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Tag Content
UUCD2 ID IUUC-Ppa-095321
UUCD1 version UUC-PhP-00562
Ensembl Protein ID PP1S372_51V6.1
UniProt Accession A9STK2; A9STK2_PHYPA
Genbank Protein ID EDQ65462.1
Protein Name Defective in cullin neddylation protein
Genbank Nucleotide ID DS545006
Gene Name PHYPADRAFT_166481
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
PP1S372_51V6 PP1S372_51V6.1 PP1S372_51V6.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/DCUN1 1.60e-80 270.4 55 241
UBD/Alpha-Helix/UBA 7.20e-07 29.9 10 46
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/DCUN1
   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkd 96
           ++++lee++ +Ykd ++d+i+++g++ fc+dl+vdp d+++Lv++w+++a t+cefsr+ef+ gl++lg+ds+ kl++ l++l+ elkde+kf++
   Q: 55   DPRHLEEFYLKYKDAYSDMILVDGVSAFCDDLQVDPGDVVMLVISWHMKAVTMCEFSRQEFIGGLQSLGVDSLYKLKHLLPSLRAELKDEHKFRE 149
           6799******************************************************************************************* PP
   S: 97   iYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           iY+f+fn+ak+kgqksl+ldta+ +w+Ll+aer ++l++ w++fL+ +++k+iskDtW++lLefsk+i++ lsnYd+egaWP+liDefveyl
   Q: 150  IYNFSFNWAKEKGQKSLALDTALGMWRLLFAERLWPLVESWCQFLQAKHNKAISKDTWAQLLEFSKTIDPTLSNYDAEGAWPYLIDEFVEYL 241
           ******************************************************************************************97 PP
   

   UBD/Alpha-Helix/UBA
   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q++  +G ++++al+aL a+++nle A e +++
   Q: 10   DKVQQFMTiTGANEKAALTALKASDWNLEGAFEIFYN 46
           89******************************99986 PP
   
Organism Physcomitrella patens
Functional Description
(View)

Functional Description


     Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
 Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
Protein Sequence
(Fasta)
MNKLGRGHRD KVQQFMTITG ANEKAALTAL KASDWNLEGA FEIFYNQLPA RPVTDPRHLE 60
EFYLKYKDAY SDMILVDGVS AFCDDLQVDP GDVVMLVISW HMKAVTMCEF SRQEFIGGLQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ppa-095321|E3,DCUN1;UBD,UBA|Physcomitrella patens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACAATTATCC CAATTTTACC GCCCGGCGTC ATTCCCTCCC TCACTTCCTC ACTCCACCTC 60
TGGTGTGTTC CTTGCTTTGC CAGGCCCCAA CGGACTCTCC CATTAGGGTT CCGGGGTGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ppa-095321|E3,DCUN1;UBD,UBA|Physcomitrella patens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
PROSITE

PS51229--DCUN1
Pfam

PF03556--Cullin_binding
Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
KEGG ppp:PHYPADRAFT_166481
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000561 Aegilops tauschii 73.39 1.00e-109 388.00
IUUC-Atr-002697 Amborella trichopoda 77.48 3.00e-50 189.00
IUUC-Apl-003933 Anas platyrhynchos 43.55 1.00e-57 215.00
IUUC-Ago-007806 Ashbya gossypii 26.02 9.00e-18 82.80
IUUC-Ani-009241 Aspergillus nidulans 25.68 7.00e-23 100.00
IUUC-Bdi-014138 Brachypodium distachyon 72.40 1.00e-108 384.00
IUUC-Cja-018854 Callithrix jacchus 44.35 6.00e-59 219.00
IUUC-Cre-022620 Chlamydomonas reinhardtii 45.31 5.00e-63 233.00
IUUC-Csa-023108 Chlorocebus sabaeus 43.95 2.00e-58 218.00
IUUC-Cin-025269 Ciona intestinalis 40.96 4.00e-56 210.00
IUUC-Cne-026950 Cryptococcus neoformans 37.02 7.00e-39 153.00
IUUC-Dor-030143 Dipodomys ordii 43.55 2.00e-58 218.00
IUUC-Fal-036715 Ficedula albicollis 43.36 5.00e-58 216.00
IUUC-Fox-037884 Fusarium oxysporum 32.67 3.00e-17 80.50
IUUC-Fso-038150 Fusarium solani 29.47 2.00e-18 85.90
IUUC-Gmo-038885 Gadus morhua 46.59 3.00e-61 227.00
IUUC-Ggo-044972 Gorilla gorilla 44.18 6.00e-59 219.00
IUUC-Hsa-046994 Homo sapiens 44.58 3.00e-59 221.00
IUUC-Itr-047902 Ictidomys tridecemlineatus 45.14 5.00e-59 219.00
IUUC-Kpa-049127 Komagataella pastoris 28.11 3.00e-27 114.00
IUUC-Lch-050600 Latimeria chalumnae 45.20 5.00e-60 223.00
IUUC-Lpe-051540 Leersia perrieri 75.90 2.00e-113 400.00
IUUC-Lma-053103 Leptosphaeria maculans 28.85 1.00e-24 105.00
IUUC-Mor-056909 Magnaporthe oryzae 28.57 5.00e-22 97.40
IUUC-Mpo-057299 Magnaporthe poae 27.04 5.00e-21 94.00
IUUC-Mga-060072 Meleagris gallopavo 43.95 6.00e-58 216.00
IUUC-Ncr-068780 Neurospora crassa 25.63 1.00e-17 82.40
IUUC-Nle-069475 Nomascus leucogenys 43.97 5.00e-59 219.00
IUUC-Ont-071408 Oreochromis niloticus 44.76 2.00e-59 221.00
IUUC-Oba-074993 Oryza barthii 75.20 2.00e-113 400.00
IUUC-Obr-076341 Oryza brachyantha 75.20 7.00e-113 399.00
IUUC-Ogl-077099 Oryza glaberrima 75.20 2.00e-113 400.00
IUUC-Oin-079441 Oryza indica 75.60 8.00e-114 402.00
IUUC-Olo-081037 Oryza longistaminata 75.60 8.00e-114 402.00
IUUC-Ome-081357 Oryza meridionalis 75.60 8.00e-114 402.00
IUUC-Oni-082632 Oryza nivara 75.20 3.00e-113 399.00
IUUC-Opu-083351 Oryza punctata 75.32 4.00e-106 376.00
IUUC-Oru-084306 Oryza rufipogon 75.60 8.00e-114 402.00
IUUC-Osa-085307 Oryza sativa 75.60 8.00e-114 402.00
IUUC-Ola-086371 Oryzias latipes 44.35 1.00e-58 218.00
IUUC-Ptr-091595 Pan troglodytes 43.95 3.00e-58 217.00
IUUC-Pma-094196 Petromyzon marinus 39.78 2.00e-41 161.00
IUUC-Pca-100218 Procavia capensis 42.74 6.00e-57 213.00
IUUC-Pgr-103633 Puccinia graminis 26.76 2.00e-20 92.40
IUUC-Pte-104398 Pyrenophora teres 30.30 1.30e-01 26.60
IUUC-Pyt-104428 Pyrenophora triticirepentis 29.89 2.00e-21 95.10
IUUC-Sce-106358 Saccharomyces cerevisiae 26.59 2.00e-23 101.00
IUUC-Sit-110052 Setaria italica 73.60 4.00e-113 399.00
IUUC-Stu-112517 Solanum tuberosum 60.00 3.00e-94 336.00
IUUC-Sbi-114113 Sorghum bicolor 73.60 5.00e-112 395.00
IUUC-Tgu-117196 Taeniopygia guttata 43.75 5.00e-58 216.00
IUUC-Tni-120315 Tetraodon nigroviridis 42.97 2.00e-57 214.00
IUUC-Tre-121986 Trichoderma reesei 32.00 7.00e-21 94.00
IUUC-Tvi-122607 Trichoderma virens 29.64 6.00e-25 107.00
IUUC-Tae-125740 Triticum aestivum 62.98 6.00e-104 369.00
IUUC-Tur-126375 Triticum urartu 56.92 5.00e-99 353.00
IUUC-Tme-126878 Tuber melanosporum 33.20 2.00e-35 142.00
IUUC-Vda-129929 Verticillium dahliae 32.63 3.00e-22 98.60
IUUC-Yli-134595 Yarrowia lipolytica 32.20 3.00e-33 134.00
Created Date 25-Jun-2017

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