iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090384

Ensembl Protein ID

ENSOARP00000006522.1

UniProt Accession

W5P7W8; W5P7W8_SHEEP

Genbank Protein ID

ENSOARP00000006522

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01028858

Gene Name

PLEKHG2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000006086.1	ENSOART00000006620.1	ENSOARP00000006522.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	30.22	6.00e-12	68.90	IUUC-Sce-106197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MPEGARGLGL SKPSPSLGHR GEVCDCAAVC DTRTAPATPA MTSPRGSGSS TSLSTVGSEG 60
DPAPGPTPAC SASRPEPLPG PPIRLHLSPV GTSGSSKPSR LERVAREIVE TEGAYVRDLR 120

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Nucleotide Sequence
(Fasta)

ATGCCCGAGG GAGCCCGTGG ACTGGGCCTG TCCAAACCCA GCCCTAGCCT CGGCCACAGA 60
GGTGAAGTGT GTGACTGTGC GGCTGTGTGT GACACTCGGA CAGGTGAGCG GGTGAGGGAG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001849--PH_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN

Pfam

PF00169--PH
PF00621--RhoGEF

SMART

SM00233--PH
SM00325--RhoGEF

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-008003	Ashbya gossypii	27.91	2.00e-14	74.30
IUUC-Acl-008142	Aspergillus clavatus	26.69	6.00e-16	79.70
IUUC-Afu-009099	Aspergillus fumigatus	28.57	1.00e-17	85.10
IUUC-Ani-009276	Aspergillus nidulans	28.57	1.00e-17	85.50
IUUC-Bgr-012058	Blumeria graminis	26.02	2.00e-14	74.70
IUUC-Bta-012674	Bos taurus	93.46	0.00e+00	2083.00
IUUC-Cpo-021726	Cavia porcellus	72.15	0.00e+00	1367.00
IUUC-Cne-027023	Cryptococcus neoformans	28.32	5.00e-21	97.10
IUUC-Dme-031672	Drosophila melanogaster	38.07	1.00e-55	211.00
IUUC-Mla-059044	Melampsora laricipopulina	29.88	2.00e-25	111.00
IUUC-Nfi-068331	Neosartorya fischeri	28.31	2.00e-17	84.30
IUUC-Ont-072091	Oreochromis niloticus	47.48	9.00e-103	368.00
IUUC-Pma-094503	Petromyzon marinus	30.42	1.00e-22	102.00
IUUC-Pgr-103400	Puccinia graminis	29.46	4.00e-27	117.00
IUUC-Sce-106197	Saccharomyces cerevisiae	30.22	1.00e-19	92.00
IUUC-Sja-107728	Schizosaccharomyces japonicus	25.84	2.00e-10	61.60
IUUC-Spo-108284	Schizosaccharomyces pombe	26.45	2.00e-21	97.80
IUUC-Ssc-115967	Sus scrofa	81.09	0.00e+00	1630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence