iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053216

Ensembl Protein ID

CBY02027

UniProt Accession

E5AFN8; E5AFN8_LEPMJ

Genbank Protein ID

CBY02027.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

FP929139

Gene Name

LEMA_P008140.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P008140.1	CBY02027	CBY02027

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-47	162.0	1409	1900
UBD/Alpha-Helix/UBA	5.80e-19	67.0	1708	1747

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel...........wkskkk............avsprellka 76
           tGlkNlgN+CY+NS+LQ+L+++pe+++ +     ++ ++   + p ++l ++l+kl   l           +    +              +p +l++ 
   Q: 1409 TGLKNLGNSCYLNSTLQALFAMPEFKDRYYL-PDQEPPN--APLPAEDLETQLRKLADGLisgryskpdsdV----SvsehspevphqrGLAPAMLKHL 1500
           7**************************9999.3444333..3578999999999999999555555544440....0455555555555********** PP
   S: 77   lkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           +++ ++efs+++qqDa E+l +ll+ ++++                            +   ++  +d F++ ++++++cl c++v  r+++   +s+p
   Q: 1501 IGRGHSEFSTMRQQDAFELLLHLLKLISRSQ---------------------------HVAPHKDPVDAFRFVMEQRLQCLGCKRVRYRTDEQENISIP 1572
           ***************************9988...........................45556667899****************************** PP
   S: 176  vpgkeetkke......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
           vp ++  ++                       +l++cL+ ft ee +e    + c  c +k    k+ ++k++P vL ++  Rf  +  +++++k +  
   Q: 1573 VPIRRIPNEArmdvtdssgkeatqdkeefepvTLKECLDIFTGEELVE----LTCGACGSKEGFMKRSMFKTFPAVLAVNARRF--ELVNWVPTKQDVP 1665
           **9998877799999******************************999....9*******************************..6688********* PP
   S: 253  vefple.Ldlspfcts................................................................................... 267
           v + +e ++ + + ++                                                                                   
   Q: 1666 VIVGDEpFSFDAYKSNglvdgeellpedsdtgagsssskwvpneaalsmleamgfprvrcekalhatgnedaeaasnwlfahmedadiddpvdfnpgsg 1764
           *************99999999999999999999999988888888888888888888888888888877777777777777777777777777777777 PP
   S: 268  .......................................peekqke...................................kkkYeLiavvvHsG.sls 291
                                                        +                                   +  ++L ++v+H+G s++
   Q: 1765 gsapsvmdpdkieslgamgfnapqarqalketggdmeraV-----DwlfshpdapgdfeegggseapveatekampgsdkmPAHFQLQSIVCHKGsSIH 1858
           7666666666666666666666666555555555555550.....055555555555555555555666666666666666****************** PP
   S: 292  sGHYvayvkn....ekgk...WllfdDskVtev.keeevleetg 327
            GHYva+v++    e  +   W+lf+D+kV +  + ee++++ g
   Q: 1859 AGHYVAFVRKqlpnE--QmasWVLFNDEKVAKAvDVEEMKKFAG 1900
           **********66541..2466*********77526788887655 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +e +l  l++MGF+r ++ +aL a+ n ++eaA+++L+ +
   Q: 1708 NEAALSMLEAMGFPRVRCEKALHATgNEDAEAASNWLFAH 1747
           5678889999***************************976 PP

Organism

Leptosphaeria maculans

Protein Sequence
(Fasta)

MEHKVKKRDR DSASGHNRDE APAKRRRQLN GDHHQKLSKL YEDLAAESDD VRFEAAKQII 60
LKFSPESKPH AKDVETVLSR LIKGLCSQRK AARVGFSLTL TELLRELFKS GKNAIEGLDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCACA AGGTCAAGAA AAGGGATCGC GACTCCGCTA GTGGACATAA TAGGGACGAA 60
GCACCTGCAA AGCGACGCCG GCAACTCAAC GGAGATCATC ATCAAAAGCT ATCAAAGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR007015--DNA_pol_V
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF04931--DNA_pol_phi
PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0003677--F:DNA binding
GO:0003887--F:DNA-directed DNA polymerase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006351--P:transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.64	4.00e-101	360.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.28	1.00e-118	419.00
IUUC-Atr-002580	Amborella trichopoda	32.72	2.00e-110	392.00
IUUC-Apl-003774	Anas platyrhynchos	34.80	4.00e-122	430.00
IUUC-Aca-005368	Anolis carolinensis	33.78	4.00e-125	440.00
IUUC-Aly-005727	Arabidopsis lyrata	34.41	5.00e-113	400.00
IUUC-Ath-006974	Arabidopsis thaliana	34.78	2.00e-114	404.00
IUUC-Ago-007890	Ashbya gossypii	31.00	3.00e-101	361.00
IUUC-Acl-008057	Aspergillus clavatus	58.43	0.00e+00	920.00
IUUC-Afl-008547	Aspergillus flavus	58.38	0.00e+00	797.00
IUUC-Afu-008805	Aspergillus fumigatus	55.98	0.00e+00	842.00
IUUC-Ani-009441	Aspergillus nidulans	54.30	0.00e+00	755.00
IUUC-Ang-009720	Aspergillus niger	59.14	0.00e+00	935.00
IUUC-Aor-010111	Aspergillus oryzae	58.67	0.00e+00	967.00
IUUC-Ate-010531	Aspergillus terreus	54.27	0.00e+00	843.00
IUUC-Ame-011893	Astyanax mexicanus	34.67	5.00e-100	357.00
IUUC-Bgr-012183	Blumeria graminis	57.77	0.00e+00	949.00
IUUC-Bta-013179	Bos taurus	33.97	1.00e-116	412.00
IUUC-Bci-013858	Botrytis cinerea	64.05	0.00e+00	1081.00
IUUC-Bdi-014904	Brachypodium distachyon	34.61	1.00e-106	379.00
IUUC-Bol-015296	Brassica oleracea	34.04	8.00e-115	406.00
IUUC-Bra-017939	Brassica rapa	34.37	1.00e-116	412.00
IUUC-Cel-018625	Caenorhabditis elegans	31.09	3.00e-83	301.00
IUUC-Cja-019063	Callithrix jacchus	33.77	4.00e-116	410.00
IUUC-Cfa-020976	Canis familiaris	34.80	1.00e-120	425.00
IUUC-Cpo-022265	Cavia porcellus	34.87	2.00e-120	425.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.20	2.00e-63	234.00
IUUC-Csa-024177	Chlorocebus sabaeus	34.75	4.00e-110	390.00
IUUC-Cho-024702	Choloepus hoffmanni	36.26	1.00e-65	243.00
IUUC-Cin-025411	Ciona intestinalis	33.70	2.00e-103	368.00
IUUC-Csv-026347	Ciona savignyi	32.72	2.00e-105	375.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	62.85	0.00e+00	930.00
IUUC-Cne-026831	Cryptococcus neoformans	45.23	2.00e-177	614.00
IUUC-Cme-027335	Cyanidioschyzon merolae	39.60	6.00e-57	214.00
IUUC-Dre-027982	Danio rerio	32.71	2.00e-98	352.00
IUUC-Dno-029034	Dasypus novemcinctus	34.20	1.00e-119	422.00
IUUC-Dor-030479	Dipodomys ordii	36.78	1.00e-54	206.00
IUUC-Dse-031467	Dothistroma septosporum	62.95	0.00e+00	976.00
IUUC-Dme-032075	Drosophila melanogaster	34.95	7.00e-114	403.00
IUUC-Ete-032865	Echinops telfairi	31.03	4.00e-97	347.00
IUUC-Eca-034059	Equus caballus	34.09	1.00e-117	416.00
IUUC-Eeu-035304	Erinaceus europaeus	35.34	9.00e-111	392.00
IUUC-Fca-035515	Felis catus	33.96	2.00e-118	418.00
IUUC-Fal-037271	Ficedula albicollis	35.19	9.00e-117	412.00
IUUC-Fox-037745	Fusarium oxysporum	61.67	0.00e+00	999.00
IUUC-Fso-038158	Fusarium solani	62.29	0.00e+00	990.00
IUUC-Gmo-039071	Gadus morhua	32.89	9.00e-101	359.00
IUUC-Ggr-040098	Gaeumannomyces graminis	62.97	0.00e+00	944.00
IUUC-Gga-040635	Gallus gallus	34.32	2.00e-124	438.00
IUUC-Gac-042528	Gasterosteus aculeatus	32.21	8.00e-103	366.00
IUUC-Gma-043614	Glycine max	33.17	6.00e-108	383.00
IUUC-Ggo-044602	Gorilla gorilla	34.09	4.00e-119	420.00
IUUC-Hsa-045959	Homo sapiens	34.09	4.00e-119	420.00
IUUC-Hvu-047563	Hordeum vulgare	37.16	5.00e-106	376.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.28	2.00e-120	424.00
IUUC-Kpa-049156	Komagataella pastoris	40.14	2.00e-168	584.00
IUUC-Lch-049648	Latimeria chalumnae	34.92	7.00e-120	423.00
IUUC-Lpe-051523	Leersia perrieri	34.06	3.00e-109	387.00
IUUC-Loc-052072	Lepisosteus oculatus	32.04	1.00e-107	382.00
IUUC-Laf-054327	Loxodonta africana	33.65	2.00e-117	414.00
IUUC-Mcc-055443	Macaca mulatta	33.96	6.00e-119	420.00
IUUC-Meu-056298	Macropus eugenii	34.99	7.00e-82	296.00
IUUC-Mor-057106	Magnaporthe oryzae	61.60	0.00e+00	977.00
IUUC-Mpo-057589	Magnaporthe poae	61.30	0.00e+00	941.00
IUUC-Mtr-058680	Medicago truncatula	34.32	3.00e-113	400.00
IUUC-Mla-058903	Melampsora laricipopulina	43.19	0.00e+00	628.00
IUUC-Mga-059669	Meleagris gallopavo	34.63	3.00e-118	417.00
IUUC-Mvi-060476	Microbotryum violaceum	46.06	7.00e-173	599.00
IUUC-Mmr-060575	Microcebus murinus	34.08	9.00e-119	419.00
IUUC-Mdo-062183	Monodelphis domestica	34.42	5.00e-118	417.00
IUUC-Mmu-063592	Mus musculus	34.12	2.00e-119	422.00
IUUC-Mac-065446	Musa acuminata	31.56	9.00e-100	356.00
IUUC-Mpu-066082	Mustela putorius furo	34.68	1.00e-119	422.00
IUUC-Mlu-067345	Myotis lucifugus	34.43	3.00e-117	414.00
IUUC-Nfi-068558	Neosartorya fischeri	59.27	0.00e+00	912.00
IUUC-Ncr-068960	Neurospora crassa	62.06	0.00e+00	944.00
IUUC-Nle-070173	Nomascus leucogenys	34.55	2.00e-120	424.00
IUUC-Opr-070556	Ochotona princeps	34.48	1.00e-121	428.00
IUUC-Ont-071502	Oreochromis niloticus	32.65	8.00e-102	363.00
IUUC-Oan-072959	Ornithorhynchus anatinus	42.54	1.00e-47	181.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.92	1.00e-121	428.00
IUUC-Oba-075109	Oryza barthii	33.42	2.00e-109	388.00
IUUC-Obr-076292	Oryza brachyantha	34.32	5.00e-104	370.00
IUUC-Ogl-077065	Oryza glaberrima	33.58	4.00e-113	400.00
IUUC-Ogu-078776	Oryza glumaepatula	33.87	1.00e-112	399.00
IUUC-Oin-080048	Oryza indica	33.66	3.00e-112	397.00
IUUC-Olo-080711	Oryza longistaminata	33.20	2.00e-101	362.00
IUUC-Ome-081506	Oryza meridionalis	34.21	5.00e-104	370.00
IUUC-Oni-082320	Oryza nivara	32.61	2.00e-108	385.00
IUUC-Opu-083801	Oryza punctata	33.87	2.00e-103	368.00
IUUC-Oru-085139	Oryza rufipogon	32.49	1.00e-108	385.00
IUUC-Osa-085713	Oryza sativa	33.70	5.00e-114	403.00
IUUC-Ola-086951	Oryzias latipes	32.11	7.00e-97	346.00
IUUC-Olu-087822	Ostreococcus lucimarinus	33.70	3.00e-98	351.00
IUUC-Oga-088625	Otolemur garnettii	34.08	4.00e-119	420.00
IUUC-Oar-089995	Ovis aries	34.16	4.00e-119	420.00
IUUC-Ptr-090640	Pan troglodytes	34.29	3.00e-122	431.00
IUUC-Pan-091974	Papio anubis	34.12	1.00e-119	422.00
IUUC-Psi-093957	Pelodiscus sinensis	34.32	5.00e-126	443.00
IUUC-Pma-094242	Petromyzon marinus	39.69	4.00e-70	256.00
IUUC-Pno-094835	Phaeosphaeria nodorum	84.05	0.00e+00	1227.00
IUUC-Ppa-095901	Physcomitrella patens	35.78	2.00e-123	434.00
IUUC-Pfo-097148	Poecilia formosa	32.77	4.00e-103	367.00
IUUC-Pab-098068	Pongo abelii	31.67	8.00e-99	353.00
IUUC-Pop-098855	Populus trichocarpa	33.25	1.00e-109	389.00
IUUC-Pca-100738	Procavia capensis	34.30	4.00e-85	307.00
IUUC-Ppe-101315	Prunus persica	33.37	1.00e-109	389.00
IUUC-Pva-102154	Pteropus vampyrus	33.73	1.00e-115	409.00
IUUC-Pgr-103343	Puccinia graminis	42.69	7.00e-144	502.00
IUUC-Ptt-103928	Puccinia triticina	37.39	6.00e-133	466.00
IUUC-Pte-104306	Pyrenophora teres	85.35	0.00e+00	1293.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	83.11	0.00e+00	1308.00
IUUC-Rno-105801	Rattus norvegicus	34.47	7.00e-120	423.00
IUUC-Sce-106304	Saccharomyces cerevisiae	33.05	3.00e-110	390.00
IUUC-Sha-107635	Sarcophilus harrisii	34.47	3.00e-118	417.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	44.40	1.00e-174	604.00
IUUC-Spo-108144	Schizosaccharomyces pombe	43.00	7.00e-173	598.00
IUUC-Smo-108703	Selaginella moellendorffii	36.84	6.00e-114	403.00
IUUC-Sit-110728	Setaria italica	33.37	1.00e-110	392.00
IUUC-Sly-111523	Solanum lycopersicum	35.97	4.00e-124	437.00
IUUC-Sar-113733	Sorex araneus	34.41	2.00e-57	216.00
IUUC-Sbi-114419	Sorghum bicolor	33.79	2.00e-108	384.00
IUUC-Sre-115225	Sporisorium reilianum	43.52	1.00e-179	621.00
IUUC-Ssc-115686	Sus scrofa	34.16	2.00e-119	422.00
IUUC-Tgu-117346	Taeniopygia guttata	33.06	3.00e-118	417.00
IUUC-Tru-118350	Takifugu rubripes	31.84	7.00e-104	370.00
IUUC-Tsy-119278	Tarsius syrichta	33.59	3.00e-88	318.00
IUUC-Tni-120658	Tetraodon nigroviridis	31.68	4.00e-96	344.00
IUUC-Tca-121585	Theobroma cacao	34.37	2.00e-110	392.00
IUUC-Tre-122043	Trichoderma reesei	64.34	0.00e+00	956.00
IUUC-Tvi-122303	Trichoderma virens	63.75	0.00e+00	969.00
IUUC-Tae-123798	Triticum aestivum	34.08	3.00e-113	400.00
IUUC-Tur-126732	Triticum urartu	32.29	5.00e-104	370.00
IUUC-Tme-126909	Tuber melanosporum	62.07	0.00e+00	945.00
IUUC-Tbe-127261	Tupaia belangeri	30.80	5.00e-69	254.00
IUUC-Ttr-128295	Tursiops truncatus	29.20	2.00e-86	312.00
IUUC-Uma-129599	Ustilago maydis	46.05	0.00e+00	657.00
IUUC-Vda-129688	Verticillium dahliae	61.74	0.00e+00	938.00
IUUC-Vpa-130170	Vicugna pacos	31.55	2.00e-78	285.00
IUUC-Vvi-131116	Vitis vinifera	34.40	1.00e-110	392.00
IUUC-Xtr-131953	Xenopus tropicalis	32.82	1.00e-106	379.00
IUUC-Xma-133837	Xiphophorus maculatus	32.65	5.00e-103	367.00
IUUC-Yli-134510	Yarrowia lipolytica	45.25	8.00e-177	612.00
IUUC-Zma-135786	Zea mays	34.16	3.00e-103	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence