iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091281

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03032157

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015916.5	ENSPTRT00000029716.5	ENSPTRP00000027418.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-37	125.2	227	258
UBD/Beta-Prp	4.00e-61	206.8	50	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           H ++++++++ +d t+l+s+s+D+t k+WD++
   Q: 227  HDGGIYAISWsPDsTHLLSASGDKTSKIWDVS 258
           99*********999****************85 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 50   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 138
           455666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l  +++
   Q: 139  HNKVINSVDIKQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALggSKA 226
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           h++ +y +s+++++++l+s+s d+t k+wd++ +++v t+   ++
   Q: 227  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGST 271
           *************************************99976554 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

KVFASLPQVE RGVSKIIGGD PKGNNFLYTN GKCVILRNID NPALADIYTE HAHQVVVAKY 60
APSGFYIASG DVSGKLRIWD TTQKEHLLKY EYQPFAGKIK DIAWTEDSKR IAVVGEGREK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGGTGTT CGCCAGCCTC CCGCAGGTGG AGAGGGGCGT CTCCAAGATC ATCGGCGGCG 60
ACCCTAAGGG CAACAATTTT CTGTACACCA ATGGAAAGTG CGTCATCCTA AGGAACATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0042643--C:actomyosin, actin portion
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0040011--P:locomotion
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.47	1.00e-82	300.00
IUUC-Aml-002368	Ailuropoda melanoleuca	96.83	0.00e+00	1184.00
IUUC-Atr-003160	Amborella trichopoda	37.81	5.00e-116	411.00
IUUC-Apl-004012	Anas platyrhynchos	87.33	0.00e+00	1064.00
IUUC-Aca-004707	Anolis carolinensis	83.50	0.00e+00	1046.00
IUUC-Aly-006465	Arabidopsis lyrata	38.07	1.00e-110	393.00
IUUC-Ath-006740	Arabidopsis thaliana	37.58	5.00e-110	391.00
IUUC-Ago-007920	Ashbya gossypii	27.88	1.00e-71	264.00
IUUC-Acl-008262	Aspergillus clavatus	36.26	2.00e-106	379.00
IUUC-Afl-008471	Aspergillus flavus	33.95	4.00e-80	292.00
IUUC-Afu-008989	Aspergillus fumigatus	38.06	5.00e-96	345.00
IUUC-Ani-009167	Aspergillus nidulans	38.20	6.00e-116	410.00
IUUC-Ang-009595	Aspergillus niger	38.32	3.00e-103	369.00
IUUC-Aor-009908	Aspergillus oryzae	37.16	1.00e-103	370.00
IUUC-Ate-010580	Aspergillus terreus	38.02	7.00e-109	389.00
IUUC-Ame-011269	Astyanax mexicanus	61.01	2.00e-133	469.00
IUUC-Bgr-011996	Blumeria graminis	34.15	6.00e-106	377.00
IUUC-Bta-013278	Bos taurus	95.83	0.00e+00	1200.00
IUUC-Bci-013925	Botrytis cinerea	35.86	1.00e-106	380.00
IUUC-Bdi-014659	Brachypodium distachyon	36.08	7.00e-104	370.00
IUUC-Bol-016043	Brassica oleracea	35.96	3.00e-107	382.00
IUUC-Bra-017139	Brassica rapa	37.09	1.00e-109	390.00
IUUC-Cel-018417	Caenorhabditis elegans	41.23	4.00e-124	438.00
IUUC-Cja-019952	Callithrix jacchus	98.00	0.00e+00	1166.00
IUUC-Cfa-020225	Canis familiaris	96.50	0.00e+00	1184.00
IUUC-Cpo-021900	Cavia porcellus	95.33	0.00e+00	1178.00
IUUC-Csa-023028	Chlorocebus sabaeus	99.33	0.00e+00	1177.00
IUUC-Cho-025030	Choloepus hoffmanni	69.00	0.00e+00	763.00
IUUC-Cin-025152	Ciona intestinalis	56.57	6.00e-81	293.00
IUUC-Csv-025986	Ciona savignyi	38.28	1.00e-93	336.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.16	2.00e-110	393.00
IUUC-Cne-026814	Cryptococcus neoformans	34.48	4.00e-97	348.00
IUUC-Dre-027498	Danio rerio	80.95	5.00e-93	333.00
IUUC-Dno-029383	Dasypus novemcinctus	95.50	0.00e+00	1141.00
IUUC-Dor-030633	Dipodomys ordii	94.12	0.00e+00	1092.00
IUUC-Dse-031526	Dothistroma septosporum	38.66	2.00e-116	412.00
IUUC-Dme-031597	Drosophila melanogaster	48.17	2.00e-167	582.00
IUUC-Ete-032780	Echinops telfairi	85.19	0.00e+00	1029.00
IUUC-Eca-034306	Equus caballus	94.84	0.00e+00	1150.00
IUUC-Eeu-034531	Erinaceus europaeus	75.08	1.00e-137	483.00
IUUC-Fca-036301	Felis catus	97.50	0.00e+00	1214.00
IUUC-Fal-037361	Ficedula albicollis	88.02	0.00e+00	1122.00
IUUC-Fox-037924	Fusarium oxysporum	35.78	5.00e-101	361.00
IUUC-Fso-038199	Fusarium solani	35.24	9.00e-98	350.00
IUUC-Gmo-039238	Gadus morhua	72.50	0.00e+00	890.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.35	2.00e-95	342.00
IUUC-Gga-040235	Gallus gallus	88.67	0.00e+00	1094.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.00	0.00e+00	919.00
IUUC-Gma-044189	Glycine max	37.44	1.00e-113	403.00
IUUC-Ggo-044632	Gorilla gorilla	97.50	0.00e+00	1149.00
IUUC-Hsa-045792	Homo sapiens	99.67	0.00e+00	1206.00
IUUC-Hvu-047517	Hordeum vulgare	35.53	2.00e-107	383.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	96.67	0.00e+00	1183.00
IUUC-Kpa-049183	Komagataella pastoris	33.44	7.00e-85	307.00
IUUC-Lch-050428	Latimeria chalumnae	77.00	0.00e+00	1000.00
IUUC-Lpe-051306	Leersia perrieri	36.12	9.00e-109	387.00
IUUC-Loc-052096	Lepisosteus oculatus	72.30	0.00e+00	898.00
IUUC-Lma-053313	Leptosphaeria maculans	39.12	2.00e-116	415.00
IUUC-Laf-054060	Loxodonta africana	93.00	0.00e+00	1130.00
IUUC-Mcc-055619	Macaca mulatta	97.84	0.00e+00	1159.00
IUUC-Meu-056689	Macropus eugenii	78.06	1.00e-179	622.00
IUUC-Mor-056940	Magnaporthe oryzae	35.19	4.00e-96	345.00
IUUC-Mpo-057557	Magnaporthe poae	28.48	9.00e-57	214.00
IUUC-Mtr-057922	Medicago truncatula	36.68	3.00e-110	392.00
IUUC-Mla-059103	Melampsora laricipopulina	33.63	2.00e-76	280.00
IUUC-Mga-060150	Meleagris gallopavo	89.00	0.00e+00	1094.00
IUUC-Mvi-060448	Microbotryum violaceum	30.59	1.00e-73	270.00
IUUC-Mmr-061226	Microcebus murinus	95.33	0.00e+00	1157.00
IUUC-Mdo-062674	Monodelphis domestica	92.33	0.00e+00	1140.00
IUUC-Mmu-064170	Mus musculus	95.33	0.00e+00	1174.00
IUUC-Mac-065124	Musa acuminata	37.99	2.00e-113	402.00
IUUC-Mpu-066001	Mustela putorius furo	93.90	0.00e+00	1171.00
IUUC-Mlu-067253	Myotis lucifugus	94.18	0.00e+00	1172.00
IUUC-Nfi-068550	Neosartorya fischeri	38.07	1.00e-109	390.00
IUUC-Ncr-068948	Neurospora crassa	36.53	7.00e-112	397.00
IUUC-Nle-070115	Nomascus leucogenys	95.13	0.00e+00	1094.00
IUUC-Opr-070254	Ochotona princeps	93.33	0.00e+00	1111.00
IUUC-Ont-071666	Oreochromis niloticus	75.67	0.00e+00	950.00
IUUC-Oan-073594	Ornithorhynchus anatinus	92.79	2.00e-169	588.00
IUUC-Ocu-074824	Oryctolagus cuniculus	94.33	0.00e+00	1127.00
IUUC-Oba-075010	Oryza barthii	36.51	1.00e-109	390.00
IUUC-Obr-076364	Oryza brachyantha	36.89	1.00e-110	393.00
IUUC-Ogl-077019	Oryza glaberrima	36.51	1.00e-109	390.00
IUUC-Ogu-078496	Oryza glumaepatula	36.51	1.00e-109	390.00
IUUC-Oin-080116	Oryza indica	36.68	3.00e-110	392.00
IUUC-Olo-080290	Oryza longistaminata	36.51	2.00e-109	389.00
IUUC-Ome-081969	Oryza meridionalis	36.51	1.00e-109	390.00
IUUC-Oni-082075	Oryza nivara	36.51	8.00e-110	390.00
IUUC-Opu-083959	Oryza punctata	36.56	1.00e-109	390.00
IUUC-Oru-084711	Oryza rufipogon	36.51	1.00e-109	390.00
IUUC-Osa-085958	Oryza sativa	36.68	3.00e-110	392.00
IUUC-Ola-086968	Oryzias latipes	76.29	0.00e+00	961.00
IUUC-Oga-089108	Otolemur garnettii	96.03	0.00e+00	1209.00
IUUC-Oar-089986	Ovis aries	89.98	0.00e+00	1116.00
IUUC-Pan-092585	Papio anubis	99.50	0.00e+00	1180.00
IUUC-Psi-093811	Pelodiscus sinensis	86.81	0.00e+00	1115.00
IUUC-Pma-094542	Petromyzon marinus	69.87	0.00e+00	885.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.62	2.00e-109	389.00
IUUC-Ppa-095876	Physcomitrella patens	36.63	2.00e-111	396.00
IUUC-Pfo-096973	Poecilia formosa	75.29	0.00e+00	982.00
IUUC-Pab-098391	Pongo abelii	99.17	0.00e+00	1181.00
IUUC-Pop-098850	Populus trichocarpa	37.05	1.00e-111	396.00
IUUC-Pca-100257	Procavia capensis	60.60	1.00e-91	330.00
IUUC-Ppe-101578	Prunus persica	38.26	1.00e-115	410.00
IUUC-Pva-102872	Pteropus vampyrus	90.18	0.00e+00	1119.00
IUUC-Pgr-103593	Puccinia graminis	33.50	6.00e-80	291.00
IUUC-Pte-104365	Pyrenophora teres	39.93	7.00e-112	397.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	39.28	5.00e-114	404.00
IUUC-Rno-105737	Rattus norvegicus	96.00	0.00e+00	1209.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.84	1.00e-66	247.00
IUUC-Sha-107084	Sarcophilus harrisii	90.37	0.00e+00	1013.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.94	2.00e-110	392.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.94	6.00e-95	341.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.53	3.00e-106	379.00
IUUC-Smo-109255	Selaginella moellendorffii	34.76	1.00e-99	357.00
IUUC-Sit-109962	Setaria italica	37.60	2.00e-112	399.00
IUUC-Sly-110897	Solanum lycopersicum	38.59	2.00e-116	412.00
IUUC-Stu-111971	Solanum tuberosum	38.42	2.00e-115	409.00
IUUC-Sar-113415	Sorex araneus	73.06	9.00e-110	390.00
IUUC-Sbi-114857	Sorghum bicolor	37.11	4.00e-110	392.00
IUUC-Sre-114900	Sporisorium reilianum	33.67	1.00e-90	327.00
IUUC-Tgu-117256	Taeniopygia guttata	87.50	0.00e+00	1119.00
IUUC-Tru-117871	Takifugu rubripes	70.28	0.00e+00	885.00
IUUC-Tsy-119172	Tarsius syrichta	97.50	3.00e-140	491.00
IUUC-Tni-120339	Tetraodon nigroviridis	70.62	0.00e+00	922.00
IUUC-Tca-121609	Theobroma cacao	37.36	7.00e-113	401.00
IUUC-Tre-122076	Trichoderma reesei	35.89	1.00e-93	337.00
IUUC-Tvi-122528	Trichoderma virens	34.43	4.00e-95	342.00
IUUC-Tae-123530	Triticum aestivum	35.90	1.00e-108	387.00
IUUC-Tur-126845	Triticum urartu	35.45	4.00e-81	295.00
IUUC-Tme-127217	Tuber melanosporum	35.39	5.00e-103	368.00
IUUC-Tbe-127526	Tupaia belangeri	94.18	0.00e+00	1160.00
IUUC-Ttr-128898	Tursiops truncatus	88.19	0.00e+00	1087.00
IUUC-Uma-129631	Ustilago maydis	32.45	7.00e-94	338.00
IUUC-Vda-129732	Verticillium dahliae	36.17	2.00e-92	333.00
IUUC-Vvi-131217	Vitis vinifera	38.42	3.00e-113	402.00
IUUC-Xtr-132860	Xenopus tropicalis	74.80	0.00e+00	941.00
IUUC-Xma-133830	Xiphophorus maculatus	75.63	0.00e+00	985.00
IUUC-Yli-134335	Yarrowia lipolytica	32.78	2.00e-76	280.00
IUUC-Zma-135907	Zea mays	37.27	3.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence