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Tag Content
UUCD2 ID IUUC-Gga-040827
UUCD1 version UUC-GaG-00783
Ensembl Protein ID ENSGALP00000003853.3
UniProt Accession Q5ZMV9; WDR24_CHICK
Genbank Protein ID CAG30934.1
Protein Name WD repeat-containing protein 24
Genbank Nucleotide ID AJ719275
Gene Name WDR24; RCJMB04_1a19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000002450.4 ENSGALT00000003862.4 ENSGALP00000003853.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.30e-27 93.8 122 155
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           H+++v+c+++   d + l++G++D+ +kvWD+ t
   Q: 122  HNGPVFCCDWhpEDrGWLATGGRDKMVKVWDMNT 155
           ***********655899**************866 PP
   
Organism Gallus gallus
Functional Description
(View)

Functional Description


     Required for the regulation of the TORC1 pathway by amino acids. Also promotes the acidification of lysosomes and facilitates autophagic flux.
 Required for the regulation of the TORC1 pathway by amino acids. Also promotes the acidification of lysosomes and facilitates autophagic flux.
Protein Sequence
(Fasta)
MDENLLATAA TNGVVVTWNL GKPSRNKQDQ LFTEHKRTVN KVCFHPTEVY MLLSGSQDGY 60
MKCFDLRKKD SVSTFSGQSE SVRDVQFSIR DYFTFAATFE NGNVQLWDIR RPDRYERMFT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040827|E3,WD_repeat|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGAAGGGG GCGGGGCGTA CGCCGGCGAG GCCGGCGGGG CCTGTGGGGC CGGTGCTGCC 60
GGCGGAGCTG CGGTATGGGG GGCGATGGGA GGCTCCGAGG GGGGAACCCG TGGTCCGTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040827|E3,WD_repeat|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0006914--P:autophagy
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling
GO:0010506--P:regulation of autophagy
KEGG gga:416406
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001294 Ailuropoda melanoleuca 81.75 0.00e+00 1208.00
IUUC-Apl-004177 Anas platyrhynchos 97.76 0.00e+00 1446.00
IUUC-Ago-007803 Ashbya gossypii 26.84 4.00e-21 97.40
IUUC-Acl-008356 Aspergillus clavatus 29.83 2.00e-33 138.00
IUUC-Afu-009013 Aspergillus fumigatus 32.50 2.00e-32 134.00
IUUC-Ani-009185 Aspergillus nidulans 29.83 1.00e-32 135.00
IUUC-Ang-009533 Aspergillus niger 30.85 5.00e-34 140.00
IUUC-Aor-010148 Aspergillus oryzae 30.82 4.00e-34 140.00
IUUC-Ate-010528 Aspergillus terreus 29.93 4.00e-32 133.00
IUUC-Ame-011386 Astyanax mexicanus 74.26 0.00e+00 1040.00
IUUC-Bgr-012040 Blumeria graminis 27.11 1.00e-17 85.90
IUUC-Bta-013092 Bos taurus 81.90 0.00e+00 1246.00
IUUC-Bci-013751 Botrytis cinerea 29.97 4.00e-30 127.00
IUUC-Cel-018274 Caenorhabditis elegans 31.28 1.00e-42 170.00
IUUC-Cja-019083 Callithrix jacchus 75.88 0.00e+00 710.00
IUUC-Cfa-020652 Canis familiaris 80.70 0.00e+00 1023.00
IUUC-Cpo-021847 Cavia porcellus 82.18 0.00e+00 1214.00
IUUC-Csa-023407 Chlorocebus sabaeus 81.47 0.00e+00 1207.00
IUUC-Cin-025129 Ciona intestinalis 37.80 5.00e-112 398.00
IUUC-Csv-025991 Ciona savignyi 35.30 2.00e-105 377.00
IUUC-Cgl-026445 Colletotrichum gloeosporioides 26.60 2.00e-20 94.70
IUUC-Dre-028566 Danio rerio 73.49 0.00e+00 1030.00
IUUC-Dno-029775 Dasypus novemcinctus 78.22 5.00e-169 587.00
IUUC-Dor-030655 Dipodomys ordii 66.38 7.00e-115 407.00
IUUC-Dse-031422 Dothistroma septosporum 29.31 3.00e-31 130.00
IUUC-Dme-032155 Drosophila melanogaster 38.09 7.00e-134 471.00
IUUC-Ete-032984 Echinops telfairi 76.24 0.00e+00 1098.00
IUUC-Eca-034065 Equus caballus 82.04 0.00e+00 1199.00
IUUC-Eeu-034460 Erinaceus europaeus 72.86 0.00e+00 1044.00
IUUC-Fca-035432 Felis catus 81.33 0.00e+00 1187.00
IUUC-Fal-037575 Ficedula albicollis 99.01 0.00e+00 1477.00
IUUC-Fox-037810 Fusarium oxysporum 25.35 5.00e-21 97.10
IUUC-Fso-038116 Fusarium solani 24.39 8.00e-19 89.70
IUUC-Gmo-038937 Gadus morhua 75.63 0.00e+00 1087.00
IUUC-Ggr-039930 Gaeumannomyces graminis 25.26 3.00e-18 87.80
IUUC-Gac-042168 Gasterosteus aculeatus 78.98 0.00e+00 1131.00
IUUC-Ggo-044772 Gorilla gorilla 80.06 0.00e+00 1059.00
IUUC-Hsa-046676 Homo sapiens 80.22 0.00e+00 1061.00
IUUC-Itr-048506 Ictidomys tridecemlineatus 82.29 0.00e+00 1200.00
IUUC-Kpa-049109 Komagataella pastoris 34.26 6.00e-38 152.00
IUUC-Lch-050410 Latimeria chalumnae 82.68 0.00e+00 1230.00
IUUC-Loc-051786 Lepisosteus oculatus 80.20 0.00e+00 1174.00
IUUC-Lma-053068 Leptosphaeria maculans 31.27 4.00e-32 134.00
IUUC-Laf-054171 Loxodonta africana 80.20 0.00e+00 1190.00
IUUC-Mcc-055764 Macaca mulatta 76.27 0.00e+00 989.00
IUUC-Meu-055941 Macropus eugenii 86.34 0.00e+00 637.00
IUUC-Mor-056918 Magnaporthe oryzae 26.89 9.00e-15 76.30
IUUC-Mla-058924 Melampsora laricipopulina 22.86 3.00e-20 92.80
IUUC-Mga-059495 Meleagris gallopavo 100.00 0.00e+00 1485.00
IUUC-Mvi-060314 Microbotryum violaceum 26.14 5.00e-21 97.40
IUUC-Mmr-061375 Microcebus murinus 81.01 0.00e+00 1168.00
IUUC-Mdo-062605 Monodelphis domestica 89.65 0.00e+00 1349.00
IUUC-Mmu-064313 Mus musculus 81.75 0.00e+00 1222.00
IUUC-Mpu-066860 Mustela putorius furo 82.18 0.00e+00 1211.00
IUUC-Mlu-067268 Myotis lucifugus 79.71 0.00e+00 1091.00
IUUC-Nfi-068523 Neosartorya fischeri 32.50 9.00e-33 135.00
IUUC-Ncr-068694 Neurospora crassa 26.26 2.00e-21 98.60
IUUC-Opr-070270 Ochotona princeps 77.19 0.00e+00 993.00
IUUC-Ont-071681 Oreochromis niloticus 77.82 0.00e+00 1123.00
IUUC-Ola-086651 Oryzias latipes 70.08 0.00e+00 1110.00
IUUC-Oga-088730 Otolemur garnettii 74.71 0.00e+00 1168.00
IUUC-Oar-090328 Ovis aries 92.23 1.00e-109 388.00
IUUC-Ptr-091668 Pan troglodytes 81.87 6.00e-174 603.00
IUUC-Pan-092619 Papio anubis 81.47 0.00e+00 1206.00
IUUC-Psi-093906 Pelodiscus sinensis 95.46 0.00e+00 1429.00
IUUC-Pno-094980 Phaeosphaeria nodorum 31.11 2.00e-31 131.00
IUUC-Pfo-096284 Poecilia formosa 76.06 0.00e+00 1118.00
IUUC-Pab-097668 Pongo abelii 75.52 0.00e+00 1124.00
IUUC-Pca-100865 Procavia capensis 78.34 0.00e+00 1154.00
IUUC-Pva-102869 Pteropus vampyrus 72.49 0.00e+00 1146.00
IUUC-Pte-104040 Pyrenophora teres 30.28 5.00e-31 130.00
IUUC-Pyt-104648 Pyrenophora triticirepentis 29.05 2.00e-18 88.20
IUUC-Rno-105555 Rattus norvegicus 82.32 0.00e+00 1196.00
IUUC-Sce-106263 Saccharomyces cerevisiae 28.57 1.00e-13 72.40
IUUC-Sha-106936 Sarcophilus harrisii 87.96 0.00e+00 1192.00
IUUC-Sja-107793 Schizosaccharomyces japonicus 24.50 3.00e-40 160.00
IUUC-Spo-108236 Schizosaccharomyces pombe 27.88 4.00e-36 146.00
IUUC-Ssl-108603 Sclerotinia sclerotiorum 31.14 2.00e-30 128.00
IUUC-Sar-113686 Sorex araneus 74.86 8.00e-160 557.00
IUUC-Ssc-116279 Sus scrofa 79.59 0.00e+00 1092.00
IUUC-Tgu-116557 Taeniopygia guttata 80.07 0.00e+00 941.00
IUUC-Tru-118545 Takifugu rubripes 75.79 0.00e+00 1133.00
IUUC-Tni-120098 Tetraodon nigroviridis 77.97 0.00e+00 1149.00
IUUC-Tre-121960 Trichoderma reesei 24.31 1.00e-16 82.40
IUUC-Tvi-122484 Trichoderma virens 24.85 2.00e-16 81.60
IUUC-Tme-127028 Tuber melanosporum 32.83 1.00e-59 224.00
IUUC-Ttr-128346 Tursiops truncatus 72.57 0.00e+00 1130.00
IUUC-Vda-129729 Verticillium dahliae 24.59 3.00e-23 104.00
IUUC-Xtr-131862 Xenopus tropicalis 84.90 0.00e+00 1079.00
IUUC-Xma-133385 Xiphophorus maculatus 75.92 0.00e+00 1116.00
IUUC-Yli-134444 Yarrowia lipolytica 24.69 1.00e-29 125.00
Created Date 25-Jun-2017

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