iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132105

UUCD1 version

UUC-XeT-00954

Ensembl Protein ID

ENSXETP00000052866.2

UniProt Accession

Q6DIV0; Q6DIV0_XENTR

Genbank Protein ID

AAH75435.1; AAI66955.1; CAJ83114.1

Protein Name

Guanine nucleotide binding protein (G protein), beta polypeptide; Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1

Genbank Nucleotide ID

AAMC01014613; BC166955; CR760842

Gene Name

gnb2l1; rack1; TTpA002l04.1-001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000024447.2	ENSXETT00000052866.2	ENSXETP00000052866.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-44	146.8	147	181
UBD/Beta-Prp	1.90e-54	185.0	10	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           Ht++v+c++f    s++++vs+++D+ +kvW+l  
   Q: 147  HTEWVSCVRFspnsSNPIIVSCGWDKMVKVWNLAN 181
           ***********98544****************865 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv 87
           tlkgh+  v +  +  ++ ++++++srd+t++ w++t+  +      r l gh+ +v++v +s+dg++ ++gs D+t+++wdl tg+++
   Q: 10   TLKGHNGWVTQIATTPQFPDMILSSSRDKTVIMWKLTRDETnygvpQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT 98
           7788887776655559999*******************999************************************************ PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllr 173
           + + gh+++vls++fs+++  +vsGs+d+ti++w++  g c ++  ++ h+++v+cv+++p++   ++vs++ D++v++W+l++ kl +
   Q: 99   RRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTL-GVCKYTvQEESHTEWVSCVRFSPNSsnPIIVSCGWDKMVKVWNLANCKLKT 186
           **********************************765.55555436899************998569***************7777776 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
              g h ++ + ++++++g  ++sg++dg+  lwdl +g+ ++tl    d ++ + fs  + + ++++  +si+iWdl+ + ++  l+
   Q: 187  NHIG-HSGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD-SGDVINALCFS-PNRYWLCAATGPSIKIWDLEGKIIVDELK 271
           6676.***********************************999996.45677777777.7889999999********99776666555 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSSSRDKTV IMWKLTRDET NYGVPQRALR 60
GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSADNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTAGGCCC GGTGTCTACC ATCTGTCTCC ATCCTTTGCC GGTGGAGCGG TTTCGGACTC 60
ATCGCAGCCA TGACTGAGCA AATGACACTT CGGGGGACCC TAAAGGGCCA TAATGGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001525--P:angiogenesis
GO:0060027--P:convergent extension involved in gastrulation
GO:0030178--P:negative regulation of Wnt signaling pathway
GO:2000543--P:positive regulation of gastrulation
GO:0051302--P:regulation of cell division
GO:2000114--P:regulation of establishment of cell polarity
GO:0032880--P:regulation of protein localization

KEGG

xtr:448353

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	63.79	8.00e-104	369.00
IUUC-Aml-001935	Ailuropoda melanoleuca	96.21	0.00e+00	641.00
IUUC-Atr-002694	Amborella trichopoda	68.69	5.00e-126	443.00
IUUC-Apl-003918	Anas platyrhynchos	96.09	1.00e-163	568.00
IUUC-Aca-004869	Anolis carolinensis	96.21	0.00e+00	641.00
IUUC-Aly-005671	Arabidopsis lyrata	64.81	6.00e-125	440.00
IUUC-Ath-007105	Arabidopsis thaliana	65.94	1.00e-125	442.00
IUUC-Ago-007720	Ashbya gossypii	56.87	3.00e-103	368.00
IUUC-Acl-008156	Aspergillus clavatus	72.12	7.00e-138	483.00
IUUC-Afl-008684	Aspergillus flavus	71.47	5.00e-137	479.00
IUUC-Afu-008867	Aspergillus fumigatus	73.40	7.00e-140	489.00
IUUC-Ani-009221	Aspergillus nidulans	72.44	2.00e-138	484.00
IUUC-Ang-009843	Aspergillus niger	71.47	2.00e-136	478.00
IUUC-Aor-010193	Aspergillus oryzae	71.47	5.00e-137	479.00
IUUC-Ate-010420	Aspergillus terreus	73.14	4.00e-125	440.00
IUUC-Ame-010884	Astyanax mexicanus	95.58	0.00e+00	637.00
IUUC-Bgr-012064	Blumeria graminis	70.51	1.00e-135	475.00
IUUC-Bta-013357	Bos taurus	96.21	0.00e+00	641.00
IUUC-Bci-013862	Botrytis cinerea	71.47	1.00e-137	482.00
IUUC-Bdi-014690	Brachypodium distachyon	63.30	3.00e-115	407.00
IUUC-Bol-016231	Brassica oleracea	66.56	9.00e-127	446.00
IUUC-Bra-016879	Brassica rapa	66.15	9.00e-126	442.00
IUUC-Cel-018335	Caenorhabditis elegans	69.38	4.00e-123	434.00
IUUC-Cja-019914	Callithrix jacchus	96.21	0.00e+00	641.00
IUUC-Cfa-020755	Canis familiaris	96.21	0.00e+00	641.00
IUUC-Cpo-022377	Cavia porcellus	96.21	0.00e+00	642.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	75.87	2.00e-138	484.00
IUUC-Csa-023025	Chlorocebus sabaeus	96.21	0.00e+00	641.00
IUUC-Cin-025647	Ciona intestinalis	77.71	5.00e-147	513.00
IUUC-Csv-026027	Ciona savignyi	77.39	4.00e-145	506.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	73.85	6.00e-128	449.00
IUUC-Cne-026930	Cryptococcus neoformans	71.79	1.00e-137	482.00
IUUC-Cme-027251	Cyanidioschyzon merolae	63.46	8.00e-122	429.00
IUUC-Dre-028669	Danio rerio	94.64	0.00e+00	634.00
IUUC-Dno-029470	Dasypus novemcinctus	81.39	8.00e-146	509.00
IUUC-Dor-031098	Dipodomys ordii	86.75	2.00e-146	511.00
IUUC-Dse-031255	Dothistroma septosporum	71.47	3.00e-137	481.00
IUUC-Dme-032118	Drosophila melanogaster	77.78	4.00e-149	520.00
IUUC-Ete-033182	Echinops telfairi	79.82	4.00e-103	367.00
IUUC-Eca-033296	Equus caballus	96.00	3.00e-85	306.00
IUUC-Eeu-034771	Erinaceus europaeus	91.80	1.00e-174	604.00
IUUC-Fca-036315	Felis catus	96.21	0.00e+00	641.00
IUUC-Fal-036990	Ficedula albicollis	93.89	6.00e-101	360.00
IUUC-Fox-037702	Fusarium oxysporum	72.76	6.00e-140	489.00
IUUC-Fso-038384	Fusarium solani	73.40	4.00e-140	490.00
IUUC-Gmo-039630	Gadus morhua	94.16	2.00e-176	610.00
IUUC-Ggr-039985	Gaeumannomyces graminis	72.76	1.00e-139	489.00
IUUC-Gga-040540	Gallus gallus	96.21	0.00e+00	641.00
IUUC-Gac-041316	Gasterosteus aculeatus	90.35	1.00e-173	602.00
IUUC-Gma-042872	Glycine max	64.91	6.00e-125	439.00
IUUC-Ggo-045253	Gorilla gorilla	96.21	0.00e+00	641.00
IUUC-Hsa-046809	Homo sapiens	96.21	0.00e+00	641.00
IUUC-Hvu-047683	Hordeum vulgare	63.53	2.00e-116	411.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	96.21	0.00e+00	641.00
IUUC-Kpa-049214	Komagataella pastoris	58.06	2.00e-99	355.00
IUUC-Lch-049634	Latimeria chalumnae	92.74	3.00e-180	623.00
IUUC-Lpe-050762	Leersia perrieri	63.50	9.00e-116	409.00
IUUC-Loc-052163	Lepisosteus oculatus	96.21	0.00e+00	640.00
IUUC-Lma-053113	Leptosphaeria maculans	72.76	5.00e-139	486.00
IUUC-Laf-054422	Loxodonta africana	96.21	0.00e+00	641.00
IUUC-Mcc-055348	Macaca mulatta	96.21	0.00e+00	641.00
IUUC-Meu-056543	Macropus eugenii	96.21	0.00e+00	642.00
IUUC-Mor-057107	Magnaporthe oryzae	73.08	1.00e-140	492.00
IUUC-Mpo-057487	Magnaporthe poae	73.08	4.00e-140	490.00
IUUC-Mtr-058808	Medicago truncatula	65.22	4.00e-125	440.00
IUUC-Mla-058909	Melampsora laricipopulina	71.88	2.00e-138	484.00
IUUC-Mga-059387	Meleagris gallopavo	96.21	0.00e+00	641.00
IUUC-Mvi-060392	Microbotryum violaceum	68.91	3.00e-134	470.00
IUUC-Mmr-061141	Microcebus murinus	85.47	1.00e-135	475.00
IUUC-Mdo-062932	Monodelphis domestica	96.21	0.00e+00	641.00
IUUC-Mmu-064132	Mus musculus	96.21	0.00e+00	641.00
IUUC-Mac-064447	Musa acuminata	61.73	1.00e-109	389.00
IUUC-Mpu-066721	Mustela putorius furo	95.27	0.00e+00	630.00
IUUC-Mlu-068221	Myotis lucifugus	95.58	2.00e-173	600.00
IUUC-Nfi-068344	Neosartorya fischeri	73.40	8.00e-140	489.00
IUUC-Ncr-068722	Neurospora crassa	72.12	4.00e-138	483.00
IUUC-Nle-069865	Nomascus leucogenys	96.21	0.00e+00	641.00
IUUC-Opr-071100	Ochotona princeps	82.02	4.00e-149	520.00
IUUC-Ont-072287	Oreochromis niloticus	94.32	0.00e+00	632.00
IUUC-Oan-072788	Ornithorhynchus anatinus	96.21	0.00e+00	641.00
IUUC-Ocu-073844	Oryctolagus cuniculus	93.69	8.00e-179	619.00
IUUC-Oba-075981	Oryza barthii	60.25	3.00e-104	371.00
IUUC-Obr-076099	Oryza brachyantha	62.08	2.00e-114	405.00
IUUC-Ogl-077804	Oryza glaberrima	63.30	1.00e-116	412.00
IUUC-Ogu-078035	Oryza glumaepatula	64.00	4.00e-116	410.00
IUUC-Oin-079327	Oryza indica	64.00	4.00e-116	410.00
IUUC-Olo-081084	Oryza longistaminata	64.00	4.00e-116	410.00
IUUC-Ome-081366	Oryza meridionalis	63.61	6.00e-117	413.00
IUUC-Oni-082682	Oryza nivara	63.61	6.00e-117	413.00
IUUC-Opu-084010	Oryza punctata	63.30	4.00e-117	414.00
IUUC-Oru-084358	Oryza rufipogon	63.61	6.00e-117	413.00
IUUC-Osa-085296	Oryza sativa	63.61	6.00e-117	413.00
IUUC-Ola-086400	Oryzias latipes	94.01	0.00e+00	631.00
IUUC-Olu-087817	Ostreococcus lucimarinus	75.16	1.00e-141	495.00
IUUC-Oga-088811	Otolemur garnettii	96.21	0.00e+00	641.00
IUUC-Oar-089962	Ovis aries	96.21	0.00e+00	641.00
IUUC-Ptr-091340	Pan troglodytes	96.21	0.00e+00	641.00
IUUC-Pan-091946	Papio anubis	96.21	0.00e+00	640.00
IUUC-Pma-094535	Petromyzon marinus	93.38	1.00e-180	625.00
IUUC-Pno-095100	Phaeosphaeria nodorum	74.53	1.00e-96	345.00
IUUC-Ppa-095588	Physcomitrella patens	75.08	7.00e-140	489.00
IUUC-Pfo-097311	Poecilia formosa	93.69	0.00e+00	630.00
IUUC-Pab-097863	Pongo abelii	96.21	0.00e+00	642.00
IUUC-Pop-099345	Populus trichocarpa	69.04	2.00e-130	457.00
IUUC-Pca-100594	Procavia capensis	95.27	0.00e+00	635.00
IUUC-Ppe-101743	Prunus persica	64.51	6.00e-123	433.00
IUUC-Pva-102746	Pteropus vampyrus	80.44	5.00e-147	513.00
IUUC-Pgr-103375	Puccinia graminis	54.95	5.00e-96	343.00
IUUC-Ptt-103839	Puccinia triticina	71.88	8.00e-137	479.00
IUUC-Pte-104026	Pyrenophora teres	72.76	5.00e-139	486.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	72.76	7.00e-139	486.00
IUUC-Rno-104964	Rattus norvegicus	96.21	0.00e+00	641.00
IUUC-Sce-106224	Saccharomyces cerevisiae	54.46	8.00e-98	349.00
IUUC-Sha-107409	Sarcophilus harrisii	96.21	0.00e+00	641.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	65.81	3.00e-126	444.00
IUUC-Spo-108297	Schizosaccharomyces pombe	63.58	4.00e-122	430.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	71.47	1.00e-137	482.00
IUUC-Smo-109017	Selaginella moellendorffii	70.57	2.00e-129	455.00
IUUC-Sit-110060	Setaria italica	64.00	1.00e-117	416.00
IUUC-Sly-111496	Solanum lycopersicum	68.75	1.00e-127	449.00
IUUC-Stu-112757	Solanum tuberosum	67.19	1.00e-123	435.00
IUUC-Sar-113173	Sorex araneus	96.21	0.00e+00	641.00
IUUC-Sbi-114681	Sorghum bicolor	64.31	8.00e-118	416.00
IUUC-Sre-115107	Sporisorium reilianum	69.87	5.00e-138	483.00
IUUC-Ssc-116218	Sus scrofa	92.11	3.00e-177	613.00
IUUC-Tru-118202	Takifugu rubripes	93.06	1.00e-180	625.00
IUUC-Tni-120260	Tetraodon nigroviridis	91.80	4.00e-179	619.00
IUUC-Tca-120951	Theobroma cacao	67.08	8.00e-128	449.00
IUUC-Tre-121961	Trichoderma reesei	73.40	2.00e-140	491.00
IUUC-Tvi-122447	Trichoderma virens	73.08	1.00e-139	488.00
IUUC-Tae-123560	Triticum aestivum	62.92	1.00e-115	409.00
IUUC-Tur-126335	Triticum urartu	68.15	3.00e-105	374.00
IUUC-Tme-127105	Tuber melanosporum	68.28	1.00e-125	442.00
IUUC-Tbe-128021	Tupaia belangeri	77.23	7.00e-85	306.00
IUUC-Ttr-128637	Tursiops truncatus	84.86	6.00e-159	553.00
IUUC-Uma-129634	Ustilago maydis	70.19	3.00e-138	484.00
IUUC-Vda-129923	Verticillium dahliae	72.44	9.00e-139	486.00
IUUC-Vpa-130410	Vicugna pacos	74.52	2.00e-109	387.00
IUUC-Vvi-131115	Vitis vinifera	65.74	4.00e-127	447.00
IUUC-Xma-133875	Xiphophorus maculatus	93.69	0.00e+00	630.00
IUUC-Yli-134624	Yarrowia lipolytica	60.76	1.00e-118	419.00
IUUC-Zma-134987	Zea mays	63.69	2.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence