iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134588

Ensembl Protein ID

CAG77851

UniProt Accession

Q6C2R8; RAD5_YARLI

Genbank Protein ID

CAG77851.1

Protein Name

DNA repair protein RAD5

Genbank Nucleotide ID

CR382132

Gene Name

RAD5; YALI0F05698g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_F05698g	CAG77851	CAG77851

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	32.21	7.00e-131	463.00	IUUC-Sce-106396
E3 activity/RING/RING	34.92	1.00e-147	518.00	IUUC-Spo-108026

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Yarrowia lipolytica

Functional Description
(View)

Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).

Protein Sequence
(Fasta)

MEPRQKKARF FDSEEDFGPD TKSLIRPGSS HKPGKPASNS LARPTPAPST FRSDLEAFLG 60
PLSDQRFGLL LAKSKGNVEQ AVNIHFDLPE EVQQATSEET AEEAEVSQTT TSGFETTQKP 120

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Nucleotide Sequence
(Fasta)

ATGGAACCCA GGCAAAAAAA AGCCCGGTTT TTCGACTCTG AGGAGGACTT TGGCCCGGAC 60
ACAAAGTCGC TGATTCGCCC CGGAAGCTCA CACAAGCCTG GCAAGCCTGC CAGCAACTCT 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0008270--F:zinc ion binding
GO:0006289--P:nucleotide-excision repair

KEGG

yli:YALI0F05698g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	34.91	3.00e-99	354.00
IUUC-Atr-003139	Amborella trichopoda	30.16	2.00e-98	351.00
IUUC-Aly-005600	Arabidopsis lyrata	33.56	1.00e-100	359.00
IUUC-Ath-007079	Arabidopsis thaliana	33.84	6.00e-98	350.00
IUUC-Ago-007997	Ashbya gossypii	32.97	2.00e-130	458.00
IUUC-Acl-008022	Aspergillus clavatus	33.99	7.00e-162	563.00
IUUC-Afl-008514	Aspergillus flavus	35.53	8.00e-173	599.00
IUUC-Afu-009055	Aspergillus fumigatus	35.37	2.00e-168	584.00
IUUC-Ani-009340	Aspergillus nidulans	34.05	3.00e-166	577.00
IUUC-Ang-009785	Aspergillus niger	36.32	3.00e-175	607.00
IUUC-Aor-010158	Aspergillus oryzae	35.26	5.00e-173	599.00
IUUC-Ate-010536	Aspergillus terreus	33.36	4.00e-151	527.00
IUUC-Bgr-012147	Blumeria graminis	35.25	9.00e-163	565.00
IUUC-Bci-013741	Botrytis cinerea	34.50	2.00e-165	574.00
IUUC-Bdi-014496	Brachypodium distachyon	31.22	1.00e-101	362.00
IUUC-Bol-015995	Brassica oleracea	33.80	5.00e-101	360.00
IUUC-Bra-017004	Brassica rapa	33.02	2.00e-100	358.00
IUUC-Cpo-021361	Cavia porcellus	32.30	2.00e-64	238.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	26.02	2.00e-45	176.00
IUUC-Csv-026168	Ciona savignyi	26.22	5.00e-36	144.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	34.67	1.00e-167	582.00
IUUC-Cne-026886	Cryptococcus neoformans	29.99	2.00e-117	415.00
IUUC-Cme-027110	Cyanidioschyzon merolae	31.84	3.00e-76	278.00
IUUC-Dse-031471	Dothistroma septosporum	35.62	2.00e-170	591.00
IUUC-Dme-031815	Drosophila melanogaster	25.96	1.00e-51	196.00
IUUC-Fal-037486	Ficedula albicollis	29.84	7.00e-60	223.00
IUUC-Fox-038039	Fusarium oxysporum	37.01	3.00e-170	590.00
IUUC-Fso-038179	Fusarium solani	35.71	6.00e-168	583.00
IUUC-Gmo-038544	Gadus morhua	34.03	1.00e-80	292.00
IUUC-Ggr-039735	Gaeumannomyces graminis	35.81	2.00e-164	571.00
IUUC-Gac-042401	Gasterosteus aculeatus	32.11	4.00e-81	294.00
IUUC-Gma-042995	Glycine max	30.57	6.00e-96	343.00
IUUC-Hvu-047747	Hordeum vulgare	35.05	5.00e-100	357.00
IUUC-Kpa-049087	Komagataella pastoris	30.32	3.00e-130	457.00
IUUC-Lpe-051123	Leersia perrieri	34.49	3.00e-100	358.00
IUUC-Loc-052785	Lepisosteus oculatus	32.70	6.00e-79	287.00
IUUC-Lma-052956	Leptosphaeria maculans	36.47	5.00e-176	609.00
IUUC-Meu-056270	Macropus eugenii	30.80	1.00e-63	236.00
IUUC-Mor-057210	Magnaporthe oryzae	34.42	4.00e-174	603.00
IUUC-Mpo-057407	Magnaporthe poae	33.53	1.00e-169	588.00
IUUC-Mtr-058194	Medicago truncatula	31.87	3.00e-86	311.00
IUUC-Mvi-060322	Microbotryum violaceum	29.03	1.00e-76	279.00
IUUC-Mmr-061043	Microcebus murinus	31.44	1.00e-65	243.00
IUUC-Nfi-068354	Neosartorya fischeri	34.70	6.00e-167	579.00
IUUC-Ncr-068844	Neurospora crassa	35.10	2.00e-169	587.00
IUUC-Ont-071782	Oreochromis niloticus	32.65	4.00e-79	287.00
IUUC-Oba-075316	Oryza barthii	33.24	7.00e-96	343.00
IUUC-Obr-076403	Oryza brachyantha	32.82	5.00e-97	347.00
IUUC-Ogl-077508	Oryza glaberrima	34.58	7.00e-101	360.00
IUUC-Ogu-078083	Oryza glumaepatula	33.38	7.00e-98	350.00
IUUC-Oin-079893	Oryza indica	34.72	2.00e-102	365.00
IUUC-Olo-080615	Oryza longistaminata	34.63	7.00e-103	366.00
IUUC-Ome-081448	Oryza meridionalis	31.08	2.00e-86	312.00
IUUC-Oni-082773	Oryza nivara	33.38	1.00e-97	349.00
IUUC-Opu-083675	Oryza punctata	34.76	3.00e-102	364.00
IUUC-Oru-084543	Oryza rufipogon	33.51	6.00e-98	350.00
IUUC-Osa-085686	Oryza sativa	32.28	4.00e-99	353.00
IUUC-Ola-086830	Oryzias latipes	31.71	3.00e-71	261.00
IUUC-Pan-091844	Papio anubis	31.46	1.00e-34	140.00
IUUC-Psi-093626	Pelodiscus sinensis	32.36	4.00e-74	270.00
IUUC-Pma-094750	Petromyzon marinus	32.17	5.00e-26	108.00
IUUC-Pno-094916	Phaeosphaeria nodorum	36.97	3.00e-172	597.00
IUUC-Ppa-095877	Physcomitrella patens	36.03	3.00e-109	388.00
IUUC-Pfo-096540	Poecilia formosa	33.79	4.00e-81	294.00
IUUC-Pop-099537	Populus trichocarpa	31.50	9.00e-105	372.00
IUUC-Ppe-101820	Prunus persica	35.30	2.00e-87	315.00
IUUC-Pte-104242	Pyrenophora teres	39.18	1.00e-154	538.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	36.21	2.00e-173	600.00
IUUC-Sce-106396	Saccharomyces cerevisiae	33.90	6.00e-119	420.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	37.24	5.00e-160	556.00
IUUC-Spo-108026	Schizosaccharomyces pombe	34.29	3.00e-148	517.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	35.67	5.00e-167	580.00
IUUC-Sit-110076	Setaria italica	33.99	5.00e-100	357.00
IUUC-Sly-111031	Solanum lycopersicum	34.03	6.00e-103	367.00
IUUC-Stu-112600	Solanum tuberosum	32.03	3.00e-104	371.00
IUUC-Sbi-114616	Sorghum bicolor	33.70	6.00e-103	367.00
IUUC-Sre-115131	Sporisorium reilianum	34.32	6.00e-93	333.00
IUUC-Tru-117768	Takifugu rubripes	32.17	4.00e-74	271.00
IUUC-Tni-120618	Tetraodon nigroviridis	31.80	1.00e-78	285.00
IUUC-Tca-121137	Theobroma cacao	30.12	9.00e-104	369.00
IUUC-Tre-121896	Trichoderma reesei	34.33	2.00e-163	567.00
IUUC-Tvi-122597	Trichoderma virens	34.91	5.00e-166	576.00
IUUC-Tae-123674	Triticum aestivum	35.00	4.00e-100	357.00
IUUC-Tur-125999	Triticum urartu	34.58	6.00e-99	353.00
IUUC-Tme-126953	Tuber melanosporum	36.12	1.00e-170	592.00
IUUC-Tbe-127642	Tupaia belangeri	31.49	8.00e-30	124.00
IUUC-Uma-129629	Ustilago maydis	33.79	2.00e-92	332.00
IUUC-Vda-129849	Verticillium dahliae	33.59	4.00e-155	540.00
IUUC-Vvi-131508	Vitis vinifera	32.55	4.00e-96	344.00
IUUC-Xma-133384	Xiphophorus maculatus	34.02	4.00e-82	297.00
IUUC-Zma-135801	Zea mays	32.83	1.00e-95	342.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence