iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107084

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01219213

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000003806.1	ENSSHAT00000004367.1	ENSSHAP00000004323.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-36	122.4	187	217
UBD/Beta-Prp	2.90e-59	200.8	10	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H+++++++++ +d  +l+s+s+D+t k+WD+
   Q: 187  HEGGIYAISWsPDgSHLLSASGDKTAKMWDV 217
           9**********999****************7 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   +++++v + +d+k ++ ++e   ++  v+  +tg+ v  ++g
   Q: 10   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDVAWTEDSKRIAVVGEGreKFGAVFLWDTGSSVGEVTG 98
           566666778*************************998777742334567***********9999999988777888888********** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +++ ++lv+Gs+d+ +  ++ +  +    t   h ++vncv+++pdg+ ++++++D+++ ++d ktg+ +  l  +++
   Q: 99   HNKVINSVDIKQTRpYRLVTGSDDNCAAFFEGPPFKFKF-TIGDHGRFVNCVRFSPDGSRFATAGADGQIYIYDGKTGEKVCALggSKA 186
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk.svrfspnderlvsgssDgsiriWd 250
           h++ +y +s++++g +l+s+s d+t k+wd+ ++++v+t+   ++    ++  + ++++l+s s  g i+  d
   Q: 187  HEGGIYAISWSPDGSHLLSASGDKTAKMWDVGANSVVNTFAMGSTVLDqQLGCLWQKDYLISLSLSGYINYLD 259
           *************************************999765544431444447888888888888887655 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

NPAIADIYTE HAHQVVVAKY APSGFYIASG DVSGKLRIWD TTQKEHLLKY EYQPFAGKIK 60
DVAWTEDSKR IAVVGEGREK FGAVFLWDTG SSVGEVTGHN KVINSVDIKQ TRPYRLVTGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCCGGCCA TCGCAGACAT CTACACGGAG CACGCGCATC AGGTGGTGGT GGCCAAGTAC 60
GCGCCCAGCG GCTTCTACAT CGCTTCCGGA GGTAGGGCCC GGGCTATCTC CCCGCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	34.60	3.00e-77	282.00
IUUC-Aml-002368	Ailuropoda melanoleuca	90.20	0.00e+00	1035.00
IUUC-Atr-003160	Amborella trichopoda	36.71	7.00e-100	357.00
IUUC-Apl-004012	Anas platyrhynchos	85.03	0.00e+00	983.00
IUUC-Aca-004707	Anolis carolinensis	83.24	0.00e+00	966.00
IUUC-Aly-006465	Arabidopsis lyrata	36.82	8.00e-96	344.00
IUUC-Ath-006740	Arabidopsis thaliana	36.47	9.00e-95	340.00
IUUC-Ago-007920	Ashbya gossypii	29.09	2.00e-69	256.00
IUUC-Acl-008262	Aspergillus clavatus	37.46	4.00e-100	358.00
IUUC-Afl-008471	Aspergillus flavus	32.33	1.00e-69	257.00
IUUC-Afu-008989	Aspergillus fumigatus	38.67	8.00e-96	344.00
IUUC-Ani-009167	Aspergillus nidulans	38.64	2.00e-107	382.00
IUUC-Ang-009595	Aspergillus niger	38.82	1.00e-95	343.00
IUUC-Aor-009908	Aspergillus oryzae	37.48	5.00e-99	354.00
IUUC-Ate-010580	Aspergillus terreus	38.45	5.00e-101	363.00
IUUC-Ame-011269	Astyanax mexicanus	59.27	6.00e-113	400.00
IUUC-Bgr-011996	Blumeria graminis	33.74	2.00e-93	336.00
IUUC-Bta-013278	Bos taurus	90.73	0.00e+00	1063.00
IUUC-Bci-013925	Botrytis cinerea	35.09	8.00e-94	337.00
IUUC-Bdi-014659	Brachypodium distachyon	35.10	5.00e-88	318.00
IUUC-Bol-016043	Brassica oleracea	34.73	8.00e-91	327.00
IUUC-Bra-017139	Brassica rapa	36.01	6.00e-94	338.00
IUUC-Cel-018417	Caenorhabditis elegans	41.21	2.00e-113	402.00
IUUC-Cja-019952	Callithrix jacchus	88.77	0.00e+00	1014.00
IUUC-Cfa-020225	Canis familiaris	90.20	0.00e+00	1035.00
IUUC-Cpo-021900	Cavia porcellus	88.77	0.00e+00	1038.00
IUUC-Csa-023028	Chlorocebus sabaeus	90.73	0.00e+00	1018.00
IUUC-Cho-025030	Choloepus hoffmanni	63.02	0.00e+00	638.00
IUUC-Cin-025152	Ciona intestinalis	54.50	1.00e-63	236.00
IUUC-Csv-025986	Ciona savignyi	36.99	8.00e-91	327.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	39.08	6.00e-104	371.00
IUUC-Cne-026814	Cryptococcus neoformans	32.35	2.00e-83	303.00
IUUC-Dre-027498	Danio rerio	83.22	1.00e-73	268.00
IUUC-Dno-029383	Dasypus novemcinctus	88.95	0.00e+00	1003.00
IUUC-Dor-030633	Dipodomys ordii	87.70	0.00e+00	1027.00
IUUC-Dse-031526	Dothistroma septosporum	39.17	5.00e-106	378.00
IUUC-Dme-031597	Drosophila melanogaster	47.15	4.00e-149	521.00
IUUC-Ete-032780	Echinops telfairi	82.00	0.00e+00	939.00
IUUC-Eca-034306	Equus caballus	88.06	0.00e+00	1005.00
IUUC-Eeu-034531	Erinaceus europaeus	70.50	7.00e-132	463.00
IUUC-Fca-036301	Felis catus	90.73	0.00e+00	1065.00
IUUC-Fal-037361	Ficedula albicollis	87.70	0.00e+00	1043.00
IUUC-Fox-037924	Fusarium oxysporum	36.49	2.00e-93	336.00
IUUC-Fso-038199	Fusarium solani	35.43	2.00e-89	323.00
IUUC-Gmo-039238	Gadus morhua	71.00	0.00e+00	805.00
IUUC-Ggr-039830	Gaeumannomyces graminis	36.74	8.00e-88	317.00
IUUC-Gga-040235	Gallus gallus	87.52	0.00e+00	1003.00
IUUC-Gac-042363	Gasterosteus aculeatus	70.11	0.00e+00	827.00
IUUC-Gma-043218	Glycine max	36.41	4.00e-95	342.00
IUUC-Ggo-044632	Gorilla gorilla	88.59	0.00e+00	990.00
IUUC-Hsa-045792	Homo sapiens	90.20	0.00e+00	1031.00
IUUC-Hvu-047517	Hordeum vulgare	35.04	4.00e-93	335.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	90.55	0.00e+00	1035.00
IUUC-Kpa-049183	Komagataella pastoris	32.74	6.00e-80	291.00
IUUC-Lch-050428	Latimeria chalumnae	74.91	0.00e+00	901.00
IUUC-Lpe-051306	Leersia perrieri	36.44	7.00e-96	344.00
IUUC-Loc-052096	Lepisosteus oculatus	69.35	0.00e+00	799.00
IUUC-Lma-053313	Leptosphaeria maculans	38.22	3.00e-100	361.00
IUUC-Laf-054060	Loxodonta africana	86.99	0.00e+00	999.00
IUUC-Mcc-055619	Macaca mulatta	89.20	0.00e+00	1002.00
IUUC-Meu-056689	Macropus eugenii	75.35	1.00e-153	536.00
IUUC-Mor-056940	Magnaporthe oryzae	35.79	2.00e-90	326.00
IUUC-Mpo-057557	Magnaporthe poae	31.30	3.00e-59	223.00
IUUC-Mtr-057922	Medicago truncatula	36.03	8.00e-96	344.00
IUUC-Mla-059103	Melampsora laricipopulina	33.08	6.00e-71	261.00
IUUC-Mga-060150	Meleagris gallopavo	87.70	0.00e+00	1001.00
IUUC-Mvi-060448	Microbotryum violaceum	31.63	2.00e-67	249.00
IUUC-Mmr-061226	Microcebus murinus	86.99	0.00e+00	1012.00
IUUC-Mdo-062674	Monodelphis domestica	92.16	0.00e+00	1044.00
IUUC-Mmu-064170	Mus musculus	89.30	0.00e+00	1035.00
IUUC-Mac-065124	Musa acuminata	36.97	8.00e-97	347.00
IUUC-Mpu-066001	Mustela putorius furo	86.64	0.00e+00	1012.00
IUUC-Mlu-067253	Myotis lucifugus	89.56	0.00e+00	1055.00
IUUC-Nfi-068550	Neosartorya fischeri	39.02	7.00e-101	361.00
IUUC-Ncr-068948	Neurospora crassa	37.50	1.00e-102	367.00
IUUC-Nle-070115	Nomascus leucogenys	88.77	0.00e+00	1011.00
IUUC-Opr-070254	Ochotona princeps	86.45	0.00e+00	974.00
IUUC-Ont-071666	Oreochromis niloticus	73.80	0.00e+00	854.00
IUUC-Oan-073594	Ornithorhynchus anatinus	89.82	2.00e-161	560.00
IUUC-Ocu-074824	Oryctolagus cuniculus	87.88	0.00e+00	980.00
IUUC-Oba-075010	Oryza barthii	36.36	3.00e-96	345.00
IUUC-Obr-076364	Oryza brachyantha	36.91	9.00e-97	347.00
IUUC-Ogl-077019	Oryza glaberrima	36.36	3.00e-96	345.00
IUUC-Ogu-078496	Oryza glumaepatula	36.36	3.00e-96	345.00
IUUC-Oin-080116	Oryza indica	36.54	6.00e-96	344.00
IUUC-Olo-080290	Oryza longistaminata	36.36	9.00e-96	344.00
IUUC-Ome-081969	Oryza meridionalis	36.36	5.00e-96	345.00
IUUC-Oni-082075	Oryza nivara	36.36	4.00e-96	345.00
IUUC-Opu-083959	Oryza punctata	36.77	2.00e-96	346.00
IUUC-Oru-084711	Oryza rufipogon	36.36	3.00e-96	345.00
IUUC-Osa-085958	Oryza sativa	36.54	6.00e-96	344.00
IUUC-Ola-086968	Oryzias latipes	73.26	0.00e+00	857.00
IUUC-Oga-089108	Otolemur garnettii	89.20	0.00e+00	1058.00
IUUC-Oar-089986	Ovis aries	84.86	0.00e+00	984.00
IUUC-Ptr-091281	Pan troglodytes	90.55	0.00e+00	1035.00
IUUC-Pan-092585	Papio anubis	90.73	0.00e+00	1019.00
IUUC-Psi-093811	Pelodiscus sinensis	86.99	0.00e+00	1033.00
IUUC-Pma-094542	Petromyzon marinus	66.78	0.00e+00	790.00
IUUC-Pno-095086	Phaeosphaeria nodorum	36.47	2.00e-94	340.00
IUUC-Ppa-095876	Physcomitrella patens	35.74	9.00e-98	350.00
IUUC-Pfo-096973	Poecilia formosa	73.80	0.00e+00	890.00
IUUC-Pab-098391	Pongo abelii	90.20	0.00e+00	1018.00
IUUC-Pop-098850	Populus trichocarpa	36.84	3.00e-96	345.00
IUUC-Pca-100257	Procavia capensis	58.59	4.00e-86	311.00
IUUC-Ppe-101578	Prunus persica	36.84	1.00e-96	346.00
IUUC-Pva-102872	Pteropus vampyrus	84.82	0.00e+00	988.00
IUUC-Pgr-103593	Puccinia graminis	33.22	6.00e-75	275.00
IUUC-Pte-104365	Pyrenophora teres	37.63	2.00e-93	336.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	37.35	6.00e-97	348.00
IUUC-Rno-105737	Rattus norvegicus	90.02	0.00e+00	1060.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.86	3.00e-63	236.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	36.27	2.00e-102	366.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.15	3.00e-86	312.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	34.91	7.00e-94	337.00
IUUC-Smo-109255	Selaginella moellendorffii	35.73	4.00e-87	315.00
IUUC-Sit-109962	Setaria italica	37.37	1.00e-97	350.00
IUUC-Sly-110897	Solanum lycopersicum	37.26	3.00e-96	345.00
IUUC-Stu-111971	Solanum tuberosum	36.56	2.00e-93	336.00
IUUC-Sar-113415	Sorex araneus	69.74	2.00e-106	379.00
IUUC-Sbi-114857	Sorghum bicolor	36.62	3.00e-94	339.00
IUUC-Sre-114900	Sporisorium reilianum	33.75	6.00e-79	288.00
IUUC-Tgu-117256	Taeniopygia guttata	86.99	0.00e+00	1028.00
IUUC-Tru-117871	Takifugu rubripes	67.74	0.00e+00	790.00
IUUC-Tsy-119172	Tarsius syrichta	91.25	4.00e-134	471.00
IUUC-Tni-120339	Tetraodon nigroviridis	67.56	0.00e+00	822.00
IUUC-Tca-121609	Theobroma cacao	36.16	6.00e-94	338.00
IUUC-Tre-122076	Trichoderma reesei	37.54	7.00e-89	321.00
IUUC-Tvi-122528	Trichoderma virens	35.68	5.00e-89	322.00
IUUC-Tae-124549	Triticum aestivum	35.04	9.00e-94	337.00
IUUC-Tur-126845	Triticum urartu	34.36	1.00e-75	277.00
IUUC-Tme-127217	Tuber melanosporum	35.47	3.00e-93	335.00
IUUC-Tbe-127526	Tupaia belangeri	86.63	0.00e+00	1008.00
IUUC-Ttr-128898	Tursiops truncatus	87.17	0.00e+00	969.00
IUUC-Uma-129631	Ustilago maydis	32.86	3.00e-82	299.00
IUUC-Vda-129732	Verticillium dahliae	36.11	1.00e-85	310.00
IUUC-Vvi-131217	Vitis vinifera	36.56	8.00e-93	334.00
IUUC-Xtr-132860	Xenopus tropicalis	70.90	0.00e+00	835.00
IUUC-Xma-133830	Xiphophorus maculatus	73.62	0.00e+00	886.00
IUUC-Yli-134335	Yarrowia lipolytica	31.47	2.00e-64	239.00
IUUC-Zma-135907	Zea mays	36.56	2.00e-95	342.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence