iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125676

Ensembl Protein ID

TRIAE_CS42_U_TGACv1_641684_AA2101450.3

UniProt Accession

A0A1D6DCQ0; A0A1D6DCQ0_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_U_TGACv1_641684_AA2101450	TRIAE_CS42_U_TGACv1_641684_AA2101450.1	TRIAE_CS42_U_TGACv1_641684_AA2101450.1
TRIAE_CS42_U_TGACv1_641684_AA2101450	TRIAE_CS42_U_TGACv1_641684_AA2101450.3	TRIAE_CS42_U_TGACv1_641684_AA2101450.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.90e-168	562.3	463	950

Active Site

Position(s)	Description	Evidence
644	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfra 66
           YD Q+ ++G++ q+k+++a+ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr+
   Q: 463  YDAQVSVFGSKLQKKMEEANTFVVGSGALGCEFLKNLALMGVscsskGKLTITDDDIIEKSNLSRQFLFRD 533
           *********************************************************************** PP
   S: 67   edvgksKAevaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnar 134
           +++g+ K+ vaa a++ +np  +++a +++ ++ +e+++   F + +dvV++aldn+ ar++++ +cl+ +
   Q: 534  WNIGQAKSTVAATAANAINPGLHIDALQNRACPYTENVFhdtFWEGLDVVINALDNVNARMYMDMRCLYFQ 604
           *************************************8899999999************************ PP
   S: 135  vpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa............vlf 193
           +pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa              +
   Q: 605  KPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsefegllektpNEV 675
           *******************************************************************9999 PP
   S: 194  nklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdi 264
           n +l++ a+      k   ++ +e +++v++ l++ + ++f+++i++a+ +f+ +++n +kql+  f+ d 
   Q: 676  NSFLSNPAQYAAAMRKAGDAQARELLERVSECLNKDRCSTFDDCISWARLKFEDYFSNRVKQLTFTFPEDA 746
           9999999999999999******************************************************* PP
   S: 265  vtkskspfwv......................................................sfcsnae 281
            t+ ++pfw+                                                       +++++ 
   Q: 747  ATSMGAPFWSapkrfpralqfsaadqshlnfimsasilraesfgvaipewakntskladvvqkiIVPTFEP 817
           **********9*****9999999999999999999999999999999988887776666666663333333 PP
   S: 282  alqvpekvekdeevvkasap.....lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlr 343
           ++ v+  ++++  ++++++      ++ ll++l++ +k+  +g +++ ++fekddd   ++dl+  +an+r
   Q: 818  KQGVNIVTDEKASNLSSTSVddvavIEDLLAKLQEYAKRlpPGFQMKPIQFEKDDDTnfHMDLISGLANMR 888
           33333333333333333322455677778888888887655899*************************** PP
   S: 344  aeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           a +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  + e ++n+f ++a+
   Q: 889  ARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVMAGehPVEDYRNTFANLAL 950
           ********.**************************************999999*****99875 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MGCLRRLLRR GLLAMLPSKR PSDAAAGDEN GRGGDAKRPR LGETEGAGGS GGRNGAAPRE 60
IDEDLHSRQL AVYGRETMRR LFASDVLVSG LNGLGAEIAK NLALAGVKSV TIHDVKNVEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCAACTC CAAACGCGCT GCCAACACCA GCGCCGCCTC CCCCTTCCCC CCTCCCTCCC 60
CCCCGCCGCC CGCCCCACGA ATCAATACTC CCTCCCGAAG CTCCCACGCC GCCCGGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000144	Aegilops tauschii	99.50	0.00e+00	2019.00
IUUC-Ago-007873	Ashbya gossypii	45.11	0.00e+00	825.00
IUUC-Acl-008181	Aspergillus clavatus	44.88	0.00e+00	828.00
IUUC-Afu-009065	Aspergillus fumigatus	44.95	0.00e+00	850.00
IUUC-Ani-009371	Aspergillus nidulans	45.46	0.00e+00	815.00
IUUC-Ang-009737	Aspergillus niger	45.68	0.00e+00	827.00
IUUC-Bgr-012281	Blumeria graminis	42.98	0.00e+00	811.00
IUUC-Cho-024682	Choloepus hoffmanni	36.50	2.00e-103	370.00
IUUC-Csv-026084	Ciona savignyi	42.72	0.00e+00	839.00
IUUC-Dme-032045	Drosophila melanogaster	44.60	0.00e+00	848.00
IUUC-Eeu-035323	Erinaceus europaeus	41.35	9.00e-157	548.00
IUUC-Ggr-039823	Gaeumannomyces graminis	44.83	0.00e+00	877.00
IUUC-Kpa-049112	Komagataella pastoris	44.99	0.00e+00	843.00
IUUC-Lma-053315	Leptosphaeria maculans	44.88	0.00e+00	869.00
IUUC-Mor-057269	Magnaporthe oryzae	44.07	0.00e+00	850.00
IUUC-Mpo-057435	Magnaporthe poae	44.99	0.00e+00	854.00
IUUC-Mvi-060437	Microbotryum violaceum	43.60	0.00e+00	819.00
IUUC-Nfi-068407	Neosartorya fischeri	44.98	0.00e+00	830.00
IUUC-Ncr-068698	Neurospora crassa	45.76	0.00e+00	864.00
IUUC-Oan-073268	Ornithorhynchus anatinus	40.94	0.00e+00	639.00
IUUC-Oba-075934	Oryza barthii	89.40	0.00e+00	1854.00
IUUC-Ogl-077762	Oryza glaberrima	89.40	0.00e+00	1854.00
IUUC-Ogu-078305	Oryza glumaepatula	89.20	0.00e+00	1854.00
IUUC-Oin-080154	Oryza indica	89.40	0.00e+00	1854.00
IUUC-Olo-081089	Oryza longistaminata	89.59	0.00e+00	1857.00
IUUC-Oni-082447	Oryza nivara	89.30	0.00e+00	1854.00
IUUC-Opu-083863	Oryza punctata	88.60	0.00e+00	1838.00
IUUC-Oru-084469	Oryza rufipogon	89.49	0.00e+00	1857.00
IUUC-Osa-085625	Oryza sativa	89.49	0.00e+00	1854.00
IUUC-Pno-095154	Phaeosphaeria nodorum	43.61	0.00e+00	845.00
IUUC-Pte-104200	Pyrenophora teres	44.11	0.00e+00	862.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	43.53	0.00e+00	857.00
IUUC-Sce-106245	Saccharomyces cerevisiae	43.40	0.00e+00	852.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	44.47	0.00e+00	851.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.47	0.00e+00	827.00
IUUC-Tgu-116565	Taeniopygia guttata	38.79	0.00e+00	685.00
IUUC-Tsy-119436	Tarsius syrichta	35.16	7.00e-166	578.00
IUUC-Tre-122009	Trichoderma reesei	46.52	0.00e+00	837.00
IUUC-Tme-127055	Tuber melanosporum	43.82	0.00e+00	795.00
IUUC-Tbe-127714	Tupaia belangeri	36.39	1.00e-137	484.00
IUUC-Vpa-130716	Vicugna pacos	38.12	0.00e+00	670.00
IUUC-Xtr-132026	Xenopus tropicalis	38.69	0.00e+00	631.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence