iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-07	28.9	252	287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht+++t ++  +  + +++Gs Dg+++vW++++  +
   Q: 252  HTGPITEIKMdPWgRNFITGSIDGNCYVWNMKSLCC 287
           9*******99865677**************998777 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Component of the transcription/export (TREX) complex, which is at least is formed of SUB2, TEX1 and YRA1 and the THO complex composed of HPR1, MFT1, THO2 and THP1.

Protein Sequence
(Fasta)

MSTIGAVDIL NQKTITSEVA ASVTSKYLQS TFSKGNTSHI EDKRFIHVSS RSHSRFTSTP 60
ITPNEILSLK FHVSGSSMAY SRMDGSLTVW FIKDASFDKS VEVYIPDCCG SDKLATDLSW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACAA TTGGAGCTGT TGATATTCTT AATCAAAAGA CCATAACTTC TGAAGTGGCT 60
GCCTCAGTGA CTTCAAAATA TCTACAAAGT ACGTTTTCTA AAGGTAATAC AAGTCATATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000445--C:THO complex part of transcription export complex
GO:0000346--C:transcription export complex
GO:0006406--P:mRNA export from nucleus
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

sce:YNL253W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000099	Aegilops tauschii	22.76	6.00e-15	72.80
IUUC-Atr-003050	Amborella trichopoda	22.76	4.00e-15	73.20
IUUC-Ago-007751	Ashbya gossypii	29.41	3.00e-36	144.00
IUUC-Bta-013514	Bos taurus	21.24	1.00e-11	61.60
IUUC-Bdi-015049	Brachypodium distachyon	22.71	4.00e-13	67.00
IUUC-Dor-030301	Dipodomys ordii	27.39	8.00e-11	58.90
IUUC-Hvu-047633	Hordeum vulgare	26.09	6.00e-12	62.00
IUUC-Lch-049635	Latimeria chalumnae	23.95	5.00e-12	63.20
IUUC-Mtr-057927	Medicago truncatula	21.72	5.00e-13	66.20
IUUC-Mga-060155	Meleagris gallopavo	23.42	9.00e-13	65.10
IUUC-Mdo-062587	Monodelphis domestica	22.48	4.00e-14	70.10
IUUC-Mac-064579	Musa acuminata	21.64	7.00e-12	62.40
IUUC-Obr-076613	Oryza brachyantha	22.96	2.00e-12	64.70
IUUC-Ogl-077009	Oryza glaberrima	23.33	2.00e-13	67.80
IUUC-Oin-079773	Oryza indica	23.33	2.00e-13	67.80
IUUC-Opu-083813	Oryza punctata	23.33	2.00e-13	67.80
IUUC-Osa-085415	Oryza sativa	23.33	3.00e-13	67.00
IUUC-Oga-087923	Otolemur garnettii	21.90	1.00e-13	68.60
IUUC-Oar-089688	Ovis aries	22.80	2.00e-13	67.80
IUUC-Pma-094465	Petromyzon marinus	24.10	2.00e-13	67.80
IUUC-Sha-106761	Sarcophilus harrisii	20.96	6.00e-13	66.20
IUUC-Sja-107865	Schizosaccharomyces japonicus	21.80	2.00e-10	57.80
IUUC-Sit-110773	Setaria italica	23.51	1.00e-14	72.00
IUUC-Sly-111619	Solanum lycopersicum	23.51	7.00e-16	75.90
IUUC-Stu-112241	Solanum tuberosum	23.13	4.00e-15	73.20
IUUC-Sbi-114842	Sorghum bicolor	23.44	3.00e-15	73.60
IUUC-Tca-121279	Theobroma cacao	22.01	2.00e-13	67.80
IUUC-Tae-124204	Triticum aestivum	22.76	5.00e-15	72.80
IUUC-Tur-126279	Triticum urartu	22.30	1.00e-13	68.60
IUUC-Vvi-131345	Vitis vinifera	21.64	3.00e-14	70.50
IUUC-Yli-134522	Yarrowia lipolytica	19.88	2.00e-08	52.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence