iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116898

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01012552

Gene Name

TBL1X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008500.1	ENSTGUT00000008880.1	ENSTGUP00000008787.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-54	177.5	450	488
UBD/Beta-Prp	1.90e-64	217.5	351	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g+l++s
   Q: 450  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGTLVHS 488
           9**********999*******************999876 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.........sgdklvsGshdrtirvwdle 124
           +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp         s+  l+s+s d+t+r+wd++
   Q: 351  VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpgtsnpnSNIMLASASFDSTVRLWDVD 439
           57889999999999999999999999999999999999999999999999999999999977777666444689999999999999999 PP
   S: 125  tgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
            g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + ++  g  + + + dg+v + dl+
   Q: 440  RGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRG--TGGIFEVCWNARGDKVGASASDGSVCVLDLR 522
           999999.9999999999999999999999999999999999999999999998..9999999999999999999999999888876 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQASA AAAAAATAAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCATAA CCAGTGACGA AGTGAATTTC TTGGTGTATC GCTATCTCCA GGAATCGGGT 60
AAATTTTTTG TCTTTCTTCA TAACTTCTGG TCATAAATGA AATAGGGAAA TTGCCTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

KEGG

tgu:100221758

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	59.29	2.00e-54	203.00
IUUC-Aml-001450	Ailuropoda melanoleuca	92.93	0.00e+00	994.00
IUUC-Atr-002514	Amborella trichopoda	64.29	4.00e-143	501.00
IUUC-Apl-003232	Anas platyrhynchos	99.81	0.00e+00	1018.00
IUUC-Aca-005035	Anolis carolinensis	95.83	0.00e+00	1010.00
IUUC-Aly-005622	Arabidopsis lyrata	55.58	2.00e-119	422.00
IUUC-Ath-007137	Arabidopsis thaliana	58.95	1.00e-120	426.00
IUUC-Ago-007869	Ashbya gossypii	27.68	9.00e-33	134.00
IUUC-Bta-013202	Bos taurus	96.02	0.00e+00	1006.00
IUUC-Bdi-014315	Brachypodium distachyon	60.92	2.00e-134	472.00
IUUC-Bol-016277	Brassica oleracea	56.70	9.00e-126	443.00
IUUC-Bra-016944	Brassica rapa	57.59	1.00e-125	443.00
IUUC-Cja-019281	Callithrix jacchus	92.16	0.00e+00	978.00
IUUC-Cfa-020929	Canis familiaris	95.63	0.00e+00	1001.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.16	9.00e-132	463.00
IUUC-Csa-023943	Chlorocebus sabaeus	93.88	0.00e+00	975.00
IUUC-Cin-025704	Ciona intestinalis	72.68	0.00e+00	796.00
IUUC-Csv-026257	Ciona savignyi	70.64	0.00e+00	765.00
IUUC-Cne-026946	Cryptococcus neoformans	38.91	8.00e-31	128.00
IUUC-Cme-027258	Cyanidioschyzon merolae	39.55	1.00e-104	372.00
IUUC-Dno-028926	Dasypus novemcinctus	94.12	0.00e+00	986.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	4.00e-176	611.00
IUUC-Ete-032822	Echinops telfairi	84.70	0.00e+00	845.00
IUUC-Eca-033897	Equus caballus	96.58	0.00e+00	1005.00
IUUC-Fca-036462	Felis catus	96.20	0.00e+00	1002.00
IUUC-Fal-037388	Ficedula albicollis	99.81	0.00e+00	1029.00
IUUC-Gga-040671	Gallus gallus	99.81	0.00e+00	1029.00
IUUC-Gac-041851	Gasterosteus aculeatus	90.63	0.00e+00	940.00
IUUC-Gma-044208	Glycine max	48.60	7.00e-153	533.00
IUUC-Ggo-045373	Gorilla gorilla	93.17	0.00e+00	984.00
IUUC-Hsa-045841	Homo sapiens	93.73	0.00e+00	984.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	98.66	0.00e+00	775.00
IUUC-Lch-050535	Latimeria chalumnae	92.54	0.00e+00	987.00
IUUC-Lpe-051084	Leersia perrieri	61.54	1.00e-133	469.00
IUUC-Laf-054071	Loxodonta africana	94.71	0.00e+00	1010.00
IUUC-Mcc-055233	Macaca mulatta	93.02	0.00e+00	959.00
IUUC-Mtr-058624	Medicago truncatula	59.89	9.00e-127	446.00
IUUC-Mga-059895	Meleagris gallopavo	98.47	0.00e+00	1025.00
IUUC-Mvi-060557	Microbotryum violaceum	37.04	2.00e-70	260.00
IUUC-Mmr-061286	Microcebus murinus	96.60	0.00e+00	1010.00
IUUC-Mmu-063447	Mus musculus	95.83	0.00e+00	1001.00
IUUC-Nle-069151	Nomascus leucogenys	93.89	0.00e+00	980.00
IUUC-Ont-072252	Oreochromis niloticus	90.25	0.00e+00	961.00
IUUC-Oan-073562	Ornithorhynchus anatinus	96.96	0.00e+00	1013.00
IUUC-Oba-075618	Oryza barthii	47.93	2.00e-141	495.00
IUUC-Obr-076718	Oryza brachyantha	61.13	7.00e-135	473.00
IUUC-Ogl-077302	Oryza glaberrima	50.54	8.00e-155	540.00
IUUC-Ogu-078718	Oryza glumaepatula	50.54	8.00e-155	540.00
IUUC-Olo-080427	Oryza longistaminata	61.89	3.00e-129	455.00
IUUC-Ome-081696	Oryza meridionalis	49.46	1.00e-149	522.00
IUUC-Oni-082137	Oryza nivara	50.54	8.00e-155	540.00
IUUC-Opu-083505	Oryza punctata	47.93	1.00e-142	499.00
IUUC-Oru-085276	Oryza rufipogon	50.54	4.00e-155	541.00
IUUC-Osa-085791	Oryza sativa	50.54	8.00e-155	540.00
IUUC-Olu-087589	Ostreococcus lucimarinus	51.74	5.00e-155	540.00
IUUC-Oar-089506	Ovis aries	94.65	0.00e+00	1003.00
IUUC-Ptr-090793	Pan troglodytes	91.98	0.00e+00	949.00
IUUC-Pan-091909	Papio anubis	93.35	0.00e+00	984.00
IUUC-Psi-093358	Pelodiscus sinensis	91.20	0.00e+00	963.00
IUUC-Ppa-095868	Physcomitrella patens	65.75	4.00e-139	488.00
IUUC-Pfo-097214	Poecilia formosa	89.29	0.00e+00	929.00
IUUC-Pab-098317	Pongo abelii	93.41	0.00e+00	963.00
IUUC-Pop-098989	Populus trichocarpa	57.39	3.00e-128	451.00
IUUC-Rno-105857	Rattus norvegicus	95.83	0.00e+00	1001.00
IUUC-Sha-107326	Sarcophilus harrisii	95.60	0.00e+00	1019.00
IUUC-Smo-109301	Selaginella moellendorffii	62.67	1.00e-140	492.00
IUUC-Sit-110710	Setaria italica	61.62	1.00e-139	489.00
IUUC-Sly-111042	Solanum lycopersicum	50.38	2.00e-150	525.00
IUUC-Sbi-114420	Sorghum bicolor	61.13	1.00e-139	489.00
IUUC-Ssc-115646	Sus scrofa	95.65	0.00e+00	1014.00
IUUC-Tru-117862	Takifugu rubripes	90.82	0.00e+00	952.00
IUUC-Tni-119656	Tetraodon nigroviridis	91.40	0.00e+00	951.00
IUUC-Tca-121739	Theobroma cacao	54.04	2.00e-124	439.00
IUUC-Tae-125368	Triticum aestivum	59.11	9.00e-135	473.00
IUUC-Ttr-128826	Tursiops truncatus	96.88	0.00e+00	924.00
IUUC-Uma-129469	Ustilago maydis	43.92	5.00e-59	222.00
IUUC-Vvi-131193	Vitis vinifera	55.50	4.00e-129	454.00
IUUC-Xma-133591	Xiphophorus maculatus	89.10	0.00e+00	929.00
IUUC-Yli-134648	Yarrowia lipolytica	26.65	6.00e-42	165.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence