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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-007043
UUCD1 version UUC-ArT-01176
Ensembl Protein ID AT3G04460.1
UniProt Accession Q9M841; Q8GYG2; PEX12_ARATH
Genbank Protein ID AAF63777.1; AEE74085.1; BAC42305.1
Protein Name Peroxisome biogenesis protein 12; Peroxin-12; Pex12p; Protein ABERRANT PEROXISOME MORPHOLOGY 4
Genbank Nucleotide ID AC022287; CP002686; BX824646
Gene Name PEX12; APM4; At3g04460; T27C4.11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G04460 AT3G04460.1 AT3G04460.1
AT3G04460 AT3G04460.2 AT3G04460.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndexPINAHINTMentha
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 24.87 1.00e-25 114.00 IUUC-Cel-018483
E3 activity/RING/RING 29.38 3.00e-32 137.00 IUUC-Hsa-046481
E3 activity/RING/RING 29.53 7.00e-31 132.00 IUUC-Mmu-063239
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5.
 Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin-protein ligase involved in monoubiquitination of PEX5.
Protein Sequence
(Fasta)
MLFQVGGEGT RPTFFEMAAA QQLPASLRAA LTYSLGVFAL RRSFLHKILD YEDEFFAALM 60
LILEGHSLRT TDGSFAESLY GLRRKSARLR LRKDSARKDS SEEVQHSGLE KRQRILSVVF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007043|E3,RING|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
TAAAGAACAT CCTTATTTAT GACGTAATTA ATAATGATCT CTCGAAATGC GTCTTTTCTT 60
CGTCTGTTCT ATCTTCTTTA CCAATTTCTG CAATTCTGGA GAAGCTAAAG GTCTCAATCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007043|E3,RING|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0576--Peroxisome
KW-0962--Peroxisome biogenesis
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR017375--PEX12
IPR006845--Pex_N
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF04757--Pex2_Pex12
Gene Ontology

GO:0005779--C:integral component of peroxisomal membrane
GO:1990429--C:peroxisomal importomer complex
GO:0005778--C:peroxisomal membrane
GO:0005777--C:peroxisome
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048598--P:embryonic morphogenesis
GO:0006635--P:fatty acid beta-oxidation
GO:0007031--P:peroxisome organization
GO:0016558--P:protein import into peroxisome matrix
GO:0006513--P:protein monoubiquitination
KEGG ath:AT3G04460
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001074 Aegilops tauschii 79.55 1.00e-58 219.00
IUUC-Aml-001787 Ailuropoda melanoleuca 29.17 8.00e-26 110.00
IUUC-Atr-002774 Amborella trichopoda 68.53 3.00e-157 547.00
IUUC-Apl-003884 Anas platyrhynchos 29.01 1.00e-14 73.20
IUUC-Aly-005467 Arabidopsis lyrata 98.47 0.00e+00 751.00
IUUC-Ago-007833 Ashbya gossypii 38.10 2.00e-05 42.70
IUUC-Acl-008074 Aspergillus clavatus 25.30 6.00e-19 88.20
IUUC-Afl-008656 Aspergillus flavus 27.97 1.00e-13 70.50
IUUC-Afu-008808 Aspergillus fumigatus 25.71 1.00e-18 87.00
IUUC-Ani-009154 Aspergillus nidulans 24.07 2.00e-16 80.10
IUUC-Ang-009803 Aspergillus niger 27.97 1.00e-13 70.10
IUUC-Aor-009984 Aspergillus oryzae 27.97 1.00e-13 70.10
IUUC-Ame-010950 Astyanax mexicanus 26.61 6.00e-19 87.80
IUUC-Bgr-011992 Blumeria graminis 21.12 1.00e-10 60.10
IUUC-Bta-012658 Bos taurus 28.61 2.00e-27 115.00
IUUC-Bdi-014625 Brachypodium distachyon 70.05 2.00e-158 551.00
IUUC-Bol-015713 Brassica oleracea 84.22 0.00e+00 645.00
IUUC-Bra-017037 Brassica rapa 83.82 8.00e-170 588.00
IUUC-Cel-018483 Caenorhabditis elegans 25.13 7.00e-28 117.00
IUUC-Cja-019601 Callithrix jacchus 29.56 1.00e-29 122.00
IUUC-Cfa-020854 Canis familiaris 28.46 6.00e-27 114.00
IUUC-Cpo-021920 Cavia porcellus 28.53 7.00e-30 124.00
IUUC-Cre-022816 Chlamydomonas reinhardtii 30.40 2.00e-36 146.00
IUUC-Csa-023545 Chlorocebus sabaeus 28.87 6.00e-25 107.00
IUUC-Cin-025523 Ciona intestinalis 24.55 9.00e-23 100.00
IUUC-Csv-026141 Ciona savignyi 23.48 3.00e-22 98.60
IUUC-Cgl-026641 Colletotrichum gloeosporioides 32.31 4.00e-11 61.60
IUUC-Cne-026949 Cryptococcus neoformans 36.96 1.00e-03 37.00
IUUC-Cme-027334 Cyanidioschyzon merolae 27.75 7.00e-22 97.10
IUUC-Dre-027602 Danio rerio 25.07 7.00e-27 114.00
IUUC-Dno-029980 Dasypus novemcinctus 29.46 9.00e-29 120.00
IUUC-Dor-030627 Dipodomys ordii 29.90 2.00e-29 122.00
IUUC-Dse-031219 Dothistroma septosporum 22.22 7.00e-15 74.30
IUUC-Dme-031953 Drosophila melanogaster 31.00 2.00e-12 65.90
IUUC-Ete-032811 Echinops telfairi 28.21 4.00e-30 124.00
IUUC-Eca-033635 Equus caballus 29.64 1.00e-30 126.00
IUUC-Eeu-034584 Erinaceus europaeus 28.79 2.00e-32 132.00
IUUC-Fca-035710 Felis catus 29.64 6.00e-30 124.00
IUUC-Fal-037416 Ficedula albicollis 26.74 3.00e-20 91.70
IUUC-Fox-037908 Fusarium oxysporum 24.56 6.00e-22 97.80
IUUC-Fso-038283 Fusarium solani 25.06 2.00e-22 99.00
IUUC-Gmo-039567 Gadus morhua 32.56 2.00e-06 45.80
IUUC-Ggr-040097 Gaeumannomyces graminis 33.86 2.00e-08 52.80
IUUC-Gga-040757 Gallus gallus 25.92 8.00e-28 117.00
IUUC-Gac-042008 Gasterosteus aculeatus 36.84 7.00e-11 60.80
IUUC-Gma-044278 Glycine max 71.17 2.00e-164 570.00
IUUC-Ggo-044888 Gorilla gorilla 29.64 2.00e-31 129.00
IUUC-Hsa-046481 Homo sapiens 29.64 3.00e-31 128.00
IUUC-Hvu-047274 Hordeum vulgare 79.55 3.00e-58 216.00
IUUC-Itr-048925 Ictidomys tridecemlineatus 28.76 2.00e-27 115.00
IUUC-Kpa-049394 Komagataella pastoris 26.61 6.00e-08 51.20
IUUC-Lch-050347 Latimeria chalumnae 27.44 2.00e-30 125.00
IUUC-Lpe-051711 Leersia perrieri 69.29 4.00e-153 533.00
IUUC-Loc-052943 Lepisosteus oculatus 34.58 2.00e-12 65.90
IUUC-Lma-053231 Leptosphaeria maculans 25.07 3.00e-18 87.00
IUUC-Laf-053506 Loxodonta africana 29.08 3.00e-28 118.00
IUUC-Mcc-055863 Macaca mulatta 28.61 1.00e-24 107.00
IUUC-Meu-056343 Macropus eugenii 27.81 2.00e-23 102.00
IUUC-Mor-057266 Magnaporthe oryzae 25.84 3.00e-11 62.40
IUUC-Mtr-058337 Medicago truncatula 66.33 3.00e-132 463.00
IUUC-Mla-058905 Melampsora laricipopulina 28.97 1.00e-34 140.00
IUUC-Mga-059695 Meleagris gallopavo 24.78 1.00e-22 100.00
IUUC-Mvi-060538 Microbotryum violaceum 28.08 8.00e-29 120.00
IUUC-Mmr-061680 Microcebus murinus 29.38 4.00e-30 124.00
IUUC-Mdo-063013 Monodelphis domestica 27.30 2.00e-22 99.40
IUUC-Mmu-063239 Mus musculus 29.53 3.00e-34 138.00
IUUC-Mac-064765 Musa acuminata 72.01 3.00e-159 553.00
IUUC-Mpu-066866 Mustela putorius furo 29.50 2.00e-25 108.00
IUUC-Mlu-067535 Myotis lucifugus 29.59 3.00e-30 125.00
IUUC-Nfi-068561 Neosartorya fischeri 25.30 1.00e-18 87.00
IUUC-Ncr-068700 Neurospora crassa 22.39 3.00e-10 59.30
IUUC-Nle-069709 Nomascus leucogenys 29.38 1.00e-28 119.00
IUUC-Opr-070983 Ochotona princeps 25.84 6.00e-25 107.00
IUUC-Ont-071734 Oreochromis niloticus 27.75 3.00e-16 78.60
IUUC-Ocu-074733 Oryctolagus cuniculus 29.38 2.00e-31 129.00
IUUC-Oba-075943 Oryza barthii 69.80 2.00e-157 548.00
IUUC-Obr-076017 Oryza brachyantha 69.47 2.00e-149 521.00
IUUC-Ogl-077702 Oryza glaberrima 69.80 2.00e-157 548.00
IUUC-Ogu-078692 Oryza glumaepatula 69.70 2.00e-156 544.00
IUUC-Oin-079133 Oryza indica 69.80 3.00e-157 547.00
IUUC-Oni-082667 Oryza nivara 69.80 3.00e-157 547.00
IUUC-Opu-083858 Oryza punctata 69.21 1.00e-146 512.00
IUUC-Oru-084886 Oryza rufipogon 69.47 2.00e-157 547.00
IUUC-Osa-085512 Oryza sativa 69.80 2.00e-157 548.00
IUUC-Ola-087150 Oryzias latipes 23.81 4.00e-18 84.70
IUUC-Olu-087595 Ostreococcus lucimarinus 35.10 1.00e-44 173.00
IUUC-Oga-088647 Otolemur garnettii 28.83 3.00e-30 125.00
IUUC-Oar-089308 Ovis aries 28.87 4.00e-27 114.00
IUUC-Ptr-090543 Pan troglodytes 29.90 5.00e-32 130.00
IUUC-Pan-091907 Papio anubis 29.12 4.00e-25 107.00
IUUC-Psi-093888 Pelodiscus sinensis 28.17 3.00e-29 121.00
IUUC-Pno-094821 Phaeosphaeria nodorum 25.18 4.00e-10 58.90
IUUC-Ppa-095287 Physcomitrella patens 53.92 4.00e-112 397.00
IUUC-Pfo-097238 Poecilia formosa 26.94 1.00e-24 106.00
IUUC-Pab-097938 Pongo abelii 29.64 2.00e-31 129.00
IUUC-Pop-098899 Populus trichocarpa 76.02 2.00e-180 624.00
IUUC-Pca-100488 Procavia capensis 28.02 8.00e-11 60.50
IUUC-Ppe-101914 Prunus persica 75.76 9.00e-179 618.00
IUUC-Pva-102469 Pteropus vampyrus 28.09 6.00e-15 74.30
IUUC-Pgr-103388 Puccinia graminis 28.16 7.00e-32 130.00
IUUC-Ptt-103988 Puccinia triticina 28.26 8.00e-31 127.00
IUUC-Pte-104186 Pyrenophora teres 24.87 6.00e-14 71.60
IUUC-Pyt-104605 Pyrenophora triticirepentis 25.59 3.00e-14 72.40
IUUC-Rno-105071 Rattus norvegicus 29.79 1.00e-34 139.00
IUUC-Sce-106238 Saccharomyces cerevisiae 23.47 5.00e-10 58.20
IUUC-Sha-107200 Sarcophilus harrisii 27.83 5.00e-20 90.90
IUUC-Sja-108008 Schizosaccharomyces japonicus 29.06 1.00e-07 50.10
IUUC-Spo-108077 Schizosaccharomyces pombe 25.00 6.00e-07 47.80
IUUC-Smo-109083 Selaginella moellendorffii 56.63 2.00e-121 427.00
IUUC-Sit-110306 Setaria italica 71.32 6.00e-147 513.00
IUUC-Sly-111409 Solanum lycopersicum 76.08 7.00e-166 575.00
IUUC-Stu-112852 Solanum tuberosum 76.59 4.00e-167 580.00
IUUC-Sar-112967 Sorex araneus 28.72 2.00e-10 58.20
IUUC-Sbi-114722 Sorghum bicolor 71.50 1.00e-140 492.00
IUUC-Sre-115089 Sporisorium reilianum 26.34 7.00e-31 127.00
IUUC-Ssc-115367 Sus scrofa 28.87 5.00e-32 130.00
IUUC-Tgu-117176 Taeniopygia guttata 27.23 4.00e-23 101.00
IUUC-Tru-118162 Takifugu rubripes 24.75 5.00e-20 90.90
IUUC-Tsy-119231 Tarsius syrichta 29.90 3.00e-31 128.00
IUUC-Tni-119962 Tetraodon nigroviridis 25.19 9.00e-20 90.50
IUUC-Tca-121100 Theobroma cacao 77.10 2.00e-170 590.00
IUUC-Tre-122015 Trichoderma reesei 24.14 7.00e-20 90.90
IUUC-Tvi-122573 Trichoderma virens 25.25 2.00e-20 93.20
IUUC-Tae-123664 Triticum aestivum 70.13 6.00e-148 516.00
IUUC-Tur-126843 Triticum urartu 70.05 3.00e-148 517.00
IUUC-Tme-127060 Tuber melanosporum 23.96 7.00e-23 100.00
IUUC-Ttr-128998 Tursiops truncatus 28.39 7.00e-32 130.00
IUUC-Uma-129524 Ustilago maydis 28.99 5.00e-27 114.00
IUUC-Vvi-130933 Vitis vinifera 74.05 2.00e-167 580.00
IUUC-Xtr-132968 Xenopus tropicalis 26.72 2.00e-22 99.40
IUUC-Xma-133355 Xiphophorus maculatus 25.19 5.00e-24 104.00
IUUC-Yli-134388 Yarrowia lipolytica 26.32 2.00e-26 112.00
IUUC-Zma-135423 Zea mays 71.07 8.00e-145 505.00
Created Date 25-Jun-2017

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