iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062200

UUCD1 version

UUC-MoD-00029

Ensembl Protein ID

ENSMODP00000027365.1

UniProt Accession

H9H985; H9H985_MONDO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000022806.1	ENSMODT00000028906.1	ENSMODP00000027365.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-53	174.6	349	387
UBD/Beta-Prp	6.40e-66	222.7	313	515

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W++++  +++
   Q: 349  GHTNKVNAIKWdPTgNLLASCSDDMTLKIWSMKQESCVH 387
           8***********778*****************9999986 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
             +v++ ++++ +a+ s+d +i v ++ +   +++++gh+++v+a+k++p+g++l+++s+D+t+k+w++++ +cvh l++h++++++++
   Q: 313  ALDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNKVNAIKWDPTGNLLASCSDDMTLKIWSMKQESCVHDLQAHNKEIYTIK 400
           445556.7788888888888888888888888888888888888888888888888888888888888888888888888888888888 PP
   S: 102  fsp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           +sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g l++  +g  t+
   Q: 401  WSPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQMGALVHSYRG--TG 486
           88866665544222468888888888888888888888.8888888888888888888888888888888888888888888887..88 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq 210
            +  + ++  g  + + + dg+v + dl+
   Q: 487  GIFEVCWNAAGDKVGASASDGSVCVLDLR 515
           88888888888888888888888887775 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

KMSISSDEVN FLVYRYLQES GFSHSAFTFG IESHISQSNI NGALVPPAAL ISIIQKGLQY 60
VEAEVSINED GTLFDGRPIE SLSLIDAVMP DVVQTRQQAY RDKLAQQQAA AAAATAAATT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGAGTA TAAGCAGTGA TGAGGTCAAC TTCTTGGTAT ATAGATACTT GCAAGAGTCA 60
GGGTTTTCTC ATTCAGCATT TACCTTTGGT ATAGAAAGCC ATATCAGCCA GTCTAATATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007869	Ashbya gossypii	27.98	1.00e-32	134.00
IUUC-Cho-024872	Choloepus hoffmanni	97.02	7.00e-111	394.00
IUUC-Kpa-049338	Komagataella pastoris	28.52	2.00e-31	130.00
IUUC-Sce-106132	Saccharomyces cerevisiae	24.87	7.00e-42	165.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence