32.90	2.00e-93	336.00
IUUC-Vda-129732	Verticillium dahliae	35.46	1.00e-94	340.00
IUUC-Vvi-131217	Vitis vinifera	38.73	2.00e-115	409.00
IUUC-Xtr-132860	Xenopus tropicalis	74.47	0.00e+00	956.00
IUUC-Xma-133830	Xiphophorus maculatus	76.53	0.00e+00	1004.00
IUUC-Yli-134335	Yarrowia lipolytica	32.46	4.00e-72	265.00
IUUC-Zma-135907	Zea mays	36.62	7.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence