iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068861

Ensembl Protein ID

EAA32738

UniProt Accession

Q7S8R5; MDV1_NEUCR

Genbank Protein ID

EAA32738.2

Protein Name

Mitochondrial division protein 1

Genbank Nucleotide ID

CM002239

Gene Name

mdv1; NCU07724

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU07724	EAA32738	EAA32738

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-47	154.0	537	570
UBD/Beta-Prp	3.70e-56	189.5	310	653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           gHt++vtcl+f+d +lv+Gs D +i++WDlrtg 
   Q: 537  GHTGPVTCLQFDDVHLVTGSLDRSIRIWDLRTGS 570
           8**********669*****************995 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....................... 82
           ++ +h++ it+++f     l++++ +d++++vwd+  g ++ +l+gh+a v++++++++  +l+tgs D+tik+wdls                       
   Q: 310  SMRAHQDNITALDFDAPFGLMVSAAMDDSVRVWDLNAGRCIGTLEGHTASVRTLQIEDN--FLATGSMDATIKLWDLSkahydpqgsqevdeededlafvn 408
           6889**********777778999999*********************************..9*************************************** PP
   S: 83   .............tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.........................tlsghdgvvncvvv 145
                        + +++ tl++h d++++l+f    d+lvsGs+d+t+r wdl +g c+++                           +g  ++v  ++v
   Q: 409  pndhavdppagsmADCPLFTLEAHLDEITALHFRG--DVLVSGSADKTLRQWDLTKGRCVQTldvmwaaaqatamgssdgpwrqtsrSADGSADFVGALQV 507
           *************999*****************98..***********************************************76666666666766666 PP
   S: 146  hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsi 246
            +  + l+ G++D++vrlWdl++g++ r l g ht++v++l+fd+   +lv+gsld+++++wdl+tg+ +    +++ +++s+ f+  + r+v+++ + ++
   Q: 508  FE--SALACGTADGMVRLWDLRSGQVHRSLVG-HTGPVTCLQFDD--VHLVTGSLDRSIRIWDLRTGS-IFDAYAYDHPITSMMFD--TRRIVCAAGEDVV 600
           66..***************************9.************..9*******************8.777779***********..************* PP
   S: 247  riWdlrsgdllktlqlhn.....ssvisvavlsfgdnvlvlgsedskvniwkl 294
           +++d+  g  + + ++       +s   v  +++ d ++v+g++d+ v +w +
   Q: 601  KVYDKVEGRHWDCGAGITeaekaKSPAIVERVRIRDGYMVEGRQDGVVGVWTC 653
           ****999999999998888887778888888********************86 PP

Organism

Neurospora crassa

Functional Description
(View)

Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).

Protein Sequence
(Fasta)

MANSDQNRDV FPDDVSIDDD TSVISTRGLE AFGRKVTTTA SHLIGPITDP TSHPHYQTAM 60
TEIHKQLQKP TLQRGVFAIA RTTPTDLVRS KLSSKEIQSR ALAYVPDELL RNIPASSNSY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAATTTGTG CCGCATCCAC GCGCGCGAAC TTGGAGCGAG GTACCTTACC TGATCAACCT 60
CTACAACATC GGGCCATCCG CAGCTGCTGC AATTGATTCA GCCTGCCGTG GTTACATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0496--Mitochondrion
KW-1000--Mitochondrion outer membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005741--C:mitochondrial outer membrane

KEGG

ncr:NCU07724

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007941	Ashbya gossypii	33.38	1.00e-96	345.00
IUUC-Acl-008165	Aspergillus clavatus	60.34	0.00e+00	704.00
IUUC-Afl-008726	Aspergillus flavus	66.57	1.00e-143	500.00
IUUC-Afu-009086	Aspergillus fumigatus	50.82	7.00e-152	528.00
IUUC-Ani-009192	Aspergillus nidulans	58.57	0.00e+00	741.00
IUUC-Ang-009540	Aspergillus niger	60.13	0.00e+00	742.00
IUUC-Aor-010128	Aspergillus oryzae	58.18	0.00e+00	695.00
IUUC-Ate-010579	Aspergillus terreus	61.56	0.00e+00	741.00
IUUC-Bgr-012212	Blumeria graminis	61.88	0.00e+00	836.00
IUUC-Bci-013867	Botrytis cinerea	67.58	0.00e+00	890.00
IUUC-Cgl-026600	Colletotrichum gloeosporioides	74.32	0.00e+00	994.00
IUUC-Cne-027030	Cryptococcus neoformans	36.60	1.00e-75	276.00
IUUC-Dse-031481	Dothistroma septosporum	53.68	0.00e+00	682.00
IUUC-Fox-037725	Fusarium oxysporum	70.86	0.00e+00	965.00
IUUC-Fso-038270	Fusarium solani	70.14	0.00e+00	920.00
IUUC-Ggr-039837	Gaeumannomyces graminis	70.44	0.00e+00	926.00
IUUC-Kpa-049115	Komagataella pastoris	42.01	1.00e-128	451.00
IUUC-Lma-053086	Leptosphaeria maculans	59.41	0.00e+00	712.00
IUUC-Mor-056934	Magnaporthe oryzae	71.62	0.00e+00	946.00
IUUC-Mpo-057367	Magnaporthe poae	70.53	0.00e+00	929.00
IUUC-Mla-058916	Melampsora laricipopulina	39.42	6.00e-74	268.00
IUUC-Mvi-060499	Microbotryum violaceum	36.41	2.00e-73	268.00
IUUC-Nfi-068414	Neosartorya fischeri	61.38	0.00e+00	741.00
IUUC-Pno-095117	Phaeosphaeria nodorum	59.36	0.00e+00	737.00
IUUC-Pgr-103442	Puccinia graminis	31.29	1.00e-68	253.00
IUUC-Ptt-103881	Puccinia triticina	35.45	1.00e-82	299.00
IUUC-Pte-104262	Pyrenophora teres	53.29	0.00e+00	630.00
IUUC-Pyt-104679	Pyrenophora triticirepentis	70.80	3.00e-154	536.00
IUUC-Sce-106213	Saccharomyces cerevisiae	32.78	1.00e-92	332.00
IUUC-Sja-107810	Schizosaccharomyces japonicus	31.35	6.00e-71	259.00
IUUC-Spo-108016	Schizosaccharomyces pombe	29.98	4.00e-76	277.00
IUUC-Ssl-108498	Sclerotinia sclerotiorum	66.97	0.00e+00	859.00
IUUC-Sre-115117	Sporisorium reilianum	37.24	5.00e-77	280.00
IUUC-Tre-122068	Trichoderma reesei	67.82	0.00e+00	878.00
IUUC-Tvi-122485	Trichoderma virens	67.55	0.00e+00	897.00
IUUC-Tme-127188	Tuber melanosporum	56.79	0.00e+00	712.00
IUUC-Uma-129325	Ustilago maydis	36.34	2.00e-74	271.00
IUUC-Vda-130011	Verticillium dahliae	71.71	0.00e+00	972.00
IUUC-Yli-134598	Yarrowia lipolytica	41.69	8.00e-127	445.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence