iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004361

UUCD1 version

UUC-AnC-01018

Ensembl Protein ID

ENSACAP00000008126.3

UniProt Accession

G1KHK9; G1KHK9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008213.3	ENSACAT00000008298.3	ENSACAP00000008126.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-64	215.9	105	481
ULD/UDP/UBQ/UBQ_Other	3.50e-08	33.1	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+e+l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKEALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekgd 191
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  +  +++e+   +      +     + k+ksli++ F +++++++kc e +++ +++   ++l
   Q: 192  qgQYLQQDANECWVQMMRVLQQKLEGIEGDTVMETDPGA------SGAAAAPPKKKSLIDQFFSIEFETTMKCTEAEEEEVTKGRENQL 274
           999*********************776666666664444......566789999**********************9999888888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +      +++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 275  QLSCFINQEV--KYLFTGLKLRLQEEITK-----LSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 356
           8887777744..58999999999998887.....7899999999********************************************* PP
   S: 262  spfcts.......................peekqke............................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                        +     +                            +  YeL av+ H+G s+ssGHYv++
   Q: 357  YELCTPelqesmvpyrskfkdledkkvnqQ-----TknsskgdgaqkevkyeafsfpddigsnnCGYYELQAVLTHQGrSSSSGHYVSW 440
           ******777777777777766666555540.....05555666666667777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV++v+ e++l+ +g    + aYvl+Y
   Q: 441  VKRKEDEWIKFDDDKVSTVTPEDILRLSGggdwHIAYVLLY 481
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG   +dd ++++ ++k+g+t++++ +
   Q: 6    VNVKWGKEKFDGVELNTDEPPMVFKAQLFALTGVQPDRQKVMVKGGTVKDD-DWGNIKIKNGMTLLMMGS 74
           7899999998999**********************************9999.9**************976 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPLFTVNVKW GKEKFDGVEL NTDEPPMVFK AQLFALTGVQ PDRQKVMVKG GTVKDDDWGN 60
IKIKNGMTLL MMGSAEALPE EPVARPVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGTCGAA GTCCAAAACA TCTAGAGGGA GGGCCCATGT TTGCCCATTC ATTCTAACCT 60
AGCAGTAGAG GCATTCTTTC CCTGCACCTC CGGCCTTTGG CCACTTGGGG CAGCCGCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100558535

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.41	2.00e-38	153.00
IUUC-Aml-002053	Ailuropoda melanoleuca	90.45	0.00e+00	867.00
IUUC-Atr-002725	Amborella trichopoda	42.28	1.00e-100	359.00
IUUC-Apl-004031	Anas platyrhynchos	94.52	0.00e+00	918.00
IUUC-Aly-006176	Arabidopsis lyrata	41.57	9.00e-110	390.00
IUUC-Ath-007658	Arabidopsis thaliana	41.22	1.00e-108	387.00
IUUC-Ago-007796	Ashbya gossypii	32.09	2.00e-59	223.00
IUUC-Acl-008258	Aspergillus clavatus	37.40	2.00e-65	243.00
IUUC-Afl-008732	Aspergillus flavus	35.16	9.00e-83	300.00
IUUC-Afu-008755	Aspergillus fumigatus	35.57	3.00e-85	308.00
IUUC-Ani-009148	Aspergillus nidulans	36.25	4.00e-86	311.00
IUUC-Ang-009878	Aspergillus niger	35.30	4.00e-81	295.00
IUUC-Aor-010239	Aspergillus oryzae	35.16	8.00e-83	301.00
IUUC-Ate-010243	Aspergillus terreus	35.83	4.00e-81	295.00
IUUC-Ame-011327	Astyanax mexicanus	51.71	3.00e-123	434.00
IUUC-Bgr-012231	Blumeria graminis	33.68	6.00e-80	291.00
IUUC-Bta-012553	Bos taurus	89.70	0.00e+00	877.00
IUUC-Bci-013606	Botrytis cinerea	39.23	2.00e-70	259.00
IUUC-Bdi-014567	Brachypodium distachyon	42.02	4.00e-111	394.00
IUUC-Bol-015565	Brassica oleracea	41.43	2.00e-111	396.00
IUUC-Bra-017297	Brassica rapa	41.07	1.00e-110	393.00
IUUC-Cel-018140	Caenorhabditis elegans	41.43	2.00e-101	362.00
IUUC-Cja-019516	Callithrix jacchus	89.13	0.00e+00	885.00
IUUC-Cfa-020808	Canis familiaris	90.10	0.00e+00	884.00
IUUC-Cpo-021688	Cavia porcellus	88.89	0.00e+00	868.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	38.23	3.00e-83	301.00
IUUC-Csa-023429	Chlorocebus sabaeus	89.88	0.00e+00	867.00
IUUC-Cho-024347	Choloepus hoffmanni	89.07	0.00e+00	875.00
IUUC-Cin-025198	Ciona intestinalis	54.47	5.00e-152	530.00
IUUC-Csv-026007	Ciona savignyi	54.51	6.00e-156	543.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	40.59	1.00e-65	243.00
IUUC-Cne-026963	Cryptococcus neoformans	34.86	3.00e-77	282.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.58	1.00e-60	226.00
IUUC-Dre-027647	Danio rerio	84.32	0.00e+00	847.00
IUUC-Dno-029967	Dasypus novemcinctus	89.49	0.00e+00	867.00
IUUC-Dor-030886	Dipodomys ordii	84.13	0.00e+00	706.00
IUUC-Dse-031466	Dothistroma septosporum	35.64	7.00e-58	218.00
IUUC-Dme-032079	Drosophila melanogaster	55.03	9.00e-159	553.00
IUUC-Ete-032351	Echinops telfairi	78.59	0.00e+00	780.00
IUUC-Eca-033461	Equus caballus	89.70	0.00e+00	924.00
IUUC-Eeu-035220	Erinaceus europaeus	67.97	0.00e+00	625.00
IUUC-Fca-036210	Felis catus	90.30	0.00e+00	885.00
IUUC-Fal-037528	Ficedula albicollis	94.13	0.00e+00	902.00
IUUC-Fox-037805	Fusarium oxysporum	39.53	3.00e-71	262.00
IUUC-Fso-038177	Fusarium solani	37.18	7.00e-67	248.00
IUUC-Gmo-038953	Gadus morhua	79.27	0.00e+00	780.00
IUUC-Ggr-039972	Gaeumannomyces graminis	40.42	1.00e-65	244.00
IUUC-Gga-040462	Gallus gallus	92.73	0.00e+00	905.00
IUUC-Gac-041312	Gasterosteus aculeatus	81.41	0.00e+00	816.00
IUUC-Gma-043255	Glycine max	40.60	6.00e-104	370.00
IUUC-Ggo-045458	Gorilla gorilla	74.80	0.00e+00	721.00
IUUC-Hsa-045706	Homo sapiens	90.10	0.00e+00	870.00
IUUC-Hvu-047821	Hordeum vulgare	47.20	7.00e-58	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	87.88	0.00e+00	890.00
IUUC-Lch-050464	Latimeria chalumnae	83.50	0.00e+00	833.00
IUUC-Lpe-051419	Leersia perrieri	41.48	8.00e-107	380.00
IUUC-Loc-052732	Lepisosteus oculatus	82.19	0.00e+00	846.00
IUUC-Lma-053177	Leptosphaeria maculans	40.27	3.00e-69	256.00
IUUC-Laf-053822	Loxodonta africana	90.08	0.00e+00	875.00
IUUC-Mcc-055893	Macaca mulatta	90.08	0.00e+00	868.00
IUUC-Meu-056307	Macropus eugenii	80.20	0.00e+00	777.00
IUUC-Mor-057171	Magnaporthe oryzae	39.33	8.00e-68	251.00
IUUC-Mpo-057415	Magnaporthe poae	40.79	5.00e-71	261.00
IUUC-Mtr-057901	Medicago truncatula	40.55	2.00e-106	379.00
IUUC-Mla-058897	Melampsora laricipopulina	39.47	2.00e-75	276.00
IUUC-Mga-060016	Meleagris gallopavo	93.71	0.00e+00	913.00
IUUC-Mvi-060562	Microbotryum violaceum	39.12	8.00e-65	241.00
IUUC-Mmr-060624	Microcebus murinus	89.49	0.00e+00	920.00
IUUC-Mdo-061809	Monodelphis domestica	91.53	0.00e+00	888.00
IUUC-Mmu-063869	Mus musculus	88.28	0.00e+00	865.00
IUUC-Mac-064876	Musa acuminata	38.60	3.00e-95	342.00
IUUC-Mpu-066480	Mustela putorius furo	89.70	0.00e+00	880.00
IUUC-Mlu-067866	Myotis lucifugus	89.29	0.00e+00	891.00
IUUC-Nfi-068393	Neosartorya fischeri	34.71	1.00e-81	296.00
IUUC-Ncr-068815	Neurospora crassa	40.31	1.00e-69	257.00
IUUC-Nle-070121	Nomascus leucogenys	89.76	5.00e-130	456.00
IUUC-Opr-070712	Ochotona princeps	70.70	8.00e-158	550.00
IUUC-Ont-071544	Oreochromis niloticus	81.71	0.00e+00	778.00
IUUC-Oan-073635	Ornithorhynchus anatinus	90.44	0.00e+00	739.00
IUUC-Ocu-074926	Oryctolagus cuniculus	89.70	0.00e+00	864.00
IUUC-Oba-075633	Oryza barthii	41.31	2.00e-106	379.00
IUUC-Obr-076423	Oryza brachyantha	41.73	9.00e-109	387.00
IUUC-Ogl-077913	Oryza glaberrima	41.33	5.00e-109	387.00
IUUC-Ogu-078435	Oryza glumaepatula	41.31	2.00e-106	379.00
IUUC-Oin-080072	Oryza indica	41.27	2.00e-106	379.00
IUUC-Olo-080535	Oryza longistaminata	38.92	4.00e-92	331.00
IUUC-Ome-081309	Oryza meridionalis	41.31	2.00e-106	379.00
IUUC-Oni-083113	Oryza nivara	41.31	2.00e-106	379.00
IUUC-Opu-083168	Oryza punctata	40.37	1.00e-100	359.00
IUUC-Oru-084253	Oryza rufipogon	41.31	2.00e-106	379.00
IUUC-Osa-085554	Oryza sativa	40.88	4.00e-109	388.00
IUUC-Ola-086998	Oryzias latipes	80.97	0.00e+00	807.00
IUUC-Olu-087818	Ostreococcus lucimarinus	37.40	2.00e-71	262.00
IUUC-Oga-088571	Otolemur garnettii	90.10	0.00e+00	883.00
IUUC-Oar-089526	Ovis aries	90.06	0.00e+00	874.00
IUUC-Ptr-091433	Pan troglodytes	90.08	0.00e+00	868.00
IUUC-Pan-091966	Papio anubis	89.88	0.00e+00	867.00
IUUC-Psi-093458	Pelodiscus sinensis	91.83	0.00e+00	878.00
IUUC-Pma-094343	Petromyzon marinus	69.44	3.00e-120	424.00
IUUC-Pno-095109	Phaeosphaeria nodorum	35.41	4.00e-80	292.00
IUUC-Ppa-095756	Physcomitrella patens	42.11	3.00e-110	391.00
IUUC-Pfo-096514	Poecilia formosa	83.33	0.00e+00	803.00
IUUC-Pab-098477	Pongo abelii	78.98	0.00e+00	686.00
IUUC-Pop-099221	Populus trichocarpa	41.15	2.00e-104	372.00
IUUC-Pca-100791	Procavia capensis	72.33	4.00e-160	556.00
IUUC-Ppe-101812	Prunus persica	40.73	5.00e-107	380.00
IUUC-Pva-102462	Pteropus vampyrus	84.42	0.00e+00	706.00
IUUC-Pgr-103623	Puccinia graminis	41.14	3.00e-76	278.00
IUUC-Ptt-103767	Puccinia triticina	38.99	2.00e-68	253.00
IUUC-Pte-104109	Pyrenophora teres	40.05	1.00e-69	257.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.32	3.00e-69	255.00
IUUC-Rno-105351	Rattus norvegicus	87.88	0.00e+00	844.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.94	2.00e-60	226.00
IUUC-Sha-107491	Sarcophilus harrisii	92.12	0.00e+00	903.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.97	2.00e-80	292.00
IUUC-Spo-108174	Schizosaccharomyces pombe	36.83	4.00e-78	285.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	35.24	1.00e-84	307.00
IUUC-Smo-108805	Selaginella moellendorffii	43.53	3.00e-111	395.00
IUUC-Sit-110361	Setaria italica	41.45	2.00e-111	395.00
IUUC-Sly-110965	Solanum lycopersicum	41.47	1.00e-106	379.00
IUUC-Sar-113355	Sorex araneus	79.30	0.00e+00	626.00
IUUC-Sbi-114778	Sorghum bicolor	41.94	5.00e-110	390.00
IUUC-Sre-115011	Sporisorium reilianum	36.62	3.00e-63	236.00
IUUC-Ssc-116273	Sus scrofa	89.84	0.00e+00	865.00
IUUC-Tgu-117063	Taeniopygia guttata	93.71	0.00e+00	899.00
IUUC-Tru-118381	Takifugu rubripes	81.14	0.00e+00	800.00
IUUC-Tsy-119076	Tarsius syrichta	73.91	2.00e-107	382.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.87	0.00e+00	793.00
IUUC-Tca-121246	Theobroma cacao	41.83	6.00e-109	387.00
IUUC-Tre-121969	Trichoderma reesei	37.56	5.00e-66	245.00
IUUC-Tvi-122543	Trichoderma virens	33.27	7.00e-68	251.00
IUUC-Tae-125484	Triticum aestivum	41.53	1.00e-107	383.00
IUUC-Tur-126128	Triticum urartu	41.38	4.00e-39	155.00
IUUC-Tbe-128030	Tupaia belangeri	82.41	0.00e+00	777.00
IUUC-Ttr-128701	Tursiops truncatus	88.47	0.00e+00	718.00
IUUC-Uma-129657	Ustilago maydis	36.52	1.00e-65	244.00
IUUC-Vda-129723	Verticillium dahliae	36.43	7.00e-60	224.00
IUUC-Vpa-130284	Vicugna pacos	63.80	2.00e-164	572.00
IUUC-Vvi-131037	Vitis vinifera	42.71	2.00e-109	389.00
IUUC-Xtr-132235	Xenopus tropicalis	86.52	0.00e+00	884.00
IUUC-Xma-133840	Xiphophorus maculatus	83.33	0.00e+00	827.00
IUUC-Yli-134453	Yarrowia lipolytica	36.71	2.00e-82	299.00
IUUC-Zma-135669	Zea mays	35.79	3.00e-93	335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence