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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Sce-106427
Ensembl Protein ID YHR200W
UniProt Accession P38886; D3DLE9; RPN10_YEAST
Genbank Protein ID BAA11207.1; AAB68355.1; AAS56615.1; DAA06893.1
Protein Name 26S proteasome regulatory subunit RPN10
Genbank Nucleotide ID D78022; U00030; AY558289; BK006934
Gene Name RPN10; MCB1; SUN1; YHR200W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YHR200W YHR200W YHR200W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDB
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMBioGRID
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UIM UIM 15242647; 17644757
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UIM 0.0032 16.0 224 242
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqEeees 20
    d+eL++Al+lS++Ee+++
   Q: 224 MDPELAMALRLSMEEEQQR 242
    599*************985 PP
   

Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description



     The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively (By similarity).
The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively (By similarity).
Protein Sequence
(Fasta)
MVLEATVLVI DNSEYSRNGD FPRTRFEAQI DSVEFIFQAK RNSNPENTVG LISGAGANPR 60
VLSTFTAEFG KILAGLHDTQ IEGKLHMATA LQIAQLTLKH RQNKVQHQRI VAFVCSPISD 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Sce-106427|UBD,UIM|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTATTGG AAGCTACAGT GTTAGTGATT GATAATTCAG AGTACTCTCG CAATGGCGAC 60
TTTCCTAGGA CAAGGTTTGA AGCCCAGATC GACTCGGTAG AGTTCATATT TCAAGCCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Sce-106427|UBD,UIM|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0647--Proteasome
KW-1185--Reference proteome

Interpro

IPR027040--Proteasome_su_Rpn10
IPR003903--UIM_dom
IPR002035--VWF_A

PROSITE

PS50330--UIM
PS50234--VWFA

Pfam

PF13519--VWA_2

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000502--C:proteasome complex
GO:0008540--C:proteasome regulatory particle, base subcomplex
GO:0031593--F:polyubiquitin binding
GO:0005198--F:structural molecule activity
GO:0043248--P:proteasome assembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG sce:YHR200W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001241 Ailuropoda melanoleuca 50.00 7.00e-55 205.00
IUUC-Atr-002938 Amborella trichopoda 46.84 3.00e-51 193.00
IUUC-Apl-003881 Anas platyrhynchos 48.87 3.00e-48 182.00
IUUC-Aca-004397 Anolis carolinensis 50.00 3.00e-55 206.00
IUUC-Aly-005564 Arabidopsis lyrata 44.54 1.00e-44 171.00
IUUC-Ath-007436 Arabidopsis thaliana 44.54 2.00e-44 170.00
IUUC-Ago-007858 Ashbya gossypii 76.69 1.00e-104 370.00
IUUC-Acl-008094 Aspergillus clavatus 44.30 1.00e-46 177.00
IUUC-Afl-008689 Aspergillus flavus 45.15 8.00e-48 181.00
IUUC-Afu-008959 Aspergillus fumigatus 45.34 2.00e-46 177.00
IUUC-Ani-009344 Aspergillus nidulans 45.13 9.00e-31 124.00
IUUC-Ang-009602 Aspergillus niger 45.15 4.00e-45 172.00
IUUC-Aor-009906 Aspergillus oryzae 42.78 1.00e-32 130.00
IUUC-Ate-010267 Aspergillus terreus 42.06 2.00e-36 144.00
IUUC-Ame-011018 Astyanax mexicanus 47.74 2.00e-56 211.00
IUUC-Bgr-012200 Blumeria graminis 48.95 1.00e-53 201.00
IUUC-Bta-013066 Bos taurus 50.00 8.00e-55 205.00
IUUC-Bci-013904 Botrytis cinerea 50.63 1.00e-52 197.00
IUUC-Bdi-014537 Brachypodium distachyon 46.84 9.00e-50 188.00
IUUC-Bol-015474 Brassica oleracea 44.54 1.00e-44 171.00
IUUC-Bra-018039 Brassica rapa 44.54 9.00e-45 172.00
IUUC-Cel-018187 Caenorhabditis elegans 36.55 4.00e-30 123.00
IUUC-Cja-019738 Callithrix jacchus 50.00 6.00e-55 206.00
IUUC-Cfa-020362 Canis familiaris 50.00 6.00e-55 205.00
IUUC-Cpo-021297 Cavia porcellus 49.78 4.00e-51 194.00
IUUC-Cre-022783 Chlamydomonas reinhardtii 49.79 3.00e-45 172.00
IUUC-Cho-024800 Choloepus hoffmanni 47.37 4.00e-15 73.60
IUUC-Cin-025469 Ciona intestinalis 45.76 1.00e-43 168.00
IUUC-Csv-026297 Ciona savignyi 47.46 1.00e-51 194.00
IUUC-Cgl-026657 Colletotrichum gloeosporioides 46.67 2.00e-44 170.00
IUUC-Cne-027027 Cryptococcus neoformans 43.88 3.00e-51 193.00
IUUC-Cme-027212 Cyanidioschyzon merolae 40.22 4.00e-39 153.00
IUUC-Dre-027759 Danio rerio 49.58 1.00e-56 211.00
IUUC-Dno-029528 Dasypus novemcinctus 50.00 6.00e-55 206.00
IUUC-Dor-030255 Dipodomys ordii 49.78 1.00e-51 194.00
IUUC-Dse-031464 Dothistroma septosporum 50.63 1.00e-56 211.00
IUUC-Dme-032000 Drosophila melanogaster 41.95 4.00e-44 169.00
IUUC-Ete-032762 Echinops telfairi 49.58 2.00e-54 204.00
IUUC-Eca-034399 Equus caballus 48.51 3.00e-51 194.00
IUUC-Eeu-035072 Erinaceus europaeus 48.86 4.00e-37 146.00
IUUC-Fca-035993 Felis catus 49.78 9.00e-51 191.00
IUUC-Fal-037623 Ficedula albicollis 53.15 6.00e-38 149.00
IUUC-Fox-037746 Fusarium oxysporum 47.08 6.00e-52 195.00
IUUC-Fso-038431 Fusarium solani 48.33 2.00e-55 207.00
IUUC-Gmo-039290 Gadus morhua 49.14 5.00e-52 196.00
IUUC-Ggr-039821 Gaeumannomyces graminis 50.26 2.00e-48 184.00
IUUC-Gga-040288 Gallus gallus 50.42 2.00e-55 207.00
IUUC-Gac-042587 Gasterosteus aculeatus 49.78 1.00e-50 192.00
IUUC-Gma-043225 Glycine max 48.95 2.00e-58 217.00
IUUC-Ggo-044628 Gorilla gorilla 50.00 6.00e-55 206.00
IUUC-Hsa-045850 Homo sapiens 50.00 6.00e-55 205.00
IUUC-Hvu-047715 Hordeum vulgare 47.26 3.00e-50 190.00
IUUC-Itr-048388 Ictidomys tridecemlineatus 49.13 5.00e-52 196.00
IUUC-Kpa-049158 Komagataella pastoris 57.96 1.00e-65 240.00
IUUC-Lch-050472 Latimeria chalumnae 50.22 3.00e-52 197.00
IUUC-Lpe-051233 Leersia perrieri 47.26 1.00e-46 180.00
IUUC-Loc-052437 Lepisosteus oculatus 47.06 2.00e-35 142.00
IUUC-Lma-053295 Leptosphaeria maculans 46.86 5.00e-47 179.00
IUUC-Laf-053504 Loxodonta africana 50.00 6.00e-55 205.00
IUUC-Mcc-054877 Macaca mulatta 50.00 7.00e-55 205.00
IUUC-Meu-056114 Macropus eugenii 49.15 5.00e-54 202.00
IUUC-Mor-057212 Magnaporthe oryzae 47.70 3.00e-51 192.00
IUUC-Mpo-057587 Magnaporthe poae 50.78 1.00e-48 184.00
IUUC-Mtr-058520 Medicago truncatula 49.79 7.00e-54 202.00
IUUC-Mla-059105 Melampsora laricipopulina 50.00 1.00e-24 105.00
IUUC-Mga-059537 Meleagris gallopavo 50.00 2.00e-55 207.00
IUUC-Mvi-060277 Microbotryum violaceum 41.50 2.00e-41 160.00
IUUC-Mmr-061736 Microcebus murinus 50.00 7.00e-55 205.00
IUUC-Mdo-062403 Monodelphis domestica 49.34 7.00e-51 193.00
IUUC-Mmu-063937 Mus musculus 50.00 8.00e-55 205.00
IUUC-Mac-065456 Musa acuminata 45.45 4.00e-51 193.00
IUUC-Mpu-065901 Mustela putorius furo 50.00 7.00e-55 205.00
IUUC-Mlu-067994 Myotis lucifugus 50.00 6.00e-55 205.00
IUUC-Nfi-068540 Neosartorya fischeri 45.34 2.00e-46 177.00
IUUC-Ncr-068760 Neurospora crassa 48.12 4.00e-55 206.00
IUUC-Nle-069463 Nomascus leucogenys 50.00 6.00e-55 206.00
IUUC-Opr-070298 Ochotona princeps 50.00 6.00e-55 205.00
IUUC-Ont-072615 Oreochromis niloticus 50.85 5.00e-57 213.00
IUUC-Ocu-074141 Oryctolagus cuniculus 50.00 6.00e-55 206.00
IUUC-Oba-075955 Oryza barthii 47.26 2.00e-47 181.00
IUUC-Obr-076545 Oryza brachyantha 47.26 2.00e-47 181.00
IUUC-Ogl-077252 Oryza glaberrima 46.41 6.00e-45 172.00
IUUC-Ogu-078986 Oryza glumaepatula 47.26 2.00e-47 181.00
IUUC-Oin-080166 Oryza indica 46.58 3.00e-45 174.00
IUUC-Olo-080390 Oryza longistaminata 46.12 7.00e-44 171.00
IUUC-Ome-082015 Oryza meridionalis 47.26 2.00e-47 181.00
IUUC-Oni-082397 Oryza nivara 47.26 2.00e-47 181.00
IUUC-Opu-083674 Oryza punctata 47.26 1.00e-47 181.00
IUUC-Oru-085199 Oryza rufipogon 47.26 2.00e-47 181.00
IUUC-Osa-085911 Oryza sativa 47.26 2.00e-47 181.00
IUUC-Ola-086325 Oryzias latipes 48.54 3.00e-51 194.00
IUUC-Olu-087857 Ostreococcus lucimarinus 49.04 2.00e-42 163.00
IUUC-Oga-088882 Otolemur garnettii 49.34 3.00e-51 194.00
IUUC-Oar-089311 Ovis aries 50.00 7.00e-55 205.00
IUUC-Ptr-090931 Pan troglodytes 50.00 6.00e-55 205.00
IUUC-Pan-092286 Papio anubis 50.00 6.00e-55 206.00
IUUC-Psi-093908 Pelodiscus sinensis 49.78 2.00e-52 197.00
IUUC-Pma-094737 Petromyzon marinus 45.34 5.00e-40 156.00
IUUC-Pno-094807 Phaeosphaeria nodorum 49.37 1.00e-49 187.00
IUUC-Ppa-095749 Physcomitrella patens 46.69 2.00e-50 191.00
IUUC-Pfo-097212 Poecilia formosa 50.00 1.00e-56 211.00
IUUC-Pab-097708 Pongo abelii 49.78 1.00e-51 194.00
IUUC-Pop-099924 Populus trichocarpa 46.19 2.00e-52 197.00
IUUC-Pca-100722 Procavia capensis 48.23 2.00e-26 110.00
IUUC-Ppe-101377 Prunus persica 48.10 2.00e-49 187.00
IUUC-Pva-103185 Pteropus vampyrus 50.00 8.00e-55 205.00
IUUC-Pgr-103361 Puccinia graminis 43.80 8.00e-35 139.00
IUUC-Ptt-103848 Puccinia triticina 38.75 4.00e-16 76.30
IUUC-Pte-104114 Pyrenophora teres 47.84 2.00e-47 180.00
IUUC-Pyt-104662 Pyrenophora triticirepentis 48.74 3.00e-50 189.00
IUUC-Rno-104906 Rattus norvegicus 50.00 7.00e-55 205.00
IUUC-Sha-106574 Sarcophilus harrisii 49.16 2.00e-53 200.00
IUUC-Sja-107706 Schizosaccharomyces japonicus 47.14 2.00e-46 177.00
IUUC-Spo-108378 Schizosaccharomyces pombe 47.11 1.00e-52 197.00
IUUC-Ssl-108491 Sclerotinia sclerotiorum 36.73 3.00e-03 31.20
IUUC-Smo-109108 Selaginella moellendorffii 43.27 9.00e-49 185.00
IUUC-Sit-110284 Setaria italica 48.10 1.00e-47 181.00
IUUC-Sly-111246 Solanum lycopersicum 45.76 3.00e-54 203.00
IUUC-Stu-112695 Solanum tuberosum 45.76 3.00e-54 203.00
IUUC-Sar-113015 Sorex araneus 52.07 1.00e-44 171.00
IUUC-Sbi-114495 Sorghum bicolor 48.10 9.00e-48 182.00
IUUC-Sre-114891 Sporisorium reilianum 56.36 3.00e-62 230.00
IUUC-Ssc-116142 Sus scrofa 50.00 6.00e-55 205.00
IUUC-Tgu-116946 Taeniopygia guttata 50.28 5.00e-39 152.00
IUUC-Tru-118224 Takifugu rubripes 49.15 9.00e-54 201.00
IUUC-Tsy-119004 Tarsius syrichta 48.86 4.00e-37 146.00
IUUC-Tni-120074 Tetraodon nigroviridis 51.27 4.00e-57 213.00
IUUC-Tca-121356 Theobroma cacao 48.52 4.00e-54 202.00
IUUC-Tre-122168 Trichoderma reesei 49.17 7.00e-58 215.00
IUUC-Tvi-122655 Trichoderma virens 47.92 1.00e-52 197.00
IUUC-Tae-124568 Triticum aestivum 47.26 3.00e-50 190.00
IUUC-Tur-126420 Triticum urartu 47.26 3.00e-50 190.00
IUUC-Tme-126937 Tuber melanosporum 54.01 3.00e-61 226.00
IUUC-Tbe-128080 Tupaia belangeri 48.31 6.00e-52 195.00
IUUC-Ttr-128811 Tursiops truncatus 50.00 6.00e-55 206.00
IUUC-Uma-129436 Ustilago maydis 55.08 3.00e-61 226.00
IUUC-Vda-129920 Verticillium dahliae 49.80 3.00e-49 186.00
IUUC-Vpa-130762 Vicugna pacos 50.00 3.00e-27 114.00
IUUC-Vvi-130840 Vitis vinifera 46.84 2.00e-52 197.00
IUUC-Xtr-131967 Xenopus tropicalis 51.77 2.00e-29 120.00
IUUC-Xma-134224 Xiphophorus maculatus 50.42 1.00e-56 211.00
IUUC-Yli-134643 Yarrowia lipolytica 52.54 3.00e-60 223.00
IUUC-Zma-135632 Zea mays 48.10 2.00e-49 187.00
Created Date 25-Jun-2017

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