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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108322
UUCD1 version UUC-ScP-00286
Ensembl Protein ID SPAC27F1.03c.1:pep
UniProt Accession Q10171; UBLH1_SCHPO
Genbank Protein ID CAA93292.1
Protein Name Probable ubiquitin carboxyl-terminal hydrolase 1
Genbank Nucleotide ID CU329670
Gene Name uch1; SPAC27F1.03c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC27F1.03c SPAC27F1.03c.1 SPAC27F1.03c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexMentha
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
DUB/UCH 31.00 8.00e-25 111.00 IUUC-Hsa-046754
UBD/Other/Other 31.00 8.00e-25 111.00 IUUC-Hsa-046754
DUB/UCH 28.96 9.00e-15 75.10 IUUC-Sce-106412
Active Site
Position(s) Description Evidence
83 Nucleophile ECO:0000255|PROSITE-ProRule:PRU10091}
158 Proton donor ECO:0000255|PROSITE-ProRule:PRU10091}
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity).
 Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity).
Protein Sequence
(Fasta)
MWRPLENTPE VLEPYLQKIG VQDASVFDLF SLEEIPEYIP RPVHALLFVF PSSGTKTIYK 60
GSRILPKDSD KVLWYPQTIP NACGTIGLLH AVSNGELRRK VNENDFIKSL IRTAEGSSIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108322|DUB,UCH;UBD,UBD/Other/Other|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGGTGTTTT GCCTCTTTGC TGACTTCTGA GACCTCTGCC ACGCCTTCCA AACCTGATCA 60
AAAAAGCCTC AATTAGAGCC ATTTATCATT CGAGAAAAAT TACAATGTGG AGGCCTTTAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108322|DUB,UCH;UBD,UBD/Other/Other|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
Interpro

IPR001578--Peptidase_C12_UCH
PROSITE

PS00140--UCH_1
Pfam

PF01088--Peptidase_C12
PRINTS

PR00707--UBCTHYDRLASE
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000502--C:proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG spo:SPAC27F1.03c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000360 Aegilops tauschii 30.40 2.00e-24 103.00
IUUC-Aml-001344 Ailuropoda melanoleuca 31.00 1.00e-26 111.00
IUUC-Atr-002931 Amborella trichopoda 30.04 1.00e-22 97.40
IUUC-Apl-003949 Anas platyrhynchos 32.34 7.00e-23 98.60
IUUC-Aca-004716 Anolis carolinensis 30.53 2.00e-24 103.00
IUUC-Aly-005939 Arabidopsis lyrata 36.80 3.00e-29 119.00
IUUC-Ath-006827 Arabidopsis thaliana 35.93 3.00e-29 119.00
IUUC-Ago-007950 Ashbya gossypii 28.72 6.00e-13 65.50
IUUC-Acl-008305 Aspergillus clavatus 40.00 6.00e-30 122.00
IUUC-Afl-008611 Aspergillus flavus 41.58 3.00e-34 136.00
IUUC-Afu-008945 Aspergillus fumigatus 38.01 1.00e-31 127.00
IUUC-Ani-009339 Aspergillus nidulans 40.19 1.00e-32 130.00
IUUC-Ang-009691 Aspergillus niger 36.32 9.00e-31 124.00
IUUC-Aor-009961 Aspergillus oryzae 42.08 2.00e-34 137.00
IUUC-Ate-010316 Aspergillus terreus 42.57 8.00e-34 134.00
IUUC-Ame-011806 Astyanax mexicanus 30.63 3.00e-25 106.00
IUUC-Bgr-012125 Blumeria graminis 38.57 4.00e-31 126.00
IUUC-Bta-012673 Bos taurus 31.00 6.00e-27 112.00
IUUC-Bci-013734 Botrytis cinerea 39.41 2.00e-32 130.00
IUUC-Bdi-014330 Brachypodium distachyon 32.90 2.00e-27 114.00
IUUC-Bol-015214 Brassica oleracea 34.06 1.00e-28 117.00
IUUC-Bra-017491 Brassica rapa 34.50 1.00e-29 120.00
IUUC-Cel-018302 Caenorhabditis elegans 31.11 6.00e-23 98.60
IUUC-Cja-019642 Callithrix jacchus 31.30 2.00e-18 83.60
IUUC-Cpo-022036 Cavia porcellus 30.13 2.00e-24 103.00
IUUC-Cre-022599 Chlamydomonas reinhardtii 27.60 5.00e-13 65.90
IUUC-Csa-023854 Chlorocebus sabaeus 30.57 8.00e-26 108.00
IUUC-Cho-024548 Choloepus hoffmanni 51.35 1.00e-05 40.80
IUUC-Cin-025545 Ciona intestinalis 29.91 2.00e-23 100.00
IUUC-Cgl-026409 Colletotrichum gloeosporioides 30.43 1.00e-23 101.00
IUUC-Cne-026914 Cryptococcus neoformans 35.38 3.00e-18 83.20
IUUC-Cme-027216 Cyanidioschyzon merolae 30.57 6.00e-21 92.00
IUUC-Dre-028356 Danio rerio 32.46 4.00e-26 108.00
IUUC-Dor-030114 Dipodomys ordii 32.74 4.00e-24 102.00
IUUC-Dse-031461 Dothistroma septosporum 41.21 4.00e-30 122.00
IUUC-Eca-033220 Equus caballus 31.00 8.00e-27 111.00
IUUC-Fca-036421 Felis catus 31.00 1.00e-26 111.00
IUUC-Fal-036773 Ficedula albicollis 32.04 2.00e-23 100.00
IUUC-Fox-037830 Fusarium oxysporum 38.68 2.00e-32 130.00
IUUC-Fso-038259 Fusarium solani 36.54 9.00e-30 123.00
IUUC-Gmo-038848 Gadus morhua 29.05 8.00e-23 98.20
IUUC-Ggr-039832 Gaeumannomyces graminis 35.98 5.00e-24 102.00
IUUC-Gga-041078 Gallus gallus 33.49 7.00e-26 108.00
IUUC-Gac-041629 Gasterosteus aculeatus 30.52 1.00e-22 97.40
IUUC-Gma-043057 Glycine max 34.80 2.00e-25 107.00
IUUC-Ggo-044533 Gorilla gorilla 30.87 1.00e-25 107.00
IUUC-Hsa-046754 Homo sapiens 31.00 1.00e-26 111.00
IUUC-Kpa-049123 Komagataella pastoris 29.58 6.00e-17 78.60
IUUC-Lch-049685 Latimeria chalumnae 32.33 2.00e-27 114.00
IUUC-Lpe-051377 Leersia perrieri 31.25 2.00e-23 100.00
IUUC-Loc-052342 Lepisosteus oculatus 30.84 3.00e-26 109.00
IUUC-Lma-053316 Leptosphaeria maculans 39.41 7.00e-32 128.00
IUUC-Laf-053985 Loxodonta africana 30.87 1.00e-25 107.00
IUUC-Mcc-055888 Macaca mulatta 30.57 1.00e-24 104.00
IUUC-Meu-056478 Macropus eugenii 31.42 7.00e-24 101.00
IUUC-Mor-057271 Magnaporthe oryzae 34.43 8.00e-27 111.00
IUUC-Mpo-057343 Magnaporthe poae 29.83 2.00e-19 86.30
IUUC-Mtr-057713 Medicago truncatula 31.58 7.00e-25 105.00
IUUC-Mla-058942 Melampsora laricipopulina 36.44 7.00e-30 121.00
IUUC-Mga-059702 Meleagris gallopavo 32.34 5.00e-23 98.60
IUUC-Mvi-060249 Microbotryum violaceum 28.19 8.00e-20 88.20
IUUC-Mmr-061284 Microcebus murinus 31.29 7.00e-17 79.00
IUUC-Mmu-063299 Mus musculus 31.44 4.00e-27 112.00
IUUC-Mac-065075 Musa acuminata 34.91 3.00e-27 113.00
IUUC-Mpu-066769 Mustela putorius furo 31.00 1.00e-26 111.00
IUUC-Mlu-066937 Myotis lucifugus 30.57 5.00e-26 108.00
IUUC-Nfi-068320 Neosartorya fischeri 37.13 7.00e-32 128.00
IUUC-Ncr-068673 Neurospora crassa 35.17 2.00e-29 120.00
IUUC-Nle-069686 Nomascus leucogenys 31.74 1.00e-18 84.30
IUUC-Opr-070535 Ochotona princeps 34.97 2.00e-18 83.20
IUUC-Ont-072170 Oreochromis niloticus 31.46 7.00e-24 101.00
IUUC-Oan-073247 Ornithorhynchus anatinus 37.04 1.00e-13 66.20
IUUC-Ocu-074422 Oryctolagus cuniculus 31.44 1.00e-26 111.00
IUUC-Oba-075098 Oryza barthii 30.84 7.00e-23 98.20
IUUC-Obr-076041 Oryza brachyantha 31.91 7.00e-27 111.00
IUUC-Ogl-076980 Oryza glaberrima 31.90 2.00e-25 106.00
IUUC-Ogu-078978 Oryza glumaepatula 28.79 1.00e-19 88.20
IUUC-Oin-079285 Oryza indica 30.84 5.00e-23 98.60
IUUC-Olo-080671 Oryza longistaminata 30.84 1.00e-22 97.80
IUUC-Ome-081428 Oryza meridionalis 29.96 2.00e-21 93.60
IUUC-Oni-082406 Oryza nivara 30.84 7.00e-23 98.20
IUUC-Opu-083305 Oryza punctata 30.84 1.00e-22 97.80
IUUC-Oru-084969 Oryza rufipogon 30.84 7.00e-23 98.20
IUUC-Osa-085830 Oryza sativa 31.90 2.00e-25 106.00
IUUC-Ola-086893 Oryzias latipes 32.86 2.00e-25 106.00
IUUC-Olu-087858 Ostreococcus lucimarinus 31.44 7.00e-25 105.00
IUUC-Oga-088055 Otolemur garnettii 30.87 1.00e-25 107.00
IUUC-Oar-090319 Ovis aries 31.00 4.00e-27 112.00
IUUC-Ptr-091536 Pan troglodytes 31.74 5.00e-18 82.40
IUUC-Pan-092714 Papio anubis 30.43 5.00e-25 105.00
IUUC-Psi-093818 Pelodiscus sinensis 33.19 1.00e-27 114.00
IUUC-Pma-094412 Petromyzon marinus 31.29 1.00e-14 70.10
IUUC-Pno-094997 Phaeosphaeria nodorum 34.84 3.00e-26 110.00
IUUC-Ppa-095519 Physcomitrella patens 31.36 1.00e-26 111.00
IUUC-Pfo-096182 Poecilia formosa 30.59 7.00e-22 95.10
IUUC-Pab-098048 Pongo abelii 31.74 1.00e-18 84.30
IUUC-Pop-099282 Populus trichocarpa 33.48 2.00e-25 107.00
IUUC-Pca-100818 Procavia capensis 36.36 6.00e-06 42.00
IUUC-Ppe-101332 Prunus persica 35.37 8.00e-30 121.00
IUUC-Pva-102954 Pteropus vampyrus 31.30 7.00e-19 85.10
IUUC-Pgr-103430 Puccinia graminis 34.71 1.00e-26 111.00
IUUC-Ptt-103955 Puccinia triticina 34.32 2.00e-26 110.00
IUUC-Pte-104414 Pyrenophora teres 34.85 3.00e-32 129.00
IUUC-Pyt-104587 Pyrenophora triticirepentis 34.76 3.00e-25 106.00
IUUC-Rno-105096 Rattus norvegicus 31.00 2.00e-26 110.00
IUUC-Sce-106412 Saccharomyces cerevisiae 28.57 3.00e-17 80.10
IUUC-Sha-106677 Sarcophilus harrisii 30.58 6.00e-23 98.60
IUUC-Sja-107753 Schizosaccharomyces japonicus 50.22 1.00e-63 233.00
IUUC-Ssl-108641 Sclerotinia sclerotiorum 38.54 5.00e-30 122.00
IUUC-Smo-109283 Selaginella moellendorffii 30.67 2.00e-23 100.00
IUUC-Sit-110834 Setaria italica 30.70 3.00e-24 103.00
IUUC-Sly-111832 Solanum lycopersicum 33.92 2.00e-29 120.00
IUUC-Stu-112526 Solanum tuberosum 33.92 4.00e-28 115.00
IUUC-Sbi-114545 Sorghum bicolor 29.11 2.00e-23 100.00
IUUC-Sre-114961 Sporisorium reilianum 31.91 1.00e-21 94.70
IUUC-Ssc-115255 Sus scrofa 29.63 2.00e-22 97.10
IUUC-Tgu-117003 Taeniopygia guttata 33.18 1.00e-25 107.00
IUUC-Tru-118330 Takifugu rubripes 36.26 2.00e-20 92.40
IUUC-Tni-120042 Tetraodon nigroviridis 32.94 2.00e-17 82.40
IUUC-Tca-120976 Theobroma cacao 36.56 5.00e-31 125.00
IUUC-Tre-122149 Trichoderma reesei 38.76 3.00e-31 126.00
IUUC-Tvi-122450 Trichoderma virens 38.99 3.00e-31 126.00
IUUC-Tae-122693 Triticum aestivum 30.18 5.00e-24 102.00
IUUC-Tur-126250 Triticum urartu 30.40 2.00e-24 103.00
IUUC-Tme-126961 Tuber melanosporum 40.74 9.00e-30 121.00
IUUC-Tbe-128048 Tupaia belangeri 34.97 1.00e-18 84.00
IUUC-Uma-129382 Ustilago maydis 31.96 8.00e-25 105.00
IUUC-Vda-129850 Verticillium dahliae 32.17 2.00e-25 107.00
IUUC-Vpa-130783 Vicugna pacos 31.48 9.00e-12 61.60
IUUC-Vvi-131661 Vitis vinifera 36.09 3.00e-30 122.00
IUUC-Xtr-132428 Xenopus tropicalis 30.70 9.00e-26 108.00
IUUC-Xma-134245 Xiphophorus maculatus 29.49 1.00e-22 97.40
IUUC-Yli-134570 Yarrowia lipolytica 35.62 1.00e-31 127.00
IUUC-Zma-134954 Zea mays 33.33 7.00e-24 101.00
Created Date 25-Jun-2017

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