iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045100

Ensembl Protein ID

ENSGGOP00000012291.2

UniProt Accession

G3RA35; G3RA35_GORGO

Protein Name

Uncharacterized protein

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000012580.2	ENSGGOT00000012647.2	ENSGGOP00000012291.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.10e-67	222.5	1165	1216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1165 QVIGMYDYTAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVK 1216
           46779**********************..8889******..9*************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
ICRFQDYFQE LRLTQEEMTI INKLSKAQLS IYLSPTVRFP TMPEDAGAIR KKPGLKIKTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTCCAACACC TTTTGGTGGT AAGTTTTCAG AAATTTCTCT TTTTAATGTA 60
CTTTGGGACC AGATTTTAAA AACTTGATAT TATGGCAAAT TTAAAATTAA AAGGTAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF12763--EF-hand_4
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00027--EH
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	40.48	3.00e-13	71.60
IUUC-Aly-005557	Arabidopsis lyrata	37.04	3.00e-11	64.70
IUUC-Ago-007935	Ashbya gossypii	34.33	2.00e-14	73.90
IUUC-Acl-008295	Aspergillus clavatus	31.61	5.00e-16	79.70
IUUC-Ani-009403	Aspergillus nidulans	41.38	2.00e-15	73.90
IUUC-Aor-010021	Aspergillus oryzae	30.00	5.00e-19	89.70
IUUC-Ate-010587	Aspergillus terreus	32.90	1.00e-17	85.10
IUUC-Bdi-014016	Brachypodium distachyon	38.89	3.00e-13	71.20
IUUC-Cpo-021352	Cavia porcellus	80.84	0.00e+00	1744.00
IUUC-Cne-027017	Cryptococcus neoformans	33.33	1.00e-16	81.60
IUUC-Ete-032927	Echinops telfairi	86.28	0.00e+00	971.00
IUUC-Eeu-034977	Erinaceus europaeus	92.28	0.00e+00	1140.00
IUUC-Hsa-045699	Homo sapiens	98.95	0.00e+00	1457.00
IUUC-Hvu-047530	Hordeum vulgare	32.54	6.00e-14	72.80
IUUC-Itr-048773	Ictidomys tridecemlineatus	97.24	0.00e+00	1461.00
IUUC-Kpa-049215	Komagataella pastoris	39.85	4.00e-15	76.30
IUUC-Lpe-051250	Leersia perrieri	40.48	1.00e-13	72.00
IUUC-Mga-059432	Meleagris gallopavo	79.21	0.00e+00	850.00
IUUC-Mpu-066402	Mustela putorius furo	91.77	0.00e+00	912.00
IUUC-Mlu-067025	Myotis lucifugus	81.63	0.00e+00	1171.00
IUUC-Nle-069448	Nomascus leucogenys	88.69	0.00e+00	1258.00
IUUC-Ocu-073753	Oryctolagus cuniculus	87.63	0.00e+00	1908.00
IUUC-Ogu-078849	Oryza glumaepatula	40.48	2.00e-13	72.00
IUUC-Olo-080259	Oryza longistaminata	40.48	2.00e-13	72.00
IUUC-Ome-081199	Oryza meridionalis	40.48	1.00e-13	72.40
IUUC-Oni-082167	Oryza nivara	40.48	3.00e-13	71.20
IUUC-Oru-084541	Oryza rufipogon	40.48	3.00e-13	71.20
IUUC-Ptr-091363	Pan troglodytes	99.08	0.00e+00	1459.00
IUUC-Pan-092385	Papio anubis	98.56	0.00e+00	1429.00
IUUC-Psi-093551	Pelodiscus sinensis	88.20	0.00e+00	1266.00
IUUC-Ppa-095426	Physcomitrella patens	39.74	6.00e-12	66.60
IUUC-Pab-098281	Pongo abelii	94.21	0.00e+00	1248.00
IUUC-Pop-098963	Populus trichocarpa	39.02	2.00e-10	62.40
IUUC-Pca-100270	Procavia capensis	78.20	0.00e+00	956.00
IUUC-Pva-102335	Pteropus vampyrus	95.54	0.00e+00	1414.00
IUUC-Pgr-103652	Puccinia graminis	32.45	1.00e-10	62.00
IUUC-Sce-106410	Saccharomyces cerevisiae	30.43	5.00e-13	69.30
IUUC-Sja-107863	Schizosaccharomyces japonicus	31.85	7.00e-15	75.90
IUUC-Spo-108101	Schizosaccharomyces pombe	42.57	3.00e-16	80.90
IUUC-Smo-108995	Selaginella moellendorffii	36.62	5.00e-08	52.80
IUUC-Sit-110414	Setaria italica	39.29	2.00e-13	71.60
IUUC-Sbi-114170	Sorghum bicolor	37.78	2.00e-13	72.00
IUUC-Ssc-116237	Sus scrofa	92.71	0.00e+00	1263.00
IUUC-Tae-123242	Triticum aestivum	40.48	2.00e-13	71.60
IUUC-Tur-126623	Triticum urartu	38.89	2.00e-13	71.20
IUUC-Tbe-127754	Tupaia belangeri	82.96	0.00e+00	1668.00
IUUC-Vpa-130687	Vicugna pacos	91.83	0.00e+00	1193.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence