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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106465
UUCD1 version UUC-SaC-00209
Ensembl Protein ID YPL183C
UniProt Accession Q08924; D6W3I6; WDR6_YEAST
Genbank Protein ID CAA97892.1; DAA11252.1
Protein Name Regulator of Ty1 transposition protein 10; Endosomal recycling protein 2; tRNA (guanosine(34)-2'-O)-methyltransferase non-catalytic subunit TRM734
Genbank Nucleotide ID Z73539; BK006949
Gene Name RTT10; ERE2; TRM734; YPL183C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YPL183C YPL183C YPL183C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.90e-23 80.1 177 214
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++s++ +++ ++ ++++s+sdD +i++WDl tg++l
   Q: 177  GHEGSIFYVNLsNNgRYVASCSDDRSIRLWDLETGKQL 214
           8**********9777********************987 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Involved in regulation of Ty1 transposition. Plays also a role in the regulation of the retromer complex and is required for the recycling from endosomes of plasma membrane proteins like CAN1 and MUP1. Required together with TRM7 for the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)).
 Involved in regulation of Ty1 transposition. Plays also a role in the regulation of the retromer complex and is required for the recycling from endosomes of plasma membrane proteins like CAN1 and MUP1. Required together with TRM7 for the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)).
Protein Sequence
(Fasta)
MKDLSHYGPA LCVKFYNDYV LAGYGPFIHV YDYHSATLIN KCRLFHYNKV HGLSLSSEGK 60
ILAYGARSVT IVELEDVLKK ESLVDFERIN SDWITGATFS FDNLQIYLLT CYNKVLICDL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106465|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAAGGACT TGTCTCATTA TGGTCCTGCG CTATGTGTTA AATTTTACAA TGATTATGTT 60
CTAGCTGGTT ATGGGCCTTT CATCCATGTC TATGACTATC ATTCGGCTAC GTTGATTAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106465|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0967--Endosome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0032456--P:endocytic recycling
GO:0008033--P:tRNA processing
KEGG sce:YPL183C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001786 Ailuropoda melanoleuca 19.51 5.00e-25 108.00
IUUC-Atr-003053 Amborella trichopoda 23.90 2.00e-16 80.10
IUUC-Aca-004886 Anolis carolinensis 20.74 2.00e-30 126.00
IUUC-Aly-005509 Arabidopsis lyrata 26.51 2.00e-21 96.70
IUUC-Ath-007109 Arabidopsis thaliana 26.98 3.00e-22 99.00
IUUC-Ago-007817 Ashbya gossypii 43.22 0.00e+00 821.00
IUUC-Acl-008020 Aspergillus clavatus 24.77 7.00e-67 247.00
IUUC-Afl-008608 Aspergillus flavus 24.13 4.00e-32 131.00
IUUC-Afu-009035 Aspergillus fumigatus 24.29 5.00e-63 234.00
IUUC-Ani-009359 Aspergillus nidulans 26.16 7.00e-79 286.00
IUUC-Ang-009692 Aspergillus niger 25.82 5.00e-64 237.00
IUUC-Aor-010056 Aspergillus oryzae 23.62 7.00e-56 210.00
IUUC-Ate-010299 Aspergillus terreus 25.17 3.00e-58 218.00
IUUC-Ame-011051 Astyanax mexicanus 20.50 1.00e-22 100.00
IUUC-Bgr-012077 Blumeria graminis 27.24 2.00e-38 152.00
IUUC-Bta-012793 Bos taurus 19.72 1.00e-27 117.00
IUUC-Bci-013679 Botrytis cinerea 23.12 1.00e-67 249.00
IUUC-Bdi-014401 Brachypodium distachyon 24.55 8.00e-17 81.30
IUUC-Bol-015628 Brassica oleracea 25.86 9.00e-17 80.90
IUUC-Bra-017446 Brassica rapa 24.25 1.00e-19 90.10
IUUC-Cja-018910 Callithrix jacchus 19.48 6.00e-28 117.00
IUUC-Cfa-021260 Canis familiaris 22.40 1.00e-19 90.50
IUUC-Cpo-022205 Cavia porcellus 20.31 5.00e-27 114.00
IUUC-Csa-023510 Chlorocebus sabaeus 19.42 4.00e-26 112.00
IUUC-Cgl-026380 Colletotrichum gloeosporioides 26.37 7.00e-30 123.00
IUUC-Dre-028004 Danio rerio 21.67 2.00e-17 82.80
IUUC-Dno-029804 Dasypus novemcinctus 19.67 2.00e-27 115.00
IUUC-Dor-030512 Dipodomys ordii 21.09 6.00e-22 97.80
IUUC-Dme-032047 Drosophila melanogaster 21.34 2.00e-14 72.80
IUUC-Eca-033727 Equus caballus 19.60 1.00e-22 99.80
IUUC-Eeu-035210 Erinaceus europaeus 21.59 1.00e-24 107.00
IUUC-Fca-035433 Felis catus 19.24 9.00e-28 117.00
IUUC-Fox-037749 Fusarium oxysporum 28.65 3.00e-47 181.00
IUUC-Fso-038164 Fusarium solani 27.32 2.00e-46 179.00
IUUC-Gmo-039180 Gadus morhua 20.95 2.00e-21 96.30
IUUC-Ggr-039801 Gaeumannomyces graminis 23.07 7.00e-37 147.00
IUUC-Gac-042066 Gasterosteus aculeatus 20.58 2.00e-23 102.00
IUUC-Gma-042704 Glycine max 24.51 3.00e-19 89.40
IUUC-Ggo-044942 Gorilla gorilla 19.57 6.00e-26 111.00
IUUC-Hsa-046408 Homo sapiens 19.78 2.00e-28 119.00
IUUC-Hvu-047448 Hordeum vulgare 24.03 5.00e-13 68.20
IUUC-Itr-048756 Ictidomys tridecemlineatus 19.88 6.00e-27 114.00
IUUC-Kpa-049257 Komagataella pastoris 38.96 0.00e+00 646.00
IUUC-Lch-050170 Latimeria chalumnae 21.67 9.00e-48 183.00
IUUC-Loc-052341 Lepisosteus oculatus 22.22 7.00e-13 67.80
IUUC-Lma-053318 Leptosphaeria maculans 23.39 3.00e-56 211.00
IUUC-Laf-054299 Loxodonta africana 19.26 1.00e-26 113.00
IUUC-Mcc-055438 Macaca mulatta 19.24 2.00e-27 116.00
IUUC-Meu-056206 Macropus eugenii 23.17 5.00e-22 97.80
IUUC-Mor-056928 Magnaporthe oryzae 25.35 1.00e-61 229.00
IUUC-Mpo-057438 Magnaporthe poae 23.60 6.00e-14 71.60
IUUC-Mtr-058455 Medicago truncatula 24.37 3.00e-17 82.80
IUUC-Mvi-060438 Microbotryum violaceum 21.41 2.00e-30 126.00
IUUC-Mmr-061353 Microcebus murinus 19.84 1.00e-25 110.00
IUUC-Mdo-062061 Monodelphis domestica 22.67 1.00e-31 129.00
IUUC-Mmu-064386 Mus musculus 19.46 7.00e-28 117.00
IUUC-Mac-065653 Musa acuminata 21.44 1.00e-26 114.00
IUUC-Mpu-066420 Mustela putorius furo 19.65 2.00e-27 115.00
IUUC-Mlu-068104 Myotis lucifugus 19.81 2.00e-26 112.00
IUUC-Nfi-068301 Neosartorya fischeri 25.32 3.00e-63 235.00
IUUC-Ncr-068718 Neurospora crassa 23.34 2.00e-51 196.00
IUUC-Nle-069836 Nomascus leucogenys 21.33 6.00e-25 107.00
IUUC-Ont-071605 Oreochromis niloticus 21.01 5.00e-20 91.70
IUUC-Oan-073645 Ornithorhynchus anatinus 20.45 6.00e-37 147.00
IUUC-Ocu-074708 Oryctolagus cuniculus 22.45 5.00e-18 85.10
IUUC-Oba-075290 Oryza barthii 23.23 3.00e-14 72.80
IUUC-Obr-076647 Oryza brachyantha 24.00 3.00e-14 72.40
IUUC-Ogl-077628 Oryza glaberrima 23.82 2.00e-17 83.20
IUUC-Ogu-078209 Oryza glumaepatula 24.65 2.00e-14 73.60
IUUC-Oin-079342 Oryza indica 24.50 4.00e-17 82.00
IUUC-Olo-080623 Oryza longistaminata 23.74 8.00e-16 76.30
IUUC-Ome-081776 Oryza meridionalis 25.49 6.00e-14 71.60
IUUC-Oni-082311 Oryza nivara 24.50 4.00e-17 82.40
IUUC-Opu-083195 Oryza punctata 25.21 1.00e-17 84.00
IUUC-Oru-085006 Oryza rufipogon 23.80 3.00e-14 72.80
IUUC-Osa-085317 Oryza sativa 24.11 2.00e-17 83.20
IUUC-Ola-087145 Oryzias latipes 21.42 2.00e-33 136.00
IUUC-Olu-087785 Ostreococcus lucimarinus 25.51 3.00e-12 65.90
IUUC-Oga-088206 Otolemur garnettii 19.93 2.00e-27 115.00
IUUC-Oar-089802 Ovis aries 19.69 5.00e-28 118.00
IUUC-Ptr-091528 Pan troglodytes 23.08 5.00e-18 84.70
IUUC-Pan-092782 Papio anubis 19.21 5.00e-26 111.00
IUUC-Psi-093102 Pelodiscus sinensis 23.56 3.00e-20 91.30
IUUC-Pno-095063 Phaeosphaeria nodorum 25.30 3.00e-19 89.00
IUUC-Ppa-095436 Physcomitrella patens 26.65 3.00e-18 86.30
IUUC-Pfo-097423 Poecilia formosa 20.89 2.00e-29 122.00
IUUC-Pab-097763 Pongo abelii 19.49 6.00e-26 111.00
IUUC-Pop-099090 Populus trichocarpa 23.36 9.00e-16 77.80
IUUC-Pca-100173 Procavia capensis 18.88 6.00e-24 104.00
IUUC-Ppe-101580 Prunus persica 23.51 3.00e-17 82.80
IUUC-Pva-102715 Pteropus vampyrus 22.43 3.00e-20 92.40
IUUC-Pgr-103424 Puccinia graminis 26.94 4.00e-18 84.70
IUUC-Pte-104316 Pyrenophora teres 25.17 8.00e-34 137.00
IUUC-Pyt-104676 Pyrenophora triticirepentis 23.28 6.00e-49 187.00
IUUC-Rno-105122 Rattus norvegicus 19.79 3.00e-30 125.00
IUUC-Sha-107208 Sarcophilus harrisii 23.10 3.00e-36 145.00
IUUC-Sja-107771 Schizosaccharomyces japonicus 25.71 9.00e-67 246.00
IUUC-Spo-108272 Schizosaccharomyces pombe 25.47 2.00e-67 248.00
IUUC-Ssl-108576 Sclerotinia sclerotiorum 23.48 5.00e-54 204.00
IUUC-Sit-109932 Setaria italica 20.81 1.00e-22 100.00
IUUC-Sly-111685 Solanum lycopersicum 27.99 7.00e-21 94.70
IUUC-Sar-112998 Sorex araneus 20.09 8.00e-27 114.00
IUUC-Sbi-114074 Sorghum bicolor 24.63 4.00e-18 85.50
IUUC-Ssc-115619 Sus scrofa 22.66 3.00e-19 89.00
IUUC-Tru-118104 Takifugu rubripes 22.06 3.00e-37 148.00
IUUC-Tni-119995 Tetraodon nigroviridis 20.16 3.00e-31 129.00
IUUC-Tca-121790 Theobroma cacao 25.58 2.00e-20 93.20
IUUC-Tre-122080 Trichoderma reesei 24.09 4.00e-63 234.00
IUUC-Tvi-122306 Trichoderma virens 24.10 1.00e-66 246.00
IUUC-Tae-123488 Triticum aestivum 19.85 4.00e-23 101.00
IUUC-Tur-125969 Triticum urartu 20.99 2.00e-15 76.30
IUUC-Tme-126957 Tuber melanosporum 25.61 2.00e-59 222.00
IUUC-Tbe-128082 Tupaia belangeri 23.22 5.00e-13 68.20
IUUC-Ttr-128387 Tursiops truncatus 23.08 3.00e-19 89.40
IUUC-Vda-129804 Verticillium dahliae 22.02 1.00e-33 136.00
IUUC-Vvi-131701 Vitis vinifera 25.60 1.00e-19 90.50
IUUC-Xtr-132622 Xenopus tropicalis 22.27 4.00e-49 187.00
IUUC-Xma-134014 Xiphophorus maculatus 21.05 1.00e-20 93.60
IUUC-Yli-134589 Yarrowia lipolytica 29.07 4.00e-95 340.00
IUUC-Zma-135732 Zea mays 25.15 5.00e-16 78.60
Created Date 25-Jun-2017

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