iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065752

Ensembl Protein ID

ENSMPUP00000008663.1

UniProt Accession

M3YBF6; M3YBF6_MUSPF

Genbank Protein ID

ENSMPUP00000008663

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01095358

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008733.1	ENSMPUT00000008805.1	ENSMPUP00000008663.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.70e-10	39.7	68	140
E3 activity/RING/RING	5.20e-07	30.1	73	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
            ee  C+I l lM++Pv +++G++y  ++I  +l+++g          cP +r+p++  +l Pn+ l +li+a
   Q: 68   KEEATCAICLSLMSEPVSISCGHSYCNQCIMSFLENQGPvdtssntfPCPHCRAPFRLASLRPNKQLGSLIEA 140
           68899*****************************99999999999999*******************999987 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...pglknssskefrCPlCr 46
           CaiCl+ +++ p++ +CgH ++ +C+  +   +g+ + ss++f CP Cr
   Q: 73   CAICLSLMSE-PVSISCGHSYCNQCIMSFlenQGPVDTSSNTFPCPHCR 120
           ********99.**************9444666699999**********8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPQGLILGLR LCAGCLGRSY VLCWAQGLPP PHVPAGHDEP LGCRAAQVSI PYWNLSGKAM 60
ASATKKMKEE ATCAICLSLM SEPVSISCGH SYCNQCIMSF LENQGPVDTS SNTFPCPHCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTCAAG GCCTCATTCT GGGTCTTCGT CTGTGCGCTG GTTGCCTCGG GAGAAGCTAT 60
GTCCTGTGCT GGGCGCAGGG CCTGCCACCA CCCCATGTGC CAGCGGGACA CGATGAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	89.46	0.00e+00	863.00
IUUC-Ago-007781	Ashbya gossypii	36.08	6.00e-09	55.50
IUUC-Bta-012574	Bos taurus	76.09	0.00e+00	734.00
IUUC-Cja-019759	Callithrix jacchus	72.41	0.00e+00	665.00
IUUC-Cfa-020431	Canis familiaris	84.70	0.00e+00	802.00
IUUC-Cpo-022541	Cavia porcellus	61.73	8.00e-174	603.00
IUUC-Csa-023320	Chlorocebus sabaeus	71.12	0.00e+00	690.00
IUUC-Cho-024964	Choloepus hoffmanni	67.99	2.00e-124	438.00
IUUC-Dno-029741	Dasypus novemcinctus	65.38	4.00e-175	607.00
IUUC-Dor-030298	Dipodomys ordii	60.54	8.00e-99	353.00
IUUC-Ete-032493	Echinops telfairi	62.15	5.00e-170	590.00
IUUC-Eca-033962	Equus caballus	76.51	0.00e+00	728.00
IUUC-Eeu-035228	Erinaceus europaeus	67.38	1.00e-130	459.00
IUUC-Fca-036349	Felis catus	80.43	0.00e+00	780.00
IUUC-Ggo-044493	Gorilla gorilla	72.73	0.00e+00	716.00
IUUC-Hsa-046161	Homo sapiens	71.98	0.00e+00	702.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	60.34	3.00e-149	521.00
IUUC-Laf-054150	Loxodonta africana	72.59	0.00e+00	685.00
IUUC-Mcc-055076	Macaca mulatta	71.12	0.00e+00	691.00
IUUC-Mmu-063517	Mus musculus	53.03	1.00e-139	489.00
IUUC-Mlu-067758	Myotis lucifugus	59.54	1.00e-150	527.00
IUUC-Nle-069117	Nomascus leucogenys	72.79	0.00e+00	707.00
IUUC-Opr-071144	Ochotona princeps	66.81	3.00e-179	621.00
IUUC-Ocu-074825	Oryctolagus cuniculus	70.35	0.00e+00	683.00
IUUC-Oga-088744	Otolemur garnettii	67.99	1.00e-118	419.00
IUUC-Oar-089951	Ovis aries	76.09	0.00e+00	735.00
IUUC-Ptr-090519	Pan troglodytes	72.20	0.00e+00	702.00
IUUC-Pan-092059	Papio anubis	71.52	0.00e+00	696.00
IUUC-Pab-098747	Pongo abelii	73.06	0.00e+00	712.00
IUUC-Pca-100294	Procavia capensis	68.17	0.00e+00	657.00
IUUC-Pva-102129	Pteropus vampyrus	66.16	0.00e+00	650.00
IUUC-Sar-113760	Sorex araneus	64.36	2.00e-164	572.00
IUUC-Tsy-119422	Tarsius syrichta	68.97	0.00e+00	651.00
IUUC-Tbe-127628	Tupaia belangeri	60.00	1.00e-95	342.00
IUUC-Ttr-129039	Tursiops truncatus	78.28	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence